entrez	symbol	description	locus	hprd	hgnc	mim	refpro	refdna	ensembl	type	dominant	recessive	duplicability	origin	degree	mirna	function	expression	chromosome	tstart	tend	type_of_screening	cancer_type
65985	AACS	acetoacetyl-CoA synthetase	12q24.31	12391	21298	614364	NP_076417	NM_023928	ENSP00000324842	candidate	0	0	0	Last Universal Common Ancestor	1	1	Cellular metabolism	73	chr12	125550131	125626772	WGS	liver
19	ABCA1	ATP-binding cassette, sub-family A (ABC1), member 1	9q31.1	02501	29	600046	NP_005493	NM_005502	ENSP00000363868	candidate	0	0	0	Last Universal Common Ancestor	58	6	Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	91	chr9	107546599	107665960	WES	colorectal
21	ABCA3	ATP-binding cassette, sub-family A (ABC1), member 3	16p13.3	03369	33	601615	NP_001080	NM_001089	ENSP00000301732	candidate	0	0	0	Last Universal Common Ancestor	2	1	-1	49	chr16	2326678	2376467	WES	breast
10347	ABCA7	ATP-binding cassette, sub-family A (ABC1), member 7	19p13.3	09255	37	605414	NP_061985	NM_019112;NM_033308	ENSP00000263094	candidate	0	0	0	Last Universal Common Ancestor	5	1	Cellular processes	69	chr19	1041361	1065421	WES	pancreas
8647	ABCB11	ATP-binding cassette, sub-family B (MDR/TAP), member 11	2q24	04436	42	603201	NP_003733	NM_003742	ENSP00000263817	candidate	0	0	0	Last Universal Common Ancestor	4	1	-1	21	chr2	169780135	169874635	WES,WGS	colorectal,breast
340273	ABCB5	ATP-binding cassette, sub-family B (MDR/TAP), member 5	7p21.1	-	46	611785	NP_001157465;NP_001157413;NP_848654;NP_001157414	NM_001163993;NM_001163941;NM_178559;NM_001163942	ENSP00000384881;ENSP00000406730;ENSP00000383899	candidate	0	0	0	Last Universal Common Ancestor	2	2	-1	-1	chr7	20662909	20795244	WGS	chronic lymphocytic leukemia
11194	ABCB8	ATP-binding cassette, sub-family B (MDR/TAP), member 8	7q36	10400	49	605464	NP_009119	NM_007188	ENSP00000351717	candidate	0	0	0	Last Universal Common Ancestor	7	0	-1	0	chr7	150725603	150742433	WES	breast
10057	ABCC5	ATP-binding cassette, sub-family C (CFTR/MRP), member 5	3q27	06898	56	605251	NP_005679;NP_001018881	NM_005688;NM_001023587	ENSP00000371934;ENSP00000333926	candidate	0	0	0	Last Universal Common Ancestor	5	1	-1	97	chr3	183639091	183732180	WES	pancreas
10060	ABCC9	ATP-binding cassette, sub-family C (CFTR/MRP), member 9	12p12.1	03258	60	601439	NP_064693;NP_005682	NM_020298;NM_020297;NM_005691	ENSP00000261201;ENSP00000261200	candidate	0	0	0	Last Universal Common Ancestor	200	1	Cell response to stimuli,Cellular processes	49	chr12	21958111	22089608	WES	endometrium,gastric
6059	ABCE1	ATP-binding cassette, sub-family E (OABP), member 1	4q31	03132	69	601213	NP_001035809;NP_002931	NM_001040876;NM_002940	ENSP00000296577	candidate	0	0	1	Last Universal Common Ancestor	13	3	Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription	95	chr4	146025565	146048722	WGS	prostate
55324	ABCF3	ATP-binding cassette, sub-family F (GCN20), member 3	3q27.1	12404	72	-	NP_060828	NM_018358	ENSP00000411471	candidate	0	0	0	Last Universal Common Ancestor	32	0	-1	93	chr3	183903996	183911483	WGS	lung
64240	ABCG5	ATP-binding cassette, sub-family G (WHITE), member 5	2p21	05678	13886	605459	NP_071881	NM_022436	ENSP00000260645	candidate	0	0	0	Last Universal Common Ancestor	4	0	Cell response to stimuli,Cellular processes,Multicellular activities	10	chr2	44040258	44065818	WGS	lymphoma
64241	ABCG8	ATP-binding cassette, sub-family G (WHITE), member 8	2p21	05679	13887	605460	NP_071882	NM_022437	ENSP00000272286	candidate	0	0	0	Last Universal Common Ancestor	9	4	-1	-1	chr2	44066193	44105049	WES	melanoma
10006	ABI1	abl-interactor 1	10p11.2	04336	11320	603050	NP_001171595;NP_005461;NP_001171592;NP_001171593;NP_001171587;NP_001171590;NP_001012770;NP_001171594;NP_001171596;NP_001012769;NP_001012768;NP_001171591	NM_001178124;NM_005470;NM_001178121;NM_001178122;NM_001178116;NM_001178119;NM_001012752;NM_001178123;NM_001178125;NM_001012751;NM_001012750;NM_001178120	ENSP00000365308;ENSP00000365309;ENSP00000279599;ENSP00000352114;ENSP00000365340;ENSP00000365336;ENSP00000365307;ENSP00000439646;ENSP00000440101;ENSP00000365312	known	1	0	0	Eukaryotes	71	0	Cell cycle,Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction	89	chr10	27037502	27149792	CGC	leukemia
51225	ABI3	ABI family, member 3	17q21.3	05900	29859	606363	NP_057512;NP_001128658	NM_016428;NM_001135186	ENSP00000406651;ENSP00000225941	candidate	0	0	0	Eukaryotes	31	0	Cell motility and interactions,Cellular metabolism,Cellular processes	-1	chr17	47288087	47300074	WES	head and neck squamous cell carcinoma
25890	ABI3BP	ABI family, member 3 (NESH) binding protein	3q12	09380	17265	606279	NP_056244	NM_015429	ENSP00000284322	candidate	0	0	0	Metazoans	5	0	-1	10	chr3	100469342	100712249	WGS	chronic lymphocytic leukemia
25	ABL1	c-abl oncogene 1, non-receptor tyrosine kinase	9q34.1	01809	76	189980	NP_005148;NP_009297	NM_005157;NM_007313	ENSP00000323315	known	1	0	0	Last Universal Common Ancestor	365	3	Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	100	chr9	133589707	133761067	CGC	leukemia
27	ABL2	v-abl Abelson murine leukemia viral oncogene homolog 2	1q25.2	01259	77	164690	NP_001129472;NP_005149;NP_001161708;NP_001161711;NP_009298;NP_001161709;NP_001161710;NP_001129473	NM_001136000;NM_005158;NM_001168236;NM_001168239;NM_007314;NM_001168237;NM_001168238;NM_001136001	ENSP00000375897;ENSP00000386152;ENSP00000427562	known	1	0	0	Last Universal Common Ancestor	40	5	Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction	57	chr1	179076856	179198532	CGC	leukemia
84448	ABLIM2	actin binding LIM protein family, member 2	4p16.1	-	19195	612544	NP_001123556;NP_001123560;NP_001123558;NP_001123557;NP_115808;NP_001123559;NP_001123555	NM_001130084;NM_001130088;NM_001130086;NM_001130085;NM_032432;NM_001130087;NM_001130083	ENSP00000441255;ENSP00000354887;ENSP00000389410	candidate	0	0	0	Eukaryotes	3	0	Cellular processes	-1	chr4	7968720	8108365	WES	pancreas
26	ABP1	amiloride binding protein 1 (amine oxidase (copper-containing))	7q34-q36	00088	80	104610	NP_001082	NM_001091	ENSP00000354193	candidate	0	0	0	Last Universal Common Ancestor	3	0	-1	53	chr7	150553559	150558294	WES	breast
34	ACADM	acyl-CoA dehydrogenase, C-4 to C-12 straight chain	1p31	08447	89	607008	NP_000007;NP_001120800	NM_000016;NR_022013;NM_001127328	ENSP00000359878	candidate	0	0	0	Last Universal Common Ancestor	11	4	Cellular metabolism,Cellular processes	93	chr1	76194074	76228445	WES	breast
176	ACAN	aggrecan	15q26.1	01123	319	155760	NP_001126;NP_037359	NM_001135;NM_013227	ENSP00000341615;ENSP00000387356	candidate	0	0	0	Last Universal Common Ancestor	18	0	Cell motility and interactions,Cellular metabolism,Development	62	chr15	89379438	89417709	WES	colorectal
9744	ACAP1	ArfGAP with coiled-coil, ankyrin repeat and PH domains 1	17p13.1	08474	16467	607763	NP_055531	NM_014716	ENSP00000158762	candidate	0	0	0	Eukaryotes	11	0	Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction	35	chr17	7240054	7254711	WES	breast
1636	ACE	angiotensin I converting enzyme (peptidyl-dipeptidase A) 1	17q23.3	00108	2707	106180	NP_000780;NP_001171528;NP_690043	NM_000789;NM_152831;NM_001178057;NM_152830	ENSP00000290866	candidate	0	0	0	Last Universal Common Ancestor	4	1	Cell cycle,Cell motility and interactions,Cellular metabolism,Cellular processes,Development,Multicellular activities,Regulation of intracellular processes and metabolism	23	chr17	61554456	61574724	WES	lymphoma
340485	ACER2	alkaline ceramidase 2	9p22.1	16512	23675	613492	NP_001010887	NM_001010887	-	candidate	0	0	1	Eukaryotes	0	0	Cellular metabolism	-1	chr9	19409083	19450631	WGS	chronic lymphocytic leukemia
22985	ACIN1	apoptotic chromatin condensation inducer 1	14q11.2	05191	17066	604562	NP_001158287;NP_001158286;NP_001158288;NP_001158289;NP_055792	NM_001164815;NM_001164814;NM_001164816;NM_001164817;NM_014977	ENSP00000451328;ENSP00000405677;ENSP00000345541;ENSP00000350073;ENSP00000262710	candidate	0	0	0	Eukaryotes	14	3	Cell cycle,Cellular processes,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction	62	chr14	23528360	23564495	WGS	prostate
81616	ACSBG2	acyl-CoA synthetase bubblegum family member 2	19p13.3	09824	24174	614363	NP_112186	NM_030924	ENSP00000252669	candidate	0	0	0	Last Universal Common Ancestor	1	0	Cellular metabolism,Development,Multicellular activities	43	chr19	6141555	6190665	WGS	prostate
2181	ACSL3	acyl-CoA synthetase long-chain family member 3	2q34-q35	03845	3570	602371	NP_976251;NP_004448	NM_203372;NM_004457	-	known	1	0	0	Last Universal Common Ancestor	13	4	Cellular metabolism	94	chr2	223773491	223806369	CGC	prostate
51703	ACSL5	acyl-CoA synthetase long-chain family member 5	10q25.1-q25.2	16139	16526	605677	NP_976313;NP_057318;NP_976314	NM_203379;NM_016234;NM_203380	ENSP00000348429;ENSP00000346680;ENSP00000376796	candidate	0	0	0	Last Universal Common Ancestor	2	6	Cellular metabolism	83	chr10	114136068	114187113	WES	colorectal
23305	ACSL6	acyl-CoA synthetase long-chain family member 6	5q31	09190	16496	604443	NP_001192177;NP_001192180;NP_001192179;NP_056071;NP_001192176;NP_001009185	NM_001205248;NM_001205251;NM_001205250;NM_015256;NM_001205247;NM_001009185	ENSP00000368566	known	1	0	0	Last Universal Common Ancestor	0	1	Cell cycle,Cellular metabolism,Development	93	chr5	131289930	131347246	CGC	leukemia
116285	ACSM1	acyl-CoA synthetase medium-chain family member 1	16p12.3	12551	18049	614357	NP_443188	NM_052956	ENSP00000301956	candidate	0	0	0	Last Universal Common Ancestor	0	1	Cellular metabolism	2	chr16	20634811	20702510	WES	pancreas
60	ACTB	actin, beta	7p22	00032	132	102630	NP_001092	NM_001101	ENSP00000349960	candidate	0	0	39	Last Universal Common Ancestor	146	2	Cell response to stimuli	109	chr7	5567382	5569288	WES	lymphoma
91	ACVR1B	activin A receptor, type IB	12q13	03193	172	601300	NP_064733;NP_064732;NP_004293	NM_020328;NM_020327;NM_004302	ENSP00000257963	candidate	0	0	0	Last Universal Common Ancestor	32	6	Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	100	chr12	52345528	52387891	HTMS,WES	breast,lung,ovarian,pancreas,prostate,colorectal (non-hypermutated)
92	ACVR2A	activin A receptor, type IIA	2q22.3	00025	173	102581	NP_001607	NM_001616	ENSP00000241416	candidate	0	0	0	Last Universal Common Ancestor	23	5	Cellular metabolism,Cellular processes,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction	95	chr2	148602722	148684840	WES	colorectal (hypermutated),gastric
102	ADAM10	ADAM metallopeptidase domain 10	15q2|15q22	03723	188	602192	NP_001101	NM_001110	-	candidate	0	0	0	Eukaryotes	4	2	Cell motility and interactions,Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction	65	chr15	58889749	59041733	WES	lymphoma
8038	ADAM12	ADAM metallopeptidase domain 12	10q26.3	04092	190	602714	NP_003465;NP_067673	NM_003474;NM_021641	ENSP00000357665	candidate	0	0	0	Last Universal Common Ancestor	32	4	Cell cycle,Cellular metabolism,Cellular processes,Development	60	chr10	127705851	128076714	WES	breast
8749	ADAM18	ADAM metallopeptidase domain 18	8p11.22	07469	196	-	NP_001177885;NP_055052	NM_001190956;NM_014237	ENSP00000429908;ENSP00000265707	candidate	0	0	0	Eukaryotes	39	1	Cellular metabolism,Development,Multicellular activities	27	chr8	39442142	39581427	WGS	prostate
8728	ADAM19	ADAM metallopeptidase domain 19	5q33.3	04704	197	603640	NP_150377	NM_023038;NM_033274	ENSP00000257527	candidate	0	0	0	Last Universal Common Ancestor	15	0	Cellular metabolism	77	chr5	156907960	157002704	WES	colorectal
2515	ADAM2	ADAM metallopeptidase domain 2	8p11.2	03322	198	601533	NP_001455	NM_001464	ENSP00000265708	candidate	0	0	0	Eukaryotes	4	1	Cellular metabolism,Cellular processes,Development	11	chr8	39603990	39695704	WES	chronic lymphocytic leukemia
53616	ADAM22	ADAM metallopeptidase domain 22	7q21	04751	201	603709	NP_057435;NP_068369;NP_068368;NP_004185;NP_068367	NM_016351;NM_021723;NM_021722;NM_004194;NM_021721	ENSP00000381260;ENSP00000381262;ENSP00000381267	candidate	0	0	0	Eukaryotes	9	0	Cell motility and interactions,Cellular metabolism,Development,Regulation of intracellular processes and metabolism	52	chr7	87563781	87822554	WGS	liver
11086	ADAM29	ADAM metallopeptidase domain 29	4q34	05306	207	604778	NP_001124176;NP_055084;NP_001124175;NP_001124177	NM_001130704;NM_014269;NM_001130703;NM_001130705	ENSP00000414544;ENSP00000384229;ENSP00000423517;ENSP00000352177	candidate	0	0	0	Eukaryotes	238	1	Cellular metabolism,Development,Multicellular activities	12	chr4	175896677	175899136	WES,WGS	colorectal,melanoma
8756	ADAM7	ADAM metallopeptidase domain 7	8p21.2	07391	214	607310	NP_003808	NM_003817	ENSP00000175238	candidate	0	0	0	Eukaryotes	3	0	Cellular metabolism	21	chr8	24298622	24365046	WES	melanoma
101	ADAM8	ADAM metallopeptidase domain 8	10q26.3	03777	215	602267	NP_001100;NP_001157962;NP_001157961	NM_001109;NM_001164490;NM_001164489	ENSP00000453302;ENSP00000453855;ENSP00000453043	candidate	0	0	0	Eukaryotes	2	1	Cellular metabolism	23	chr10	135076663	135089092	WGS	glioblastoma
9510	ADAMTS1	ADAM metallopeptidase with thrombospondin type 1 motif, 1	21q21.2	05530	217	605174	NP_008919	NM_006988	ENSP00000284984	candidate	0	0	0	Eukaryotes	24	5	Cell cycle,Cellular metabolism,Regulation of intracellular processes and metabolism,Signal transduction	81	chr21	28209901	28217273	WGS	lung
81794	ADAMTS10	ADAM metallopeptidase with thrombospondin type 1 motif, 10	19p13.2	07470	13201	608990	NP_112219	NM_030957	ENSP00000471851	candidate	0	0	0	Eukaryotes	10	0	Cellular metabolism,Signal transduction	-1	chr19	8645780	8670595	WGS	lymphoma
81792	ADAMTS12	ADAM metallopeptidase with thrombospondin type 1 motif, 12	5q35	05862	14605	606184	NP_112217	NM_030955	ENSP00000344847	candidate	0	0	0	Last Universal Common Ancestor	0	2	Cellular metabolism	71	chr5	33527296	33891961	WES	head and neck squamous cell carcinoma
11093	ADAMTS13	ADAM metallopeptidase with thrombospondin type 1 motif, 13	9q34	04994	1366	604134	NP_620595;NP_620596;NP_620594	NM_139028;NM_139026;NM_139027;NR_024514;NM_139025	ENSP00000360997;ENSP00000348997;ENSP00000347927	candidate	0	0	0	Eukaryotes	10	0	Cell motility and interactions,Cellular metabolism,Cellular processes,Multicellular activities,Signal transduction	21	chr9	136287564	136324299	WGS	melanoma
170692	ADAMTS18	ADAM metallopeptidase with thrombospondin type 1 motif, 18	16q23	06333	17110	607512	NP_955387	NM_139054;NM_199355	ENSP00000282849	candidate	0	0	0	Last Universal Common Ancestor	0	0	Cellular metabolism	-1	chr16	77317856	77468592	WES	colorectal
80070	ADAMTS20	ADAM metallopeptidase with thrombospondin type 1 motif, 20	12q12	-	17178	611681	NP_079279	NM_025003;NM_175851	ENSP00000374071	candidate	0	0	0	Last Universal Common Ancestor	1	0	Cellular metabolism	22	chr12	43748015	43945724	WES	colorectal,pancreas
57188	ADAMTSL3	ADAMTS-like 3	15q25.2	12426	14633	609199	NP_997400	NM_207517	ENSP00000286744	candidate	0	0	0	Eukaryotes	0	0	-1	65	chr15	84324514	84706555	WES	colorectal,lymphoma
105	ADARB2	adenosine deaminase, RNA-specific, B2	10p15.3	09070	227	602065	NP_061172	NM_018702	-	candidate	0	0	0	Eukaryotes	1	0	DNA/RNA metabolism and transcription,Regulation of transcription	27	chr10	1229136	1779344	WES	colorectal
107	ADCY1	adenylate cyclase 1 (brain)	7p13-p12	00053	232	103072	NP_066939	NM_021116	ENSP00000297323	candidate	0	0	0	Last Universal Common Ancestor	2	0	Cellular metabolism,DNA/RNA metabolism and transcription,Signal transduction	63	chr7	45614143	45753591	WES	lung
108	ADCY2	adenylate cyclase 2 (brain)	5p15.3	00052	233	103071	NP_065433	NM_020546	ENSP00000342952	candidate	0	0	0	Last Universal Common Ancestor	3	0	Cellular metabolism,DNA/RNA metabolism and transcription,Signal transduction	73	chr5	7396410	7826981	WGS	lung
109	ADCY3	adenylate cyclase 3	2p23.3	02620	234	600291	NP_004027	NM_004036	ENSP00000260600	candidate	0	0	0	Last Universal Common Ancestor	3	3	Cell cycle,Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Signal transduction	97	chr2	25042804	25141856	WGS	breast
114	ADCY8	adenylate cyclase 8 (brain)	8q24	00051	239	103070	NP_001106	NM_001115	ENSP00000367161	candidate	0	0	0	Last Universal Common Ancestor	4	0	Cellular metabolism,DNA/RNA metabolism and transcription,Signal transduction	9	chr8	131792639	132052579	WES,WGS	head and neck squamous cell carcinoma,lung
148	ADRA1A	adrenergic, alpha-1A-, receptor	8p21.2	00081	277	104221	NP_000671;NP_150647;NP_150646;NP_150645	NM_000680;NM_033304;NM_033303;NM_033302	ENSP00000276393;ENSP00000369956;ENSP00000369960;ENSP00000346557	candidate	0	0	0	Metazoans	12	0	Cell cycle,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction	60	chr8	26627783	26722486	WGS	melanoma
152	ADRA2C	adrenergic, alpha-2C-, receptor	4p16	00085	283	104250	NP_000674	NM_000683	ENSP00000386069	candidate	0	0	0	Metazoans	5	0	Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction	14	chr4	3768334	3769719	WGS	melanoma
4299	AFF1	AF4/FMR2 family, member 1	4q21	08871	7135	159557	NP_001160165;NP_005926	NM_001166693;NM_005935	ENSP00000378578;ENSP00000305689	known	1	0	0	Eukaryotes	30	1	-1	108	chr4	87967313	88056850	CGC	leukemia
2334	AFF2	AF4/FMR2 family, member 2	Xq28	02397	3776	300806	NP_001162594;NP_001162595;NP_001164099;NP_002016;NP_001162596;NP_001162593	NM_001169123;NM_001169124;NM_001170628;NM_002025;NM_001169125;NM_001169122	ENSP00000359486;ENSP00000286437;ENSP00000359489	candidate	0	0	0	Metazoans	4	0	Development	83	chrX	147582618	148072859	WES	breast
3899	AFF3	AF4/FMR2 family, member 3	2q11.2-q12	03272	6473	601464	NP_001020279;NP_002276	NM_001025108;NM_002285	ENSP00000348793;ENSP00000317421	known	1	0	0	Metazoans	1	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	4	chr2	100167939	100720916	CGC	leukemia
27125	AFF4	AF4/FMR2 family, member 4	5q31	09187	17869	604417	NP_055238	NM_014423	ENSP00000265343	known	1	0	0	Metazoans	27	8	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	25	chr5	132216754	132272881	CGC	leukemia
116986	AGAP2	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2	12q14.1	05687	16921	605476	NP_001116244;NP_055585	NM_001122772;NM_014770	ENSP00000257897	candidate	0	0	0	Eukaryotes	10	0	Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction	40	chr12	58120338	58132029	WES	breast
3267	AGFG1	ArfGAP with FG repeats 1	2q36.3	02918	5175	600862	NP_001128661;NP_004495;NP_001128659;NP_001128660	NM_001135189;NM_004504;NM_001135187;NM_001135188	-	candidate	0	0	0	Eukaryotes	14	4	Cellular processes,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction	103	chr2	228337138	228419208	WGS	melanoma
392636	AGMO	alkylglycerol monooxygenase	7p21.2	13362	33784	613738	NP_001004320	NM_001004320	ENSP00000341662	candidate	0	0	0	Last Universal Common Ancestor	0	0	-1	-1	chr7	15240913	15601470	WGS	liver
85007	AGXT2L2	alanine-glyoxylate aminotransferase 2-like 2	5q35.3	18482	28249	-	NP_699204	NM_153373;NM_032921	ENSP00000310978	candidate	0	0	0	Last Universal Common Ancestor	1	0	-1	-1	chr5	177638925	177659551	WGS	chronic lymphocytic leukemia
79026	AHNAK	AHNAK nucleoprotein	11q12.2	14684	347	103390	NP_001611;NP_076965	NM_001620;NM_024060	ENSP00000367263;ENSP00000257247	candidate	0	0	0	Last Universal Common Ancestor	29	2	Development	97	chr11	62284219	62303570	WES	kidney
113146	AHNAK2	AHNAK nucleoprotein 2	14q32.33	-	20125	608570	NP_612429	NM_138420	ENSP00000353114	candidate	0	0	0	Last Universal Common Ancestor	3	7	Development	49	chr14	105404403	105444574	WGS	melanoma
202	AIM1	absent in melanoma 1	6q21	18576	356	601797	NP_001615	NM_001624	ENSP00000358062	candidate	0	0	0	Last Universal Common Ancestor	2	5	-1	94	chr6	106960217	107016438	WES	breast
204	AK2	adenylate kinase 2	1p34	00047	362	103020	NP_001616;NP_037543;NP_001186128	NR_037592;NM_001625;NM_013411;NR_037591;NM_001199199	ENSP00000362548	candidate	0	0	1	Last Universal Common Ancestor	25	7	-1	107	chr1	33478785	33502429	WGS	chronic lymphocytic leukemia
11215	AKAP11	A kinase (PRKA) anchor protein 11	13q14.11	05261	369	604696	NP_057332	NM_016248;NM_144490	ENSP00000025301	candidate	0	0	0	Vertebrates	25	13	Signal transduction	103	chr13	42860485	42893361	WES	pancreas
9590	AKAP12	A kinase (PRKA) anchor protein 12	6q24-q25	05263	370	604698	NP_653080;NP_005091	NM_144497;NM_005100	ENSP00000384537	candidate	0	0	0	Last Universal Common Ancestor	10	4	Cellular processes,Signal transduction	92	chr6	151561698	151674872	WES	colorectal
11214	AKAP13	A kinase (PRKA) anchor protein 13	15q24-q25	05253	371	604686	NP_658913;NP_009131;NP_006729	NM_144767;NM_007200;NM_006738	ENSP00000378026	candidate	0	0	0	Eukaryotes	8	1	Signal transduction	102	chr15	86064659	86287905	WES,WGS	kidney,pancreas,liver
9472	AKAP6	A kinase (PRKA) anchor protein 6	14q12	05257	376	604691	NP_004265	NM_004274	ENSP00000280979	candidate	0	0	0	Eukaryotes	17	0	Cellular processes	86	chr14	32902700	33293976	WES	chronic lymphocytic leukemia,colorectal
10270	AKAP8	A kinase (PRKA) anchor protein 8	19p13.1	05258	378	604692	NP_005849	NM_005858	ENSP00000269701	candidate	0	0	0	Vertebrates	15	4	Cell cycle,DNA/RNA metabolism and transcription,Signal transduction	68	chr19	15465729	15487826	WES	lymphoma
10142	AKAP9	A kinase (PRKA) anchor protein (yotiao) 9	7q21-q22	04921	379	604001	NP_005742;NP_671714	NM_147171;NM_005751;NM_147185;NM_147166	ENSP00000348573	known	1	0	0	Last Universal Common Ancestor	39	2	Multicellular activities,Signal transduction	77	chr7	91570414	91737949	CGC,HTMS	thyroid,breast,lung,ovarian,pancreas,prostate
57016	AKR1B10	aldo-keto reductase family 1, member B10 (aldose reductase)	7q33	05271	382	604707	NP_064695	NM_020299	ENSP00000352584	candidate	0	0	2	Last Universal Common Ancestor	49	5	Cellular metabolism	40	chr7	134212664	134223770	WES	melanoma
207	AKT1	v-akt murine thymoma viral oncogene homolog 1	14q32.32|14q32.32	01261	391	164730	NP_001014432;NP_001014431;NP_005154	NM_001014432;NM_001014431;NM_005163	ENSP00000384293;ENSP00000270202;ENSP00000450688	known	1	0	2	Last Universal Common Ancestor	65	11	Cell cycle,Cell response to stimuli,Cellular metabolism,Cellular processes,Development,Immune system response,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	90	chr14	105236681	105258980	CGC,HTMS,WES	breast,colorectal,lung,ovarian,pancreas,prostate
208	AKT2	v-akt murine thymoma viral oncogene homolog 2	19q13.1-q13.2	01262	392	164731	NP_001229956;NP_001229957;NP_001617	NM_001243027;NM_001243028;NM_001626	ENSP00000375892	known	1	0	1	Last Universal Common Ancestor	20	5	Cellular metabolism,Cellular processes	21	chr19	40739782	40771174	CGC,WES,Amplified	ovarian,pancreas,breast
10000	AKT3	v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)	1q44	06441	393	611223	NP_001193658;NP_005456;NP_859029	NM_001206729;NM_005465;NM_181690	ENSP00000355498;ENSP00000336943	known	0	0	1	Last Universal Common Ancestor	5	8	Cellular metabolism,Cellular processes,Signal transduction	97	chr1	243668554	244006472	CGC,Amplified	
64400	AKTIP	AKT interacting protein	16q12.2	07467	16710	608483	NP_071921;NP_001012398	NM_022476;NM_001012398	ENSP00000378152	candidate	0	0	1	Eukaryotes	57	0	Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism	57	chr16	53526327	53534171	WGS	prostate
213	ALB	albumin	4q13.3	00062	399	103600	NP_000468	NM_000477	ENSP00000295897	candidate	0	0	0	Vertebrates	168	0	Cell cycle,Cell motility and interactions,Cell response to stimuli,Cellular processes,Development,Other,Regulation of intracellular processes and metabolism	35	chr4	74270045	74286012	WGS	liver
217	ALDH2	aldehyde dehydrogenase 2 family (mitochondrial)	12q24.2	00003	404	100650	NP_001191818;NP_000681	NM_001204889;NM_000690	ENSP00000261733;ENSP00000403349	known	1	0	1	Last Universal Common Ancestor	13	5	Signal transduction	102	chr12	112204787	112241786	CGC	leiomyoma
238	ALK	anaplastic lymphoma receptor tyrosine kinase	2p23	00104	427	105590	NP_004295	NM_004304	ENSP00000373700	known	1	0	0	Last Universal Common Ancestor	58	1	Cellular metabolism,Cellular processes,Development,Signal transduction	37	chr2	29416093	30143525	CGC,WES	lung,lymphoma,neuroblastoma,colorectal
55821	ALLC	allantoicase	2q35	10642	17377	612396	NP_060906	NM_018436;NM_199232	ENSP00000252505	candidate	0	0	0	Last Universal Common Ancestor	35	0	-1	17	chr2	3721665	3750150	WES	head and neck squamous cell carcinoma
7840	ALMS1	Alstrom syndrome 1	2p13	06023	428	606844	NP_055935	NM_015120	ENSP00000264448	candidate	0	0	0	Metazoans	3	3	Cell response to stimuli	102	chr2	73613033	73836736	WES	pancreas
239	ALOX12	arachidonate 12-lipoxygenase	17p13.1	01066	429	152391	NP_000688	NM_000697	ENSP00000251535	candidate	0	0	0	Last Universal Common Ancestor	13	0	Cell cycle,Cell motility and interactions,Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism	18	chr17	6899437	6913739	WES,WGS	myeloma
247	ALOX15B	arachidonate 15-lipoxygenase, type B	17p13.1	04739	434	603697	NP_001034219;NP_001132;NP_001034220	NM_001039130;NM_001141;NM_001039131	ENSP00000369520;ENSP00000369530	candidate	0	0	0	Last Universal Common Ancestor	1	0	Cell cycle,Cell motility and interactions,Cellular metabolism,Development,Regulation of intracellular processes and metabolism	52	chr17	7942474	7951880	WGS	prostate
57679	ALS2	amyotrophic lateral sclerosis 2 (juvenile)	2q33.1	05893	443	606352	NP_065970;NP_001129217	NM_020919;NM_001135745	ENSP00000429223;ENSP00000264276	candidate	0	0	0	Last Universal Common Ancestor	6	0	Cell cycle,Cell response to stimuli,Cellular processes,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction	-1	chr2	202568845	202632108	WGS	melanoma
259173	ALS2CL	ALS2 C-terminal like	3p21.31	10643	20605	612402	NP_001177636;NP_667340;NP_877576	NR_033815;NM_001190707;NM_147129;NM_182775	ENSP00000313670	candidate	0	0	0	Last Universal Common Ancestor	21	0	Cellular processes	64	chr3	46712477	46730930	WES	chronic lymphocytic leukemia
267	AMFR	autocrine motility factor receptor	16q21	09130	463	603243	NP_001135	NM_138958;NM_001144	ENSP00000290649	candidate	0	0	0	Eukaryotes	86	0	Cell response to stimuli,Cellular metabolism,Cellular processes,Signal transduction	75	chr16	56396824	56459239	WES	breast
273	AMPH	amphiphysin	7p14-p13	02687	471	600418	NP_647477;NP_001626	NM_139316;NM_001635	ENSP00000348602;ENSP00000317441	candidate	0	0	0	Eukaryotes	4	0	Cellular processes,Multicellular activities	59	chr7	38424422	38670951	WES	liver
284	ANGPT1	angiopoietin 1	8q23.1	03392	484	601667	NP_001137;NP_001186788	NM_001146;NM_139290;NM_001199859	ENSP00000428340;ENSP00000297450	candidate	0	0	0	Eukaryotes	4	0	Development,Signal transduction	87	chr8	108264086	108509786	WES	melanoma
287	ANK2	ankyrin 2, neuronal	4q25-q27	00110	493	106410	NP_001120965;NP_001139;NP_066187	NM_001127493;NM_001148;NM_020977	ENSP00000421067;ENSP00000349588	candidate	0	0	0	Last Universal Common Ancestor	25	2	Signal transduction	87	chr4	113970885	114294605	WES	bladder
288	ANK3	ankyrin 3, node of Ranvier (ankyrin G)	10q21	02715	494	600465	NP_001191333;NP_066267;NP_001140;NP_001191332	NM_001204404;NM_020987;NM_001149;NM_001204403	ENSP00000280772	candidate	0	0	0	Last Universal Common Ancestor	22	0	Cellular processes,Signal transduction	89	chr10	61802452	62149296	WES	bladder
348094	ANKDD1A	ankyrin repeat and death domain containing 1A	15q22.31	14178	28002	-	NP_874362	NM_182703	ENSP00000369579	candidate	0	0	0	Last Universal Common Ancestor	0	0	Signal transduction	-1	chr15	65207998	65242201	WGS	prostate
23141	ANKLE2	ankyrin repeat and LEM domain containing 2	12q24.33	-	29101	-	NP_055929	NM_015114	ENSP00000350686	candidate	0	0	0	Eukaryotes	5	2	-1	64	chr12	133303831	133338384	WES	lymphoma
728747	ANKRD20A4	ankyrin repeat domain 20 family, member A4	9q21.11	-	31982	-	NP_001092275;XP_003403870	NM_001098805;XM_003403822	ENSP00000349891	candidate	0	0	7	Last Universal Common Ancestor	0	0	-1	-1	chr9	69382093	69424173	WGS	glioblastoma
22852	ANKRD26	ankyrin repeat domain 26	10pter-q22.1	16491	29186	610855	NP_055730;NP_001242982	NM_014915;NM_001256053	ENSP00000365255	candidate	0	0	0	Last Universal Common Ancestor	3	0	-1	49	chr10	27294522	27389255	WGS	acute myeloid leukemia
375248	ANKRD36	ankyrin repeat domain 36	2q11.2	16492	24079	-	NP_001157787	NM_198555;NM_001164315	ENSP00000391950	candidate	0	0	2	Last Universal Common Ancestor	0	0	-1	15	chr2	97779477	97915382	WGS	liver
121601	ANO4	anoctamin 4	12q23.1	15527	23837	610111	NP_849148	NM_178826	ENSP00000376705	candidate	0	0	0	Eukaryotes	0	0	-1	-1	chr12	101295564	101520845	WES	head and neck squamous cell carcinoma
