SMS scnews item created by Andrew Mathas at Fri 9 Nov 2012 1311
Type: Seminar
Distribution: World
Expiry: 23 Nov 2012
Calendar1: 23 Nov 2012 1100-1200
CalLoc1: AGR Carslaw 829
CalTitle1: AGR Seminar: Statistical issues with quantitative proteomics data
Auth: mathas@pmathas.pc (assumed)

AGR Seminar

Statistical issues with quantitative proteomics data

Dr Jean Yee Hwa Yang (The University of Sydney)

Host Venue La Trobe University

Abstract Protein quantisation using mass spectrometry is a recent, powerful platform for determining relative protein levels for thousands of proteins simultaneously. In recent years, we have witnessed rapid development in spectrometry technologies; however, the statistical analysis of raw tandem spectra as well as processed data remains a challenging task. In this talk, we will use biological studies to illustrate the statistical challenges associated with analysing data from such a platform and approaches for extracting biological patterns and information. My discussion will focus on two separate aspects. The pre-processing component will examine various preprocessing approaches and describe a new method for enhancing deterministic protein identification from identified peptide sequences. The second component will discuss issues associated with downstream analysis.

Seminar Convenor Dr Andriy Olenko

If you are interested in attending this seminar in our access grid room then please check to see if the grid is already booked at this time and let Robert Pearson know that you would like to attend.

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