324	APC	adenomatous polyposis coli	5q21-q22	01439	583	611731	NP_001120982;NP_000029;NP_001120983	NM_001127510;NM_000038;NM_001127511	ENSP00000257430;ENSP00000427089	known	0	1	0	Last Universal Common Ancestor	104	8	Cell cycle,Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction	72	chr5	112090588	112179820	CGC,HTMS,WES	colorectal,desmoid,glioma,liver,other,pancreas,lung,breast,colorectal (hypermutated),colorectal (non-hypermutated),prostate
10297	APC2	adenomatosis polyposis coli 2	19p13.3	09802	24036	612034	NP_005874	NM_005883	ENSP00000233607	candidate	0	0	0	Eukaryotes	2	0	Signal transduction	44	chr19	1453001	1470209	WES	breast
187	APLNR	apelin receptor	11q12	02503	339	600052	NP_005152	NM_005161;NR_027991	-	candidate	0	0	0	Vertebrates	0	0	Signal transduction	40	chr11	57003339	57004478	HTMS	breast,lung,ovarian,pancreas,prostate
116519	APOA5	apolipoprotein A-V	11q23	06966	17288	606368	NP_001160070;NP_443200	NM_001166598;NM_052968	ENSP00000445002	candidate	0	0	0	Vertebrates	3	0	Cellular metabolism,Cellular processes,Development,Multicellular activities,Regulation of intracellular processes and metabolism	-1	chr11	116660847	116662414	WGS	melanoma
338	APOB	apolipoprotein B (including Ag(x) antigen)	2p24-p23	00133	603	107730	NP_000375	NM_000384	ENSP00000233242	candidate	0	0	0	Metazoans	34	0	Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism	50	chr2	21224605	21265346	WES	gastric
10930	APOBEC2	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 2	6p21	07268	605	604797	NP_006780	NM_006789	-	candidate	0	0	0	Vertebrates	6	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of transcription	49	chr6	41021087	41029607	WES	lymphoma
364	AQP7	aquaporin 7	9p13	04277	640	602974	NP_001161	NM_001170	ENSP00000297988	candidate	0	0	4	Last Universal Common Ancestor	0	0	Cellular processes,Multicellular activities	13	chr9	33385006	33395195	WGS	lymphoma
367	AR	androgen receptor	Xq12	02437	644	313700	NP_000035;NP_001011645	NM_000044;NM_001011645	ENSP00000363822	known	0	0	0	Last Universal Common Ancestor	245	5	Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	64	chrX	66764989	66943680	CGC,WES,Amplified	prostate
116984	ARAP2	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2	4p14	09439	16924	606645	NP_056045	NM_139182;NM_015230	ENSP00000302895	candidate	0	0	0	Eukaryotes	0	3	Regulation of intracellular processes and metabolism,Signal transduction	78	chr4	36069532	36231108	WGS	prostate
10564	ARFGEF2	ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)	20q13.13	09250	15853	605371	NP_006411	NM_006420	ENSP00000360985	candidate	0	0	1	Last Universal Common Ancestor	8	0	Cellular processes,Signal transduction	91	chr20	47538427	47649733	WES	breast
9938	ARHGAP25	Rho GTPase activating protein 25	2p13.3	09805	28951	610587	NP_001159748;NP_001007232;NP_055697;NP_001159749	NM_001166276;NM_001007231;NM_014882;NM_001166277	ENSP00000386911;ENSP00000386241;ENSP00000386863	candidate	0	0	0	Eukaryotes	0	0	Signal transduction	67	chr2	68962332	69053323	WES	breast
23092	ARHGAP26	Rho GTPase activating protein 26	5q31	05643	17073	605370	NP_055886;NP_001129080	NM_015071;NM_001135608	ENSP00000367243	known	1	0	0	Eukaryotes	2	0	Cellular processes,Development,Signal transduction	60	chr5	142150327	142602008	CGC	leukemia,myelodysplasia
79822	ARHGAP28	Rho GTPase activating protein 28	18p11.31	10961	25509	610592	NP_001010000	NM_001010000;NM_030672	ENSP00000392660	candidate	0	0	0	Eukaryotes	5	6	Signal transduction	26	chr18	6837348	6912150	WES	chronic lymphocytic leukemia
9639	ARHGEF10	Rho guanine nucleotide exchange factor (GEF) 10	8p23	09735	14103	608136	NP_055444	NM_014629	ENSP00000340297	candidate	0	0	0	Eukaryotes	2	4	Signal transduction	53	chr8	1806125	1905426	WES	colorectal
23365	ARHGEF12	Rho guanine nucleotide exchange factor (GEF) 12	11q23.3	09207	14193	604763	NP_056128;NP_001185594	NM_015313;NM_001198665	ENSP00000349056;ENSP00000380942	known	1	0	0	Eukaryotes	4	1	Signal transduction	97	chr11	120278445	120355215	CGC	leukemia
54848	ARHGEF38	Rho guanine nucleotide exchange factor (GEF) 38	4q24	08613	25968	-	NP_060170;NP_001229658	NM_017700;NM_001242729	ENSP00000416125;ENSP00000265154	candidate	0	0	0	Eukaryotes	0	0	Signal transduction	55	chr4	106473923	106599091	WGS	chronic lymphocytic leukemia
8289	ARID1A	AT rich interactive domain 1A (SWI-like)	1p35.3	04319	11110	603024	NP_624361;NP_006006	NM_018450;NM_139135;NM_006015	ENSP00000320485	known	0	1	0	Last Universal Common Ancestor	47	6	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	108	chr1	27022895	27107244	CGC,WES,WGS	kidney,ovarian,bladder,breast,gastric,liver,lymphoma,neuroblastoma,pancreas,prostate
57492	ARID1B	AT rich interactive domain 1B (SWI1-like)	6q25.1	10660	18040	-	NP_065783;NP_059989	NM_020732;NM_017519	ENSP00000055163	candidate	0	0	0	Last Universal Common Ancestor	29	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	-1	chr6	157099064	157529022	WES,WGS	breast,neuroblastoma,liver
196528	ARID2	AT rich interactive domain 2 (ARID, RFX-like)	12q12	16505	18037	609539	NP_689854	NM_152641	ENSP00000335044	known	0	1	0	Metazoans	22	3	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	-1	chr12	46123620	46298858	CGC,WES,WGS	liver,breast,pancreas
405	ARNT	aryl hydrocarbon receptor nuclear translocator	1q21	00524	700	126110	NP_001184254;NP_001659;NP_848514	NM_178426;NM_001197325;NM_001668;NM_178427	ENSP00000351407	known	1	0	0	Eukaryotes	50	1	Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	39	chr1	150784500	150830937	CGC	leukemia
9915	ARNT2	aryl-hydrocarbon receptor nuclear translocator 2	15q24	-	16876	606036	NP_055677	NM_014862	ENSP00000307479	candidate	0	0	0	Eukaryotes	4	1	Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	44	chr15	80743217	80886036	WES	glioblastoma
10552	ARPC1A	actin related protein 2/3 complex, subunit 1A, 41kDa	7q22.1	07252	703	604220	NP_006400;NP_001177925	NM_006409;NM_001190996	ENSP00000262942	known	0	0	3	Last Universal Common Ancestor	4	0	Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism	100	chr7	98930977	98963549	CGC,Amplified	
421	ARVCF	armadillo repeat gene deleted in velocardiofacial syndrome	22q11.21	03778	728	602269	NP_001661	NM_001670	ENSP00000263207	candidate	0	0	0	Eukaryotes	8	0	-1	64	chr22	19958754	19978317	WGS	liver
142685	ASB15	ankyrin repeat and SOCS box containing 15	7q31.31	10669	19767	-	NP_563616	NM_080928	ENSP00000275699	candidate	0	0	0	Last Universal Common Ancestor	0	0	Signal transduction	-1	chr7	123254557	123277032	WES	kidney
140462	ASB9	ankyrin repeat and SOCS box containing 9	-	06452	17184	-	NP_001162003;NP_001026909;NP_076992;NP_001162002	NM_001168531;NM_001031739;NM_024087;NM_001168530	ENSP00000369855;ENSP00000369850;ENSP00000438943;ENSP00000369852	candidate	0	0	1	Last Universal Common Ancestor	14	0	Signal transduction	56	chrX	15262631	15287996	WGS	melanoma
435	ASL	argininosuccinate lyase	7cen-q11.2	01948	746	608310	NP_001020115;NP_000039;NP_001020117;NP_001020114	NM_001024944;NM_000048;NM_001024946;NM_001024943	ENSP00000307188;ENSP00000370219	candidate	0	0	0	Last Universal Common Ancestor	7	0	Cell response to stimuli,Cellular metabolism,Cellular processes,Development	64	chr7	65546790	65557896	WES	breast,pancreas
79058	ASPSCR1	alveolar soft part sarcoma chromosome region, candidate 1	17q25.3	06947	13825	606236	NP_076988;NP_001238817	NR_045351;NM_024083;NM_001251888	ENSP00000306625;ENSP00000302176	known	1	0	0	Eukaryotes	12	0	-1	15	chr17	79935523	79974988	CGC	sarcoma
460	ASTN1	astrotactin 1	1q25.2	09019	773	600904	NP_996991;NP_004310	NM_207108;NM_004319	ENSP00000354536;ENSP00000395041	candidate	0	0	0	Vertebrates	1	1	Cell motility and interactions	43	chr1	176833423	177133812	WES	glioblastoma
171023	ASXL1	additional sex combs like 1 (Drosophila)	20q11	16516	18318	612990	NP_056153;NP_001158075	NM_015338;NM_001164603	ENSP00000364839	known	0	1	0	Metazoans	21	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	104	chr20	30946579	31025138	CGC,WES	leukemia,myelodysplasia,breast,chronic lymphocytic leukemia
84896	ATAD1	ATPase family, AAA domain containing 1	10q23.31	12499	25903	614452	NP_116199	NM_032810	ENSP00000339016	candidate	0	0	1	Last Universal Common Ancestor	6	2	-1	-1	chr10	89514447	89574356	WGS	glioblastoma
466	ATF1	activating transcription factor 1	12q13	00440	783	123803	NP_005162	NM_005171	ENSP00000262053	known	1	0	0	Last Universal Common Ancestor	2	2	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	34	chr12	51173929	51213559	CGC	histiocytoma,melanoma
80162	ATHL1	ATH1, acid trehalase-like 1 (yeast)	11p15.5	07999	26210	-	NP_079368	NM_025092	ENSP00000387185	candidate	0	0	0	Last Universal Common Ancestor	0	1	-1	32	chr11	289817	294746	WGS	liver
471	ATIC	5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase	2q35	03434	794	601731	NP_004035	NM_004044	ENSP00000236959	known	1	0	0	Last Universal Common Ancestor	32	0	Cellular metabolism,DNA/RNA metabolism and transcription,Development	107	chr2	216177220	216214375	CGC	lymphoma
472	ATM	ataxia telangiectasia mutated	11q22-q23	06347	795	607585	NP_000042	NM_000051;NM_138292;NM_138293	ENSP00000278616	known	0	1	0	Eukaryotes	124	10	Cell cycle,Cell response to stimuli,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Signal transduction	99	chr11	108098352	108236232	CGC,HTMS,WES,WGS	leukemia,lung,chronic lymphocytic leukemia,pancreas,prostate,liver
1822	ATN1	atrophin 1	12p13.31	06311	3033	607462	NP_001931;NP_001007027	NM_001940;NM_001007026	ENSP00000349076;ENSP00000379915	candidate	0	0	0	Eukaryotes	151	0	Development	60	chr12	7043339	7050715	WES	breast
57194	ATP10A	ATPase, class V, type 10A	15q11.2	05790	13542	605855	NP_077816	NM_024490	-	candidate	0	0	0	Last Universal Common Ancestor	0	1	Cellular processes,Development,Regulation of intracellular processes and metabolism	65	chr15	25924491	26108243	WES	pancreas
23250	ATP11A	ATPase, class VI, type 11A	13q34	12059	13552	605868	NP_115565;NP_056020	NM_032189;NM_015205	ENSP00000364796;ENSP00000364781	candidate	0	0	0	Last Universal Common Ancestor	1	0	Cellular processes	49	chr13	113344731	113536375	WES	colorectal
57130	ATP13A1	ATPase type 13A1	19p13.11	12501	24215	-	NP_065143	NM_020410	ENSP00000349877	candidate	0	0	0	Last Universal Common Ancestor	2	3	Cellular processes	99	chr19	19756234	19774475	WES	colorectal
344905	ATP13A5	ATPase type 13A5	3q29	18597	31789	-	NP_940907	NM_198505	ENSP00000341942	candidate	0	0	0	Last Universal Common Ancestor	0	0	Cellular processes	-1	chr3	192992834	193096514	WES	colorectal
488	ATP2A2	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2	12q24.11	00161	812	108740	NP_001672;NP_733765	NM_001681;NM_170665;NM_001135765	ENSP00000311186;ENSP00000378872	candidate	0	0	2	Last Universal Common Ancestor	33	4	Cellular processes,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction	108	chr12	110719595	110784272	WES	leukemia
9914	ATP2C2	ATPase, Ca++ transporting, type 2C, member 2	16q24.1	13812	29103	613082	NP_055676	NM_014861	ENSP00000262429	candidate	0	0	0	Last Universal Common Ancestor	2	0	Cellular processes	71	chr16	84402222	84497335	WES	lymphoma
495	ATP4A	ATPase, H+/K+ exchanging, alpha polypeptide	19q13.1	00668	819	137216	NP_000695	NM_000704	ENSP00000262623	candidate	0	0	0	Last Universal Common Ancestor	0	0	Cellular processes	29	chr19	36041734	36054429	WES	gastric
5205	ATP8B1	ATPase, aminophospholipid transporter, class I, type 8B, member 1	18q21-q22|18q21.31	03867	3706	602397	NP_005594	NM_005603	ENSP00000445359	candidate	0	0	0	Last Universal Common Ancestor	7	0	Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	93	chr18	55315723	55399039	WES	breast
545	ATR	ataxia telangiectasia and Rad3 related	3q22-q24	08369	882	601215	NP_001175	NM_001184	ENSP00000343741	candidate	0	0	0	Eukaryotes	93	0	Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	66	chr3	142168274	142297546	WGS	liver
26033	ATRNL1	attractin-like 1	10q26	12504	29063	612869	NP_997186	NM_207303	ENSP00000347152	candidate	0	0	0	Eukaryotes	1	1	-1	51	chr10	116853510	117704287	WGS	glioblastoma
546	ATRX	alpha thalassemia/mental retardation syndrome X-linked	Xq21.1	02069	886	300032	NP_000480;NP_612114	NM_000489;NM_138270;NM_138271	ENSP00000362441;ENSP00000378967	known	0	1	0	Last Universal Common Ancestor	32	2	Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	101	chrX	76763832	76972722	CGC,WES	glioblastoma,pancreas
92552	ATXN3L	ataxin 3-like	Xp22.2	-	24173	-	NP_001129467	NM_001135995	ENSP00000369996	candidate	0	0	0	Eukaryotes	7	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	30	chrX	13336989	13338053	HTMS	breast,lung,ovarian,pancreas,prostate
6790	AURKA	aurora kinase A	20q13	04352	11393	603072	NP_940836;NP_003591;NP_940838;NP_940839;NP_940835;NP_940837	NM_198434;NM_003600;NM_198436;NM_198437;NM_198433;NM_198435	ENSP00000216911;ENSP00000379245;ENSP00000379250;ENSP00000379249;ENSP00000321591;ENSP00000379251	known	0	0	1	Last Universal Common Ancestor	97	5	Cell cycle,Cellular metabolism,Cellular processes,Regulation of transcription,Signal transduction	43	chr20	54945217	54963253	CGC,Amplified	
60370	AVPI1	arginine vasopressin-induced 1	10q24.2	16530	30898	-	NP_068378	NM_021732	ENSP00000359660	candidate	0	0	0	Vertebrates	3	1	Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction	98	chr10	99437629	99439662	WGS	glioblastoma
8312	AXIN1	axin 1	16p13.3	04819	903	603816	NP_851393;NP_003493	NM_181050;NM_003502	ENSP00000262320;ENSP00000346935	candidate	0	0	0	Eukaryotes	83	1	Cell cycle,Development,Multicellular activities,Other,Regulation of intracellular processes and metabolism,Signal transduction	35	chr16	338125	397025	WES,WGS	liver
567	B2M	beta-2-microglobulin	15q21-q22.2	00189	914	109700	NP_004039	NM_004048	-	candidate	0	0	0	Vertebrates	26	1	Immune system response	109	chr15	45003745	45007898	WES	lymphoma,non-hodgkin lymphoma
135152	B3GAT2	beta-1,3-glucuronyltransferase 2 (glucuronosyltransferase S)	6q13	06325	922	607497	NP_542780	NM_080742	-	candidate	0	0	0	Eukaryotes	1	0	Cellular metabolism	-1	chr6	71571369	71666132	WGS	chronic lymphocytic leukemia
29086	BABAM1	BRISC and BRCA1 A complex member 1	19p13.11	13702	25008	612766	NP_054892;NP_001028721	NM_014173;NM_001033549	ENSP00000352408;ENSP00000471605	candidate	0	0	0	Eukaryotes	71	4	-1	88	chr19	17379616	17389854	WGS	acute myeloid leukemia,chronic lymphocytic leukemia
9530	BAG4	BCL2-associated athanogene 4	8p11.23	04861	940	603884	NP_001191807;NP_004865	NM_001204878;NM_004874	ENSP00000287322	known	0	0	1	Eukaryotes	42	1	Cell cycle,Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism	3	chr8	38034388	38068008	CGC,Amplified	
577	BAI3	brain-specific angiogenesis inhibitor 3	6q12	04064	945	602684	NP_001695	NM_001704	ENSP00000359630	candidate	0	0	0	Eukaryotes	1	1	Signal transduction	51	chr6	69348568	70098780	HTMS,WES,WGS	breast,lung,ovarian,pancreas,prostate,gastric,melanoma
8314	BAP1	BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)	3p21.31-p21.2	04366	950	603089	NP_004647	NM_004656	ENSP00000417132	known	0	1	0	Eukaryotes	56	5	Cell cycle,Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism	63	chr3	52436307	52443625	CGC,WES	breast,kidney,lung,melanoma
29994	BAZ2B	bromodomain adjacent to zinc finger domain, 2B	2q24.2	09295	963	605683	NP_038478	NM_013450	ENSP00000376534	candidate	0	0	0	Eukaryotes	13	1	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	77	chr2	160176779	160335230	WGS	liver
8915	BCL10	B-cell CLL/lymphoma 10	1p22	04625	989	603517	NP_003912	NM_003921	ENSP00000359612	known	1	0	0	Metazoans	99	3	Cell cycle,Cell response to stimuli,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Immune system response,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	59	chr1	85733313	85742035	CGC,WES	lymphoma,non-hodgkin lymphoma
53335	BCL11A	B-cell CLL/lymphoma 11A (zinc finger protein)	2p16.1	05949	13221	606557	NP_075044;NP_060484;NP_612569	NM_022893;NM_018014;NM_138553;NM_138559	ENSP00000349300;ENSP00000338774;ENSP00000352648	known	1	0	0	Eukaryotes	21	6	Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription	82	chr2	60687542	60780405	CGC,WES	leukemia,breast
64919	BCL11B	B-cell CLL/lymphoma 11B (zinc finger protein)	14q32.2	05950	13222	606558	NP_612808;NP_075049	NM_138576;NM_022898	ENSP00000280435;ENSP00000349723	known	1	0	0	Eukaryotes	21	8	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	66	chr14	99640491	99737555	CGC	leukemia
596	BCL2	B-cell CLL/lymphoma 2	18q21.33|18q21.3	01045	990	151430	NP_000648;NP_000624	NM_000657;NM_000633	ENSP00000404214	known	1	0	0	Metazoans	138	44	Cell cycle,Cell response to stimuli,Cellular processes,Development,Immune system response,Multicellular activities,Other,Regulation of intracellular processes and metabolism,Signal transduction	83	chr18	60795861	60985899	CGC,WES	leukemia,non-hodgkin lymphoma,lymphoma
10017	BCL2L10	BCL2-like 10 (apoptosis facilitator)	15q21	06071	993	606910	NP_065129	NM_020396	-	candidate	0	0	0	Mammals	40	0	Cell cycle,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction	6	chr15	52402048	52404923	WES	lymphoma
599	BCL2L2	BCL2-like 2	14q11.2-q12	03569	995	601931	NP_001186768;NP_004041	NM_001199839;NM_004050	ENSP00000250405	known	0	0	0	Metazoans	21	9	Cell cycle,Development,Multicellular activities,Regulation of intracellular processes and metabolism	93	chr14	23776977	23778171	CGC,Amplified	
602	BCL3	B-cell CLL/lymphoma 3	19q13.1-q13.2	00179	998	109560	NP_005169	NM_005178	ENSP00000164227	known	1	0	0	Last Universal Common Ancestor	55	1	Cell cycle,Cell motility and interactions,Cell response to stimuli,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Immune system response,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	66	chr19	45252048	45262869	CGC	leukemia
603	BCL5	B-cell CLL/lymphoma 5	17q22	-	1000	151441	-	-	-	known	1	0	-1	Last Universal Common Ancestor	0	0	-1	-1	-	0	0	CGC	leukemia
604	BCL6	B-cell CLL/lymphoma 6	3q27	00180	1001	109565	NP_001124317;NP_001128210;NP_001697	NM_001130845;NM_138931;NM_001134738;NM_001706	ENSP00000384371	known	1	0	0	Last Universal Common Ancestor	143	8	Cell cycle,Cell motility and interactions,Cell response to stimuli,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Immune system response,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	101	chr3	187440249	187451481	CGC,WES	leukemia,non-hodgkin lymphoma
605	BCL7A	B-cell CLL/lymphoma 7A	12q24.13	03243	1004	601406	NP_066273;NP_001019979	NM_020993;NM_001024808	-	known	1	0	0	Metazoans	2	2	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	48	chr12	122459998	122497066	CGC	non-hodgkin lymphoma
607	BCL9	B-cell CLL/lymphoma 9	1q21	04000	1008	602597	NP_004317	NM_004326	ENSP00000234739	known	1	0	0	Metazoans	8	3	Signal transduction	51	chr1	147083636	147096757	CGC,WES	leukemia,colorectal
9774	BCLAF1	BCL2-associated transcription factor 1	6q22-q23	16544	16863	612588	NP_001070908;NP_055554;NP_001070909	NM_001077440;NM_014739;NM_001077441	ENSP00000229446;ENSP00000435210	candidate	0	0	1	Metazoans	10	1	Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription	106	chr6	136582403	136601004	WES	lung
54880	BCOR	BCL6 corepressor	Xp11.4	06458	20893	300485	NP_001116856;NP_060215;NP_001116855;NP_001116857	NM_001123384;NM_017745;NM_001123383;NM_001130139;NM_001123385;NM_020926	ENSP00000345923;ENSP00000367716;ENSP00000367705;ENSP00000380512	known	0	1	0	Last Universal Common Ancestor	30	3	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	34	chrX	39911365	39937182	CGC,WES	leukemia,retinoblastoma,medulloblastoma,myelodysplasia
613	BCR	breakpoint cluster region	22q11|22q11.23	01044	1014	151410	NP_004318;NP_067585	NM_004327;NM_021574	ENSP00000303507	known	1	0	0	Eukaryotes	83	0	Cellular metabolism,Cellular processes,Signal transduction	82	chr22	23523148	23657706	CGC,WES	leukemia,lymphoma
633	BGN	biglycan	Xq28	02359	1044	301870	NP_001702	NM_001711	ENSP00000327336	candidate	0	0	0	Last Universal Common Ancestor	18	0	-1	94	chrX	152770090	152773900	WES	breast
329	BIRC2	baculoviral IAP repeat containing 2	11q22	03419	590	601712	NP_001157	NM_001166	ENSP00000227758;ENSP00000431723	known	0	0	0	Eukaryotes	31	4	Cell cycle,Development,Regulation of intracellular processes and metabolism,Signal transduction	107	chr11	102220586	102248911	CGC,Amplified	
330	BIRC3	baculoviral IAP repeat containing 3	11q22	03426	591	601721	NP_892007;NP_001156	NM_182962;NM_001165	ENSP00000432907	known	1	0	0	Eukaryotes	59	3	Cell cycle,Development,Regulation of intracellular processes and metabolism,Signal transduction	36	chr11	102195241	102207830	CGC	lymphoma
79444	BIRC7	baculoviral IAP repeat containing 7	20q13.3	05761	13702	605737	NP_647478;NP_071444	NM_139317;NM_022161	ENSP00000345213;ENSP00000217169	candidate	0	0	0	Eukaryotes	19	0	Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Signal transduction	31	chr20	61867449	61870954	HTMS	breast,lung,ovarian,pancreas,prostate
641	BLM	Bloom syndrome, RecQ helicase-like	15q26.1	05211	1058	604610	NP_000048	NM_000057	ENSP00000347232	known	0	1	0	Last Universal Common Ancestor	58	3	Cell cycle,Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Immune system response,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	65	chr15	91290623	91358506	CGC	
657	BMPR1A	bone morphogenetic protein receptor, type IA	10q22.3	03192	1076	601299	NP_004320	NM_004329	ENSP00000224764	known	0	1	2	Last Universal Common Ancestor	33	3	Cell cycle,Cellular metabolism,Cellular processes,Development,Other,Regulation of intracellular processes and metabolism,Signal transduction	78	chr10	88635776	88683473	CGC	
658	BMPR1B	bone morphogenetic protein receptor, type IB	4q22-q24	04457	1077	603248	NP_001194	NM_001203	ENSP00000426617	candidate	0	0	1	Last Universal Common Ancestor	69	2	Cellular metabolism,Cellular processes,Development,Immune system response,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction	18	chr4	96025576	96075821	WGS	chronic lymphocytic leukemia
2186	BPTF	bromodomain PHD finger transcription factor	17q24.3	03490	3581	601819	NP_872579;NP_004450	NM_182641;NM_004459	ENSP00000334351;ENSP00000307208	candidate	0	0	0	Eukaryotes	23	1	Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription	102	chr17	65821841	65978401	WGS	liver
673	BRAF	v-raf murine sarcoma viral oncogene homolog B1	7q34	01264	1097	164757	NP_004324	NM_004333	ENSP00000288602	known	1	0	1	Last Universal Common Ancestor	53	0	Cell cycle,Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction	25	chr7	140434400	140624503	CGC,HTMS,WES,WGS	cholangiocarcinoma,colorectal,lung,melanoma,ovarian,pilocytic astrocytoma,thyroid,breast,pancreas,prostate,chronic lymphocytic leukemia,colorectal (hypermutated)
672	BRCA1	breast cancer 1, early onset	17q21	00218	1100	113705	NP_009229;NP_009225;NP_009228;NP_009230;NP_009231	NM_007305;NM_007298;NM_007294;NM_007297;NM_007295;NM_007302;NM_007303;NM_007299;NM_007301;NR_027676;NM_007296;NM_007300;NM_007306	ENSP00000350283;ENSP00000418775;ENSP00000312236;ENSP00000417148;ENSP00000418960	known	0	1	0	Eukaryotes	311	11	Cell cycle,Cell response to stimuli,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	27	chr17	41197698	41276113	CGC,WES	ovarian,breast
675	BRCA2	breast cancer 2, early onset	13q12.3	02554	1101	600185	NP_000050	NM_000059	ENSP00000369497	known	0	1	0	Eukaryotes	75	6	Cell cycle,Cell response to stimuli,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	22	chr13	32890598	32972904	CGC,WES	breast,ovarian,pancreas
8019	BRD3	bromodomain containing 3	9q34	03327	1104	601541	NP_031397	NM_007371	ENSP00000305918	known	1	0	0	Eukaryotes	21	3	-1	107	chr9	136898715	136918599	CGC	lethal midline carcinoma
23476	BRD4	bromodomain containing 4	19p13.1	10574	13575	608749	NP_490597;NP_055114	NM_058243;NM_014299	ENSP00000360901;ENSP00000263377	known	1	0	0	Eukaryotes	68	1	-1	108	chr19	15349191	15383910	CGC	lethal midline carcinoma
10902	BRD8	bromodomain containing 8	5q31	04166	19874	602848	NP_006687;NP_001157798;NP_631938	NM_006696;NM_001164326;NM_183359;NM_139199	ENSP00000394330;ENSP00000230901;ENSP00000254900	candidate	0	0	0	Eukaryotes	10	3	Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	99	chr5	137475766	137513354	WGS	liver
9577	BRE	brain and reproductive organ-expressed (TNFRSF1A modulator)	2p23.2	08498	1106	610497	NP_954662;NP_954661;NP_954663;NP_004890;NP_954664	NM_199192;NM_199191;NM_199193;NM_004899;NM_199194	ENSP00000343412;ENSP00000368945;ENSP00000354699;ENSP00000368953;ENSP00000339371	candidate	0	0	0	Eukaryotes	54	3	Cell cycle,Development,Regulation of intracellular processes and metabolism,Signal transduction	100	chr2	28117424	28550297	WGS	liver
83990	BRIP1	BRCA1 interacting protein C-terminal helicase 1	17q22.2	05797	20473	605882	NP_114432	NM_032043	-	known	0	1	0	Last Universal Common Ancestor	11	3	Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	5	chr17	59760660	59938900	CGC	
84446	BRSK1	BR serine/threonine kinase 1	19q13.4	12533	18994	609235	NP_115806	NM_032430	ENSP00000310649	candidate	0	0	0	Last Universal Common Ancestor	7	0	Cell cycle,Cell response to stimuli,Cellular metabolism,Cellular processes,Development,Signal transduction	-1	chr19	55795811	55823433	WES	lymphoma
114781	BTBD9	BTB (POZ) domain containing 9	6p21	12543	21228	611237	NP_001165889;NP_689946;NP_001092742;NP_443125	NM_001172418;NM_152733;NM_001099272;NM_052893	ENSP00000418751;ENSP00000323408	candidate	0	0	0	Eukaryotes	9	1	-1	-1	chr6	38142764	38565870	WGS	melanoma
694	BTG1	B-cell translocation gene 1, anti-proliferative	12q22	15912	1130	109580	NP_001722	NM_001731	-	known	1	0	0	Eukaryotes	23	1	Cell cycle,Cell motility and interactions,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription	108	chr12	92537859	92539311	CGC,WES	leukemia,lymphoma,non-hodgkin lymphoma
7832	BTG2	BTG family, member 2	1q32	03357	1131	601597	NP_006754	NM_006763	ENSP00000290551	candidate	0	0	0	Eukaryotes	34	9	Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription	93	chr1	203274735	203276563	WES	non-hodgkin lymphoma
701	BUB1B	budding uninhibited by benzimidazoles 1 homolog beta (yeast)	15q15	04176	1149	602860	NP_001202	NM_001211	ENSP00000287598	known	0	1	0	Eukaryotes	61	3	Cell cycle,Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction	39	chr15	40457252	40512957	CGC	
414235	C10orf108	chromosome 10 open reading frame 108	10p15.3	18528	30724	-	-	NM_001012714;NR_027152;NR_027151	-	candidate	0	0	-1	Opisthokonts	0	0	-1	-1	-	0	0	WGS	chronic lymphocytic leukemia
26098	C10orf137	chromosome 10 open reading frame 137	10q26.13	10694	24640	-	NP_056423;NP_001189367	NM_030897;NM_015608;NM_001202438	ENSP00000349244;ENSP00000336727	candidate	0	0	0	Eukaryotes	69	4	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	74	chr10	127408377	127452038	WES	colorectal
56652	C10orf2	chromosome 10 open reading frame 2	10q24	05830	1160	606075	NP_001157286;NP_068602;NP_001157285;NP_001157284	NM_001163814;NM_021830;NM_001163813;NM_001163812	ENSP00000359248;ENSP00000309595	candidate	0	0	0	Last Universal Common Ancestor	10	4	Cellular metabolism,DNA/RNA metabolism and transcription	38	chr10	102747968	102753264	WES	leukemia
79946	C10orf95	chromosome 10 open reading frame 95	10q24.32	10701	25880	-	NP_079162	NM_024886	ENSP00000239125	candidate	0	0	0	Mammals	2	0	-1	3	chr10	104210217	104211225	WGS	liver
746	C11orf10	chromosome 11 open reading frame 10	11q12.2	12602	1164	-	NP_055021	NM_014206	ENSP00000257262	candidate	0	0	1	Metazoans	1	0	-1	109	chr11	61557270	61558074	WGS	breast
56946	C11orf30	chromosome 11 open reading frame 30	11q13.5	10544	18071	608574	NP_064578	NM_020193	ENSP00000334130	known	0	0	0	Eukaryotes	19	1	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	12	chr11	76157983	76261187	CGC,Amplified	
55196	C12orf35	chromosome 12 open reading frame 35	12p11.21	07691	25559	-	NP_060639	NM_018169	ENSP00000310338	candidate	0	0	0	Vertebrates	5	2	-1	88	chr12	32133890	32145466	WES	lymphoma
283450	C12orf51	chromosome 12 open reading frame 51	12q24.13	08170	26611	-	NP_001103132	NM_173813;NM_001109662	ENSP00000449784	candidate	0	0	0	Eukaryotes	1	1	Cellular metabolism,Cellular processes	80	chr12	112600194	112757291	WGS	liver
374467	C12orf63	chromosome 12 open reading frame 63	12q23.1	13484	24777	-	XP_003403698;XP_003118990	XM_003403650;NM_198520;XM_003118942	ENSP00000345466	candidate	0	0	0	Metazoans	1	0	-1	-1	chr12	97114186	97216599	WES	melanoma
93669	C12orf9	chromosome 12 open reading frame 9	-	-	15949	-	-	-	-	known	1	0	-1	-	0	0	-1	-1	-	0	0	CGC	lipoma
122046	C13orf26	chromosome 13 open reading frame 26	13q12.3	17551	28622	-	NP_689538	NM_152325	-	candidate	0	0	0	Metazoans	0	0	-1	-1	chr13	31506853	31549041	WGS	glioblastoma
55051	C14orf102	chromosome 14 open reading frame 102	14q32.11	12625	20186	-	NP_950244;NP_060440	NM_199043;NM_017970	ENSP00000350579	candidate	0	0	0	Eukaryotes	3	0	-1	2	chr14	90744683	90798248	WGS	lung
55195	C14orf105	chromosome 14 open reading frame 105	14q22.3	12628	20189	-	NP_060638	NM_018168	ENSP00000216445	candidate	0	0	0	Metazoans	0	0	-1	4	chr14	57938076	57960433	WGS	glioblastoma
80017	C14orf159	chromosome 14 open reading frame 159	14q32.11	16612	20498	-	NP_001095839;NP_001095836;NP_001095838;NP_001095837;NP_079228	NM_001102369;NM_001102366;NM_001102368;NM_001102367;NM_024952	ENSP00000428974;ENSP00000427953;ENSP00000256324;ENSP00000429453;ENSP00000404343	candidate	0	0	0	Last Universal Common Ancestor	1	1	-1	89	chr14	91626639	91691174	WGS	glioblastoma
317761	C14orf39	chromosome 14 open reading frame 39	14q23.1	08504	19849	-	NP_777638	NM_174978	ENSP00000324920	candidate	0	0	0	Vertebrates	0	1	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	-1	chr14	60903566	60951796	WGS	chronic lymphocytic leukemia
161176	C14orf49	chromosome 14 open reading frame 49	14q32.13	12652	19861	610861	NP_689805	NM_152592	ENSP00000334308	candidate	0	0	0	Eukaryotes	0	2	-1	-1	chr14	95884166	95942158	WES	prostate
23742	C15orf2	chromosome 15 open reading frame 2	15q11-q13	08506	1190	610922	NP_061831	NM_018958	ENSP00000333735	candidate	0	0	0	Mammals	0	0	Development,Multicellular activities	59	chr15	24921015	24924482	WES	colorectal
256646	C15orf55	chromosome 15 open reading frame 55	15q14	10606	29919	608963	NP_786883	NM_175741	ENSP00000329448	known	1	0	0	Vertebrates	45	1	-1	-1	chr15	34640169	34649689	CGC	lethal midline carcinoma
90416	C15orf57	chromosome 15 open reading frame 57	15q15.1	14473	28295	-	NP_443081;NP_001074261;NP_001074260	NM_052849;NM_001080792;NM_001080791	ENSP00000397515;ENSP00000350695	candidate	0	0	0	Metazoans	1	4	-1	-1	chr15	40846173	40855226	WGS	glioblastoma
201229	C17orf108	chromosome 17 open reading frame 108	17q11.2	-	27314	-	NP_001070148	NM_001076680	-	candidate	0	0	0	Metazoans	1	0	-1	59	chr17	26207300	26209720	WES	lung
753	C18orf1	chromosome 18 open reading frame 1	18p11.21	07358	1224	606571	NP_852146;NP_852148;NP_004329;NP_001003675;NP_852147;NP_001003674	NM_181481;NM_181483;NM_004338;NM_001003675;NM_181482;NM_001003674	ENSP00000382740;ENSP00000382741	candidate	0	0	0	Metazoans	1	4	-1	81	chr18	13438236	13645653	WGS	melanoma
374864	C18orf34	chromosome 18 open reading frame 34	18q12.1	12691	29588	-	NP_001098998;NP_945346	NM_001105528;NM_198995	ENSP00000385591;ENSP00000300227	candidate	0	0	0	Metazoans	0	0	-1	-1	chr18	30517978	30992052	WES	liver
255057	C19orf26	chromosome 19 open reading frame 26	19p13.3	16627	28617	-	NP_689982	NM_152769	ENSP00000215376	candidate	0	0	0	Vertebrates	0	0	-1	1	chr19	1230895	1236081	WES	head and neck squamous cell carcinoma
148345	C1orf127	chromosome 1 open reading frame 127	1p36.22	08780	26730	-	NP_001164225	NM_173507;NM_001170754	ENSP00000366203	candidate	0	0	0	Vertebrates	0	0	-1	-1	chr1	11007723	11036312	WGS	melanoma
199920	C1orf168	chromosome 1 open reading frame 168	1p32.2	14120	27295	-	NP_001004303	NM_001004303	ENSP00000345972	candidate	0	0	0	Vertebrates	2	2	-1	-1	chr1	57185847	57258476	WES	gastric
149563	C1orf64	chromosome 1 open reading frame 64	1p36.13	14492	28339	-	NP_849162	NM_178840	-	candidate	0	0	0	Mammals	1	0	-1	-1	chr1	16330799	16332838	WES	breast
165257	C1QL2	complement component 1, q subcomponent-like 2	2q14.2	12713	24181	614330	NP_872334	NM_182528	ENSP00000272520	candidate	0	0	0	Eukaryotes	0	0	Cellular processes	-1	chr2	119914381	119915845	WES	head and neck squamous cell carcinoma
140834	C20orf62	chromosome 20 open reading frame 62	20q13.12	18555	16195	-	NP_848571	NM_178476	-	candidate	0	0	-1	Primates	0	0	-1	-1	-	0	0	WGS	lung
26005	C2CD3	C2 calcium-dependent domain containing 3	11q13.4	16811	24564	-	NP_056346	NM_015531	ENSP00000323339	candidate	0	0	0	Eukaryotes	0	1	-1	68	chr11	73748521	73881837	WES	pancreas
80304	C2orf44	chromosome 2 open reading frame 44	2p23.3	07972	26157	-	NP_001135791;NP_079479	NM_001142319;NM_025203	ENSP00000385816;ENSP00000295148	known	1	0	0	Metazoans	25	2	-1	29	chr2	24253806	24262364	CGC	lung
389197	C4orf50	chromosome 4 open reading frame 50	4p16.2	13538	33766	-	XP_003119970;XP_003118572	NM_207405;XM_003119922;XM_003118524	ENSP00000317287	candidate	0	0	0	Mammals	0	0	-1	-1	chr4	5961105	5982065	WES	pancreas
65250	C5orf42	chromosome 5 open reading frame 42	5p13.2	07822	25801	-	NP_075561	NM_023073	ENSP00000389014	candidate	0	0	0	Metazoans	9	0	-1	2	chr5	37107707	37247800	WES	breast
79747	C6orf103	chromosome 6 open reading frame 103	6q24.3	-	21212	-	NP_078970	NM_024694	ENSP00000381036	candidate	0	0	0	Eukaryotes	1	2	Cellular metabolism	13	chr6	146920177	147136350	WGS	lung
221322	C6orf170	chromosome 6 open reading frame 170	6q22.31	12867	21485	-	NP_689943	NM_152730	ENSP00000275159	candidate	0	0	0	Metazoans	2	0	Regulation of intracellular processes and metabolism,Signal transduction	-1	chr6	121401920	121655576	WES	glioblastoma
79161	C7orf23	chromosome 7 open reading frame 23	7q21.12	12911	21707	-	NP_077291	NM_024315	ENSP00000257637	candidate	0	0	0	Eukaryotes	0	0	-1	100	chr7	86825955	86848819	WES	head and neck squamous cell carcinoma
56892	C8orf4	chromosome 8 open reading frame 4	8p11.2	09650	1357	607702	NP_064515	NM_020130	ENSP00000319914	known	0	0	0	Vertebrates	3	4	Cell cycle	29	chr8	40011052	40011369	CGC,Amplified	
254778	C8orf46	chromosome 8 open reading frame 46	8q13.1	14565	28498	-	NP_689978	NM_152765	ENSP00000302260	candidate	0	0	0	Vertebrates	0	2	-1	-1	chr8	67405884	67428308	WES	melanoma
777	CACNA1E	calcium channel, voltage-dependent, R type, alpha 1E subunit	1q25-q31	03006	1392	601013	NP_001192223;NP_000712;NP_001192222	NM_001205294;NM_000721;NM_001205293	ENSP00000434814	known	0	0	0	Last Universal Common Ancestor	4	0	Cellular processes,Multicellular activities	10	chr1	181452881	181767967	CGC,Amplified	
778	CACNA1F	calcium channel, voltage-dependent, L type, alpha 1F subunit	Xp11.23	02119	1393	300110	NP_005174	NM_005183	ENSP00000321618;ENSP00000365427;ENSP00000365441	candidate	0	0	0	Last Universal Common Ancestor	2	0	Cell cycle,Cell response to stimuli,Cellular processes,Development,Regulation of intracellular processes and metabolism	3	chrX	49061600	49088390	WES	breast
8912	CACNA1H	calcium channel, voltage-dependent, T type, alpha 1H subunit	16p13.3	07442	1395	607904	NP_001005407;NP_066921	NM_001005407;NM_021098	ENSP00000351401;ENSP00000334198	candidate	0	0	0	Last Universal Common Ancestor	9	0	Cell cycle,Cellular processes,Development,Multicellular activities	0	chr16	1203738	1270991	WES	glioblastoma
781	CACNA2D1	calcium channel, voltage-dependent, alpha 2/delta subunit 1	7q21-q22	00245	1399	114204	NP_000713	NM_000722	ENSP00000348589	candidate	0	0	0	Eukaryotes	3	4	Cellular processes	31	chr7	81579711	82072775	WES	pancreas
55799	CACNA2D3	calcium channel, voltage-dependent, alpha 2/delta subunit 3	3p21.1	05907	15460	606399	NP_060868	NM_018398	ENSP00000419101	candidate	0	0	0	Eukaryotes	1	0	Cellular processes	20	chr3	54156741	55108230	WES	colorectal
811	CALR	calreticulin	19p13.3-p13.2	00169	1455	109091	NP_004334	NM_004343	ENSP00000320866	candidate	0	0	0	Eukaryotes	81	8	Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	109	chr19	13049494	13054724	WES	lymphoma
23261	CAMTA1	calmodulin binding transcription activator 1	1p36.31-p36.23	16681	18806	611501	NP_001229630;NP_056030;NP_001182492	NM_001242701;NM_015215;NM_001195563;NR_038934	-	known	1	0	0	Eukaryotes	1	6	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	32	chr1	6845591	7812591	CGC,WES	epitheliod hemangioendothelioma,lymphoma
124583	CANT1	calcium activated nucleotidase 1	17q25.3	13003	19721	613165	NP_001153244;NP_620148;NP_001153245	NM_001159772;NM_138793;NM_001159773	ENSP00000376241;ENSP00000307674	known	1	0	0	Eukaryotes	1	4	Regulation of intracellular processes and metabolism,Signal transduction	94	chr17	76989635	76993704	CGC	prostate
29775	CARD10	caspase recruitment domain family, member 10	22q13.1	06233	16422	607209	NP_055365	NM_014550	ENSP00000251973	candidate	0	0	0	Eukaryotes	1	6	Cell cycle,Regulation of intracellular processes and metabolism,Signal transduction	47	chr22	37887200	37915207	WES	pancreas
84433	CARD11	caspase recruitment domain family, member 11	7p22	06234	16393	607210	NP_115791	NM_032415	ENSP00000380150	known	1	0	0	Eukaryotes	29	1	Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Immune system response,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	-1	chr7	2946275	2987422	CGC,WES	lymphoma,kidney,non-hodgkin lymphoma
84674	CARD6	caspase recruitment domain family, member 6	5p13.1	09871	16394	609986	NP_115976	NM_032587	ENSP00000254691	candidate	0	0	0	Mammals	6	0	Cell cycle	-1	chr5	40841485	40854545	WGS	melanoma
833	CARS	cysteinyl-tRNA synthetase	11p15.5	00464	1493	123859	NP_001742;NP_001181926;NP_644802;NP_001014437	NM_001751;NR_036542;NM_001194997;NM_139273;NM_001014438;NM_001014437	ENSP00000369897;ENSP00000380300;ENSP00000278224	known	1	0	0	Last Universal Common Ancestor	10	1	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of transcription	109	chr11	3022347	3069232	CGC	lymphoma
57082	CASC5	cancer susceptibility candidate 5	15q14	10634	24054	609173	NP_653091;NP_733468	NM_144508;NM_170589	ENSP00000382576;ENSP00000335463	known	1	0	0	Metazoans	19	3	Cell cycle,Development,Multicellular activities	10	chr15	40897309	40954383	CGC	leukemia
841	CASP8	caspase 8, apoptosis-related cysteine peptidase	2q33-q34	03459	1509	601763	NP_001073594;NP_203522;NP_001219;NP_203519;NP_203520;NP_001073593	NM_001080125;NM_033358;NM_001228;NM_033355;NM_033356;NM_033357;NM_001080124	ENSP00000264274;ENSP00000351273;ENSP00000325722;ENSP00000376087	candidate	0	0	0	Last Universal Common Ancestor	156	2	Cell cycle,Cellular metabolism,Development,Regulation of intracellular processes and metabolism,Signal transduction	60	chr2	202122955	202151314	WES	breast,colorectal (hypermutated),head and neck squamous cell carcinoma
79820	CATSPERB	cation channel, sperm-associated, beta	14q32.12	16613	20500	611169	NP_079040	NM_024764	ENSP00000256343	candidate	0	0	0	Metazoans	0	2	Development,Multicellular activities	22	chr14	92047236	92195823	WES	breast
863	CBFA2T3	core-binding factor, runt domain, alpha subunit 2; translocated to, 3	16q24	04847	1537	603870	NP_787127;NP_005178	NM_175931;NM_005187	ENSP00000268679;ENSP00000332122	known	1	0	0	Opisthokonts	9	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	55	chr16	88943387	89043215	CGC	leukemia
865	CBFB	core-binding factor, beta subunit	16q22.1	00418	1539	121360	NP_074036;NP_001746	NM_022845;NM_001755	ENSP00000290858;ENSP00000415151	known	1	0	0	Metazoans	31	7	Cellular metabolism,DNA/RNA metabolism and transcription	107	chr16	67063311	67132678	CGC,HTMS,WES	leukemia,breast,lung,ovarian,pancreas,prostate
867	CBL	Cas-Br-M (murine) ecotropic retroviral transforming sequence	11q23.3	01320	1541	165360	NP_005179	NM_005188	ENSP00000264033	known	1	1	0	Metazoans	269	0	Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction	26	chr11	119077128	119170488	CGC	leukemia,myelodysplasia
868	CBLB	Cas-Br-M (murine) ecotropic retroviral transforming sequence b	3q13.11	05136	1542	604491	NP_733762	NM_170662	ENSP00000377595	known	0	1	0	Metazoans	63	0	Cellular processes,Signal transduction	83	chr3	105377817	105586421	CGC	leukemia
23624	CBLC	Cas-Br-M (murine) ecotropic retroviral transforming sequence c	19q13.2	09765	15961	608453	NP_036248;NP_001124324	NM_012116;NM_001130852	ENSP00000340250;ENSP00000270279	known	0	1	0	Mammals	15	1	Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction	1	chr19	45281189	45303697	CGC,HTMS	leukemia,breast,lung,ovarian,pancreas,prostate
57545	CC2D2A	coiled-coil and C2 domain containing 2A	4p15.32	-	29253	612013	NP_001073991;NP_065836;NP_001158192	NM_001080522;NM_020785;NM_001164720	ENSP00000421809;ENSP00000424368;ENSP00000426109	candidate	0	0	0	Eukaryotes	1	3	-1	-1	chr4	15480335	15603045	WES	pancreas
150275	CCDC117	coiled-coil domain containing 117	22q12.1	08167	26599	-	NP_775781	NM_173510	ENSP00000249064	candidate	0	0	0	Vertebrates	3	0	-1	-1	chr22	29168838	29182311	WGS	breast
643677	CCDC168	coiled-coil domain containing 168	13q33.1	-	26851	-	NP_001139669	NM_001146197	-	candidate	0	0	0	-	2	0	-1	-1	chr13	103381804	103411282	WES	glioblastoma
51134	CCDC41	coiled-coil domain containing 41	12q22	14869	17966	-	NP_001035858;NP_057206	NM_001042399;NM_016122	ENSP00000344655;ENSP00000380911	candidate	0	0	0	Eukaryotes	0	5	-1	39	chr12	94702592	94806266	WES	pancreas
8030	CCDC6	coiled-coil domain containing 6	10q21	09064	18782	601985	NP_005427	NM_005436	ENSP00000263102	known	1	0	0	Eukaryotes	11	4	-1	80	chr10	61552678	61666182	CGC	dominant,leukemia,lung,thyroid
160762	CCDC63	coiled-coil domain containing 63	12q24.11	08765	26669	-	NP_689804	NM_152591	ENSP00000312399	candidate	0	0	0	Eukaryotes	0	0	-1	-1	chr12	111291209	111345277	WES	melanoma
114800	CCDC85A	coiled-coil domain containing 85A	2p16.1	-	29400	-	NP_001073902	NM_001080433	ENSP00000384040	candidate	0	0	0	Metazoans	5	0	-1	-1	chr2	56411760	56611487	WGS	breast
54908	CCDC99	coiled-coil domain containing 99	5q35.1	08623	26010	-	NP_060255	NM_017785	ENSP00000265295	candidate	0	0	0	Eukaryotes	8	3	-1	14	chr5	169015421	169031208	WGS	liver
886	CCKAR	cholecystokinin A receptor	4p15.1-p15.2	00322	1570	118444	NP_000721	NM_000730	ENSP00000295589	candidate	0	0	0	Metazoans	4	0	Cell cycle,Cell motility and interactions,Cell response to stimuli,Development,Regulation of intracellular processes and metabolism,Signal transduction	30	chr4	26483263	26491889	HTMS	breast,lung,ovarian,pancreas,prostate
887	CCKBR	cholecystokinin B receptor	11p15.4	00323	1571	118445	NP_795344	NM_176875	ENSP00000335544	candidate	0	0	0	Metazoans	12	2	Cell cycle,Cell response to stimuli,Regulation of intracellular processes and metabolism,Signal transduction	58	chr11	6281159	6292770	HTMS	breast,lung,ovarian,pancreas,prostate
57820	CCNB1IP1	cyclin B1 interacting protein 1, E3 ubiquitin protein ligase	14q11.2	07000	19437	608249	NP_878272;NP_878271;NP_067001;NP_878269	NM_182852;NM_182851;NM_021178;NM_182849	ENSP00000351810;ENSP00000337396;ENSP00000409896	known	1	0	2	Eukaryotes	8	1	-1	99	chr14	20779712	20784682	CGC	leiomyoma
595	CCND1	cyclin D1	11q13	01346	1582	168461	NP_444284	NM_053056	ENSP00000227507	known	1	0	0	Last Universal Common Ancestor	24	31	Cell cycle,Cell response to stimuli,Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction	73	chr11	69456082	69466047	CGC,WES,WGS,Amplified	breast,leukemia,lung,myeloma
894	CCND2	cyclin D2	12p13	00451	1583	123833	NP_001750	NM_001759	ENSP00000261254	known	1	0	1	Last Universal Common Ancestor	28	21	Cell cycle,Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction	105	chr12	4383207	4409172	CGC,WGS,Amplified	non-hodgkin lymphoma,chronic lymphocytic leukemia
896	CCND3	cyclin D3	6p21	00452	1585	123834	NP_001129597;NP_001129489;NP_001751;NP_001129598	NM_001136125;NM_001136017;NM_001760;NM_001136126	ENSP00000362079;ENSP00000397545;ENSP00000401595;ENSP00000362082	known	1	0	0	Last Universal Common Ancestor	55	4	Cell cycle,Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction	108	chr6	41903681	41909387	CGC,WES	myeloma,breast,leukemia,lymphoma,non-hodgkin lymphoma
898	CCNE1	cyclin E1	19q12	00455	1589	123837	NP_001229	NM_001238;NM_057182	ENSP00000262643	known	1	0	0	Last Universal Common Ancestor	74	13	Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	31	chr19	30303594	30314681	CGC,Amplified	ovarian
57018	CCNL1	cyclin L1	3q25.31	10814	20569	613384	NP_064703	NM_020307	-	candidate	0	0	0	Eukaryotes	9	7	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	101	chr3	156866033	156877883	WES	gastric
1232	CCR3	chemokine (C-C motif) receptor 3	3p21.3	03167	1604	601268	NP_847898;NP_001828;NP_847899;NP_001158152	NM_178328;NM_001837;NM_178329;NM_001164680	ENSP00000440097;ENSP00000441600;ENSP00000379271	candidate	0	0	0	Mammals	12	0	Cell motility and interactions,Cell response to stimuli,Immune system response,Regulation of intracellular processes and metabolism,Signal transduction	19	chr3	46305895	46307714	HTMS	breast,lung,ovarian,pancreas,prostate
1234	CCR5	chemokine (C-C motif) receptor 5 (gene/pseudogene)	3p21.31	03223	1606	601373	NP_000570;NP_001093638	NM_000579;NM_001100168	ENSP00000343985	candidate	0	0	1	Vertebrates	55	0	Cell motility and interactions,Cell response to stimuli,Immune system response,Other,Regulation of intracellular processes and metabolism,Signal transduction	1	chr3	46414394	46415449	HTMS	breast,lung,ovarian,pancreas,prostate
10693	CCT6B	chaperonin containing TCP1, subunit 6B (zeta 2)	17q12	09873	1621	610730	NP_001180459;NP_006575;NP_001180458	NM_001193530;NM_006584;NM_001193529	ENSP00000398044;ENSP00000400917;ENSP00000327191	candidate	0	0	2	Last Universal Common Ancestor	2	2	Cellular metabolism,Cellular processes,Development,Multicellular activities	51	chr17	33255070	33288412	WES	lymphoma
10694	CCT8	chaperonin containing TCP1, subunit 8 (theta)	21q22.11	10816	1623	-	NP_006576	NM_006585	ENSP00000286788	candidate	0	0	1	Last Universal Common Ancestor	27	0	Cellular metabolism,Cellular processes	108	chr21	30428799	30445911	WGS	prostate
135228	CD109	CD109 molecule	6q13	10590	21685	608859	NP_598000;NP_001153060;NP_001153059	NM_133493;NM_001159588;NM_001159587	ENSP00000388062;ENSP00000404475	candidate	0	0	0	Last Universal Common Ancestor	1	3	-1	-1	chr6	74405939	74533354	WES	colorectal
910	CD1B	CD1b molecule	1q22-q23	01775	1635	188360	NP_001755	NM_001764	ENSP00000357150	candidate	0	0	0	Mammals	4	0	-1	21	chr1	158298710	158301213	WGS	melanoma
913	CD1E	CD1e molecule	1q22-q23	01781	1638	188411	NP_001172039;NP_001036050;NP_001036049;NP_001036052;NP_001172043;NP_001172042;NP_001172037;NP_001036048;NP_001172036;NP_112155;NP_001172041;NP_001172044;NP_001036051	NM_001185110;NM_001042585;NM_001042584;NM_001042587;NM_001185114;NM_001185113;NM_001185108;NM_001042583;NM_001185107;NM_030893;NM_001185112;NM_001185115;NM_001042586	ENSP00000357142;ENSP00000357143;ENSP00000357145;ENSP00000357148;ENSP00000402906	candidate	0	0	0	Mammals	2	0	-1	24	chr1	158323779	158326683	WGS	prostate
29126	CD274	CD274 molecule	9p24	05655	17635	605402	NP_054862	NM_014143	ENSP00000370985;ENSP00000370989	known	1	0	0	Vertebrates	3	6	Cell cycle,Immune system response,Regulation of intracellular processes and metabolism,Signal transduction	-1	chr9	5456114	5466828	CGC	lymphoma
948	CD36	CD36 molecule (thrombospondin receptor)	7q11.2	01430	1663	173510	NP_001120915;NP_001001548;NP_001120916;NP_000063;NP_001001547	NM_001127443;NM_001001548;NM_001127444;NM_000072;NM_001001547	ENSP00000378268;ENSP00000308165;ENSP00000411411;ENSP00000392298	candidate	0	0	0	Eukaryotes	1	3	Cellular processes,Multicellular activities	54	chr7	80276057	80303460	WES	chronic lymphocytic leukemia,lymphoma
965	CD58	CD58 molecule	1p13	01081	1688	153420	NP_001138294;NP_001770	NR_026665;NM_001144822;NM_001779	ENSP00000409080;ENSP00000358501	candidate	0	0	0	Vertebrates	8	0	-1	57	chr1	117064526	117113594	WES	lymphoma,non-hodgkin lymphoma
923	CD6	CD6 molecule	11q13	01724	1691	186720	NP_001241680;NP_001241679;NP_006716	NM_001254751;NM_001254750;NR_045638;NM_006725	ENSP00000323280	candidate	0	0	0	Vertebrates	3	0	-1	67	chr11	60739338	60786787	WGS	lymphoma
970	CD70	CD70 molecule	19p13	18515	11937	602840	NP_001243	NM_001252	ENSP00000245903	candidate	0	0	0	Mammals	0	0	Cell cycle,Development,Regulation of intracellular processes and metabolism,Signal transduction	28	chr19	6586034	6591013	WES	lymphoma,non-hodgkin lymphoma
972	CD74	CD74 molecule, major histocompatibility complex, class II invariant chain	5q32	00825	1697	142790	NP_001020329;NP_001020330;NP_004346	NM_001025158;NM_001025159;NM_004355	ENSP00000367026;ENSP00000230685	known	1	0	0	Eukaryotes	20	0	Cell cycle,Cellular metabolism,Cellular processes,Development,Immune system response,Regulation of intracellular processes and metabolism,Signal transduction	104	chr5	149782127	149792312	CGC	lung
973	CD79A	CD79a molecule, immunoglobulin-associated alpha	19q13.2	00203	1698	112205	NP_067612;NP_001774	NM_021601;NM_001783	ENSP00000221972	known	1	0	0	Vertebrates	1	1	Cell response to stimuli,Development,Immune system response,Signal transduction	52	chr19	42381375	42385044	CGC	lymphoma
974	CD79B	CD79b molecule, immunoglobulin-associated beta	17q23	00922	1699	147245	NP_067613;NP_001035022;NP_000617	NM_021602;NM_001039933;NM_000626	ENSP00000006750;ENSP00000376544	known	1	0	0	Vertebrates	0	0	Signal transduction	31	chr17	62006589	62009621	CGC,WES	lymphoma,non-hodgkin lymphoma
925	CD8A	CD8a molecule	2p12	01737	1706	186910	NP_001759;NP_001139345;NP_741969	NM_001768;NR_027353;NM_001145873;NM_171827	ENSP00000386559;ENSP00000283635	candidate	0	0	0	Vertebrates	2	2	Immune system response,Signal transduction	66	chr2	87013046	87017948	WGS	chronic lymphocytic leukemia
22918	CD93	CD93 molecule	20p11.21	00396	15855	120577	NP_036204	NM_012072	ENSP00000246006	candidate	0	0	0	Eukaryotes	6	0	Cellular processes,Immune system response	92	chr20	23064898	23066829	WES	colorectal
995	CDC25C	cell division cycle 25 homolog C (S. pombe)	5q31	01146	1727	157680	NP_073720;NP_001781	NM_022809;NM_001790	ENSP00000321656;ENSP00000345205	candidate	0	0	0	Eukaryotes	42	1	Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Signal transduction	33	chr5	137621384	137666869	HTMS	breast,lung,ovarian,pancreas,prostate
996	CDC27	cell division cycle 27 homolog (S. cerevisiae)	17q21.32	00304	1728	116946	NP_001107563;NP_001247	NM_001114091;NM_001256	ENSP00000066544	candidate	0	0	2	Last Universal Common Ancestor	84	6	Cell cycle,Cellular metabolism,Regulation of intracellular processes and metabolism	92	chr17	45198304	45259006	WES,WGS	colorectal (hypermutated),lymphoma
998	CDC42	cell division cycle 42 (GTP binding protein, 25kDa)	1p36.1	00309	1736	116952	NP_001782;NP_426359;NP_001034891	NM_001791;NM_044472;NM_001039802	ENSP00000341072;ENSP00000383118;ENSP00000314458	candidate	0	0	10	Last Universal Common Ancestor	223	12	Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction	109	chr1	22404972	22418007	WGS	acute myeloid leukemia
9578	CDC42BPB	CDC42 binding protein kinase beta (DMPK-like)	14q32.3	08516	1738	614062	NP_006026	NM_006035	ENSP00000355237	candidate	0	0	0	Last Universal Common Ancestor	22	3	Cellular metabolism,Cellular processes,Development,Signal transduction	63	chr14	103400052	103523510	WES	pancreas
55561	CDC42BPG	CDC42 binding protein kinase gamma (DMPK-like)	11q13.1	13013	29829	613991	NP_059995	NM_017525	ENSP00000345133	candidate	0	0	0	Last Universal Common Ancestor	10	0	Cellular metabolism,Cellular processes,Signal transduction	-1	chr11	64591948	64612041	WES	pancreas
990	CDC6	cell division cycle 6 homolog (S. cerevisiae)	17q21.3	04022	1744	602627	NP_001245	NM_001254	ENSP00000209728	known	0	0	0	Last Universal Common Ancestor	46	3	Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	43	chr17	38445673	38458250	CGC,WGS,Amplified	breast
79577	CDC73	cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)	1q25	09581	16783	607393	NP_078805	NM_024529	ENSP00000356405	known	0	1	0	Eukaryotes	79	1	Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism	11	chr1	193091331	193219002	CGC	thyroid
999	CDH1	cadherin 1, type 1, E-cadherin (epithelial)	16q22.1	01885	1748	192090	NP_004351	NM_004360	ENSP00000261769	known	0	1	0	Last Universal Common Ancestor	125	7	Cell motility and interactions,Cellular processes,Regulation of intracellular processes and metabolism	55	chr16	68771319	68867399	CGC,HTMS,WES	breast,gastric,sarcoma
1008	CDH10	cadherin 10, type 2 (T2-cadherin)	5p14.2	05187	1749	604555	NP_006718	NM_006727;NM_001190450	ENSP00000264463	candidate	0	0	0	Eukaryotes	7	0	Cell motility and interactions	79	chr5	24487775	24593599	WES	head and neck squamous cell carcinoma,lung,pancreas
1009	CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)	16q21	08960	1750	600023	NP_001788	NM_001797	-	known	1	0	0	Eukaryotes	4	4	Cell motility and interactions,Development	82	chr16	64981509	65038772	CGC	bone cyst
1010	CDH12	cadherin 12, type 2 (N-cadherin 2)	5p14.3	11081	1751	600562	NP_004052	NM_004061	ENSP00000371689	candidate	0	0	0	Eukaryotes	3	3	Cell motility and interactions	20	chr5	21751849	22078785	WES	head and neck squamous cell carcinoma
28316	CDH20	cadherin 20, type 2	18q21.33	10429	1760	605807	NP_114097	NM_031891	ENSP00000444767	candidate	0	0	0	Eukaryotes	18	2	Cell motility and interactions	1	chr18	59157787	59221925	WES	breast
64072	CDH23	cadherin-related 23	10q22.1	05699	13733	605516	NP_001165406;NP_071407;NP_001165402;NP_443068;NP_001165405;NP_001165407;NP_001165403;NP_001165404;NP_001165401	NM_001171935;NM_022124;NM_001171931;NM_052836;NM_001171934;NM_001171936;NM_001171932;NM_001171933;NM_001171930	ENSP00000299366;ENSP00000381768;ENSP00000224721;ENSP00000381789	candidate	0	0	0	Last Universal Common Ancestor	3	0	Cell motility and interactions,Cell response to stimuli,Multicellular activities,Regulation of intracellular processes and metabolism	-1	chr10	73199589	73575032	WES	chronic lymphocytic leukemia
64403	CDH24	cadherin 24, type 2	14q11.2	13019	14265	-	NP_071923;NP_659422	NM_022478;NM_144985	ENSP00000380517;ENSP00000434821	candidate	0	0	0	Eukaryotes	4	0	Cell motility and interactions	-1	chr14	23517192	23524942	WGS	acute myeloid leukemia
1007	CDH9	cadherin 9, type 2 (T1-cadherin)	5p14	13021	1768	609974	NP_057363	NM_016279	ENSP00000231021	candidate	0	0	1	Eukaryotes	7	1	Cell motility and interactions	22	chr5	26881248	26988440	WES,WGS	chronic lymphocytic leukemia
54825	CDHR2	cadherin-related family member 2	5q35.2	15103	18231	-	NP_001165447;NP_060145	NM_001171976;NM_017675	ENSP00000424565;ENSP00000261944	candidate	0	0	0	Eukaryotes	5	1	Cell cycle,Cell motility and interactions,Regulation of intracellular processes and metabolism	66	chr5	175992354	176022670	WGS	acute myeloid leukemia
51755	CDK12	cyclin-dependent kinase 12	17q12	10849	24224	-	NP_055898;NP_057591	NM_015083;NM_016507	ENSP00000398880	known	0	1	0	Last Universal Common Ancestor	42	0	Cellular metabolism,Cellular processes	70	chr17	37618325	37687566	CGC,HTMS,WES	ovarian,breast,lung,pancreas,prostate
1019	CDK4	cyclin-dependent kinase 4	12q14	00447	1773	123829	NP_000066	NM_000075;NM_052984	-	known	1	0	0	Last Universal Common Ancestor	150	13	Cell cycle,Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Regulation of transcription	107	chr12	58142311	58145500	CGC,WES,Amplified	glioblastoma
1021	CDK6	cyclin-dependent kinase 6	7q21-q22	04533	1777	603368	NP_001138778;NP_001250	NM_001145306;NM_001259	ENSP00000265734	known	1	0	0	Last Universal Common Ancestor	108	28	Cell cycle,Cell motility and interactions,Cellular metabolism,Cellular processes,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription	5	chr7	92244457	92462637	CGC,Amplified	leukemia
1027	CDKN1B	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	12p13.1-p12	02867	1785	600778	NP_004055	NM_004064	ENSP00000228872	candidate	0	0	0	Metazoans	99	13	Cell cycle,Cell motility and interactions,Cell response to stimuli,Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction	103	chr12	12870774	12871877	WES	breast,prostate
1029	CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)	9p21	02542	1787	600160	NP_001182061;NP_478104;NP_478102;NP_000068	NM_058196;NM_001195132;NM_058197;NM_058195;NM_000077	ENSP00000307101;ENSP00000462950	known	0	1	0	Eukaryotes	177	13	Cell cycle,Cell motility and interactions,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Immune system response,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	51	chr9	21968727	21974826	CGC,HTMS,WES	melanoma,other,recessive,breast,lung,ovarian,pancreas,prostate,cholangiocarcinoma,glioblastoma,head and neck squamous cell carcinoma,liver
1031	CDKN2C	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)	1p32	04534	1789	603369	NP_001253;NP_523240	NM_001262;NM_078626	ENSP00000379452;ENSP00000360826	known	0	1	0	Last Universal Common Ancestor	35	1	Cell cycle,Cellular metabolism,Development,Regulation of intracellular processes and metabolism,Signal transduction	62	chr1	51436041	51439939	CGC	glioma,myeloma
1045	CDX2	caudal type homeobox 2	13q12.3	02622	1806	600297	NP_001256	NM_001265	-	known	1	0	0	Eukaryotes	16	10	Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription	0	chr13	28537255	28543143	CGC	leukemia
9425	CDYL	chromodomain protein, Y-like	6p25.1	04803	1811	603778	NP_001137442;NP_004815;NP_001137443	NM_001143970;NM_170752;NM_004824;NR_026590;NM_001143971	ENSP00000340908;ENSP00000330512	candidate	0	0	1	Last Universal Common Ancestor	27	0	Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription	24	chr6	4891947	4954287	WES	lung
1050	CEBPA	CCAAT/enhancer binding protein (C/EBP), alpha	19q13.1	00296	1833	116897	NP_004355	NM_004364	ENSP00000427514	known	1	0	0	-	96	7	Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	69	chr19	33792247	33793320	CGC	leukemia,myelodysplasia
10136	CELA3A	chymotrypsin-like elastase family, member 3A	1p36.12	06497	15944	-	NP_005738	NM_005747	ENSP00000290122	candidate	0	0	1	Last Universal Common Ancestor	0	0	Cellular metabolism	55	chr1	22328168	22336350	WGS	chronic lymphocytic leukemia
56853	CELF4	CUGBP, Elav-like family member 4	18q12	12534	14015	612679	NP_064565;NP_001020258;NP_001020260;NP_001020259	NM_020180;NM_001025087;NM_001025089;NM_001025088	ENSP00000406823;ENSP00000410584;ENSP00000335631	candidate	0	0	0	Eukaryotes	2	1	Cell cycle,Development	-1	chr18	34833777	35145604	WES	chronic lymphocytic leukemia
22995	CEP152	centrosomal protein 152kDa	15q21.1	16778	29298	613529	NP_001181927;NP_055800	NM_001194998;NM_014985	ENSP00000370337;ENSP00000382271	candidate	0	0	0	Metazoans	2	1	-1	23	chr15	49030449	49097846	WGS	lung
9859	CEP170	centrosomal protein 170kDa	1q44	17172	28920	613023	NP_001035864;NP_001035863;NP_055627	NM_001042405;NM_001042404;NM_014812	ENSP00000355502;ENSP00000355501;ENSP00000355500	candidate	0	0	1	Eukaryotes	19	0	-1	91	chr1	243289754	243388582	WGS	acute myeloid leukemia,chronic lymphocytic leukemia,prostate
3080	CFHR2	complement factor H-related 2	1q31.3	02933	4890	600889	NP_005657	NM_005666	ENSP00000356385	candidate	0	0	1	Vertebrates	0	1	-1	83	chr1	196913011	196928207	WES	melanoma
5199	CFP	complement factor properdin	Xp11.4	02308	8864	300383	NP_001138724;NP_002612	NM_001145252;NM_002621	ENSP00000380189;ENSP00000247153	candidate	0	0	0	Eukaryotes	4	1	Cell response to stimuli,Cellular metabolism,Immune system response	6	chrX	47483677	47489243	WES	breast
79145	CHCHD7	coiled-coil-helix-coiled-coil-helix domain containing 7	8q12.1	13048	28314	611238	NP_077276;NP_001011669;NP_001011670;NP_001011668;NP_001011667;NP_001011671	NM_024300;NM_001011669;NM_001011670;NM_001011668;NM_001011667;NM_001011671	ENSP00000306425;ENSP00000428274;ENSP00000347469;ENSP00000428917	known	1	0	0	Eukaryotes	0	3	-1	38	chr8	57125410	57129991	CGC	salivary
1105	CHD1	chromodomain helicase DNA binding protein 1	5q15-q21	03668	1915	602118	NP_001261	NM_001270	ENSP00000284049	candidate	0	0	0	Last Universal Common Ancestor	22	4	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	67	chr5	98192087	98262090	WGS	prostate
9557	CHD1L	chromodomain helicase DNA binding protein 1-like	1q12	09880	1916	613039	NP_004275;NP_078844;NP_001243266;NP_001243265;NP_001243267	NM_004284;NM_024568;NM_001256337;NR_046070;NM_001256336;NM_001256338	ENSP00000355100;ENSP00000358263;ENSP00000358262	known	0	0	0	Last Universal Common Ancestor	36	0	-1	109	chr1	146714354	146767187	CGC,Amplified	
1106	CHD2	chromodomain helicase DNA binding protein 2	15q26	03669	1917	602119	NP_001262;NP_001036037	NM_001271;NM_001042572	ENSP00000406581;ENSP00000377747	candidate	0	0	0	Last Universal Common Ancestor	4	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	49	chr15	93444468	93567932	WES	chronic lymphocytic leukemia
1107	CHD3	chromodomain helicase DNA binding protein 3	17p13.1	09071	1918	602120	NP_001005273;NP_001005271;NP_005843	NM_001005273;NM_001005271;NM_005852	ENSP00000369716;ENSP00000332628;ENSP00000350907	candidate	0	0	0	Last Universal Common Ancestor	188	1	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	78	chr17	7788125	7814900	WGS	breast
1108	CHD4	chromodomain helicase DNA binding protein 4	12p13	04472	1919	603277	NP_001264	NM_001273	ENSP00000349508	candidate	0	0	0	Last Universal Common Ancestor	94	4	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	109	chr12	6680032	6715539	WES	endometrium
450091	CHD5	Coronary heart disease, susceptibility to, 5	-	-	-	608901	-	-	-	candidate	0	0	-1	Last Universal Common Ancestor	0	0	-1	-1	-	0	0	WES,WGS	breast,prostate
84181	CHD6	chromodomain helicase DNA binding protein 6	20q12	13049	19057	-	NP_115597	NM_032221	ENSP00000362330	candidate	0	0	0	Last Universal Common Ancestor	11	1	Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription	-1	chr20	40033236	40162212	WES	bladder
55636	CHD7	chromodomain helicase DNA binding protein 7	8q12.2	10595	20626	608892	NP_060250	NM_017780	ENSP00000392028	candidate	0	0	0	Last Universal Common Ancestor	34	3	Cell cycle,Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription	86	chr8	61653992	61778489	WGS	medulloblastoma
11200	CHEK2	checkpoint kinase 2	22q11|22q12.1	05084	16627	604373	NP_001005735;NP_009125;NP_665861	NM_001005735;NM_007194;NM_145862	ENSP00000372023;ENSP00000329178;ENSP00000329012	known	0	1	0	Last Universal Common Ancestor	70	0	Cell cycle,Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction	35	chr22	29083888	29130709	CGC	
1113	CHGA	chromogranin A (parathyroid secretory protein 1)	14q32	07170	1929	118910	NP_001266	NM_001275	ENSP00000216492	candidate	0	0	0	Opisthokonts	7	0	Multicellular activities	59	chr14	93389705	93401226	WES	melanoma
1114	CHGB	chromogranin B (secretogranin 1)	20pter-p12	07512	1930	118920	NP_001810	NM_001819	ENSP00000368244	candidate	0	0	0	Metazoans	40	1	-1	65	chr20	5892280	5905692	WGS	breast
26511	CHIC2	cysteine-rich hydrophobic domain 2	4q11	10373	1935	604332	NP_036242	NM_012110	ENSP00000263921	known	1	0	0	Metazoans	9	4	-1	77	chr4	54876265	54930467	CGC	leukemia
10752	CHL1	cell adhesion molecule with homology to L1CAM (close homolog of L1)	3p26.1	07598	1939	607416	NP_001240317;NP_001240316;NP_006605	NM_001253388;NM_001253387;NR_045572;NM_006614	ENSP00000256509	candidate	0	0	0	Last Universal Common Ancestor	4	5	Cell cycle,Cell motility and interactions,Development,Signal transduction	43	chr3	361460	447391	WES	colorectal
25978	CHMP2B	charged multivesicular body protein 2B	3p11.2	13174	24537	609512	NP_001231573;NP_054762	NM_001244644;NM_014043	ENSP00000263780	candidate	0	0	0	Eukaryotes	18	3	Cellular processes	88	chr3	87289848	87302969	WES	melanoma
29082	CHMP4A	charged multivesicular body protein 4A	14q12	16597	20274	610051	NP_054888	NM_014169	ENSP00000324205	candidate	0	0	0	Eukaryotes	24	0	Cellular processes	73	chr14	24679086	24682774	WGS	glioblastoma
1123	CHN1	chimerin (chimaerin) 1	2q31.1	00319	1943	118423	NP_001020372;NP_001813;NP_001193531	NM_001025201;NM_001822;NM_001206602;NR_038133	ENSP00000295497;ENSP00000386741	known	1	0	0	Eukaryotes	12	0	Signal transduction	39	chr2	175664847	175809669	CGC	sarcoma
55584	CHRNA9	cholinergic receptor, nicotinic, alpha 9	4p14	16092	14079	605116	NP_060051	NM_017581	ENSP00000312663	candidate	0	0	0	Metazoans	0	1	Cellular processes	51	chr4	40337485	40356534	WGS	breast
8534	CHST1	carbohydrate (keratan sulfate Gal-6) sulfotransferase 1	11p11.2	07051	1969	603797	NP_003645	NM_003654	-	candidate	0	0	0	Metazoans	27	0	Cellular metabolism,Immune system response	68	chr11	45671241	45672473	WES	melanoma
56548	CHST7	carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7	Xp11.23	02302	13817	300375	NP_063939	NM_019886	ENSP00000276055	candidate	0	0	0	Vertebrates	1	1	Cellular metabolism	3	chrX	46433367	46434824	WGS	breast
23152	CIC	capicua homolog (Drosophila)	19q13.2	10831	14214	612082	NP_055940	NM_015125	ENSP00000160740	known	0	1	0	Last Universal Common Ancestor	25	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	91	chr19	42788857	42799340	CGC,WES	oligodendroglioma,breast
4261	CIITA	class II, major histocompatibility complex, transactivator	16p13	02475	7067	600005	NP_000237	NM_000246	-	known	1	0	0	Last Universal Common Ancestor	26	1	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	48	chr16	10971188	11017157	CGC,WES	lymphoma,non-hodgkin lymphoma
11113	CIT	citron (rho-interacting, serine/threonine kinase 21)	12q24	09289	1985	605629	NP_001193928;NP_009105	NM_001206999;NM_007174	ENSP00000376306;ENSP00000261833	candidate	0	0	0	Last Universal Common Ancestor	1	2	Cell cycle,Cellular metabolism,Cellular processes,Development,Signal transduction	80	chr12	120127953	120313972	WES	lung
1163	CKS1B	CDC28 protein kinase regulatory subunit 1B	1q21.2	00299	19083	116900	NP_001817	NM_001826;NR_024163	ENSP00000311083	known	0	0	8	Eukaryotes	30	0	Cell cycle,Regulation of intracellular processes and metabolism,Signal transduction	88	chr5	61808073	61808309	CGC,Amplified	
23155	CLCC1	chloride channel CLIC-like 1	1p13.3	17471	29675	-	NP_055942;NP_001041675	NM_015127;NM_001048210	ENSP00000358988;ENSP00000411591	candidate	0	0	0	Metazoans	2	0	-1	86	chr1	109477295	109493059	WGS	liver
1182	CLCN3	chloride channel 3	4q33	02785	2021	600580	NP_001820;NP_001230303;NP_776297;NP_001230301	NM_001829;NM_001243374;NM_173872;NM_001243372	ENSP00000424603	candidate	0	0	0	Last Universal Common Ancestor	5	4	Cellular processes,Regulation of intracellular processes and metabolism	103	chr4	170557080	170641213	WES	breast
1183	CLCN4	chloride channel 4	Xp22.3	02362	2022	302910	NP_001821	NM_001830	ENSP00000370213	candidate	0	0	2	Last Universal Common Ancestor	0	0	Cellular processes	49	chrX	10153073	10201621	WES	pancreas
1184	CLCN5	chloride channel 5	Xp11.23-p11.22	02053	2023	300008	NP_000075;NP_001121371;NP_001121370	NM_000084;NM_001127899;NM_001127898	ENSP00000365256	candidate	0	0	2	Last Universal Common Ancestor	0	1	Cellular processes	63	chrX	49806924	49856873	WGS	prostate
9076	CLDN1	claudin 1	3q28-q29	04760	2032	603718	NP_066924	NM_021101	ENSP00000295522	candidate	0	0	0	Vertebrates	17	3	Cell motility and interactions	32	chr3	190026069	190039995	WGS	lung
7122	CLDN5	claudin 5	22q11.21	03654	2047	602101	NP_003268;NP_001124333	NM_003277;NM_001130861	ENSP00000384554;ENSP00000400612	candidate	0	0	0	Vertebrates	18	2	Cell motility and interactions	64	chr22	19511125	19512033	WGS	glioblastoma
728276	CLEC19A	C-type lectin domain family 19, member A	16p12.3	-	34522	-	-	NR_024436	-	candidate	0	0	-1	Eukaryotes	0	0	-1	-1	-	0	0	WES	breast
6249	CLIP1	CAP-GLY domain containing linker protein 1	12q24.3	01568	10461	179838	NP_001234926;NP_937883;NP_002947	NM_001247997;NM_198240;NM_002956	ENSP00000351665;ENSP00000445531	candidate	0	0	0	Eukaryotes	8	5	Cell cycle	86	chr12	122757425	122864999	WES	pancreas
2055	CLN8	ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)	8p23	06383	2079	607837	NP_061764	NM_001034061;NM_018941	ENSP00000328182	candidate	0	0	0	Eukaryotes	0	0	Cell cycle,Cell response to stimuli,Cellular metabolism,Cellular processes,Development,Multicellular activities,Regulation of intracellular processes and metabolism	52	chr8	1719221	1728730	WGS	chronic lymphocytic leukemia
10978	CLP1	CLP1, cleavage and polyadenylation factor I subunit, homolog (S. cerevisiae)	11q12	16382	16999	608757	NP_006822;NP_001136069	NM_006831;NM_001142597	ENSP00000304704	known	1	0	0	Eukaryotes	0	1	DNA/RNA metabolism and transcription,Regulation of transcription	101	chr11	57426949	57428905	CGC	leukemia
63967	CLSPN	claspin	1p34.2	09257	19715	605434	NP_071394;NP_001177410	NM_022111;NM_001190481	-	candidate	0	0	0	Metazoans	26	6	Cellular metabolism,DNA/RNA metabolism and transcription	4	chr1	36202100	36230927	WGS	prostate
64084	CLSTN2	calsyntenin 2	3q23	13077	17448	611323	NP_071414	NM_022131	ENSP00000402460	candidate	0	0	0	Metazoans	0	1	Cell motility and interactions	22	chr3	139654217	140285092	WES	colorectal,head and neck squamous cell carcinoma
1213	CLTC	clathrin, heavy chain (Hc)	17q11-qter	00350	2092	118955	NP_004850	NM_004859	ENSP00000269122	known	1	0	1	Eukaryotes	153	3	Cellular processes	109	chr17	57721637	57771210	CGC	kidney,lymphoma
8218	CLTCL1	clathrin, heavy chain-like 1	22q11.2|22q11.21	03172	2093	601273	NP_009029;NP_001826	NM_007098;NM_001835	ENSP00000439662;ENSP00000445677	known	1	0	1	Eukaryotes	10	0	Cellular processes	32	chr22	19168245	19279164	CGC,WGS	lymphoma,glioblastoma
1240	CMKLR1	chemokine-like receptor 1	12q24.1	03829	2121	602351	NP_001135817;NP_004063;NP_001135815;NP_001135816	NM_001142345;NM_004072;NM_001142343;NM_001142344	ENSP00000311733;ENSP00000401293	candidate	0	0	0	Vertebrates	0	0	Cell motility and interactions,Development,Signal transduction	47	chr12	108685621	108686736	HTMS	breast,lung,ovarian,pancreas,prostate
202333	CMYA5	cardiomyopathy associated 5	5q14.1	16728	14305	612193	NP_705838	NM_153610	ENSP00000394770	candidate	0	0	0	Last Universal Common Ancestor	15	0	-1	-1	chr5	78985731	79095436	WGS	lung
7555	CNBP	CCHC-type zinc finger, nucleic acid binding protein	3q21	00311	13164	116955	NP_001120668;NP_001120665;NP_003409;NP_001120667;NP_001120664;NP_001120666	NM_001127196;NM_001127193;NM_003418;NM_001127195;NM_001127192;NM_001127194	-	known	1	0	0	Eukaryotes	71	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	109	chr3	128889299	128890600	CGC	bone cyst
55748	CNDP2	CNDP dipeptidase 2 (metallopeptidase M20 family)	18q22.3	09893	24437	169800	NP_060705;NP_001161971	NM_018235;NM_001168499	-	candidate	0	0	0	Last Universal Common Ancestor	5	5	Cellular metabolism	105	chr18	72167209	72187300	WGS	melanoma
1258	CNGB1	cyclic nucleotide gated channel beta 1	16q13	07204	2151	600724	NP_001288;NP_001129111	NM_001297;NM_001135639	ENSP00000311670	candidate	0	0	0	Eukaryotes	0	1	Cell response to stimuli,Cellular processes	22	chr16	57918071	58001190	WGS	prostate
26504	CNNM4	cyclin M4	2q11	07420	105	607805	NP_064569	NM_020184	ENSP00000366275	candidate	0	0	0	Last Universal Common Ancestor	0	1	Cellular processes	21	chr2	97426737	97475251	WES	breast
23019	CNOT1	CCR4-NOT transcription complex, subunit 1	16q21	11999	7877	604917	NP_057368;NP_996882	NM_016284;NM_206999	ENSP00000455635;ENSP00000320949;ENSP00000413113	candidate	0	0	0	Eukaryotes	28	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	109	chr16	58554865	58633241	WGS	prostate
4849	CNOT3	CCR4-NOT transcription complex, subunit 3	19q13.4	05368	7879	604910	NP_055331	NM_014516	ENSP00000221232	candidate	0	0	0	Eukaryotes	17	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	68	chr19	54646854	54659142	WES,WGS	chronic lymphocytic leukemia
25927	CNRIP1	cannabinoid receptor interacting protein 1	2p14	12813	24546	-	NP_056278;NP_001104571	NM_015463;NM_001111101	ENSP00000263655	candidate	0	0	0	Metazoans	2	0	-1	-1	chr2	68520997	68546532	WGS	liver
1272	CNTN1	contactin 1	12q11-q12	07189	2171	600016	NP_001834;NP_001242992;NP_778203;NP_001242993	NM_001843;NM_001256063;NM_175038;NM_001256064	ENSP00000448004;ENSP00000448653;ENSP00000447006	candidate	0	0	0	Eukaryotes	2	0	Signal transduction	62	chr12	41302235	41463834	WES	gastric
6900	CNTN2	contactin 2 (axonal)	1q32.1	01826	2172	190197	NP_005067	NM_005076	ENSP00000330633	candidate	0	0	0	Eukaryotes	37	0	Cell cycle,Cell motility and interactions,Development	21	chr1	205022314	205042890	WES	acute myeloid leukemia
5067	CNTN3	contactin 3 (plasmacytoma associated)	3p12.3	-	2173	601325	NP_065923	NM_020872	ENSP00000263665	candidate	0	0	0	Metazoans	1	0	-1	-1	chr3	74313555	74570263	WES	breast
152330	CNTN4	contactin 4	3p26.3	16239	2174	607280	NP_783200;NP_001193884;NP_783302;NP_001193885	NM_175612;NM_175607;NM_001206955;NM_175613;NM_001206956	ENSP00000380602;ENSP00000396010	candidate	0	0	0	Metazoans	2	0	Cell cycle,Cell motility and interactions,Development,Multicellular activities,Regulation of intracellular processes and metabolism	-1	chr3	2613188	3097901	WES	colorectal
53942	CNTN5	contactin 5	11q21-q22.2	06241	2175	607219	NP_780775;NP_055176;NP_001230200;NP_001230199	NM_175566;NM_014361;NM_001243271;NM_001243270	ENSP00000433575;ENSP00000435637	candidate	0	0	0	Eukaryotes	70	0	-1	9	chr11	99426946	100226948	WES,WGS	pancreas,melanoma
27255	CNTN6	contactin 6	3p26-p25	06242	2176	607220	NP_055276	NM_014461	ENSP00000442791	candidate	0	0	0	Eukaryotes	14	0	Development,Signal transduction	15	chr3	1189693	1445099	WES	breast
8506	CNTNAP1	contactin associated protein 1	17q21	03825	8011	602346	NP_003623	NM_003632	ENSP00000264638	candidate	0	0	0	Eukaryotes	16	1	Cell motility and interactions,Regulation of intracellular processes and metabolism,Signal transduction	80	chr17	40834848	40850925	WES	pancreas
26047	CNTNAP2	contactin associated protein-like 2	7q35	05197	13830	604569	NP_054860	NM_014141	ENSP00000354778	candidate	0	0	0	Eukaryotes	4	2	Multicellular activities,Signal transduction	52	chr7	146471359	148112705	WES	head and neck squamous cell carcinoma,lung,pancreas
11064	CNTRL	centriolin	9q33.2	05691	1858	605496	NP_008949	NM_007018	ENSP00000238341	known	1	0	0	Opisthokonts	7	2	-1	35	chr9	123850605	123937502	CGC	myeloma,non-hodgkin lymphoma
1301	COL11A1	collagen, type XI, alpha 1	1p21	00375	2186	120280	NP_542197;NP_542196;NP_001845;NP_001177638	NM_080630;NM_080629;NM_001854;NM_001190709	ENSP00000302551;ENSP00000359114;ENSP00000351163	candidate	0	0	0	Last Universal Common Ancestor	3	1	Cell motility and interactions,Cell response to stimuli,Cellular processes,Development	31	chr1	103343578	103573734	WES	breast,lung
1302	COL11A2	collagen, type XI, alpha 2	6p21.3	09049	2187	120290	NP_542410;NP_542411;NP_001157243;NP_542412	NM_080679;NM_080680;NM_001163771;NM_080681	ENSP00000378620;ENSP00000355123;ENSP00000339915;ENSP00000363840	candidate	0	0	0	Last Universal Common Ancestor	9	0	Cell motility and interactions,Cell response to stimuli,Cellular processes,Development	88	chr6	33131458	33160017	WGS	prostate
1308	COL17A1	collagen, type XVII, alpha 1	10q24.3	00223	2194	113811	NP_000485	NM_000494;NM_130778	ENSP00000340937	candidate	0	0	0	Eukaryotes	8	3	Cell motility and interactions,Cellular processes,Development	15	chr10	105791996	105840431	WGS	glioblastoma
1310	COL19A1	collagen, type XIX, alpha 1	6q12-q13	00364	2196	120165	NP_001849	NM_001858	-	candidate	0	0	0	Eukaryotes	1	0	Cell motility and interactions,Cellular processes,Development	10	chr6	70589460	70916975	WES	breast
1277	COL1A1	collagen, type I, alpha 1	17q21.33	00362	2197	120150	NP_000079	NM_000088	ENSP00000225964	known	1	0	0	Last Universal Common Ancestor	3	9	Cell response to stimuli,Cellular processes,Development	87	chr17	48262866	48278874	CGC,WGS	bone cyst,sarcoma,breast
1278	COL1A2	collagen, type I, alpha 2	7q22.1	00363	2198	120160	NP_000080	NM_000089	ENSP00000297268	candidate	0	0	0	Last Universal Common Ancestor	22	2	Cell response to stimuli,Cellular processes,Development,Signal transduction	97	chr7	94024344	94059702	WES	head and neck squamous cell carcinoma
169044	COL22A1	collagen, type XXII, alpha 1	8q24.3	09885	22989	610026	NP_690848	NM_152888	ENSP00000303153	candidate	0	0	0	Last Universal Common Ancestor	1	0	-1	-1	chr8	139601499	139895415	WES	head and neck squamous cell carcinoma,lung
84570	COL25A1	collagen, type XXV, alpha 1	4q25	09886	18603	610004	NP_115907;NP_942014;NP_001243003	NR_045756;NM_032518;NM_198721;NM_001256074	ENSP00000382078;ENSP00000382077	candidate	0	0	0	Last Universal Common Ancestor	3	0	Cellular processes	-1	chr4	109740408	110223175	WES	chronic lymphocytic leukemia
1281	COL3A1	collagen, type III, alpha 1	2q31	00365	2201	120180	NP_000081	NM_000090	ENSP00000304408	candidate	0	0	0	Last Universal Common Ancestor	12	4	Cell motility and interactions,Cell response to stimuli,Cellular metabolism,Cellular processes,Development,Immune system response,Multicellular activities,Regulation of transcription,Signal transduction	89	chr2	189839216	189876497	WES	colorectal,glioblastoma
1284	COL4A2	collagen, type IV, alpha 2	13q34	00355	2203	120090	NP_001837	NM_001846	ENSP00000353654	candidate	0	0	0	Last Universal Common Ancestor	32	4	Cell motility and interactions,Cellular processes,Development	95	chr13	110960251	111164535	WES	lung
1289	COL5A1	collagen, type V, alpha 1	9q34.2-q34.3	00368	2209	120215	NP_000084	NM_000093	ENSP00000360882	candidate	0	0	0	Last Universal Common Ancestor	13	1	Cellular processes	65	chr9	137534034	137734146	WES,WGS	pancreas,prostate
1294	COL7A1	collagen, type VII, alpha 1	3p21.1	00358	2214	120120	NP_000085	NM_000094	ENSP00000332371	candidate	0	0	0	Last Universal Common Ancestor	6	0	Cellular processes,Development	55	chr3	48602214	48632592	WES	breast
8533	COPS3	COP9 constitutive photomorphogenic homolog subunit 3 (Arabidopsis)	17p11.2	07262	2239	604665	NP_003644;NP_001186054	NM_003653;NM_001199125	ENSP00000437606;ENSP00000268717	known	0	0	0	Eukaryotes	72	3	Cell response to stimuli,Development,Signal transduction	98	chr17	17150415	17184500	CGC,Amplified	
64708	COPS7B	COP9 constitutive photomorphogenic homolog subunit 7B (Arabidopsis)	2q37.1	09889	16760	-	NP_073567	NM_022730	ENSP00000386880	candidate	0	0	0	Eukaryotes	27	4	-1	30	chr2	232653281	232672352	WGS	liver
1345	COX6C	cytochrome c oxidase subunit VIc	8q22.2	00494	2285	124090	NP_004365	NM_004374	ENSP00000428895	known	1	0	3	Metazoans	7	0	-1	109	chr8	100899736	100904249	CGC	uterus
27151	CPAMD8	C3 and PZP-like, alpha-2-macroglobulin domain containing 8	19p13.11	09892	23228	608841	NP_056507	NM_015692	ENSP00000402505	candidate	0	0	0	Metazoans	7	1	-1	-1	chr19	17003922	17137593	WES	breast,colorectal
1362	CPD	carboxypeptidase D	17q11.2	04375	2301	603102	NP_001295;NP_001186704	NM_001304;NM_001199775	ENSP00000225719	candidate	0	0	0	Last Universal Common Ancestor	1	5	Cellular metabolism	98	chr17	28705999	28791829	WGS	liver
1373	CPS1	carbamoyl-phosphate synthase 1, mitochondrial	2q35	01995	2323	608307	NP_001866;NP_001116106;NP_001116105	NM_001875;NM_001122634;NM_001122633	ENSP00000402608;ENSP00000406136;ENSP00000233072	candidate	0	0	0	Last Universal Common Ancestor	22	0	Cellular metabolism	71	chr2	211421443	211542706	WES	lymphoma
54504	CPVL	carboxypeptidase, vitellogenic-like	7p15.1	07479	14399	609780	NP_112601;NP_061902	NM_031311;NM_019029	ENSP00000379572;ENSP00000265394	candidate	0	0	0	Last Universal Common Ancestor	7	0	Cellular metabolism	50	chr7	29035391	29160677	WGS	prostate
1378	CR1	complement component (3b/4b) receptor 1 (Knops blood group)	1q32	00398	2334	120620	NP_000642;NP_000564	NM_000651;NM_000573	ENSP00000383744	candidate	0	0	1	Last Universal Common Ancestor	1	0	Cell response to stimuli,Cellular metabolism,Immune system response	82	chr1	207669613	207803973	WGS	prostate
1385	CREB1	cAMP responsive element binding protein 1	2q34	00442	2345	123810	NP_604391;NP_004370	NM_134442;NM_004379	-	known	1	0	0	Metazoans	33	5	Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	90	chr2	208420360	208461779	CGC	histiocytoma,sarcoma
90993	CREB3L1	cAMP responsive element binding protein 3-like 1	11p11.2	16751	18856	-	NP_443086	NM_052854	ENSP00000434939	known	1	0	0	Eukaryotes	4	0	Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	59	chr11	46299663	46342080	CGC	sarcoma
64764	CREB3L2	cAMP responsive element binding protein 3-like 2	7q34	16391	23720	608834	NP_001240704;NP_919047	NM_001253775;NM_194071	ENSP00000410314;ENSP00000329140	known	1	0	0	Eukaryotes	12	5	Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	104	chr7	137565225	137686451	CGC	sarcoma
1387	CREBBP	CREB binding protein	16p13.3	02534	2348	600140	NP_004371;NP_001073315	NM_004380;NM_001079846	ENSP00000262367	known	1	1	0	Eukaryotes	364	1	Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	97	chr16	3777722	3929917	CGC,WES	leukemia,lymphoma,non-hodgkin lymphoma,bladder
1390	CREM	cAMP responsive element modulator	10p11.21	00444	2352	123812	NP_898831;NP_877571;NP_898883;NP_874392;NP_877572;NP_898829;NP_001872;NP_874386;NP_874390;NP_874388;NP_874393;NP_853549;NP_874391;NP_878273;NP_874387;NP_877570;NP_877573;NP_874389;NP_878270;NP_898830;NP_874394	NM_183013;NM_182770;NM_183060;NM_182723;NM_182771;NM_183011;NM_001881;NM_182717;NM_182721;NM_182719;NM_182724;NM_181571;NM_182722;NM_182853;NM_182718;NM_182769;NM_182772;NM_182720;NM_182850;NM_183012;NM_182725	ENSP00000363858;ENSP00000265372;ENSP00000349387;ENSP00000354593;ENSP00000333055;ENSP00000409220;ENSP00000363860	candidate	0	0	0	Metazoans	34	0	Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	90	chr10	35426764	35500728	WGS	liver
285464	CRIPAK	cysteine-rich PAK1 inhibitor	4p16.3	08753	26619	610203	NP_787114	NM_175918	ENSP00000323978	candidate	0	0	5	Eukaryotes	4	0	Cell response to stimuli,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction	-1	chr4	1388300	1389637	WGS	lymphoma
64109	CRLF2	cytokine receptor-like factor 2	Xp22.3; Yp11.3	02288	14281	400023	NP_001012288;NP_071431	NM_001012288;NM_022148	ENSP00000370979	known	1	0	1	Vertebrates	3	0	-1	25	chrX	1314893	1331527	CGC	leukemia
9696	CROCC	ciliary rootlet coiled-coil, rootletin	1p36.13	16758	21299	-	NP_055490	NM_014675	ENSP00000364691	candidate	0	0	1	Last Universal Common Ancestor	3	0	Cellular processes,Development	45	chr1	17248514	17298938	WGS	lymphoma
23373	CRTC1	CREB regulated transcription coactivator 1	19p13.11	06339	16062	607536	NP_001091952;NP_056136	NM_001098482;NM_015321;NM_025021	ENSP00000345001	known	1	0	1	Metazoans	3	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	58	chr19	18794513	18888189	CGC	salivary
64784	CRTC3	CREB regulated transcription coactivator 3	15q26.1	13384	26148	608986	NP_073606;NP_001036039	NM_022769;NM_001042574	ENSP00000416573	known	1	0	0	Metazoans	8	6	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	109	chr15	91073304	91185369	CGC	salivary
1417	CRYBB3	crystallin, beta B3	22q11.2-q12.1|22q11.23	00431	2400	123630	NP_004067	NM_004076	ENSP00000215855	candidate	0	0	0	Last Universal Common Ancestor	5	0	Cell response to stimuli	0	chr22	25597364	25603176	WGS	lung
1442	CSH1	chorionic somatomammotropin hormone 1 (placental lactogen)	17q24.2	08350	2440	150200	NP_001308	NM_001317;NM_022641;NM_022640	ENSP00000316416	candidate	0	0	3	Vertebrates	6	0	Signal transduction	9	chr17	61972385	61973599	WES	melanoma
64478	CSMD1	CUB and Sushi multiple domains 1	8p23.2	10523	14026	608397	NP_150094	NM_033225	ENSP00000334828	candidate	0	0	0	Last Universal Common Ancestor	13	0	-1	-1	chr8	2796110	4851938	WGS	breast
114784	CSMD2	CUB and Sushi multiple domains 2	1p34.3	13094	19290	608398	NP_443128	NM_052896	ENSP00000241312	candidate	0	0	0	Last Universal Common Ancestor	6	0	-1	-1	chr1	33985121	34631414	WES	acute myeloid leukemia
114788	CSMD3	CUB and Sushi multiple domains 3	8q23.3	16329	19291	608399	NP_443132;NP_937756;NP_937757	NM_052900;NM_198123;NM_198124	ENSP00000412263;ENSP00000297405;ENSP00000345799	candidate	0	0	0	Last Universal Common Ancestor	1	0	-1	-1	chr8	113237003	114449083	WES	chronic lymphocytic leukemia,colorectal,gastric,head and neck squamous cell carcinoma,kidney,liver
1460	CSNK2B	casein kinase 2, beta polypeptide	6p21-p12|6p21.3	00278	2460	115441	NP_001311	NM_001320	ENSP00000365042	candidate	0	0	0	Eukaryotes	302	0	Signal transduction	36	chr6	31634609	31637700	WES,WGS	medulloblastoma,liver
79848	CSPP1	centrosome and spindle pole associated protein 1	8q13.2	07991	26193	611654	NP_079066	NM_001077204;NM_024790	ENSP00000262210	candidate	0	0	0	Eukaryotes	2	0	-1	35	chr8	67976634	68107825	WES	breast
1488	CTBP2	C-terminal binding protein 2	10q26.13	04016	2495	602619	NP_001077383;NP_073713;NP_001320	NM_001083914;NM_022802;NM_001329	ENSP00000338615	candidate	0	0	0	Last Universal Common Ancestor	87	2	Cell cycle,Other,Regulation of intracellular processes and metabolism	106	chr10	126678090	126716328	WGS	glioblastoma,lymphoma
80169	CTC1	CTS telomere maintenance complex component 1	17p13.1	07980	26169	613129	NP_079375	NM_025099	-	candidate	0	0	0	Metazoans	1	0	-1	24	chr17	8131501	8146466	WGS	lymphoma
10664	CTCF	CCCTC-binding factor (zinc finger protein)	16q21-q22.3	05005	13723	604167	NP_006556;NP_001177951	NM_006565;NM_001191022	ENSP00000384707;ENSP00000264010	candidate	0	0	0	Last Universal Common Ancestor	4	4	Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	100	chr16	67644736	67671772	WES	breast
23399	CTDNEP1	CTD nuclear envelope phosphatase 1	17p13	16845	19085	610684	NP_001137247;NP_056158	NM_001143775;NM_015343	ENSP00000460683;ENSP00000321732	candidate	0	0	2	Eukaryotes	1	3	Cellular processes	104	chr17	7147507	7154615	WES,WGS	medulloblastoma
9811	CTIF	CBP80/20-dependent translation initiation factor	18q21.1	11083	23925	613178	NP_001135869;NP_055587	NM_001142397;NM_014772	ENSP00000256413	candidate	0	0	0	Metazoans	1	0	DNA/RNA metabolism and transcription	52	chr18	46145937	46385927	WES	breast
1496	CTNNA2	catenin (cadherin-associated protein), alpha 2	2p12-p11.1	00228	2510	114025	NP_004380;NP_001158355	NM_004389;NM_001164883	ENSP00000419295	candidate	0	0	2	Eukaryotes	5	0	-1	41	chr2	79878683	80874994	WES	pancreas
29119	CTNNA3	catenin (cadherin-associated protein), alpha 3	10q22.2	09639	2511	607667	NP_001120856;NP_037398	NM_001127384;NM_013266	ENSP00000362849;ENSP00000389714	candidate	0	0	0	Eukaryotes	2	0	-1	17	chr10	67680091	69407271	WGS	glioblastoma
1499	CTNNB1	catenin (cadherin-associated protein), beta 1, 88kDa	3p21	00286	2514	116806	NP_001091679;NP_001091680;NP_001895	NM_001098209;NM_001098210;NM_001904	ENSP00000379488;ENSP00000379486;ENSP00000344456	known	1	0	0	Eukaryotes	369	9	Cell cycle,Cell motility and interactions,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Multicellular activities,Other,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	102	chr3	41266016	41280830	CGC,HTMS,WES,WGS	colorectal,liver,other,ovarian,salivary,breast,lung,pancreas,prostate,sarcoma,colorectal (non-hypermutated),gastric,medulloblastoma
8452	CUL3	cullin 3	2q36.2	09123	2553	603136	NP_003581	NM_003590	ENSP00000343601;ENSP00000264414	candidate	0	0	0	Eukaryotes	1157	2	Cell cycle,Cellular metabolism,Development,Regulation of intracellular processes and metabolism	103	chr2	225338965	225449726	WGS	liver,prostate
9820	CUL7	cullin 7	6p21.1	09901	21024	609577	NP_001161842;NP_055595	NM_001168370;NM_014780	ENSP00000438788;ENSP00000265348	candidate	0	0	0	Eukaryotes	24	1	Cellular metabolism,Development	82	chr6	43005429	43021596	WES	kidney
1523	CUX1	cut-like homeobox 1	7q22.1	00295	2557	116896	NP_001904;NP_001189475;NP_853530;NP_001189474;NP_852477;NP_001189473;NP_001189472	NM_001913;NM_001202546;NM_181552;NM_001202545;NM_181500;NM_001202544;NM_001202543	ENSP00000353401;ENSP00000449371;ENSP00000409745;ENSP00000377410;ENSP00000292538;ENSP00000414091;ENSP00000292535	candidate	0	0	0	Opisthokonts	30	1	Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription	96	chr7	101459311	101892319	WES	colorectal
10663	CXCR6	chemokine (C-X-C motif) receptor 6	3p21	05520	16647	605163	NP_006555	NM_006564	ENSP00000304414	candidate	0	0	0	Vertebrates	0	1	Other,Signal transduction	38	chr3	45987974	45988999	WGS	chronic lymphocytic leukemia
57007	CXCR7	chemokine (C-X-C motif) receptor 7	2q37.3	09882	23692	610376	NP_064707	NM_020311;NM_001047841	ENSP00000272928	known	1	0	0	Vertebrates	3	2	Signal transduction	67	chr2	237489109	237490194	CGC	lipoma
51167	CYB5R4	cytochrome b5 reductase 4	6pter-q22.33	12218	20147	608343	NP_057314	NM_016230	ENSP00000358695	candidate	0	0	0	Last Universal Common Ancestor	0	3	Cell response to stimuli,Cellular metabolism	73	chr6	84569502	84669594	WES	breast
23191	CYFIP1	cytoplasmic FMR1 interacting protein 1	15q11	05890	13759	606322	NP_055423;NP_001028200	NM_014608;NM_001033028	ENSP00000454199	candidate	0	0	1	Eukaryotes	17	1	Cell cycle,Development,Regulation of intracellular processes and metabolism	104	chr15	22925783	23003037	WES,WGS	pancreas,liver
114757	CYGB	cytoglobin	17q25	06479	16505	608759	NP_599030	NM_134268	ENSP00000293230	candidate	0	0	0	Eukaryotes	2	1	Cellular processes	-1	chr17	74527060	74533624	WGS	lymphoma
1540	CYLD	cylindromatosis (turban tumor syndrome)	16q12.1	05427	2584	605018	NP_001035877;NP_056062;NP_001035814	NM_001042412;NM_015247;NM_001042355	ENSP00000445447;ENSP00000392025	known	0	1	0	Metazoans	49	4	Cell cycle,Cellular metabolism,Regulation of intracellular processes and metabolism,Regulation of transcription	99	chr16	50783610	50830416	CGC	cylindroma
1543	CYP1A1	cytochrome P450, family 1, subfamily A, polypeptide 1	15q24.1	00148	2595	108330	NP_000490	NM_000499	ENSP00000378488	candidate	0	0	1	Last Universal Common Ancestor	1	1	Cellular metabolism	34	chr15	75012833	75015438	WES	breast
1546	CYP2A	cytochrome P450, family 2, subfamily A	19q13.2	-	2607	-	-	-	-	candidate	0	0	-1	Last Universal Common Ancestor	0	0	-1	-1	-	0	0	WGS	lung
1549	CYP2A7	cytochrome P450, family 2, subfamily A, polypeptide 7	19q13.2	07453	2611	608054	NP_000755;NP_085079	NM_000764;NM_030589	ENSP00000301146;ENSP00000291764	candidate	0	0	3	Last Universal Common Ancestor	0	0	-1	67	chr19	41381601	41388115	WES,WGS	chronic lymphocytic leukemia
1562	CYP2C18	cytochrome P450, family 2, subfamily C, polypeptide 18	10q24	03085	2620	601131	NP_000763;NP_001122397	NM_000772;NM_001128925	ENSP00000285979;ENSP00000341293	candidate	0	0	3	Last Universal Common Ancestor	6	0	-1	43	chr10	96443577	96495198	WGS	lung
1559	CYP2C9	cytochrome P450, family 2, subfamily C, polypeptide 9	10q24	03084	2623	601130	NP_000762	NM_000771	ENSP00000260682	candidate	0	0	3	Last Universal Common Ancestor	11	0	-1	95	chr10	96698440	96748782	WES	melanoma
284541	CYP4A22	cytochrome P450, family 4, subfamily A, polypeptide 22	1p33	16776	20575	-	NP_001010969	NM_001010969	-	candidate	0	0	1	Last Universal Common Ancestor	0	1	-1	17	chr1	47603158	47614466	WGS	chronic lymphocytic leukemia
126410	CYP4F22	cytochrome P450, family 4, subfamily F, polypeptide 22	19p13.12	08256	26820	611495	NP_775754	NM_173483	ENSP00000269703	candidate	0	0	0	Last Universal Common Ancestor	0	1	-1	-1	chr19	15636148	15662279	WES	lymphoma
260293	CYP4X1	cytochrome P450, family 4, subfamily X, polypeptide 1	1p33	13110	20244	-	NP_828847	NM_178033	ENSP00000360968	candidate	0	0	0	Last Universal Common Ancestor	1	0	-1	-1	chr1	47489490	47515843	WES	endometrium
117154	DACH2	dachshund homolog 2 (Drosophila)	Xq21.3	06481	16814	300608	NP_001132986;NP_444511;NP_001132987	NM_001139514;NM_053281;NM_001139515	ENSP00000362223;ENSP00000420896;ENSP00000362217	candidate	0	0	0	Metazoans	2	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	-1	chrX	85403625	86087155	WES	pancreas
221955	DAGLB	diacylglycerol lipase, beta	7p22.1	17324	28923	614016	NP_631918;NP_001136408	NM_139179;NM_001142936	ENSP00000391171;ENSP00000297056	candidate	0	0	0	Eukaryotes	3	1	Cellular metabolism	-1	chr7	6449471	6487473	WGS	lymphoma
1616	DAXX	death-domain associated protein	6p21.3	04424	2681	603186	NP_001135442;NP_001135441;NP_001241646;NP_001341	NM_001141970;NM_001141969;NM_001254717;NR_024517;NM_001350	ENSP00000363668;ENSP00000396876;ENSP00000266000	known	0	1	0	Metazoans	103	1	Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	64	chr6	33286523	33290691	CGC,WES	glioblastoma,pancreas
1627	DBN1	drebrin 1	5q35.3	00545	2695	126660	NP_543157;NP_004386	NM_080881;NM_004395	ENSP00000308532;ENSP00000292385	candidate	0	0	0	Eukaryotes	68	3	Cell cycle,Cellular processes,Development,Multicellular activities	67	chr5	176884437	176899211	WES	breast
51163	DBR1	debranching enzyme homolog 1 (S. cerevisiae)	3q22.3	07384	15594	607024	NP_057300	NM_016216	ENSP00000260803	candidate	0	0	0	Last Universal Common Ancestor	2	0	DNA/RNA metabolism and transcription,Regulation of transcription	27	chr3	137880734	137893637	WES	gastric
138009	DCAF4L2	DDB1 and CUL4 associated factor 4-like 2	8q21.3	08187	26657	-	NP_689631	NM_152418	ENSP00000316496	candidate	0	0	1	Eukaryotes	0	1	-1	-1	chr8	88885015	88886199	WES	breast
8642	DCHS1	dachsous 1 (Drosophila)	11p15.4	04341	13681	603057	NP_003728	NM_003737;NM_024542	ENSP00000299441	candidate	0	0	0	Last Universal Common Ancestor	1	0	Cell motility and interactions	57	chr11	6643013	6662844	WES	lymphoma
51164	DCTN4	dynactin 4 (p62)	5q31-q32	13126	15518	-	NP_001129116;NP_001129115;NP_057305	NM_001135644;NM_001135643;NM_016221	ENSP00000411251;ENSP00000416968	candidate	0	0	0	Eukaryotes	8	2	-1	70	chr5	150090714	150138555	WGS	prostate
54165	DCUN1D1	DCN1, defective in cullin neddylation 1, domain containing 1 (S. cerevisiae)	3q26.3	12067	18184	605905	NP_065691	NM_020640	-	known	0	0	2	Eukaryotes	219	2	-1	90	chr3	182662885	182683541	CGC,Amplified	
1643	DDB2	damage-specific DNA binding protein 2, 48kDa	11p12-p11	02886	2718	600811	NP_000098	NM_000107	ENSP00000256996	known	0	1	0	Last Universal Common Ancestor	44	2	Cell response to stimuli,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription	59	chr11	47236688	47260397	CGC	
1649	DDIT3	DNA-damage-inducible transcript 3	12q13.1-q13.2	00529	2726	126337	NP_001181982;NP_001181983;NP_001181986;NP_004074;NP_001181984;NP_001181985	NM_001195053;NM_001195054;NM_001195057;NM_004083;NM_001195055;NM_001195056	ENSP00000448665;ENSP00000447803;ENSP00000447188;ENSP00000340671	known	1	0	0	Vertebrates	42	2	Cell cycle,Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	68	chr12	57910595	57911258	CGC	sarcoma
1662	DDX10	DEAD (Asp-Glu-Ala-Asp) box polypeptide 10	11q22-q23	03138	2735	601235	NP_004389	NM_004398	ENSP00000314348	known	1	0	1	Last Universal Common Ancestor	5	5	-1	104	chr11	108535881	108811147	CGC	leukemia
1663	DDX11	DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11	12p11	03095	2736	601150	NP_004390;NP_085911;NP_689651	NM_030655;NM_004399;NM_030653;NM_152438	ENSP00000440402;ENSP00000228264;ENSP00000309965;ENSP00000384703	candidate	0	0	2	Last Universal Common Ancestor	10	0	Cell cycle,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism	82	chr12	31231328	31256964	WGS	breast
55794	DDX28	DEAD (Asp-Glu-Ala-Asp) box polypeptide 28	16q22.1	06357	17330	607618	NP_060850	NM_018380	ENSP00000332340	candidate	0	0	0	Last Universal Common Ancestor	23	1	-1	42	chr16	68055486	68057105	WGS	lymphoma
1654	DDX3X	DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, X-linked	Xp11.3-p11.23	02154	2745	300160	NP_001347;NP_001180345;NP_001180346	NM_001356;NM_024005;NM_001193416;NM_001193417	ENSP00000382840	candidate	0	0	3	Last Universal Common Ancestor	127	12	-1	108	chrX	41193506	41206969	WES,WGS	chronic lymphocytic leukemia,head and neck squamous cell carcinoma,lymphoma,medulloblastoma
1655	DDX5	DEAD (Asp-Glu-Ala-Asp) box polypeptide 5	17q21	01615	2746	180630	NP_004387	NM_004396	-	known	1	0	0	Last Universal Common Ancestor	162	6	Cell cycle,DNA/RNA metabolism and transcription,Regulation of transcription	109	chr17	62496044	62502237	CGC	prostate
1656	DDX6	DEAD (Asp-Glu-Ala-Asp) box polypeptide 6	11q23.3	02638	2747	600326	NP_004388	NM_004397	-	known	1	0	2	Last Universal Common Ancestor	18	10	-1	33	chr11	118625424	118656960	CGC	non-hodgkin lymphoma
7913	DEK	DEK oncogene	6p22.3	00503	2768	125264	NP_001128181;NP_003463	NM_001134709;NM_003472	ENSP00000380414	known	1	0	0	Eukaryotes	42	4	Cellular metabolism,DNA/RNA metabolism and transcription,Other,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	95	chr6	18226405	18264218	CGC	leukemia
10260	DENND4A	DENN/MADD domain containing 4A	15q22.31	02662	24321	600382	NP_005839;NP_001138295	NM_005848;NM_001144823	ENSP00000391167;ENSP00000396830	candidate	0	0	0	Eukaryotes	6	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	13	chr15	65954192	66048788	WGS	chronic lymphocytic leukemia
23258	DENND5A	DENN/MADD domain containing 5A	11p15.4	11475	19344	-	NP_001230183;NP_056028	NM_001243254;NM_015213	ENSP00000435866;ENSP00000328524	candidate	0	0	0	Eukaryotes	2	0	-1	103	chr11	9161221	9286616	WGS	liver
1716	DGUOK	deoxyguanosine kinase	2p13	03273	2858	601465	NP_550438;NP_550440	NM_001929;NM_080916;NM_080918;NM_080917;NM_080915	ENSP00000264093;ENSP00000306964	candidate	0	0	0	Last Universal Common Ancestor	4	0	Cellular metabolism,DNA/RNA metabolism and transcription	109	chr2	74154038	74185375	WGS	prostate
79947	DHDDS	dehydrodolichyl diphosphate synthase	1p36.11	12183	20603	608172	NP_001230493;NP_079163;NP_995583;NP_001230494	NM_001243564;NM_024887;NM_205861;NM_001243565	ENSP00000353104	candidate	0	0	0	Last Universal Common Ancestor	4	0	-1	76	chr1	26759437	26795619	WGS	breast
1729	DIAPH1	diaphanous homolog 1 (Drosophila)	5q31	03670	2876	602121	NP_005210;NP_001073280	NM_005219;NM_001079812	ENSP00000373709;ENSP00000381565	candidate	0	0	0	Eukaryotes	30	1	Cell response to stimuli,Cellular processes	100	chr5	140896421	140998481	WES	lymphoma
23405	DICER1	dicer 1, ribonuclease type III	14q32.13	05875	17098	606241	NP_001182502;NP_085124;NP_803187	NM_001195573;NM_030621;NM_177438	ENSP00000435681;ENSP00000376783;ENSP00000343745	known	0	1	0	Last Universal Common Ancestor	14	19	Cell cycle,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription	101	chr14	95556838	95599795	CGC,WGS	sarcoma,sex cord-stromal tumour,testis,prostate
11083	DIDO1	death inducer-obliterator 1	20q13.33	12752	2680	604140	NP_542986;NP_071388;NP_149072;NP_542987;NP_001180299;NP_001180298	NM_080796;NM_022105;NM_033081;NM_080797;NM_001193370;NM_001193369	ENSP00000378752;ENSP00000378749;ENSP00000359397;ENSP00000266070;ENSP00000346692;ENSP00000378744	candidate	0	0	0	Eukaryotes	34	1	Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription	93	chr20	61510588	61542964	WGS	lymphoma
22982	DIP2C	DIP2 disco-interacting protein 2 homolog C (Drosophila)	10p15.3	17200	29150	611380	NP_055789	NM_014974	ENSP00000280886	candidate	0	0	0	Last Universal Common Ancestor	2	2	-1	93	chr10	323268	735518	WES	breast,lung
22894	DIS3	DIS3 mitotic control homolog (S. cerevisiae)	13q22.1	06338	20604	607533	NP_055768;NP_001121698	NM_014953;NM_001128226	ENSP00000366997	candidate	0	0	0	Last Universal Common Ancestor	31	1	DNA/RNA metabolism and transcription,Regulation of transcription	80	chr13	73333936	73355970	WES,WGS	myeloma
27123	DKK2	dickkopf 2 homolog (Xenopus laevis)	4q25	05658	2892	605415	NP_055236	NM_014421	ENSP00000285311	candidate	0	0	0	Eukaryotes	10	4	Regulation of intracellular processes and metabolism,Signal transduction	17	chr4	107845114	107956748	WGS	chronic lymphocytic leukemia
10395	DLC1	deleted in liver cancer 1	8p22	05035	2897	604258	NP_079043;NP_006085;NP_001157743;NP_872584	NM_024767;NM_006094;NM_001164271;NM_182643	ENSP00000425878;ENSP00000276297	candidate	0	0	0	Last Universal Common Ancestor	10	5	Cell cycle,Cell motility and interactions,Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction	83	chr8	12943323	13357580	WES	pancreas
9940	DLEC1	deleted in lung and esophageal cancer 1	3p21.3	07234	2899	604050	NP_031361;NP_031363	NM_007338;NM_007335;NM_007336;NM_007337	ENSP00000308597;ENSP00000315914	candidate	0	0	0	Eukaryotes	5	0	Cell cycle,Regulation of intracellular processes and metabolism	47	chr3	38080717	38164093	WES,WGS	pancreas,melanoma
1741	DLG3	discs, large homolog 3 (Drosophila)	Xq13.1	02177	2902	300189	NP_066943;NP_065781;NP_001159750	NM_021120;NM_020730;NM_001166278	ENSP00000441393;ENSP00000363475;ENSP00000363480	candidate	0	0	0	Last Universal Common Ancestor	79	1	Cell cycle,Regulation of intracellular processes and metabolism	91	chrX	69665052	69722116	WES	pancreas
1742	DLG4	discs, large homolog 4 (Drosophila)	17p13.1	04199	2903	602887	NP_001122299;NP_001356	NM_001128827;NM_001365	ENSP00000307471;ENSP00000293813	candidate	0	0	0	Last Universal Common Ancestor	124	1	Development,Multicellular activities,Signal transduction	37	chr17	7094030	7121959	WGS	breast
9231	DLG5	discs, large homolog 5 (Drosophila)	10q23	04972	2904	604090	NP_004738	NM_004747	ENSP00000361467	candidate	0	0	0	Eukaryotes	60	2	Cell cycle,Regulation of intracellular processes and metabolism,Signal transduction	80	chr10	79552201	79686278	WGS	breast
1756	DMD	dystrophin	Xp21.2	02303	2928	300377	NP_004000;NP_004010;NP_004014;NP_004004;NP_004012;NP_004009;NP_004011;NP_004003;NP_004005;NP_004008;NP_004001;NP_003997;NP_003998;NP_004002;NP_000100;NP_004006;NP_004013;NP_004007	NM_004009;NM_004019;NM_004023;NM_004013;NM_004021;NM_004018;NM_004020;NM_004012;NM_004014;NM_004017;NM_004010;NM_004006;NM_004007;NM_004011;NM_000109;NM_004015;NM_004022;NM_004016	ENSP00000354923;ENSP00000367948;ENSP00000367979;ENSP00000367997;ENSP00000444119;ENSP00000352894;ENSP00000340057	candidate	0	0	0	Eukaryotes	44	6	Cellular metabolism,Cellular processes,Development	78	chrX	31152217	33038315	WES,WGS	gastric,chronic lymphocytic leukemia
29958	DMGDH	dimethylglycine dehydrogenase	5q14.1	05789	24475	605849	NP_037523	NM_013391	ENSP00000255189	candidate	0	0	0	Last Universal Common Ancestor	0	2	Cellular metabolism	-1	chr5	78293908	78365443	WGS	liver
10655	DMRT2	doublesex and mab-3 related transcription factor 2	9p24.3	16079	2935	604935	NP_006548;NP_870987;NP_001124337	NM_006557;NM_181872;NM_001130865	ENSP00000371690;ENSP00000259622;ENSP00000305785	candidate	0	0	0	Metazoans	18	1	Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription	-1	chr9	1051614	1057270	WGS	melanoma
63951	DMRTA1	DMRT-like family A1	9p21.3	10913	13826	-	NP_071443	NM_022160	ENSP00000319651	candidate	0	0	0	Metazoans	12	0	Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription	-1	chr9	22447065	22451907	WGS	prostate
1657	DMXL1	Dmx-like 1	5q22	09294	2937	605671	NP_005500	NM_005509	ENSP00000309690	candidate	0	0	0	Last Universal Common Ancestor	2	5	-1	47	chr5	118407265	118582911	WES	liver
56171	DNAH7	dynein, axonemal, heavy chain 7	2q32.3	10914	18661	610061	NP_061720	NM_018897	ENSP00000311273	candidate	0	0	0	Eukaryotes	20	0	Cell motility and interactions,Cellular processes	58	chr2	196602648	196922843	WES	gastric
1769	DNAH8	dynein, axonemal, heavy chain 8	6p21.2	04515	2952	603337	NP_001193856	NM_001206927;NM_001371	ENSP00000333363	candidate	0	0	0	Eukaryotes	1	0	Cell motility and interactions,Cellular processes	-1	chr6	38690586	38998165	WGS	melanoma
1770	DNAH9	dynein, axonemal, heavy chain 9	17p12	04511	2953	603330	NP_001363;NP_004653	NM_001372;NM_004662	ENSP00000262442;ENSP00000379323	candidate	0	0	0	Eukaryotes	1	0	Cellular processes,Development,Multicellular activities	56	chr17	11501816	11872841	WES	pancreas
92737	DNER	delta/notch-like EGF repeat containing	2q36.3	09531	24456	607299	NP_620711	NM_139072	ENSP00000345229	candidate	0	0	0	Eukaryotes	4	0	Cell cycle,Cell motility and interactions,Cellular metabolism,Cellular processes,Development,Multicellular activities,Signal transduction	-1	chr2	230223259	230579139	HTMS,WGS	breast,lung,ovarian,pancreas,prostate
1785	DNM2	dynamin 2	19p13.2	03852	2974	602378	NP_001177645;NP_001005361;NP_001005360;NP_004936;NP_001005362	NM_001190716;NM_001005361;NM_001005360;NM_004945;NM_001005362	ENSP00000347890;ENSP00000373905;ENSP00000386192;ENSP00000352721	known	0	1	2	Last Universal Common Ancestor	108	4	Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	61	chr19	10828919	10941720	CGC	leukemia
1788	DNMT3A	DNA (cytosine-5-)-methyltransferase 3 alpha	2p23	04141	2978	602769	NP_783329;NP_783328;NP_072046;NP_715640	NM_175630;NM_175629;NM_022552;NM_153759	ENSP00000324375;ENSP00000370122;ENSP00000264709;ENSP00000384852	known	0	1	0	Eukaryotes	47	11	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of transcription	20	chr2	25457151	25536853	CGC,WES	leukemia,myelodysplasia
1794	DOCK2	dedicator of cytokinesis 2	5q35.1	09121	2988	603122	NP_004937	NM_004946	ENSP00000256935	candidate	0	0	0	Eukaryotes	16	0	Cell motility and interactions,Cellular processes,Immune system response	21	chr5	169064331	169509859	WES	pancreas
9732	DOCK4	dedicator of cytokinesis 4	7q31.1	07407	19192	607679	NP_055520	NM_014705	ENSP00000410746	candidate	0	0	0	Eukaryotes	8	2	-1	70	chr7	111368333	111846193	WES,WGS	chronic lymphocytic leukemia
57572	DOCK6	dedicator of cytokinesis 6	19p13.2	13243	19189	614194	NP_065863	NM_020812	ENSP00000294618	candidate	0	0	0	Eukaryotes	2	1	-1	62	chr19	11310176	11373116	WGS	prostate
1798	DPAGT1	dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)	11q23.3	01879	2995	191350	NP_001373	NM_203316;NM_001382	ENSP00000346142	candidate	0	0	0	Last Universal Common Ancestor	3	1	Cellular metabolism	95	chr11	118967711	118972365	WES	breast
64180	DPEP3	dipeptidase 3	16q22.1	07012	23029	609926	NP_001123230;NP_071752	NM_001129758;NM_022357	ENSP00000268793	candidate	0	0	0	Last Universal Common Ancestor	1	0	Cellular metabolism	9	chr16	68009671	68014358	WGS	breast
57628	DPP10	dipeptidyl-peptidase 10 (non-functional)	2q14.1	07083	20823	608209	NP_001171507;NP_001171508;NP_001171505;NP_001004360;NP_065919	NM_001178036;NM_001178037;NM_001178034;NM_001004360;NM_020868	ENSP00000386565	candidate	0	0	0	Last Universal Common Ancestor	3	0	Cellular metabolism	-1	chr2	115919534	116599918	WES	colorectal
1804	DPP6	dipeptidyl-peptidase 6	7q36.2	00525	3010	126141	NP_001927;NP_001034439;NP_570629	NM_001936;NM_001039350;NM_130797	ENSP00000385578;ENSP00000367001	candidate	0	0	0	Last Universal Common Ancestor	3	0	Cellular metabolism	73	chr7	153749906	154684187	WES	chronic lymphocytic leukemia,pancreas
1806	DPYD	dihydropyrimidine dehydrogenase	1p22	02036	3012	612779	NP_000101;NP_001153773	NM_000110;NM_001160301	ENSP00000359211;ENSP00000307107	candidate	0	0	0	Last Universal Common Ancestor	2	3	Cellular metabolism,DNA/RNA metabolism and transcription	50	chr1	97544535	98386478	WES	breast,lymphoma
29102	DROSHA	drosha, ribonuclease type III	5p13.3	10196	17904	608828	NP_001093882;NP_037367	NM_001100412;NM_013235	ENSP00000424161;ENSP00000425979	candidate	0	0	0	Last Universal Common Ancestor	21	2	DNA/RNA metabolism and transcription,Regulation of transcription	93	chr5	31401542	31527018	WGS	melanoma
1825	DSC3	desmocollin 3	18q12.1	02604	3037	600271	NP_001932;NP_077741	NM_001941;NM_024423	ENSP00000353608;ENSP00000392068	candidate	0	0	0	Eukaryotes	8	2	Cell motility and interactions	57	chr18	28574144	28622626	WES	lymphoma
57453	DSCAML1	Down syndrome cell adhesion molecule like 1	11q23	10921	14656	611782	NP_065744	NM_020693	ENSP00000315465	candidate	0	0	0	Last Universal Common Ancestor	110	3	Cell cycle,Development	-1	chr11	117299047	117667974	WES	colorectal
29940	DSE	dermatan sulfate epimerase	6q22	05807	21144	605942	NP_037484;NP_001074445	NM_013352;NM_001080976	ENSP00000404049;ENSP00000352567	candidate	0	0	1	Last Universal Common Ancestor	2	1	Cellular metabolism	63	chr6	116720414	116758505	WES	liver
1830	DSG3	desmoglein 3	18q12.1	01355	3050	169615	NP_001935	NM_001944	ENSP00000257189	candidate	0	0	0	Eukaryotes	4	0	Cell motility and interactions	57	chr18	29027841	29056220	WGS	lung
147409	DSG4	desmoglein 4	18q12.1	06387	21307	607892	NP_001127925;NP_817123	NM_001134453;NM_177986	ENSP00000311859	candidate	0	0	0	Eukaryotes	1	0	Cell motility and interactions,Development,Multicellular activities	-1	chr18	28956875	28993555	WES	glioblastoma
1834	DSPP	dentin sialophosphoprotein	4q21.3	00508	3054	125485	NP_055023	NM_014208	ENSP00000382213	candidate	0	0	0	Last Universal Common Ancestor	0	0	Cell response to stimuli,Development	31	chr4	88532061	88537717	WGS	lymphoma
667	DST	dystonin	6p12.1	00222	1090	113810	NP_056363;NP_001714	NM_015548;NM_183380;NM_001144771;NM_001144769;NM_001144770;NM_001723;NM_020388	ENSP00000359801;ENSP00000244364	candidate	0	0	0	Eukaryotes	60	4	Cell cycle,Cellular processes,Signal transduction	96	chr6	56323806	56507586	WGS	lung
1837	DTNA	dystrobrevin, alpha	18q12	03141	3057	601239	NP_116763;NP_116760;NP_001185874;NP_001185870;NP_116757;NP_001185872;NP_001383;NP_001121647;NP_001185867;NP_001185873;NP_116761;NP_001185868;NP_001185871;NP_001185869;NP_001382;NP_001381;NP_116762	NM_032981;NM_032978;NM_001198945;NM_001198941;NM_032975;NM_001198943;NM_001392;NM_001128175;NM_001198938;NM_001198944;NM_032979;NM_001198939;NM_001198942;NM_001198940;NM_001391;NM_001390;NM_032980	ENSP00000451516;ENSP00000470152;ENSP00000382072;ENSP00000473078;ENSP00000405819;ENSP00000269191;ENSP00000322519;ENSP00000283365;ENSP00000336682	candidate	0	0	0	Metazoans	28	0	Multicellular activities,Signal transduction	89	chr18	32335941	32462168	WES	chronic lymphocytic leukemia
1838	DTNB	dystrobrevin, beta	2p24	09091	3058	602415	NP_899204;NP_001243237;NP_001243232;NP_149160;NP_899205;NP_068707;NP_149159;NP_001243233	NM_183360;NM_001256308;NM_001256303;NM_033148;NM_183361;NM_021907;NM_033147;NM_001256304	ENSP00000385784;ENSP00000444463;ENSP00000384084;ENSP00000385482;ENSP00000384767;ENSP00000385193;ENSP00000384787	candidate	0	0	0	Metazoans	27	1	-1	41	chr2	25606703	25875529	WES	colorectal
1844	DUSP2	dual specificity phosphatase 2	2q11	04348	3068	603068	NP_004409	NM_004418	ENSP00000288943	candidate	0	0	0	Last Universal Common Ancestor	2	6	Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction	20	chr2	96809565	96811093	WES	lymphoma
56940	DUSP22	dual specificity phosphatase 22	6p25.3	13255	16077	-	NP_064570	NM_020185	-	candidate	0	0	0	Last Universal Common Ancestor	7	2	Cell cycle,Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction	99	chr6	311879	350865	WGS	lung
1849	DUSP7	dual specificity phosphatase 7	3p21	04125	3073	602749	NP_001938	NM_001947	ENSP00000417183	candidate	0	0	0	Last Universal Common Ancestor	10	1	Cellular metabolism,Cellular processes	8	chr3	52084834	52090382	WES	lymphoma
1850	DUSP8	dual specificity phosphatase 8	11p15.5	03617	3074	602038	NP_004411	NM_004420	ENSP00000380530	candidate	0	0	5	Last Universal Common Ancestor	2	4	Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction	49	chr11	1577751	1587056	WGS	lymphoma
1852	DUSP9	dual specificity phosphatase 9	Xq28	02136	3076	300134	NP_001386	NM_001395	ENSP00000359186	candidate	0	0	0	Last Universal Common Ancestor	7	1	Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction	53	chrX	152913408	152915757	WES	lymphoma
22947	DUX4	double homeobox 4	4q35	16189	3082	606009	NP_149418	NM_033178	ENSP00000451304	known	1	0	20	-	15	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	0	chr4	190992204	190993658	CGC	sarcoma
79659	DYNC2H1	dynein, cytoplasmic 2, heavy chain 1	11q21-q22.1	-	2962	603297	NP_001073932;NP_001368	NM_024606;NM_001080463;NM_001377	ENSP00000381167;ENSP00000364887	candidate	0	0	0	Eukaryotes	63	4	Cellular processes,Development	55	chr11	102980304	103349978	WGS	breast
8445	DYRK2	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2	12q15	04606	3093	603496	NP_006473;NP_003574	NM_006482;NM_003583	-	known	0	0	0	Last Universal Common Ancestor	115	4	Cell cycle,Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction	54	chr12	68042914	68052490	CGC,Amplified	
1871	E2F3	E2F transcription factor 3	6p22	02693	3115	600427	NP_001940;NP_001230005	NM_001949;NM_001243076	ENSP00000443418;ENSP00000262904	known	0	0	1	Eukaryotes	36	15	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	75	chr6	20402464	20490658	CGC,Amplified	
1879	EBF1	early B-cell factor 1	5q34	01256	3126	164343	NP_076870	NM_024007	ENSP00000322898	known	1	0	1	Metazoans	6	1	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	-1	chr5	158134988	158526486	CGC	lipoma
345930	ECT2L	epithelial cell transforming sequence 2 oncogene-like	6q24.1	-	21118	-	NP_001071174;NP_001181966	NM_001077706;NM_001195037	ENSP00000356655	known	0	1	0	Eukaryotes	0	0	Signal transduction	-1	chr6	139134412	139223761	CGC	leukemia
10085	EDIL3	EGF-like repeats and discoidin I-like domains 3	5q14	09350	3173	606018	NP_005702	NM_005711	-	candidate	0	0	0	Eukaryotes	2	1	-1	54	chr5	83239241	83680192	WGS	melanoma
1910	EDNRB	endothelin receptor type B	13q22	08834	3180	131244	NP_003982;NP_000106;NP_001116131;NP_001188326	NM_003991;NM_000115;NM_001122659;NM_001201397	ENSP00000335311;ENSP00000366416;ENSP00000403401	candidate	0	0	0	Metazoans	6	0	Cell cycle,Cell motility and interactions,Cell response to stimuli,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction	88	chr13	78472338	78493750	WES	colorectal (non-hypermutated)
1917	EEF1A2	eukaryotic translation elongation factor 1 alpha 2	20q13.3	04265	3192	602959	NP_001949	NM_001958	ENSP00000217182	known	0	0	24	Last Universal Common Ancestor	58	3	Cell cycle,Cellular metabolism,Development,Regulation of intracellular processes and metabolism,Regulation of transcription	57	chr20	62119654	62129116	CGC,Amplified	
80258	EFHC2	EF-hand domain (C-terminal) containing 2	Xp11.3	06540	26233	300817	NP_079460	NM_025184	ENSP00000333823	candidate	0	0	0	Eukaryotes	6	0	-1	84	chrX	44008044	44202834	WGS	breast
23167	EFR3A	EFR3 homolog A (S. cerevisiae)	8q24.22	17179	28970	611798	NP_055952	NM_015137	ENSP00000254624	candidate	0	0	0	Eukaryotes	1	2	-1	98	chr8	132952742	133023139	WGS	chronic lymphocytic leukemia
133584	EGFLAM	EGF-like, fibronectin type III and laminin G domains	5p13.2-p13.1	13433	26810	-	NP_877953;NP_001192230;NP_689616;NP_877950	NM_182801;NM_182799;NM_001205301;NM_152403;NM_182798	ENSP00000346964;ENSP00000313084	candidate	0	0	0	Eukaryotes	2	1	-1	-1	chr5	38258857	38464085	WES	pancreas
1956	EGFR	epidermal growth factor receptor	7p12	00579	3236	131550	NP_958439;NP_958441;NP_005219;NP_958440	NM_201282;NM_201284;NM_005228;NM_201283	ENSP00000342376;ENSP00000413843;ENSP00000345973	known	1	0	0	Last Universal Common Ancestor	483	21	Cell cycle,Cell motility and interactions,Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction	94	chr7	55086971	55273307	CGC,HTMS,WES,Amplified	glioma,lung,breast,glioblastoma,ovarian,pancreas,prostate
1959	EGR2	early growth response 2	10q21.1	00551	3239	129010	NP_000390;NP_001129650;NP_001129651;NP_001129649	NM_000399;NM_001136178;NM_001136179;NM_001136177	ENSP00000242480;ENSP00000402040;ENSP00000387634	candidate	0	0	0	Last Universal Common Ancestor	18	7	Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription	26	chr10	64572970	64575789	WES	chronic lymphocytic leukemia
23741	EID1	EP300 interacting inhibitor of differentiation 1	15q21.1	06907	1191	605894	NP_055150	NM_014335	ENSP00000431162	candidate	0	0	0	-	43	2	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	102	chr15	49170374	49170934	WGS	liver
8661	EIF3A	eukaryotic translation initiation factor 3, subunit A	10q26	03618	3271	602039	NP_003741	NM_003750	ENSP00000358140	candidate	0	0	0	Last Universal Common Ancestor	78	3	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	106	chr10	120795554	120840188	WES	gastric
8667	EIF3H	eukaryotic translation initiation factor 3, subunit H	8q24.11	04885	3273	603912	NP_003747	NM_003756	-	candidate	0	0	0	Eukaryotes	52	2	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	109	chr8	117657248	117768036	HTMS	breast,lung,ovarian,pancreas,prostate
1974	EIF4A2	eukaryotic translation initiation factor 4A2	3q28	03062	3284	601102	NP_001958	NM_001967	ENSP00000326381	known	1	0	11	Last Universal Common Ancestor	74	2	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	109	chr3	186502219	186507055	CGC	non-hodgkin lymphoma
1984	EIF5A	eukaryotic translation initiation factor 5A	17p13-p12	02555	3300	600187	NP_001137234;NP_001137233;NP_001137232;NP_001961	NM_001143762;NM_001143761;NM_001143760;NM_001970	ENSP00000336702;ENSP00000390677;ENSP00000396073;ENSP00000336776	candidate	0	0	4	Last Universal Common Ancestor	25	0	Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Other,Regulation of intracellular processes and metabolism,Regulation of transcription	107	chr17	7210366	7214956	WGS	lymphoma
56648	EIF5A2	eukaryotic translation initiation factor 5A2	3q26.2	10426	3301	605782	NP_065123	NM_020390	ENSP00000295822	known	0	0	4	Last Universal Common Ancestor	29	4	Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription	13	chr3	170611152	170625595	CGC,Amplified	
1993	ELAVL2	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)	9p21	03396	3313	601673	NP_004423;NP_001164668;NP_001164666	NM_004432;NM_001171197;NM_001171195	ENSP00000369453;ENSP00000380479	candidate	0	0	2	Last Universal Common Ancestor	11	4	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	19	chr9	23692558	23762232	WES	lung
2000	ELF4	E74-like factor 4 (ets domain transcription factor)	Xq26	06499	3319	300775	NP_001412;NP_001120669	NM_001421;NM_001127197	ENSP00000338608;ENSP00000311280	known	1	0	0	Metazoans	17	4	Cellular metabolism,DNA/RNA metabolism and transcription,Immune system response,Regulation of intracellular processes and metabolism,Regulation of transcription	32	chrX	129200699	129215304	CGC	leukemia
2005	ELK4	ELK4, ETS-domain protein (SRF accessory protein 1)	1q32	02592	3326	600246	NP_001964;NP_068567	NM_001973;NM_021795	ENSP00000350681	known	1	0	0	Vertebrates	9	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	24	chr1	205585677	205593010	CGC	prostate
8178	ELL	elongation factor RNA polymerase II	19p13.1	02615	23114	600284	NP_006523	NM_006532	ENSP00000262809	known	1	0	0	Metazoans	12	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	37	chr19	18555565	18632865	CGC	leukemia
9844	ELMO1	engulfment and cell motility 1	7p14.1	12102	16286	606420	NP_001193409;NP_001193411;NP_055615;NP_001034548	NR_038121;NM_001206480;NM_001206482;NM_130442;NM_014800;NR_038120;NM_001039459	-	candidate	0	0	0	Eukaryotes	5	0	Cell cycle,Cellular processes,Signal transduction	59	chr7	36895159	37382294	WES	liver
2006	ELN	elastin	7q11.23	00556	3327	130160	NP_001075222;NP_001075224;NP_001075223;NP_001075221;NP_000492	NM_001081753;NM_001081755;NM_001081754;NM_001081752;NM_000501	ENSP00000252034;ENSP00000369949;ENSP00000391129;ENSP00000349540;ENSP00000369950	known	1	0	0	Mammals	24	0	DNA/RNA metabolism and transcription,Development,Multicellular activities	28	chr7	73449693	73483027	CGC,WES	leukemia,pancreas
79071	ELOVL6	ELOVL fatty acid elongase 6	4q25	13269	15829	611546	NP_001124193;NP_076995	NM_001130721;NM_024090	ENSP00000304736	candidate	0	0	0	Eukaryotes	1	1	Cellular metabolism	63	chr4	110972497	111119491	WGS	chronic lymphocytic leukemia
26610	ELP4	elongation protein 4 homolog (S. cerevisiae)	11p13	07377	1171	606985	NP_061913	NM_019040	ENSP00000298937	candidate	0	0	0	Eukaryotes	6	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	63	chr11	31531332	31805069	HTMS	breast,lung,ovarian,pancreas,prostate
27436	EML4	echinoderm microtubule associated protein like 4	2p21	06310	1316	607442	NP_061936;NP_001138548	NM_019063;NM_001145076	ENSP00000320663	known	1	0	0	Last Universal Common Ancestor	18	5	Cell cycle,Cellular processes	63	chr2	42472644	42557344	CGC	lung
2019	EN1	engrailed homeobox 1	2q14.2	08835	3342	131290	NP_001417	NM_001426	ENSP00000295206	candidate	0	0	0	Eukaryotes	4	0	Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription	22	chr2	119600517	119604743	WGS	lung
387712	ENO4	enolase family member 4	10q25.3	-	31670	-	NP_001229628	NM_001242699	ENSP00000345555	candidate	0	0	0	Last Universal Common Ancestor	0	0	-1	-1	chr10	118609078	118641177	WGS	lung
2033	EP300	E1A binding protein p300	22q13.2	04078	3373	602700	NP_001420	NM_001429	ENSP00000263253	known	0	1	0	Eukaryotes	406	11	Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	77	chr22	41489009	41574957	CGC,WES	breast,colorectal,leukemia,lymphoma,pancreas,bladder
23136	EPB41L3	erythrocyte membrane protein band 4.1-like 3	18p11.32	05622	3380	605331	NP_036439	NM_012307	ENSP00000343158	candidate	0	0	0	Metazoans	18	1	Cellular processes	72	chr18	5394685	5489182	WES	gastric
80314	EPC1	enhancer of polycomb homolog 1 (Drosophila)	10p11	09941	19876	610999	NP_079485	NM_025209	ENSP00000263062	candidate	0	0	0	Eukaryotes	19	7	Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	-1	chr10	32557994	32635843	WES	pancreas
57724	EPG5	ectopic P-granules autophagy protein 5 homolog (C. elegans)	18q12.3	11157	29331	-	NP_066015	NM_020964	ENSP00000282041	candidate	0	0	0	Eukaryotes	21	0	-1	-1	chr18	43432435	43547205	WES	breast,chronic lymphocytic leukemia
2041	EPHA1	EPH receptor A1	7q34	01554	3385	179610	NP_005223	NM_005232	ENSP00000275815	candidate	0	0	0	Last Universal Common Ancestor	1	1	Cellular metabolism,Cellular processes,Signal transduction	36	chr7	143088553	143105898	HTMS	sarcoma
2042	EPHA3	EPH receptor A3	3p11.2	01555	3387	179611	NP_872585;NP_005224	NM_182644;NM_005233	ENSP00000337451;ENSP00000399926	candidate	0	0	0	Last Universal Common Ancestor	7	0	Cellular metabolism,Cellular processes,Signal transduction	27	chr3	89156899	89528649	HTMS,WES	lung,colorectal
2043	EPHA4	EPH receptor A4	2q36.1	03719	3388	602188	NP_004429	NM_004438	ENSP00000281821	candidate	0	0	0	Last Universal Common Ancestor	7	6	Cellular metabolism,Cellular processes,Signal transduction	21	chr2	222290751	222436968	WGS	chronic lymphocytic leukemia
2044	EPHA5	EPH receptor A5	4q13.1	02474	3389	600004	NP_004430;NP_872272	NM_004439;NM_182472	ENSP00000273854	candidate	0	0	0	Last Universal Common Ancestor	0	2	Cellular metabolism,Cellular processes,Signal transduction	46	chr4	66189835	66535460	HTMS	breast,lung,ovarian,pancreas,prostate,sarcoma
2045	EPHA7	EPH receptor A7	6q16.1	03721	3390	602190	NP_004431	NM_004440	ENSP00000358309	candidate	0	0	0	Last Universal Common Ancestor	13	3	Cellular metabolism,Cellular processes,Signal transduction	10	chr6	93953147	94129059	HTMS,WES	sarcoma,head and neck squamous cell carcinoma,prostate
2047	EPHB1	EPH receptor B1	3q21-q23	02790	3392	600600	NP_004432	NM_004441	ENSP00000381097	candidate	0	0	0	Last Universal Common Ancestor	5	0	Cellular metabolism,Cellular processes,Development,Signal transduction	49	chr3	134514474	134977959	HTMS,WES	breast,lung,ovarian,pancreas,prostate,chronic lymphocytic leukemia
2050	EPHB4	EPH receptor B4	7q22	02481	3395	600011	NP_004435	NM_004444	ENSP00000350896	candidate	0	0	0	Last Universal Common Ancestor	2	1	Cellular metabolism,Cellular processes,Development,Signal transduction	77	chr7	100401086	100424652	WGS	melanoma
2051	EPHB6	EPH receptor B6	7q33-q35	04133	3396	602757	NP_004436	NM_004445	ENSP00000376684	candidate	0	0	0	Last Universal Common Ancestor	5	0	Cellular metabolism,Cellular processes,Signal transduction	71	chr7	142560986	142568654	WES	colorectal
2060	EPS15	epidermal growth factor receptor pathway substrate 15	1p32	08968	3419	600051	NP_001153441;NP_001972	NM_001159969;NM_001981	ENSP00000360798	known	1	0	0	Eukaryotes	133	0	Cellular processes,Signal transduction	94	chr1	51822375	51946995	CGC	leukemia
2064	ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	17q11.2-q12|17q21.1	01281	3430	164870	NP_001005862;NP_004439	NM_001005862;NM_004448	ENSP00000385185;ENSP00000269571	known	1	0	0	Last Universal Common Ancestor	106	15	Cell cycle,Cell motility and interactions,Cellular metabolism,Cellular processes,Development,Immune system response,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction	71	chr17	37856492	37884294	CGC,HTMS,WES,WGS,Amplified	breast,gastric,lung,other,ovarian,glioblastoma
55914	ERBB2IP	erbb2 interacting protein	5q12.3	06090	15842	606944	NP_001240630;NP_001240628;NP_001240627;NP_001006600;NP_001240626;NP_061165	NM_001253701;NM_001253699;NM_001253698;NM_001006600;NM_001253697;NM_018695	ENSP00000370322;ENSP00000284037;ENSP00000370330	candidate	0	0	0	Last Universal Common Ancestor	38	9	Cell cycle,Cellular processes,Development,Signal transduction	83	chr5	65288547	65374355	WES	lymphoma
2065	ERBB3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)	12q13	01820	3431	190151	NP_001973;NP_001005915	NM_001982;NM_001005915	ENSP00000415753;ENSP00000267101	candidate	0	0	0	Last Universal Common Ancestor	53	6	Cell cycle,Cell motility and interactions,Cellular metabolism,Cellular processes,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction	89	chr12	56474085	56495836	HTMS,WES	breast,lung,ovarian,pancreas,prostate,bladder
2066	ERBB4	v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)	2q33.3-q34	02767	3432	600543	NP_001036064;NP_005226	NM_001042599;NM_005235	ENSP00000403204;ENSP00000342235	candidate	0	0	0	Last Universal Common Ancestor	71	4	Cellular metabolism,Cellular processes,Signal transduction	83	chr2	212248343	213403254	HTMS	breast,lung,ovarian,pancreas,prostate,sarcoma
23085	ERC1	ELKS/RAB6-interacting/CAST family member 1	12p13.3	06181	17072	607127	NP_829884;NP_829883	NR_027946;NR_027948;NM_178040;NR_027949;NM_178039	ENSP00000468263	known	1	0	0	Last Universal Common Ancestor	8	5	Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	93	chr12	1137070	1599393	CGC	thyroid
26059	ERC2	ELKS/RAB6-interacting/CAST family member 2	3p14.3	10810	31922	-	NP_056391	NM_015576	ENSP00000288221	candidate	0	0	0	Last Universal Common Ancestor	6	0	-1	27	chr3	55733406	56469035	WGS	liver
2068	ERCC2	excision repair cross-complementing rodent repair deficiency, complementation group 2	19q13.3	00530	3434	126340	NP_001124339;NP_000391	NM_001130867;NM_000400	ENSP00000375808;ENSP00000431229	known	0	1	0	Last Universal Common Ancestor	24	0	Cell cycle,Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription	4	chr19	45854890	45873489	CGC	
2071	ERCC3	excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing)	2q21	00593	3435	133510	NP_000113	NM_000122	ENSP00000285398	known	0	1	0	Last Universal Common Ancestor	38	2	Cell cycle,Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription	38	chr2	128015175	128051295	CGC	
2072	ERCC4	excision repair cross-complementing rodent repair deficiency, complementation group 4	16p13.12	00594	3436	133520	NP_005227	NM_005236	ENSP00000310520	known	0	1	0	Last Universal Common Ancestor	25	1	Cell response to stimuli,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	48	chr16	14014023	14042201	CGC	
2073	ERCC5	excision repair cross-complementing rodent repair deficiency, complementation group 5	13q33	00595	3437	133530	NP_000114	NM_000123	ENSP00000347978	known	0	1	0	Last Universal Common Ancestor	23	3	Cell cycle,Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism	58	chr13	103498617	103528250	CGC,WGS	melanoma
2074	ERCC6	excision repair cross-complementing rodent repair deficiency, complementation group 6	10q11.23	00596	3438	609413	NP_000115	NM_000124	ENSP00000348089	candidate	0	0	0	Last Universal Common Ancestor	44	0	Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	93	chr10	50666864	50741010	WES	colorectal,gastric
2078	ERG	v-ets erythroblastosis virus E26 oncogene homolog (avian)	21q22.3	01298	3446	165080	NP_891548;NP_001129626;NP_004440;NP_001230357;NP_001230358;NP_001129627;NP_001230361	NM_182918;NM_001136154;NM_001243433;NM_004449;NM_001243428;NM_001243429;NM_001136155;NM_001243432	ENSP00000414150;ENSP00000381871;ENSP00000394694;ENSP00000288319	known	1	0	0	Metazoans	44	2	Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	61	chr21	39755328	39947624	CGC	leukemia,prostate,sarcoma
54206	ERRFI1	ERBB receptor feedback inhibitor 1	1p36	09218	18185	608069	NP_061821	NM_018948	ENSP00000366702	candidate	0	0	0	Eukaryotes	11	1	-1	-1	chr1	8073273	8075679	WGS	liver
9700	ESPL1	extra spindle pole bodies homolog 1 (S. cerevisiae)	12q	06825	16856	604143	NP_036423	NM_012291	ENSP00000257934	candidate	0	0	0	Eukaryotes	9	4	Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism	56	chr12	53662551	53687255	WES	bladder
2113	ETS1	v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)	11q23.3	01260	3488	164720	NP_001137292;NP_001155894;NP_005229	NM_001143820;NM_001162422;NM_005238	ENSP00000376436;ENSP00000441430	candidate	0	0	0	Metazoans	104	9	Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription	31	chr11	128332259	128443025	HTMS,WES	breast,lung,ovarian,pancreas,prostate,non-hodgkin lymphoma
2115	ETV1	ets variant 1	7p21.3	02765	3490	600541	NP_001156624;NP_001156623;NP_001156621;NP_001156620;NP_001156622;NP_004947;NP_001156619	NM_001163152;NM_001163151;NM_001163149;NM_001163148;NM_001163150;NM_004956;NM_001163147	ENSP00000242066;ENSP00000340853;ENSP00000411626;ENSP00000382293;ENSP00000405327	known	1	0	0	Metazoans	22	1	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	89	chr7	13935494	14028677	CGC,Amplified	prostate,sarcoma
2118	ETV4	ets variant 4	17q21	02833	3493	600711	NP_001073143;NP_001977	NM_001079675;NM_001986	ENSP00000321835;ENSP00000443846;ENSP00000377273	known	1	0	0	Metazoans	15	1	Cell cycle,Cell motility and interactions,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription	11	chr17	41605890	41622985	CGC	prostate,sarcoma
2119	ETV5	ets variant 5	3q28	09035	3494	601600	NP_004445	NM_004454	ENSP00000306894	known	1	0	0	Metazoans	16	1	Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription	79	chr3	185766431	185823657	CGC,WGS	prostate,melanoma
2120	ETV6	ets variant 6	12p13	15976	3495	600618	NP_001978	NM_001987	-	known	1	0	0	Metazoans	26	1	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	13	chr12	11905384	12043977	CGC,WES	breast,leukemia,lymphoma,myelodysplasia,sarcoma
2125	EVPL	envoplakin	17q25	03352	3503	601590	NP_001979	NM_001988	ENSP00000301607	candidate	0	0	0	Eukaryotes	19	0	Cellular metabolism,Cellular processes,Development	4	chr17	74003187	74023279	WES	pancreas
2130	EWSR1	Ewing sarcoma breakpoint region 1	22q12.2	00592	3508	133450	NP_053733;NP_001156759;NP_005234;NP_001156758;NP_001156757	NM_013986;NM_001163287;NM_005243;NM_001163286;NM_001163285	ENSP00000385726;ENSP00000327456;ENSP00000381031;ENSP00000400142	known	1	0	1	Eukaryotes	333	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	109	chr22	29668370	29696148	CGC	desmoplastic small round cell tumor,leukemia,myoepithelioma,sarcoma
55763	EXOC1	exocyst complex component 1	4q12	07615	30380	607879	NP_060731;NP_839955;NP_001020095	NM_018261;NM_178237;NM_001024924	ENSP00000370695;ENSP00000326514;ENSP00000334431	candidate	0	0	0	Eukaryotes	40	0	Cellular processes	102	chr4	56724490	56770658	WGS	melanoma
55770	EXOC2	exocyst complex component 2	6p25.3	11544	24968	-	NP_060773	NM_018303	ENSP00000230449	candidate	0	0	0	Eukaryotes	18	3	Cellular processes	23	chr6	486674	637818	HTMS	breast,lung,ovarian,pancreas,prostate
60412	EXOC4	exocyst complex component 4	7q31	12185	30389	608185	NP_001032203;NP_068579	NM_001037126;NM_021807	ENSP00000376868;ENSP00000253861	candidate	0	0	0	Eukaryotes	31	1	Cellular processes	-1	chr7	132937858	133749278	WES	colorectal
149371	EXOC8	exocyst complex component 8	1q42.2	09943	24659	-	NP_787072	NM_175876	ENSP00000353564	candidate	0	0	0	Eukaryotes	36	1	Cellular processes	-1	chr1	231471317	231473491	WES	pancreas
23086	EXPH5	exophilin 5	11q22.3	08341	30578	612878	NP_055880	NM_001144763;NM_001144765;NM_015065	ENSP00000265843	candidate	0	0	0	Mammals	3	0	Cellular processes	87	chr11	108380267	108464263	WES	pancreas
2131	EXT1	exostosin 1	8q24.11	00598	3512	608177	NP_000118	NM_000127	-	known	0	1	0	Eukaryotes	6	1	Cell cycle,Cellular metabolism,Development,Regulation of intracellular processes and metabolism,Signal transduction	87	chr8	118811954	119123285	CGC	
2132	EXT2	exostosin 2	11p12-p11	00599	3513	608210	NP_997005;NP_001171554;NP_000392	NM_207122;NM_001178083;NM_000401	ENSP00000379032;ENSP00000351509;ENSP00000431173	known	0	1	0	Eukaryotes	34	1	Cell cycle,Cellular metabolism,Development,Regulation of intracellular processes and metabolism,Signal transduction	91	chr11	44117803	44265834	CGC,HTMS	breast,lung,ovarian,pancreas,prostate
2070	EYA4	eyes absent homolog 4 (Drosophila)	6q23	04648	3522	603550	NP_004091;NP_742101;NP_742103	NM_004100;NM_172103;NM_172105;NM_172104	ENSP00000356870;ENSP00000347294	candidate	0	0	0	Eukaryotes	1	12	Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	20	chr6	133595919	133849940	WES	colorectal
346007	EYS	eyes shut homolog (Drosophila)	6q12	16853	21555	612424	NP_938024;NP_001136273;NP_001136272	NM_198283;NM_001142801;NM_001142800	ENSP00000424243;ENSP00000377042;ENSP00000341818	candidate	0	0	0	Last Universal Common Ancestor	0	3	-1	-1	chr6	64430495	66205303	HTMS	breast,lung,ovarian,pancreas,prostate
2146	EZH2	enhancer of zeste homolog 2 (Drosophila)	7q35-q36	03342	3527	601573	NP_001190178;NP_001190177;NP_694543;NP_004447;NP_001190176	NM_001203249;NM_001203248;NM_152998;NM_004456;NM_001203247	ENSP00000419711;ENSP00000419856;ENSP00000419050;ENSP00000320147;ENSP00000223193	known	0	1	0	Last Universal Common Ancestor	128	15	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	19	chr7	148504741	148544390	CGC,WES	lymphoma,leukemia,myelodysplasia,non-hodgkin lymphoma
7430	EZR	ezrin	6q25.3	00475	12691	123900	NP_003370;NP_001104547	NM_003379;NM_001111077	ENSP00000356042;ENSP00000338934	known	1	0	0	Eukaryotes	109	3	Cell motility and interactions,Cellular processes,Development,Regulation of intracellular processes and metabolism	105	chr6	159187949	159210403	CGC	lung
2162	F13A1	coagulation factor XIII, A1 polypeptide	6p25.3-p24.3	00604	3531	134570	NP_000120	NM_000129	ENSP00000264870	candidate	0	0	0	Metazoans	24	0	Cellular metabolism,Cellular processes,Multicellular activities	95	chr6	6145855	6318897	WGS	chronic lymphocytic leukemia
2151	F2RL2	coagulation factor II (thrombin) receptor-like 2	5q13	03561	3539	601919	NP_004092	NM_004101	ENSP00000296641	candidate	0	0	0	Vertebrates	16	0	Multicellular activities,Signal transduction	17	chr5	75913410	75919055	WGS	melanoma
2157	F8	coagulation factor VIII, procoagulant component	Xq28	02384	3546	300841	NP_000123;NP_063916	NM_000132;NM_019863	ENSP00000353393;ENSP00000327895	candidate	0	0	0	Eukaryotes	27	0	Cell response to stimuli,Immune system response,Multicellular activities	89	chrX	154065875	154250827	WES	colorectal,pancreas
158584	FAAH2	fatty acid amide hydrolase 2	Xp11.21	06551	26440	300654	NP_777572	NM_174912	ENSP00000364035	candidate	0	0	0	Last Universal Common Ancestor	1	1	-1	-1	chrX	57313259	57515362	WES	head and neck squamous cell carcinoma
8772	FADD	Fas (TNFRSF6)-associated via death domain	11q13.3	03909	3573	602457	NP_003815	NM_003824	ENSP00000301838	known	0	0	0	Metazoans	66	6	Cell cycle,Development,Regulation of intracellular processes and metabolism,Signal transduction	32	chr11	70049566	70052576	CGC,Amplified	
83641	FAM107B	family with sequence similarity 107, member B	10p13	12575	23726	-	NP_113641	NM_031453	ENSP00000181796	candidate	0	0	0	Metazoans	3	1	-1	-1	chr10	14563192	14816662	WGS	breast
374393	FAM111B	family with sequence similarity 111, member B	11q12.1	07096	24200	-	NP_945185;NP_001136176;NP_001136175	NM_198947;NM_001142704;NM_001142703	ENSP00000393855;ENSP00000341565	candidate	0	0	0	Eukaryotes	3	1	-1	-1	chr11	58877099	58893772	WES	kidney
81558	FAM117A	family with sequence similarity 117, member A	17q21.33	17432	24179	-	NP_110429	NM_030802	ENSP00000240364	candidate	0	0	0	Metazoans	0	0	-1	105	chr17	47788620	47841449	WES	chronic lymphocytic leukemia
139285	FAM123B	family with sequence similarity 123B	Xq11.2	06565	26837	300647	NP_689637	NM_152424	ENSP00000329117	known	0	1	0	Vertebrates	7	1	-1	-1	chrX	63409762	63413166	CGC,WES	Wilms,colorectal (non-hypermutated)
388581	FAM132A	family with sequence similarity 132, member A	1p36.33	-	32308	-	NP_001014980	NM_001014980	ENSP00000329137	candidate	0	0	0	Metazoans	0	0	-1	-1	chr1	1177931	1182070	WGS	glioblastoma
286499	FAM133A	family with sequence similarity 133, member A	Xq21.32	06562	26748	-	NP_001164582;NP_001164580;NP_001164581;NP_775969	NM_001171111;NM_001171109;NM_001171110;NM_173698	ENSP00000348067;ENSP00000441389;ENSP00000318974;ENSP00000362169	candidate	0	0	3	Eukaryotes	0	3	-1	-1	chrX	92964419	92965162	WES	lung
51059	FAM135B	family with sequence similarity 135, member B	8q24.23	14230	28029	-	NP_056996	NM_015912	ENSP00000378710	candidate	0	0	0	Eukaryotes	2	0	-1	-1	chr8	139144839	139380226	WES	head and neck squamous cell carcinoma
10144	FAM13A	family with sequence similarity 13, member A	4q22.1	10944	19367	613299	NP_001015045;NP_055698	NM_001015045;NM_014883	ENSP00000378450;ENSP00000264344	candidate	0	0	0	Eukaryotes	0	0	Signal transduction	95	chr4	89649687	89950800	WGS	liver
220965	FAM13C	family with sequence similarity 13, member C	10q21.1	16875	19371	-	NP_001001971;NP_001160170;NP_937858;NP_001137245	NM_001001971;NM_001166698;NM_198215;NM_001143773	ENSP00000391993;ENSP00000362974;ENSP00000362975	candidate	0	0	0	Metazoans	2	0	-1	4	chr10	61007377	61122220	WGS	glioblastoma
57700	FAM160B1	family with sequence similarity 160, member B1	10q25.3	17219	29320	-	NP_001128523;NP_065991	NM_001135051;NM_020940	ENSP00000358253;ENSP00000358251	candidate	0	0	0	Eukaryotes	3	1	-1	-1	chr10	116581838	116621296	WGS	lung
84140	FAM161A	family with sequence similarity 161, member A	2p15	-	25808	613596	NP_001188472;NP_115556	NM_001201543;NR_037710;NM_032180	ENSP00000385158;ENSP00000385893	candidate	0	0	0	Eukaryotes	2	0	-1	-1	chr2	62053593	62081176	WES	colorectal
221061	FAM171A1	family with sequence similarity 171, member A1	10p13	18581	23522	-	NP_001010924	NM_001010924	ENSP00000367356	candidate	0	0	0	Vertebrates	11	6	-1	97	chr10	15254917	15413051	WGS	chronic lymphocytic leukemia
165215	FAM171B	family with sequence similarity 171, member B	2q32.1	13907	29412	-	NP_803237	NM_177454	-	candidate	0	0	0	Vertebrates	2	5	-1	-1	chr2	187558901	187627547	WES	breast
8603	FAM193A	family with sequence similarity 193, member A	4p16.3	09850	16822	-	NP_003695	NM_003704	ENSP00000324587;ENSP00000427505;ENSP00000421200;ENSP00000372290	candidate	0	0	0	Metazoans	0	1	-1	96	chr4	2632732	2733592	WGS	prostate
54540	FAM193B	family with sequence similarity 193, member B	5q35.3	07671	25524	-	NP_001177875	NM_019057;NM_001190946;NR_024019	ENSP00000422131	candidate	0	0	0	Metazoans	13	0	-1	91	chr5	176948979	176981459	WES	colorectal
25817	FAM19A5	family with sequence similarity 19 (chemokine (C-C motif)-like), member A5	22q13.32	13295	21592	-	NP_056196;NP_001076436	NM_015381;NM_001082967	ENSP00000351043	candidate	0	0	0	Vertebrates	0	0	-1	-1	chr22	48885405	49103659	WGS	glioblastoma
728118	FAM22A	family with sequence similarity 22, member A	10q23.2	-	23438	-	NP_001092808	NM_001099338	ENSP00000371126	known	1	0	5	Mammals	3	1	-1	-1	chr10	88985588	88994462	CGC	sarcoma
729262	FAM22B	family with sequence similarity 22, member B	10q22.3	-	23445	-	-	-	-	known	1	0	-1	Mammals	1	1	-1	-1	-	0	0	CGC	sarcoma
728130	FAM22D	family with sequence similarity 22, member D	10q23.2	-	23447	-	NP_001009610	NM_001009610	-	candidate	0	0	6	Mammals	0	1	-1	-1	chr10	89118023	89125562	WGS	glioblastoma
54855	FAM46C	family with sequence similarity 46, member C	1p12	13312	24712	613952	NP_060179	NM_017709	ENSP00000358458	known	0	1	1	Eukaryotes	9	2	-1	40	chr1	118165491	118166663	CGC,WES,WGS	myeloma
55199	FAM86C1	family with sequence similarity 86, member C1	11q13.4	13337	25561	-	NP_001093123;NP_060642;NP_689776	NM_001099653;NM_018172;NM_152563	ENSP00000352182;ENSP00000325662	candidate	0	0	12	Eukaryotes	3	0	-1	13	chr11	71498583	71510690	WGS	lymphoma
339145	FAM92B	family with sequence similarity 92, member B	16q24.1	13488	24781	-	NP_940893	NM_198491	ENSP00000443411	candidate	0	0	0	Vertebrates	0	0	-1	-1	chr16	85132794	85144068	WES	pancreas
2175	FANCA	Fanconi anemia, complementation group A	16q24.3	06186	3582	607139	NP_001018122;NP_000126	NM_001018112;NM_000135	ENSP00000373952;ENSP00000373953	known	0	1	0	Metazoans	16	1	DNA/RNA metabolism and transcription	42	chr16	89805012	89883023	CGC	
2176	FANCC	Fanconi anemia, complementation group C	9q22.3	01967	3584	613899	NP_001230673;NP_000127;NP_001230672	NM_001243744;NM_000136;NM_001243743	ENSP00000289081;ENSP00000364454	known	0	1	0	Metazoans	39	1	DNA/RNA metabolism and transcription	98	chr9	97863992	98011573	CGC	
2177	FANCD2	Fanconi anemia, complementation group D2	3p26	01968	3585	613984	NP_001018125;NP_149075	NM_001018115;NM_033084	ENSP00000373318;ENSP00000287647	known	0	1	0	Eukaryotes	52	1	Cell response to stimuli,DNA/RNA metabolism and transcription	-1	chr3	10070342	10140631	CGC	
2178	FANCE	Fanconi anemia, complementation group E	6p22-p21	02943	3586	613976	NP_068741	NM_021922	ENSP00000229769	known	0	1	0	Eukaryotes	17	1	DNA/RNA metabolism and transcription	48	chr6	35420323	35434119	CGC	
2188	FANCF	Fanconi anemia, complementation group F	11p15	04589	3587	613897	NP_073562	NM_022725	ENSP00000330875	known	0	1	0	Metazoans	21	0	DNA/RNA metabolism and transcription	2	chr11	22646235	22647356	CGC	
2189	FANCG	Fanconi anemia, complementation group G	9p13	04262	3588	602956	NP_004620	NM_004629	ENSP00000367910	known	0	1	0	Last Universal Common Ancestor	46	2	Cell cycle,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Signal transduction	21	chr9	35074108	35079521	CGC	
57697	FANCM	Fanconi anemia, complementation group M	14q21.2	13876	23168	609644	NP_065988	NM_020937	ENSP00000267430	candidate	0	0	0	Last Universal Common Ancestor	42	2	DNA/RNA metabolism and transcription	-1	chr14	45605235	45669208	WGS	glioblastoma
355	FAS	Fas (TNF receptor superfamily, member 6)	10q24.1	00609	11920	134637	NP_690610;NP_690611;NP_000034	NM_152871;NR_028036;NM_152874;NR_028033;NM_152872;NM_152875;NM_152877;NR_028035;NR_028034;NM_152873;NM_000043;NM_152876	ENSP00000347979	known	0	1	0	Last Universal Common Ancestor	94	4	Cell cycle,Development,Regulation of intracellular processes and metabolism,Signal transduction	81	chr10	90762786	90774204	CGC,WES	lymphoma,skin,testis,non-hodgkin lymphoma
2195	FAT1	FAT tumor suppressor homolog 1 (Drosophila)	4q35	02986	3595	600976	NP_005236	NM_005245	ENSP00000406229	candidate	0	0	0	Last Universal Common Ancestor	5	0	Cell motility and interactions,Cellular processes,Development	91	chr4	187509749	187630981	WES	head and neck squamous cell carcinoma
2196	FAT2	FAT tumor suppressor homolog 2 (Drosophila)	5q33.1	05041	3596	604269	NP_001438	NM_001447	ENSP00000261800	candidate	0	0	0	Last Universal Common Ancestor	0	0	Cell motility and interactions	13	chr5	150885129	150948492	WES,WGS	non-hodgkin lymphoma,pancreas,melanoma
120114	FAT3	FAT tumor suppressor homolog 3 (Drosophila)	11q14.3	-	23112	612483	NP_001008781	NM_001008781	ENSP00000387040	candidate	0	0	0	Last Universal Common Ancestor	3	6	Cell motility and interactions	-1	chr11	92085279	92624276	WES,WGS	chronic lymphocytic leukemia,liver
79633	FAT4	FAT tumor suppressor homolog 4 (Drosophila)	4q28.1	07637	23109	612411	NP_078858	NM_024582	ENSP00000377862	candidate	0	0	0	Last Universal Common Ancestor	8	1	Cell motility and interactions	47	chr4	126237567	126412920	WES	gastric
2201	FBN2	fibrillin 2	5q23-q31	00416	3604	612570	NP_001990	NM_001999	ENSP00000262464	candidate	0	0	0	Last Universal Common Ancestor	9	5	Development	49	chr5	127595150	127873296	WES	colorectal
80204	FBXO11	F-box protein 11	2p16.3	06985	13590	607871	NP_079409;NP_001177203	NM_018693;NM_025133;NM_001190274;NM_012167	ENSP00000384823;ENSP00000385398	known	0	1	0	Last Universal Common Ancestor	26	6	Cellular metabolism,Cellular processes	66	chr2	48035260	48132859	CGC,WES,WGS	lymphoma
79791	FBXO31	F-box protein 31	16q24.2	10954	16510	609102	NP_079011	NM_024735;NR_024568	-	candidate	0	0	0	Eukaryotes	7	2	-1	12	chr16	87364897	87417350	WES	lymphoma
114907	FBXO32	F-box protein 32	8q24.13	05966	16731	606604	NP_001229392;NP_680482;NP_478136	NM_001242463;NM_148177;NM_058229	ENSP00000428205	candidate	0	0	0	Metazoans	17	0	-1	-1	chr8	124515616	124553254	HTMS	breast,lung,ovarian,pancreas,prostate
55294	FBXW7	F-box and WD repeat domain containing 7	4q31.3	05888	16712	606278	NP_001013433;NP_060785;NP_361014	NM_001013415;NM_018315;NM_033632	ENSP00000296555;ENSP00000263981;ENSP00000281708	known	0	1	0	Last Universal Common Ancestor	57	12	Cellular metabolism,Cellular processes	47	chr4	153244036	153332955	CGC,HTMS,WES	colorectal,endometrium,leukemia,breast,lung,ovarian,pancreas,prostate,sarcoma,colorectal (non-hypermutated),head and neck squamous cell carcinoma
2205	FCER1A	Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide	1q23	00917	3609	147140	NP_001992	NM_002001	ENSP00000357097	candidate	0	0	0	Eukaryotes	4	0	Cell response to stimuli,Cellular metabolism,Cellular processes,Immune system response,Regulation of intracellular processes and metabolism,Signal transduction	33	chr1	159272155	159277719	HTMS,WES	breast,lung,ovarian,pancreas,prostate,melanoma
2213	FCGR2B	Fc fragment of IgG, low affinity IIb, receptor (CD32)	1q23	06849	3618	604590	NP_001177757;NP_001002273;NP_001002275;NP_003992;NP_001002274	NM_001190828;NM_001002273;NM_001002275;NM_004001;NM_001002274	ENSP00000351497	known	1	0	2	Mammals	24	0	Signal transduction	39	chr1	161633032	161647340	CGC	leukemia
83417	FCRL4	Fc receptor-like 4	1q21	16168	18507	605876	NP_112572	NM_031282	ENSP00000271532	known	1	0	0	Eukaryotes	2	1	-1	-1	chr1	157545317	157559252	CGC	non-hodgkin lymphoma
83416	FCRL5	Fc receptor-like 5	1q21	16169	18508	605877	NP_112571;NP_001182317	NM_031281;NM_001195388	ENSP00000354691	candidate	0	0	0	Eukaryotes	0	0	-1	-1	chr1	157485395	157516988	WES	breast
26998	FETUB	fetuin B	3q27	09335	3658	605954	NP_055190	NM_014375	ENSP00000265029	candidate	0	0	0	Eukaryotes	7	1	-1	62	chr3	186358250	186370417	WGS	lung
54738	FEV	FEV (ETS oncogene family)	2q36	06193	18562	607150	NP_059991	NM_017521	ENSP00000295727	known	1	0	0	Metazoans	0	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	5	chr2	219846392	219849797	CGC	sarcoma
2243	FGA	fibrinogen alpha chain	4q28	00619	3661	134820	NP_000499;NP_068657	NM_000508;NM_021871	ENSP00000306361;ENSP00000385981	candidate	0	0	0	Eukaryotes	11	6	Cellular metabolism,Cellular processes,Development,Multicellular activities,Signal transduction	61	chr4	155505279	155511839	WGS	breast
2245	FGD1	FYVE, RhoGEF and PH domain containing 1	Xp11.21	02373	3663	300546	NP_004454	NM_004463	ENSP00000364277	candidate	0	0	0	Eukaryotes	7	0	Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction	77	chrX	54472545	54521865	WGS	melanoma
152273	FGD5	FYVE, RhoGEF and PH domain containing 5	3p25.1	13322	19117	-	NP_689749	NM_152536	ENSP00000285046	candidate	0	0	0	Eukaryotes	0	0	Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction	-1	chr3	14860579	14974239	WGS	prostate
2260	FGFR1	fibroblast growth factor receptor 1	8p12	00634	3688	136350	NP_075594;NP_056934;NP_001167534;NP_001167535;NP_075598;NP_001167536;NP_075593;NP_001167537;NP_001167538	NM_023106;NM_015850;NM_001174063;NM_001174064;NM_023110;NM_001174065;NM_023111;NM_023105;NM_001174066;NM_023107;NM_001174067;NM_023108;NM_032191;NM_023109	ENSP00000432972;ENSP00000393312;ENSP00000380280;ENSP00000400162	known	1	0	0	Last Universal Common Ancestor	60	7	Cell cycle,Cellular metabolism,Cellular processes,Development,Signal transduction	97	chr8	38271149	38315054	CGC,Amplified	myeloma,non-hodgkin lymphoma
11116	FGFR1OP	FGFR1 oncogene partner	6q27	10392	17012	605392	NP_919410;NP_008976	NM_194429;NM_007045	ENSP00000230248	known	1	0	0	Eukaryotes	23	1	Cell cycle,Regulation of intracellular processes and metabolism	21	chr6	167412901	167453463	CGC	myeloma,non-hodgkin lymphoma
2263	FGFR2	fibroblast growth factor receptor 2	10q26	01492	3689	176943	NP_001138390;NP_001138388;NP_001138391;NP_075259;NP_001138389;NP_001138387;NP_001138385;NP_000132;NP_001138386	NM_022974;NM_001144918;NM_022971;NM_001144916;NM_022975;NM_022973;NM_022976;NM_001144919;NM_022970;NM_023030;NM_001144917;NM_001144915;NM_022972;NM_001144913;NM_000141;NM_001144914;NM_023028	ENSP00000351276;ENSP00000358052;ENSP00000358057;ENSP00000350166;ENSP00000348559;ENSP00000353262	known	1	0	0	Last Universal Common Ancestor	40	2	Cell cycle,Cellular metabolism,Cellular processes,Signal transduction	80	chr10	123239374	123353331	CGC,WES	endometrium,lung,chronic lymphocytic leukemia
2261	FGFR3	fibroblast growth factor receptor 3	4p16.3	00624	3690	134934	NP_075254;NP_000133;NP_001156685	NM_022965;NM_000142;NM_001163213	ENSP00000414914;ENSP00000339824;ENSP00000412903	known	1	0	0	Last Universal Common Ancestor	69	3	Cell cycle,Cell response to stimuli,Cellular metabolism,Cellular processes,Development,Signal transduction	62	chr4	1795662	1808986	CGC,WES,WGS	bladder,lymphoma,myeloma,lung
2264	FGFR4	fibroblast growth factor receptor 4	5q35.1-qter	00625	3691	134935	NP_998812;NP_002002;NP_075252	NM_213647;NM_002011;NM_022963	ENSP00000424960;ENSP00000377254;ENSP00000292408	candidate	0	0	0	Last Universal Common Ancestor	3	0	Cellular metabolism,Cellular processes,Signal transduction	20	chr5	176516604	176524674	HTMS	lung
2271	FH	fumarate hydratase	1q42.1	00652	3700	136850	NP_000134	NM_000143	ENSP00000355518	known	0	1	0	Last Universal Common Ancestor	14	0	Cell cycle,Cellular metabolism,Multicellular activities,Regulation of intracellular processes and metabolism	107	chr1	241661131	241683022	CGC	
85462	FHDC1	FH2 domain containing 1	4q31.3	13888	29363	-	NP_203751	NM_033393	ENSP00000260008	candidate	0	0	0	Eukaryotes	0	6	Cellular processes	-1	chr4	153864210	153897872	WGS	lymphoma
2272	FHIT	fragile histidine triad gene	3p14.2	03096	3701	601153	NP_002003;NP_001159715	NM_002012;NM_001166243	ENSP00000417557;ENSP00000418582	known	1	0	0	Last Universal Common Ancestor	15	0	Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism	63	chr3	59737955	60522695	CGC	salivary
63979	FIGNL1	fidgetin-like 1	7p12.1	10958	13286	-	NP_001036227;NP_071399	NM_001042762;NM_022116	ENSP00000349356;ENSP00000378924	candidate	0	0	0	Last Universal Common Ancestor	3	1	Cellular metabolism,DNA/RNA metabolism and transcription	-1	chr7	50512964	50514985	WGS	prostate
81608	FIP1L1	FIP1 like 1 (S. cerevisiae)	4q12	09646	19124	607686	NP_112179;NP_001128409;NP_001128410	NM_030917;NM_001134937;NM_001134938	ENSP00000351383;ENSP00000302993;ENSP00000336752	known	1	0	0	Eukaryotes	19	1	DNA/RNA metabolism and transcription,Regulation of transcription	29	chr4	54244006	54325613	CGC	idiopathic hypereosinophilic syndrome
2287	FKBP3	FK506 binding protein 3, 25kDa	14q21.2	01743	3719	186947	NP_002004	NM_002013	ENSP00000379374	candidate	0	0	0	Last Universal Common Ancestor	22	2	Cellular metabolism,Cellular processes	97	chr14	45585404	45603659	WGS	glioblastoma
201163	FLCN	folliculin	17p11.2	06278	27310	607273	NP_659434;NP_653207	NM_144997;NM_144606	ENSP00000373821;ENSP00000285071	known	0	1	0	Eukaryotes	7	4	Cell cycle,Regulation of intracellular processes and metabolism	44	chr17	17116972	17131451	CGC	
2313	FLI1	Friend leukemia virus integration 1	11q24.1-q24.3	01901	3749	193067	NP_001161153;NP_002008	NM_001167681;NM_002017	ENSP00000339627;ENSP00000281428	known	1	0	0	Metazoans	17	5	Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription	67	chr11	128628010	128680880	CGC	sarcoma
148231	FLJ25328	uncharacterized LOC148231	19p13.12	08056	-	-	-	NM_152483;NR_024336;NR_024335	-	candidate	0	0	-1	-	0	0	-1	-1	-	0	0	WGS	breast
145788	FLJ27352	uncharacterized LOC145788	15q21.3	-	-	-	NP_001185713	NM_001198784	ENSP00000456337	known	1	0	0	-	0	0	-1	-1	chr15	55710421	55710765	CGC	lymphoma
2316	FLNA	filamin A, alpha	Xq28	02060	3754	300017	NP_001104026;NP_001447	NM_001110556;NM_001456	ENSP00000358866;ENSP00000416926	candidate	0	0	0	Eukaryotes	122	6	Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	109	chrX	153577220	153599613	WES	breast
2317	FLNB	filamin B, beta	3p14.3	04543	3755	603381	NP_001448;NP_001157790;NP_001157791;NP_001157789	NM_001457;NM_001164318;NM_001164319;NM_001164317	ENSP00000420213;ENSP00000415599;ENSP00000351339;ENSP00000295956	candidate	0	0	0	Eukaryotes	27	6	Cellular processes,Development,Signal transduction	90	chr3	57994292	58156486	WES	breast
2318	FLNC	filamin C, gamma	7q32-q35	00018	3756	102565	NP_001120959;NP_001449	NM_001127487;NM_001458	ENSP00000344002;ENSP00000327145	candidate	0	0	0	Eukaryotes	37	2	-1	87	chr7	128470692	128498574	WES,WGS	breast,colorectal,prostate
23768	FLRT2	fibronectin leucine rich transmembrane protein 2	14q24-q32	05312	3761	604807	NP_037363	NM_013231	ENSP00000332879	candidate	0	0	0	Eukaryotes	10	0	-1	81	chr14	86087859	86089838	WGS	chronic lymphocytic leukemia
2322	FLT3	fms-related tyrosine kinase 3	13q12	00635	3765	136351	NP_004110	NM_004119	ENSP00000241453	known	1	0	0	Last Universal Common Ancestor	11	2	Cell cycle,Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction	48	chr13	28578192	28674647	CGC,HTMS,WES,WGS	leukemia,breast,lung,ovarian,pancreas,prostate,acute myeloid leukemia
56776	FMN2	formin 2	1q43	10449	14074	606373	NP_064450	NM_020066	ENSP00000318884	candidate	0	0	0	Eukaryotes	18	0	Cell cycle,Cellular processes,DNA/RNA metabolism and transcription,Development,Multicellular activities	-1	chr1	240255410	240635753	WES,WGS	gastric,kidney,pancreas,lymphoma
91010	FMNL3	formin-like 3	12q13.12	17007	23698	-	NP_944489;NP_783863	NM_198900;NM_175736	ENSP00000335655	candidate	0	0	0	Eukaryotes	4	3	Cellular processes	-1	chr12	50039601	50100963	WES	pancreas
2335	FN1	fibronectin 1	2q34	00626	3778	135600	NP_997647;NP_997643;NP_997641;NP_002017;NP_473375;NP_997639	NM_212482;NM_212478;NM_212476;NM_002026;NM_054034;NM_212474;NM_212475	ENSP00000338200;ENSP00000398907;ENSP00000350534;ENSP00000348285;ENSP00000410422;ENSP00000346839	candidate	0	0	0	Last Universal Common Ancestor	512	3	Cell motility and interactions,Cell response to stimuli,Immune system response,Signal transduction	97	chr2	216226281	216300525	WES	colorectal
23048	FNBP1	formin binding protein 1	9q34	10446	17069	606191	NP_055848	NM_015033	ENSP00000413625	known	1	0	0	Eukaryotes	34	7	Cellular processes	102	chr9	132658118	132757237	CGC	leukemia
3169	FOXA1	forkhead box A1	14q12-q13	03801	5021	602294	NP_004487	NM_004496	ENSP00000250448	candidate	0	0	0	Opisthokonts	1	3	Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription	49	chr14	38060573	38064177	WES	prostate
3170	FOXA2	forkhead box A2	20p11	02618	5022	600288	NP_710141;NP_068556	NM_153675;NM_021784	ENSP00000315955;ENSP00000366319	candidate	0	0	0	Opisthokonts	0	1	Cellular metabolism,DNA/RNA metabolism and transcription,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription	38	chr20	22562491	22564916	WGS	lymphoma
2304	FOXE1	forkhead box E1 (thyroid transcription factor 2)	9q22	06188	3806	602617	NP_004464	NM_004473	ENSP00000364265	candidate	0	0	0	Eukaryotes	1	1	Cell motility and interactions,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription	17	chr9	100616197	100617315	WES	lung
2299	FOXI1	forkhead box I1	5q34	03057	3815	601093	NP_036320;NP_658982	NM_012188;NM_144769	ENSP00000304286;ENSP00000415483	candidate	0	0	0	Eukaryotes	2	1	Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription	35	chr5	169532962	169535612	WGS	breast
668	FOXL2	forkhead box L2	3q23	05723	1092	605597	NP_075555	NM_023067	ENSP00000333188	known	1	0	0	Eukaryotes	5	0	Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	13	chr3	138664437	138665564	CGC	ovarian
2308	FOXO1	forkhead box O1	13q14.1	00645	3819	136533	NP_002006	NM_002015	ENSP00000368880	known	1	0	0	Eukaryotes	51	12	Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	98	chr13	41133663	41240349	CGC,WES,WGS	sarcoma,non-hodgkin lymphoma,lymphoma
2309	FOXO3	forkhead box O3	6q21	04061	3821	602681	NP_963853;NP_001446	NM_201559;NM_001455	ENSP00000385824;ENSP00000339527	known	1	0	1	Eukaryotes	22	10	Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription	108	chr6	108882412	108986055	CGC	leukemia
4303	FOXO4	forkhead box O4	Xq13.1	02070	7139	300033	NP_001164402;NP_005929	NM_001170931;NM_005938	ENSP00000363377	known	1	0	0	Eukaryotes	22	1	Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	27	chrX	70316379	70321589	CGC	leukemia
27086	FOXP1	forkhead box P1	3p14.1	18518	3823	605515	NP_001231737;NP_001231745;NP_001012523;NP_001231742;NP_001231739;NP_001231743;NP_001231741;NP_116071;NP_001231744	NM_001244808;NM_001244816;NM_001012505;NM_001244813;NM_001244810;NM_001244814;NM_001244812;NM_032682;NM_001244815	ENSP00000318721;ENSP00000318902	known	1	0	0	Metazoans	14	7	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	-1	chr3	71008401	71247532	CGC	leukemia
80020	FOXRED2	FAD-dependent oxidoreductase domain containing 2	22q12.3	08666	26264	613777	NP_001095841;NP_079231	NM_001102371;NM_024955	ENSP00000380401	candidate	0	0	0	Last Universal Common Ancestor	7	3	-1	3	chr22	36886058	36902469	WGS	lung
80144	FRAS1	Fraser syndrome 1	4q21.21	06382	19185	607830	NP_079350;NP_001159605	NM_025074;NM_032863;NM_206841;NM_020875;NM_001166133	ENSP00000326330	candidate	0	0	0	Last Universal Common Ancestor	1	3	-1	51	chr4	78979164	79462275	WGS	melanoma
158326	FREM1	FRAS1 related extracellular matrix 1	9p22.3	09865	23399	608944	NP_001171175;NP_659403	NM_001177704;NM_144966	ENSP00000412940	candidate	0	0	0	Last Universal Common Ancestor	3	1	-1	-1	chr9	14737397	14868975	WES	breast
341640	FREM2	FRAS1 related extracellular matrix protein 2	13q13.3	10602	25396	608945	NP_997244	NM_207361	ENSP00000280481	candidate	0	0	0	Last Universal Common Ancestor	8	1	Cell motility and interactions	-1	chr13	39261482	39454921	WGS	acute myeloid leukemia,lymphoma,prostate
100288801	FRG2C	FSHD region gene 2 family, member C	3p12.3	-	33626	-	NP_001118231	NM_001124759	ENSP00000312299	candidate	0	0	3	Mammals	0	0	-1	-1	chr3	75713531	75715189	WGS	lymphoma
9758	FRMPD4	FERM and PDZ domain containing 4	Xp22.2	10011	29007	300838	NP_055543	NM_014728	ENSP00000370057	candidate	0	0	0	Metazoans	5	0	-1	16	chrX	12157091	12736908	WES	glioblastoma
10818	FRS2	fibroblast growth factor receptor substrate 2	12q15	06372	16971	607743	NP_006645;NP_001036020	NM_006654;NM_001042555	ENSP00000381083;ENSP00000299293	candidate	0	0	0	Eukaryotes	29	9	Cell cycle,Cellular metabolism,Cellular processes,Development,Other,Regulation of intracellular processes and metabolism,Signal transduction	6	chr12	69962811	69968732	HTMS	breast,lung,ovarian,pancreas,prostate
84075	FSCB	fibrous sheath CABYR binding protein	14q21.2	12638	20494	611779	NP_115511	NM_032135	ENSP00000344579	candidate	0	0	0	Last Universal Common Ancestor	0	2	-1	-1	chr14	44973716	44976190	WES	breast,gastric
401024	FSIP2	fibrous sheath interacting protein 2	2q32.1	13483	21675	-	NP_775922	NM_173651;NM_207482	ENSP00000344403	candidate	0	0	0	Mammals	1	0	-1	-1	chr2	186603355	186697950	WGS	chronic lymphocytic leukemia
10272	FSTL3	follistatin-like 3 (secreted glycoprotein)	19p13	05632	3973	605343	NP_005851	NM_005860	ENSP00000166139	known	1	0	0	Eukaryotes	19	8	Regulation of intracellular processes and metabolism,Signal transduction	81	chr19	676424	681705	CGC	leukemia
56884	FSTL5	follistatin-like 5	4q32.3	10998	21386	-	NP_001121899;NP_001121900;NP_064501	NM_001128427;NM_001128428;NM_020116	ENSP00000368462;ENSP00000305334	candidate	0	0	0	Eukaryotes	1	0	-1	-1	chr4	162306902	163032548	WES	chronic lymphocytic leukemia
10841	FTCD	formiminotransferase cyclodeaminase	21q22.3	08430	3974	606806	NP_006648;NP_996848	NM_006657;NM_206965	ENSP00000291670;ENSP00000380854	candidate	0	0	0	Last Universal Common Ancestor	0	1	Cellular metabolism	30	chr21	47556904	47575437	WES	lymphoma
8880	FUBP1	far upstream element (FUSE) binding protein 1	1p31.1	10349	4004	603444	NP_003893	NM_003902	ENSP00000359804	known	0	1	0	Eukaryotes	52	6	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	102	chr1	78414840	78444688	CGC,WES	oligodendroglioma,chronic lymphocytic leukemia
197258	FUK	fucokinase	16q22.1	16365	29500	608675	NP_659496	NM_145059	ENSP00000288078	candidate	0	0	0	Last Universal Common Ancestor	1	0	Cellular metabolism	-1	chr16	70497094	70513580	WES	pancreas
2521	FUS	fused in sarcoma	16p11.2	00660	4010	137070	NP_004951;NP_001164105;NP_001164408	NM_004960;NM_001170634;NR_028388;NM_001170937;NM_001010850	-	known	1	0	0	Eukaryotes	99	1	DNA/RNA metabolism and transcription,Regulation of transcription	109	chr16	31193832	31202432	CGC	histiocytoma,leukemia,sarcoma
10690	FUT9	fucosyltransferase 9 (alpha (1,3) fucosyltransferase)	6q16	06036	4020	606865	NP_006572	NM_006581	-	candidate	0	0	0	Last Universal Common Ancestor	1	1	Cellular metabolism,Cellular processes	41	chr6	96651032	96652108	WGS	chronic lymphocytic leukemia
7976	FZD3	frizzled family receptor 3	8p21	05849	4041	606143	NP_665873;NP_059108	NM_145866;NM_017412	ENSP00000240093	candidate	0	0	0	Eukaryotes	14	2	Development,Signal transduction	44	chr8	28360531	28420525	WES	colorectal (hypermutated)
10146	G3BP1	GTPase activating protein (SH3 domain) binding protein 1	5q33.1	06569	30292	608431	NP_938405;NP_005745	NM_198395;NM_005754	ENSP00000348578	candidate	0	0	1	Eukaryotes	53	7	Signal transduction	106	chr5	151166182	151183649	WES	melanoma
2549	GAB1	GRB2-associated binding protein 1	4q31.21	05116	4066	604439	NP_997006;NP_002030	NM_207123;NM_002039	ENSP00000262995	candidate	0	0	0	Last Universal Common Ancestor	17	0	Cell motility and interactions,Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction	35	chr4	144258342	144390339	WES	breast
2550	GABBR1	gamma-aminobutyric acid (GABA) B receptor, 1	6p21.31	04644	4070	603540	NP_068704;NP_001461;NP_068703	NM_021905;NM_021904;NM_001470;NM_021903	ENSP00000366233;ENSP00000366211;ENSP00000366215	candidate	0	0	0	Last Universal Common Ancestor	19	2	Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction	74	chr6	29571323	29600162	WGS	liver
2554	GABRA1	gamma-aminobutyric acid (GABA) A receptor, alpha 1	5q34	00662	4075	137160	NP_001121118;NP_001121115;NP_001121116;NP_001121120;NP_000797;NP_001121117;NP_001121119	NM_001127646;NM_001127643;NM_001127644;NM_001127648;NM_000806;NM_001127645;NM_001127647	ENSP00000393097;ENSP00000415441	candidate	0	0	2	Metazoans	0	1	Cellular processes,Signal transduction	20	chr5	161277817	161324425	WES	lymphoma
2562	GABRB3	gamma-aminobutyric acid (GABA) A receptor, beta 3	15q11.2-q12	08844	4083	137192	NP_001178250;NP_001178249;NP_068712;NP_000805	NM_001191321;NM_001191320;NM_021912;NM_000814	ENSP00000308725;ENSP00000442408	candidate	0	0	2	Eukaryotes	0	1	Cellular processes,Multicellular activities,Signal transduction	29	chr15	26792943	27018109	WGS	liver
2565	GABRG1	gamma-aminobutyric acid (GABA) A receptor, gamma 1	4p12	15923	4086	137166	NP_775807	NM_173536	ENSP00000295452	candidate	0	0	0	Metazoans	1	0	Cellular processes,Multicellular activities,Signal transduction	-1	chr4	46043008	46125930	WGS	medulloblastoma
2588	GALNS	galactosamine (N-acetyl)-6-sulfate sulfatase	16q24.3	08357	4122	612222	NP_000503	NM_000512	ENSP00000268695	candidate	0	0	0	Last Universal Common Ancestor	0	0	Cellular metabolism	61	chr16	88880850	88923285	WES	colorectal
114805	GALNT13	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13 (GalNAc-T13)	2q24.1	16325	23242	608369	NP_443149	NM_052917	ENSP00000376570	candidate	0	0	1	Eukaryotes	4	0	-1	-1	chr2	154801011	155307060	WES	pancreas
11227	GALNT5	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)	2q24.1	09970	4127	-	NP_055383	NM_014568	-	candidate	0	0	0	Eukaryotes	0	1	Cellular metabolism	-1	chr2	158114595	158167857	WES	breast
442117	GALNTL6	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 6	4q34.1	-	33844	-	NP_001030017	NM_001034845	-	candidate	0	0	0	Last Universal Common Ancestor	0	0	-1	-1	chr4	172735732	173961248	WES	breast
2617	GARS	glycyl-tRNA synthetase	7p15	02617	4162	600287	NP_002038	NM_002047	ENSP00000373918	candidate	0	0	0	Last Universal Common Ancestor	30	2	Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of transcription	98	chr7	30634538	30673473	WGS	lung
8522	GAS7	growth arrest-specific 7	17p13.1	16011	4169	603127	NP_001124303;NP_958836;NP_958839;NP_003635	NM_001130831;NM_201432;NM_201433;NM_003644	ENSP00000410108;ENSP00000379421	known	1	0	0	Eukaryotes	36	2	Cell cycle,Development	92	chr17	9820548	10101707	CGC	leukemia
2623	GATA1	GATA binding protein 1 (globin transcription factor 1)	Xp11.23	02372	4170	305371	NP_002040	NM_002049	ENSP00000365858	known	1	0	0	Eukaryotes	52	1	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	13	chrX	48649517	48652568	CGC	leukemia
2624	GATA2	GATA binding protein 2	3q21.3	00673	4171	137295	NP_116027;NP_001139134;NP_001139133	NM_032638;NM_001145662;NM_001145661	ENSP00000345681	known	1	0	0	Eukaryotes	30	1	Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription	82	chr3	128199865	128205874	CGC,WES	leukemia
2625	GATA3	GATA binding protein 3	10p15	00572	4172	131320	NP_001002295;NP_002042	NM_001002295;NM_002051	ENSP00000368632;ENSP00000341619	known	0	1	0	Eukaryotes	19	3	Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription	76	chr10	8097619	8115983	CGC,WES	breast
2627	GATA6	GATA binding protein 6	18q11.1-q11.2	09043	4174	601656	NP_005248	NM_005257	ENSP00000269216	known	0	0	0	Eukaryotes	11	16	Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription	30	chr18	19751106	19780783	CGC,Amplified	
145781	GCOM1	GRINL1A complex locus 1	15q21.3	08091	26424	614071	NP_001018101;NP_001018100	NM_001018094;NM_001018099;NM_001018096;NM_001018097;NM_001018098;NM_001018093;NM_001018091;NM_001018092;NM_001018090;NM_001018095	-	candidate	0	0	0	Last Universal Common Ancestor	0	0	-1	36	chr15	57884233	58006874	WGS	glioblastoma
339970	GCOM2	GRINL1B complex locus 2, pseudogene	4q12	-	15712	608311	-	-	-	candidate	0	0	-1	Last Universal Common Ancestor	1	0	-1	-1	-	0	0	WGS	acute myeloid leukemia
9615	GDA	guanine deaminase	9q21.13	08849	4212	139260	NP_001229435;NP_001229436;NP_004284;NP_001229434	NM_001242506;NM_001242507;NM_004293;NM_001242505	ENSP00000436619;ENSP00000351170	candidate	0	0	0	Last Universal Common Ancestor	12	3	Development	-1	chr9	74764476	74865717	WGS	chronic lymphocytic leukemia
348654	GEN1	Gen endonuclease homolog 1 (Drosophila)	2p24.2	08813	26881	612449	NP_001123481;NP_872431	NM_001130009;NM_182625	ENSP00000370653;ENSP00000318977	candidate	0	0	0	Last Universal Common Ancestor	1	2	DNA/RNA metabolism and transcription	-1	chr2	17941211	17963203	WES	breast
26088	GGA1	golgi-associated, gamma adaptin ear containing, ARF binding protein 1	22q13.31	12078	17842	606004	NP_001166159;NP_001166158;NP_037497;NP_001001560;NP_001001561	NM_001172688;NM_001172687;NM_013365;NM_001001560;NM_001001561	ENSP00000321288;ENSP00000414387;ENSP00000385287;ENSP00000341344	candidate	0	0	0	Eukaryotes	39	0	Cellular processes	109	chr22	38010199	38028715	WES	breast
2693	GHSR	growth hormone secretagogue receptor	3q26.31	03541	4267	601898	NP_004113;NP_940799	NM_004122;NM_198407	ENSP00000395344	candidate	0	0	0	Metazoans	2	1	Cell cycle,Cell response to stimuli,Cellular metabolism,Cellular processes,Development,Immune system response,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction	5	chr3	172162954	172166203	WGS	prostate
2694	GIF	gastric intrinsic factor (vitamin B synthesis)	11q13	02024	4268	609342	NP_005133	NM_005142	ENSP00000257248	candidate	0	0	0	Eukaryotes	4	0	Cellular processes	26	chr11	59596960	59612926	WGS	liver
26058	GIGYF2	GRB10 interacting GYF protein 2	2q37.1	11639	11960	612003	NP_056390;NP_001096617;NP_001096618;NP_001096616	NM_015575;NM_001103147;NM_001103148;NM_001103146	ENSP00000362667	candidate	0	0	0	Eukaryotes	41	1	-1	102	chr2	233599908	233721567	WES	pancreas
219770	GJD4	gap junction protein, delta 4, 40.1kDa	10p11.21	13103	23296	611922	NP_699199	NM_153368	ENSP00000315070	candidate	0	0	0	Vertebrates	1	0	-1	-1	chr10	35894496	35897551	WES	colorectal
56287	GKN1	gastrokine 1	2p13.3	16217	23217	606402	NP_062563	NM_019617	ENSP00000367172	candidate	0	0	0	Vertebrates	1	1	Cell cycle,Regulation of intracellular processes and metabolism	10	chr2	69201768	69207952	WES	acute myeloid leukemia
2734	GLG1	golgi glycoprotein 1	16q22.3	02855	4316	600753	NP_001139139;NP_001139138;NP_036333	NR_027264;NR_027265;NM_001145667;NM_001145666;NM_012201	-	candidate	0	0	0	Last Universal Common Ancestor	8	3	-1	109	chr16	74485957	74640992	WGS	lymphoma
2735	GLI1	GLI family zinc finger 1	12q13.2-q13.3	01311	4317	165220	NP_005260;NP_001161081;NP_001153517	NM_005269;NM_001167609;NM_001160045	ENSP00000437607;ENSP00000441006;ENSP00000228682	candidate	0	0	0	Last Universal Common Ancestor	17	5	Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	24	chr12	57857475	57865841	WES,WGS	breast,melanoma
2737	GLI3	GLI family zinc finger 3	7p13	01313	4319	165240	NP_000159	NM_000168	ENSP00000379258	candidate	0	0	0	Last Universal Common Ancestor	3	0	Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	56	chr7	42003931	42262852	HTMS,WES	breast,lung,ovarian,pancreas,prostate,colorectal
152007	GLIPR2	GLI pathogenesis-related 2	9p13.3	06187	18007	607141	NP_071738	NM_022343	ENSP00000367196	candidate	0	0	0	Last Universal Common Ancestor	4	1	-1	-1	chr9	36147782	36162516	WES	melanoma
29998	GLTSCR1	glioma tumor suppressor candidate region gene 1	19q13.3	09296	4332	605690	NP_056526	NM_015711	ENSP00000379946	candidate	0	0	0	Eukaryotes	17	0	-1	37	chr19	48176832	48205669	WES	pancreas
2765	GML	glycosylphosphatidylinositol anchored molecule like protein	8q24.3	03844	4375	602370	NP_002057	NM_002066	ENSP00000220940	candidate	0	0	0	Mammals	0	0	Cell cycle,Regulation of intracellular processes and metabolism,Signal transduction	55	chr8	143921854	143928103	WES	glioblastoma
8833	GMPS	guanine monphosphate synthetase	3q24	10927	4378	600358	NP_003866	NM_003875	ENSP00000438199	known	1	0	0	Last Universal Common Ancestor	25	1	Cellular metabolism,DNA/RNA metabolism and transcription	88	chr3	155611307	155655478	CGC	leukemia
2767	GNA11	guanine nucleotide binding protein (G protein), alpha 11 (Gq class)	19p13.3	00759	4379	139313	NP_002058	NM_002067	-	known	1	0	3	Eukaryotes	23	0	Cellular metabolism,Cellular processes,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction	96	chr19	3094650	3121174	CGC	melanoma
10672	GNA13	guanine nucleotide binding protein (G protein), alpha 13	17q24.3	05100	4381	604406	NP_006563	NM_006572	-	candidate	0	0	0	Eukaryotes	2	6	Cell motility and interactions,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction	12	chr17	63010378	63052711	WES,WGS	lymphoma,non-hodgkin lymphoma
2769	GNA15	guanine nucleotide binding protein (G protein), alpha 15 (Gq class)	19p13.3	00760	4383	139314	NP_002059	NM_002068	ENSP00000262958	candidate	0	0	0	Eukaryotes	0	0	Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction	45	chr19	3136449	3163014	WES	melanoma
2776	GNAQ	guanine nucleotide binding protein (G protein), q polypeptide	9q21	02998	4390	600998	NP_002063	NM_002072	-	known	1	0	3	Eukaryotes	70	4	Cell cycle,Cellular metabolism,Cellular processes,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction	104	chr9	80336242	80646151	CGC	melanoma
2778	GNAS	GNAS complex locus	20q13.3	00761	4392	139320	NP_536351;NP_001070957;NP_057676;NP_536350;NP_001070958;NP_000507;NP_001070956	NM_080426;NM_001077489;NM_016592;NM_080425;NM_001077490;NM_000516;NR_003259;NM_001077488	ENSP00000360126;ENSP00000346328;ENSP00000265620;ENSP00000360115;ENSP00000360141;ENSP00000360136	known	1	0	0	Last Universal Common Ancestor	55	1	Cell response to stimuli,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction	109	chr20	57428321	57485881	CGC,HTMS,WES	pituitary,breast,lung,ovarian,pancreas,prostate,cholangiocarcinoma,colorectal
2779	GNAT1	guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1	3p21	08850	4393	139330	NP_000163;NP_653082	NM_000172;NM_144499	-	candidate	0	0	2	Eukaryotes	4	0	Cell response to stimuli,Signal transduction	9	chr3	50229159	50232385	WES	chronic lymphocytic leukemia
59345	GNB4	guanine nucleotide binding protein (G protein), beta polypeptide 4	3q26.33	09973	20731	610863	NP_067642	NM_021629	-	candidate	0	0	3	Last Universal Common Ancestor	24	7	Signal transduction	-1	chr3	179119004	179143988	WGS	melanoma
2803	GOLGA4	golgin A4	3p22-p21.3	03941	4427	602509	NP_001166184;NP_002069	NM_001172713;NM_002078	ENSP00000349305;ENSP00000354486	candidate	0	0	0	Last Universal Common Ancestor	7	2	Cellular processes	86	chr3	37285042	37396678	WGS	breast
9950	GOLGA5	golgin A5	14q	06079	4428	606918	NP_005104	NM_005113	ENSP00000163416	known	1	0	0	Eukaryotes	5	3	Cellular metabolism,Cellular processes	93	chr14	93263783	93305788	CGC	thyroid
727832	GOLGA6L6	golgin A6 family-like 6	15q11.2	-	37225	-	NP_001138476	NM_001145004	-	candidate	0	0	3	Last Universal Common Ancestor	0	0	-1	-1	chr15	20739500	20747023	WGS	melanoma
401647	GOLGA7B	golgin A7 family, member B	10q24.2	16579	31668	614189	NP_001010917	NM_001010917;XR_110442;XR_111108	-	candidate	0	0	0	Eukaryotes	0	0	-1	-1	chr10	99619215	99625454	WGS	glioblastoma
57120	GOPC	golgi-associated PDZ and coiled-coil motif containing	6q21	06024	17643	606845	NP_065132;NP_001017408	NM_020399;NM_001017408	ENSP00000052569;ENSP00000357484	known	1	0	0	Eukaryotes	34	3	Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism	-1	chr6	117884420	117923451	CGC	glioblastoma
57678	GPAM	glycerol-3-phosphate acyltransferase, mitochondrial	10q25.2	03865	24865	602395	NP_065969;NP_001231878	NM_020918;NM_001244949	ENSP00000265276;ENSP00000409242	candidate	0	0	0	Last Universal Common Ancestor	2	9	Cellular metabolism	-1	chr10	113913311	113941542	WGS	medulloblastoma
2719	GPC3	glypican 3	Xq26.1	02074	4451	300037	NP_004475;NP_001158089;NP_001158090;NP_001158091	NM_004484;NM_001164617;NM_001164618;NM_001164619	ENSP00000377836;ENSP00000359854	known	0	1	0	Metazoans	6	0	-1	53	chrX	132670155	133119476	CGC	
2262	GPC5	glypican 5	13q32	03902	4453	602446	NP_004457	NM_004466	ENSP00000366267	known	0	0	0	Metazoans	1	0	-1	19	chr13	92051301	92797241	CGC,Amplified	
10082	GPC6	glypican 6	13q32	05099	4454	604404	NP_005699	NM_005708	-	candidate	0	0	0	Metazoans	3	0	-1	-1	chr13	93879710	95055468	WES,WGS	colorectal (non-hypermutated),prostate
56261	GPCPD1	glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)	20p12.3	10025	26957	614124	NP_062539	NM_019593	ENSP00000368305	candidate	0	0	1	Eukaryotes	45	0	Cellular metabolism	-1	chr20	5528310	5585058	WGS	chronic lymphocytic leukemia
122876	GPHB5	glycoprotein hormone beta 5	14q23.2	17053	18055	609652	NP_660154	NM_145171	-	candidate	0	0	0	Metazoans	1	2	-1	-1	chr14	63779645	63784563	WGS	glioblastoma
10243	GPHN	gephyrin	14q23.3	04893	15465	603930	NP_065857;NP_001019389	NM_020806;NM_001024218	ENSP00000312771;ENSP00000417901	known	1	0	0	Last Universal Common Ancestor	7	0	Cellular metabolism	57	chr14	66975246	67647651	CGC	leukemia
139378	GPR112	G protein-coupled receptor 112	Xq26.3	06578	18992	-	NP_722576	NM_153834	ENSP00000377699	candidate	0	0	0	Last Universal Common Ancestor	0	1	Signal transduction	-1	chrX	135390937	135496485	WES,WGS	colorectal,lung
84435	GPR123	G protein-coupled receptor 123	10q26	17058	13838	612302	NP_001077378	NM_032422;NM_001083909	ENSP00000376384	candidate	0	0	0	Eukaryotes	0	3	Signal transduction	-1	chr10	134910478	134943012	WGS	acute myeloid leukemia
283383	GPR133	G protein-coupled receptor 133	12q24.33	17061	19893	613639	NP_942122	NM_198827	ENSP00000261654	candidate	0	0	0	Eukaryotes	0	0	Signal transduction	-1	chr12	131439011	131623805	WES	pancreas
57512	GPR158	G protein-coupled receptor 158	10p12.1	13601	23689	-	NP_065803	NM_020752	ENSP00000365529	candidate	0	0	0	Metazoans	3	0	Signal transduction	-1	chr10	25464350	25888200	WES	colorectal
84636	GPR174	G protein-coupled receptor 174	Xq21.1	06512	30245	-	NP_115942	NM_032553	ENSP00000276077	candidate	0	0	0	Vertebrates	0	0	Signal transduction	-1	chrX	78426505	78427503	WES	head and neck squamous cell carcinoma
1880	GPR183	G protein-coupled receptor 183	13q32.3	12040	3128	605741	NP_004942	NM_004951	ENSP00000365596	candidate	0	0	0	Vertebrates	3	1	Signal transduction	31	chr13	99947317	99948399	WGS	acute myeloid leukemia
2854	GPR32	G protein-coupled receptor 32	19q13.33	04430	4487	603195	NP_001497	NM_001506	ENSP00000270590	candidate	0	0	1	Mammals	0	0	Signal transduction	27	chr19	51273858	51274925	WES	breast
53831	GPR84	G protein-coupled receptor 84	12q13.13	16213	4535	606383	NP_065103	NM_020370	ENSP00000267015	candidate	0	0	0	Metazoans	6	0	Signal transduction	-1	chr12	54756448	54757635	HTMS	breast,lung,ovarian,pancreas,prostate
9721	GPRIN2	G protein regulated inducer of neurite outgrowth 2	10q11.22	13804	23730	611240	NP_055511	NM_014696	-	candidate	0	0	0	Metazoans	16	1	-1	52	chr10	46998881	47000254	WGS	lymphoma
2874	GPS2	G protein pathway suppressor 2	17p13	11878	4550	601935	NP_004480	NM_004489	ENSP00000370104	candidate	0	0	1	Eukaryotes	35	0	Regulation of intracellular processes and metabolism,Signal transduction	35	chr17	7216078	7218371	WES,WGS	breast,medulloblastoma,lymphoma
2875	GPT	glutamic-pyruvate transaminase (alanine aminotransferase)	8q24.3	00689	4552	138200	NP_005300	NM_005309	ENSP00000378408	candidate	0	0	0	Last Universal Common Ancestor	1	0	Cellular metabolism	13	chr8	145729688	145732380	WGS	lymphoma
2887	GRB10	growth factor receptor-bound protein 10	7p12.2	03312	4564	601523	NP_001001550;NP_001001549;NP_005302;NP_001001555	NM_001001550;NM_001001549;NM_005311;NM_001001555	ENSP00000381790;ENSP00000338543;ENSP00000381793	candidate	0	0	0	Eukaryotes	42	2	Signal transduction	98	chr7	50660652	50800019	HTMS	breast,lung,ovarian,pancreas,prostate
2885	GRB2	growth factor receptor-bound protein 2	17q24-q25	00150	4566	108355	NP_002077;NP_987102	NM_002086;NM_203506	ENSP00000339007;ENSP00000317360	candidate	0	0	0	Eukaryotes	1008	11	Signal transduction	96	chr17	73316452	73389709	WES	lymphoma
2886	GRB7	growth factor receptor-bound protein 7	17q12	03311	4567	601522	NP_001229372;NP_001229371;NP_001025173;NP_005301	NM_001242443;NM_001242442;NM_001030002;NM_005310	ENSP00000377761;ENSP00000403459;ENSP00000377759;ENSP00000310771	known	0	0	0	Eukaryotes	61	2	Signal transduction	53	chr17	37898501	37903147	CGC,Amplified	
80000	GREB1L	growth regulation by estrogen in breast cancer-like	18q11.2	11161	31042	-	NP_001136438	NM_024935;NM_001142966	ENSP00000412060	candidate	0	0	0	Metazoans	51	1	-1	27	chr18	18963480	19102779	WGS	breast
79977	GRHL2	grainyhead-like 2 (Drosophila)	8q22.3	10545	2799	608576	NP_079191	NM_024915	ENSP00000251808	candidate	0	0	0	Opisthokonts	7	1	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	59	chr8	102555470	102678928	WGS	lymphoma
2890	GRIA1	glutamate receptor, ionotropic, AMPA 1	5q33|5q31.1	00695	4571	138248	NP_000818;NP_001107655	NM_000827;NM_001114183	ENSP00000285900;ENSP00000428994	candidate	0	0	0	Metazoans	34	2	Cellular processes,Multicellular activities,Signal transduction	38	chr5	152870449	153190782	WGS	melanoma
2892	GRIA3	glutamate receptor, ionotrophic, AMPA 3	Xq25	02378	4573	305915	NP_015564;NP_000819	NM_007325;NM_000828;NM_181894	ENSP00000264357;ENSP00000360311;ENSP00000360302	candidate	0	0	0	Metazoans	5	0	Cellular processes,Signal transduction	22	chrX	122318388	122616892	WES	pancreas
2894	GRID1	glutamate receptor, ionotropic, delta 1	10q22	17078	4575	610659	NP_060021	NM_017551	ENSP00000330148	candidate	0	0	0	Eukaryotes	0	0	Cellular processes	-1	chr10	87362033	88126149	WES,WGS	colorectal,glioblastoma
2899	GRIK3	glutamate receptor, ionotropic, kainate 3	1p34-p33	00691	4581	138243	NP_000822	NM_000831	ENSP00000362183	candidate	0	0	1	Eukaryotes	0	0	Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction	0	chr1	37267455	37499709	WES	lung
2903	GRIN2A	glutamate receptor, ionotropic, N-methyl D-aspartate 2A	16p13.2	00698	4585	138253	NP_000824;NP_001127880;NP_001127879	NM_000833;NM_001134408;NM_001134407	ENSP00000385872	candidate	0	0	0	Metazoans	29	1	Cellular processes,Development,Multicellular activities,Signal transduction	47	chr16	9857009	10274268	WES	melanoma
2906	GRIN2D	glutamate receptor, ionotropic, N-methyl D-aspartate 2D	19q13.1-qter	04095	4588	602717	NP_000827	NM_000836	ENSP00000263269	candidate	0	0	0	Metazoans	2	1	Cellular processes,Signal transduction	9	chr19	48901650	48947191	WES	breast
116444	GRIN3B	glutamate receptor, ionotropic, N-methyl-D-aspartate 3B	19p13.3	-	16768	606651	XP_003403748;NP_619635	XM_003403700;NM_138690	ENSP00000234389	candidate	0	0	0	Metazoans	3	0	Cellular processes,Regulation of intracellular processes and metabolism	-1	chr19	996384	1009598	WGS	lymphoma
2911	GRM1	glutamate receptor, metabotropic 1	6q24	05129	4593	604473	NP_001107801;NP_000829	NM_001114329;NM_000838	ENSP00000354896;ENSP00000376119	candidate	0	0	0	Metazoans	16	3	Multicellular activities,Signal transduction	50	chr6	146350654	146755929	HTMS,WES	breast,lung,ovarian,pancreas,prostate,colorectal
2913	GRM3	glutamate receptor, metabotropic 3	7q21.1-q21.2	03070	4595	601115	NP_000831	NM_000840	ENSP00000355316	candidate	0	0	1	Metazoans	7	1	Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction	40	chr7	86394462	86493668	HTMS,WES,WGS	breast,lung,ovarian,pancreas,prostate,glioblastoma,chronic lymphocytic leukemia
2915	GRM5	glutamate receptor, metabotropic 5	11q14.3	-	4597	604102	NP_000833;NP_001137303	NM_000842;NM_001143831	ENSP00000405690;ENSP00000402912	candidate	0	0	0	Metazoans	17	1	Multicellular activities,Signal transduction	29	chr11	88241763	88781040	WGS	prostate
2918	GRM8	glutamate receptor, metabotropic 8	7q31.3-q32.1	03071	4600	601116	NP_000836;NP_001120795	NM_000845;NM_001127323;NR_028041	ENSP00000409790;ENSP00000351142	candidate	0	0	2	Metazoans	4	1	Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	32	chr7	126079176	126883258	HTMS,WES	breast,lung,ovarian,pancreas,prostate,head and neck squamous cell carcinoma
643226	GRXCR2	glutaredoxin, cysteine rich 2	5q32	-	33862	-	NP_001073985	NM_001080516	ENSP00000367214	candidate	0	0	0	Eukaryotes	0	0	-1	-1	chr5	145239299	145252531	WGS	melanoma
2932	GSK3B	glycogen synthase kinase 3 beta	3q13.3	05418	4617	605004	NP_002084;NP_001139628	NM_002093;NM_001146156	ENSP00000264235	candidate	0	0	1	Last Universal Common Ancestor	327	2	Cell cycle,Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction	92	chr3	119545638	119812281	HTMS	breast,lung,ovarian,pancreas,prostate
2934	GSN	gelsolin	9q33	00674	4620	137350	NP_001121134;NP_001121138;NP_000168;NP_001121136;NP_001121135;NP_001121137;NP_001121139;NP_937895	NM_001127662;NM_001127666;NM_000177;NM_001127664;NM_001127663;NM_001127665;NM_001127667;NM_198252	ENSP00000362924;ENSP00000362914;ENSP00000416586;ENSP00000411293;ENSP00000377882;ENSP00000340888	candidate	0	0	0	Eukaryotes	56	4	Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism	104	chr9	124062140	124094878	WES	breast
79807	GSTCD	glutathione S-transferase, C-terminal domain containing	4q24	07823	25806	-	NP_079027;NP_001026890	NM_024751;NM_001031720	ENSP00000378216;ENSP00000378218	candidate	0	0	0	Last Universal Common Ancestor	1	2	-1	41	chr4	106638771	106766731	WGS	breast
9330	GTF3C3	general transcription factor IIIC, polypeptide 3, 102kDa	2q33.1	11997	4666	604888	NP_036218;NP_001193703	NM_012086;NM_001206774	ENSP00000386465;ENSP00000263956	candidate	0	0	0	Eukaryotes	18	3	Cellular metabolism,DNA/RNA metabolism and transcription	62	chr2	197629290	197664335	WGS	breast
54676	GTPBP2	GTP binding protein 2	6p21	08465	4670	607434	NP_061969	NM_019096	ENSP00000303997	candidate	0	0	0	Last Universal Common Ancestor	169	0	Signal transduction	55	chr6	43589354	43596899	WGS	liver
2977	GUCY1A2	guanylate cyclase 1, soluble, alpha 2	11q21-q22	03146	4684	601244	NP_001243353;NP_000846	NM_001256424;NM_000855	-	candidate	0	0	0	Last Universal Common Ancestor	10	1	Cellular metabolism,DNA/RNA metabolism and transcription,Signal transduction	23	chr11	106558278	106888781	WES	colorectal,pancreas
2987	GUK1	guanylate kinase 1	1q32-q41	00755	4693	139270	NP_001229769;NP_001152863;NP_001229768;NP_000849;NP_001152862	NM_001242840;NM_001159391;NM_001242839;NM_000858;NM_001159390	ENSP00000317659;ENSP00000375738;ENSP00000355677;ENSP00000355689	candidate	0	0	0	Last Universal Common Ancestor	3	3	Cellular metabolism,DNA/RNA metabolism and transcription	107	chr1	228328004	228336550	WGS	breast
283464	GXYLT1	glucoside xylosyltransferase 1	12q12	-	27482	613321	NP_001093120;NP_775872	NM_001099650;NM_173601	ENSP00000381666	candidate	0	0	4	Last Universal Common Ancestor	5	5	Cellular metabolism	-1	chr12	42481591	42538448	WGS	liver,lymphoma
132243	H1FOO	H1 histone family, member O, oocyte-specific	3q22.1	13621	18463	-	NP_722575	NM_153833	ENSP00000319799	candidate	0	0	1	Eukaryotes	0	0	Cell cycle,DNA/RNA metabolism and transcription	-1	chr3	129262062	129270180	WES	lymphoma
3020	H3F3A	H3 histone, family 3A	1q42.12	03082	4764	601128	NP_002098	NM_002107	ENSP00000355780	known	1	0	36	Last Universal Common Ancestor	71	1	-1	36	chr2	175584636	175585043	CGC,WES	glioma,glioblastoma
440093	H3F3C	H3 histone, family 3C	12p11.21	18443	33164	-	NP_001013721	NM_001013699	ENSP00000339835	candidate	0	0	33	Last Universal Common Ancestor	3	2	DNA/RNA metabolism and transcription	-1	chr12	31944696	31945100	WES	head and neck squamous cell carcinoma
9563	H6PD	hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)	1p36	00681	4795	138090	NP_004276	NM_004285	ENSP00000366620	candidate	0	0	0	Last Universal Common Ancestor	1	4	Cellular metabolism,DNA/RNA metabolism and transcription	52	chr1	9304994	9324925	WGS	prostate
1404	HAPLN1	hyaluronan and proteoglycan link protein 1	5q14.3	00275	2380	115435	NP_001875	NM_001884	ENSP00000274341	candidate	0	0	0	Eukaryotes	9	2	-1	8	chr5	82937318	82969342	WES	colorectal
3035	HARS	histidyl-tRNA synthetase	5q31.3	00827	4816	142810	NP_002100	NM_002109	ENSP00000411511;ENSP00000387893;ENSP00000304668	candidate	0	0	0	Last Universal Common Ancestor	17	6	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of transcription	91	chr5	140053845	140070889	WGS	lymphoma
3036	HAS1	hyaluronan synthase 1	19q13.4	03271	4818	601463	NP_001514	NM_001523	ENSP00000222115	candidate	0	0	0	Last Universal Common Ancestor	6	0	Cellular metabolism	13	chr19	52216683	52223154	WGS	lymphoma
79441	HAUS3	HAUS augmin-like complex, subunit 3	4p16.3	10784	28719	613430	NP_078787	NM_024511	ENSP00000243706	candidate	0	0	0	Eukaryotes	6	7	-1	29	chr4	2233657	2242673	WGS	breast
348980	HCN1	hyperpolarization activated cyclic nucleotide-gated potassium channel 1	5p12	09099	4845	602780	NP_066550	NM_021072	-	candidate	0	0	0	Last Universal Common Ancestor	4	0	Cellular processes	-1	chr5	45262026	45696195	WES	lung
10021	HCN4	hyperpolarization activated cyclic nucleotide-gated potassium channel 4	15q24.1	09240	16882	605206	NP_005468	NM_005477	ENSP00000261917	candidate	0	0	0	Last Universal Common Ancestor	2	6	Cellular processes,Development,Multicellular activities	18	chr15	73614825	73660611	WGS	liver
3066	HDAC2	histone deacetylase 2	6q21	05521	4853	605164	NP_001518	NM_001527;NR_033441	ENSP00000381331	candidate	0	0	1	Last Universal Common Ancestor	73	3	Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	93	chr6	114262871	114292072	WGS	melanoma
9759	HDAC4	histone deacetylase 4	2q37.3	05610	14063	605314	NP_006028	NM_006037	ENSP00000264606	candidate	0	0	0	Last Universal Common Ancestor	25	10	Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Immune system response,Regulation of intracellular processes and metabolism,Regulation of transcription	54	chr2	239975155	240158364	WES	breast
9734	HDAC9	histone deacetylase 9	7p21.1	05944	14065	606543	NP_478056;NP_001191074;NP_001191075;NP_001191077;NP_848512;NP_055522;NP_848510;NP_001191076;NP_001191073	NM_058177;NM_058176;NM_001204145;NM_001204146;NM_001204148;NM_178425;NM_014707;NM_178423;NM_001204147;NM_001204144	ENSP00000384017;ENSP00000384382;ENSP00000410337;ENSP00000384657	candidate	0	0	0	Last Universal Common Ancestor	87	0	Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Immune system response,Regulation of intracellular processes and metabolism,Regulation of transcription	54	chr7	18624897	19015577	WGS	prostate
3069	HDLBP	high density lipoprotein binding protein	2q37.3	00813	4857	142695	NP_005327;NP_001230829;NP_976221	NM_005336;NM_001243900;NM_203346	ENSP00000375836	candidate	0	0	0	Eukaryotes	43	4	Cellular metabolism,Cellular processes	104	chr2	242169019	242206284	WES	breast
399671	HEATR4	HEAT repeat containing 4	14q24.3	14657	16761	-	NP_976054;NP_001207413	NM_203309;NM_001220484	ENSP00000450444;ENSP00000335447	candidate	0	0	0	Eukaryotes	1	0	-1	-1	chr14	73945314	73989856	WGS	glioblastoma
92797	HELB	helicase (DNA) B	12q14.3	09979	17196	-	NP_387467	NM_033647	ENSP00000443287	candidate	0	0	0	Last Universal Common Ancestor	5	0	Cellular metabolism,DNA/RNA metabolism and transcription	-1	chr12	66696384	66731879	WGS	melanoma
8924	HERC2	hect domain and RLD 2	15q13	06905	4868	605837	NP_004658	NM_004667	ENSP00000261609	candidate	0	0	0	Eukaryotes	60	3	Cellular metabolism,Cellular processes	69	chr15	28356912	28566579	WGS	lung
9709	HERPUD1	homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1	16q13	07456	13744	608070	NP_001010990;NP_055500;NP_001010989	NM_001010990;NM_014685;NM_001010989	ENSP00000300302;ENSP00000409555	known	1	0	0	Eukaryotes	36	4	Cell response to stimuli,Cellular metabolism,Cellular processes	108	chr16	56966157	56977199	CGC	prostate
23462	HEY1	hairy/enhancer-of-split related with YRPW motif 1	8q21	04260	4880	602953	NP_036390;NP_001035798	NM_012258;NM_001040708	ENSP00000338272;ENSP00000346761	known	1	0	0	Opisthokonts	8	2	Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	95	chr8	80677426	80679898	CGC	sarcoma
25988	HINFP	histone H4 transcription factor	11q23.3	07387	17850	607099	NP_945322;NP_056332;NP_001230188	NM_198971;NM_015517;NM_001243259	-	candidate	0	0	0	Metazoans	1	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	10	chr11	118997655	119005205	WES	pancreas
3092	HIP1	huntingtin interacting protein 1	7q11.23	03461	4913	601767	NP_005329;NP_001230127	NM_005338;NM_001243198	ENSP00000410300;ENSP00000336747	known	1	0	0	Eukaryotes	9	0	Cell cycle,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction	53	chr7	75167496	75368238	CGC	leukemia
3009	HIST1H1B	histone cluster 1, H1b	6p22.1	00821	4719	142711	NP_005313	NM_005322	ENSP00000330074	candidate	0	0	3	Eukaryotes	26	3	DNA/RNA metabolism and transcription,Development	7	chr6	27834630	27835307	WES	colorectal
3006	HIST1H1C	histone cluster 1, H1c	6p21.3	07514	4716	142710	NP_005310	NM_005319	ENSP00000339566	candidate	0	0	3	Eukaryotes	15	2	DNA/RNA metabolism and transcription	75	chr6	26056018	26056656	WES	lymphoma,non-hodgkin lymphoma
3008	HIST1H1E	histone cluster 1, H1e	6p21.3	07513	4718	142220	NP_005312	NM_005321	ENSP00000307705	candidate	0	0	3	Eukaryotes	11	1	DNA/RNA metabolism and transcription	2	chr6	26156619	26157275	WES	lymphoma
8332	HIST1H2AL	histone cluster 1, H2al	6p22.1	09103	4730	602793	NP_003502	NM_003511	ENSP00000349873	candidate	0	0	-1	Eukaryotes	14	1	-1	5	-	0	0	WES	lymphoma
8347	HIST1H2BC	histone cluster 1, H2bc	6p22.1	13656	4757	602847	NP_003517	NM_003526	-	candidate	0	0	-1	Eukaryotes	22	2	Cell response to stimuli,DNA/RNA metabolism and transcription	20	-	0	0	WES	breast,lymphoma
8348	HIST1H2BO	histone cluster 1, H2bo	6p22.1	11904	4758	602808	NP_003518	NM_003527	ENSP00000303408	candidate	0	0	26	Eukaryotes	5	2	DNA/RNA metabolism and transcription	1	chr6	27861241	27861618	WES	lymphoma
8358	HIST1H3B	histone cluster 1, H3b	6p22.1	11913	4776	602819	NP_003528	NM_003537	ENSP00000244661	candidate	0	0	-1	Last Universal Common Ancestor	13	3	-1	5	-	0	0	WES	lymphoma
8366	HIST1H4B	histone cluster 1, H4b	6p22.1	11920	4789	602829	NP_003535	NM_003544	ENSP00000366581	candidate	0	0	-1	Last Universal Common Ancestor	0	1	-1	36	-	0	0	WGS	liver
8365	HIST1H4H	histone cluster 1, H4h	6p22.1	11919	4788	602828	NP_003534	NM_003543	ENSP00000366956	candidate	0	0	14	Last Universal Common Ancestor	14	5	-1	36	chr1	149804249	149804557	WES	head and neck squamous cell carcinoma
8294	HIST1H4I	histone cluster 1, H4i	6p21.33	09109	4793	602833	NP_003486	NM_003495	-	known	1	0	14	Last Universal Common Ancestor	37	2	-1	36	chr1	149804249	149804557	CGC	non-hodgkin lymphoma
3101	HK3	hexokinase 3 (white cell)	5q35.2	00806	4925	142570	NP_002106	NM_002115	ENSP00000292432	candidate	0	0	0	Last Universal Common Ancestor	3	0	Cellular metabolism	7	chr5	176308077	176323160	WGS	chronic lymphocytic leukemia
3105	HLA-A	major histocompatibility complex, class I, A	6p21.3	00826	4931	142800	NP_002107;NP_001229687	NM_002116;NM_001242758	ENSP00000366005	candidate	0	0	8	Metazoans	54	8	Immune system response	109	chr6	29910331	29913057	WES,WGS	lung,lymphoma,myeloma
3106	HLA-B	major histocompatibility complex, class I, B	6p21.3	00828	4932	142830	NP_005505	NM_005514	ENSP00000399168	candidate	0	0	6	Vertebrates	307	0	Immune system response	109	chr6	31322263	31324935	WES	lymphoma
3132	HLA-DRB9	major histocompatibility complex, class II, DR beta 9 (pseudogene)	6p21.3	-	4957	-	-	-	-	candidate	0	0	-1	-	0	0	-1	-1	-	0	0	WES	glioblastoma
3131	HLF	hepatic leukemia factor	17q22	00797	4977	142385	NP_002117	NM_002126	ENSP00000226067	known	1	0	0	Metazoans	7	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	69	chr17	53342846	53398237	CGC	leukemia
83872	HMCN1	hemicentin 1	1q25.3-q31.1	06509	19194	608548	NP_114141	NM_031935	ENSP00000271588	candidate	0	0	0	Last Universal Common Ancestor	2	1	Cell response to stimuli,Cellular metabolism,Cellular processes	-1	chr1	185703912	186159007	WES	chronic lymphocytic leukemia,pancreas
3159	HMGA1	high mobility group AT-hook 1	6p21	02829	5010	600701	NP_665910;NP_665908;NP_665912;NP_665906;NP_665909;NP_002122	NM_145903;NM_145904;NM_145901;NM_145905;NM_145899;NM_145902;NM_002131	ENSP00000385693;ENSP00000308227;ENSP00000399888;ENSP00000288245;ENSP00000363230	known	1	0	5	Mammals	58	10	Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Multicellular activities,Other,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	69	chr12	110867767	110868087	CGC	other,thyroid
8091	HMGA2	high mobility group AT-hook 2	12q15	02827	5009	600698	NP_003474;NP_003475	NM_001015886;NM_003483;NM_003484	ENSP00000384026;ENSP00000346658	known	1	0	0	Opisthokonts	20	16	Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	57	chr12	66219051	66357069	CGC	leiomyoma,lipoma,salivary
3146	HMGB1	high mobility group box 1	13q12	01228	4983	163905	NP_002119	NM_002128	-	candidate	0	0	24	Eukaryotes	111	3	Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	109	chr13	31035497	31037817	WES	lymphoma
283651	HMGN2P46	high mobility group nucleosomal binding domain 2 pseudogene 46	15q21.1	16622	26817	611314	-	NM_173609;NR_022014;NM_001005269;NM_001005268;NM_001005267;NM_001005266	-	known	1	0	-1	-	1	0	-1	-1	-	0	0	CGC	prostate
6927	HNF1A	HNF1 homeobox A	12q22-qter|12q24.2	00800	11621	142410	NP_000536	NM_000545	ENSP00000443112	known	0	1	0	Metazoans	12	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	43	chr12	121416572	121438992	CGC,WES	liver,breast
6928	HNF1B	HNF1 homeobox B	17cen-q21.3	08926	11630	189907	NP_000449;NP_001159395	NM_000458;NM_001165923;NM_006481	ENSP00000225893	candidate	0	0	0	Eukaryotes	0	2	Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription	68	chr17	36059082	36104875	WES	lymphoma
3181	HNRNPA2B1	heterogeneous nuclear ribonucleoprotein A2/B1	7p15	02526	5033	600124	NP_112533;NP_002128	NM_031243;NM_002137	ENSP00000346694	known	1	0	0	Last Universal Common Ancestor	105	4	Cellular processes,DNA/RNA metabolism and transcription,Regulation of transcription	108	chr7	26232139	26237486	CGC	prostate
3192	HNRNPU	heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)	1q44	04185	5048	602869	NP_114032;NP_004492	NM_031844;NM_004501	ENSP00000393151	candidate	0	0	0	Eukaryotes	254	5	DNA/RNA metabolism and transcription,Regulation of transcription	109	chr1	245017755	245027609	WGS	lymphoma
84376	HOOK3	hook homolog 3 (Drosophila)	8p11.21	09699	23576	607825	NP_115786	NM_032410	-	known	1	0	0	Eukaryotes	12	1	Cellular processes	-1	chr8	42752275	42873638	CGC	thyroid
3207	HOXA11	homeobox A11	7p15.2	00846	5101	142958	NP_005514	NM_005523	ENSP00000006015	known	1	0	0	Vertebrates	9	3	Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	30	chr7	27222418	27224763	CGC	leukemia
3209	HOXA13	homeobox A13	7p15.2	00847	5102	142959	NP_000513	NM_000522	-	known	1	0	0	Metazoans	7	3	Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription	-1	chr7	27237820	27239696	CGC	leukemia
3200	HOXA3	homeobox A3	7p15.2	00842	5104	142954	NP_109377;NP_705895	NM_030661;NM_153632;NM_153631	ENSP00000379640	candidate	0	0	0	Opisthokonts	0	11	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	9	chr7	27147537	27150259	WES	breast
3205	HOXA9	homeobox A9	7p15.2	00844	5109	142956	NP_689952	NM_152739	ENSP00000343619	known	1	0	0	Metazoans	18	12	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	28	chr7	27203225	27205076	CGC	leukemia
3227	HOXC11	homeobox C11	12q13.3	09275	5123	605559	NP_055027	NM_014212	ENSP00000243082	known	1	0	0	Vertebrates	14	0	Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	56	chr12	54367026	54369194	CGC	leukemia
3229	HOXC13	homeobox C13	12q13.3	00862	5125	142976	NP_059106	NM_017410	ENSP00000243056	known	1	0	0	Metazoans	9	1	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	22	chr12	54332691	54339037	CGC	leukemia
3237	HOXD11	homeobox D11	2q31.1	00869	5134	142986	NP_067015	NM_021192	-	known	1	0	0	Vertebrates	2	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	21	chr2	176972084	176973867	CGC	leukemia
3239	HOXD13	homeobox D13	2q31.1	00872	5136	142989	NP_000514	NM_000523	ENSP00000376322	known	1	0	0	Vertebrates	7	2	Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription	17	chr2	176957619	176959455	CGC	leukemia
3265	HRAS	v-Ha-ras Harvey rat sarcoma viral oncogene homolog	11p15.5	01813	5173	190020	NP_789765;NP_005334;NP_001123914	NM_176795;NM_005343;NM_001130442	ENSP00000407586;ENSP00000309845;ENSP00000388246	known	1	0	2	Last Universal Common Ancestor	111	6	Cell motility and interactions,Development,Signal transduction	76	chr11	532639	534322	CGC,WES	other,sarcoma,bladder,head and neck squamous cell carcinoma,lung,prostate
3270	HRC	histidine rich calcium binding protein	19q13.3	00818	5178	142705	NP_002143	NM_002152	ENSP00000252825	candidate	0	0	0	Opisthokonts	0	1	Multicellular activities	27	chr19	49655259	49658494	WGS	lymphoma,prostate
388697	HRNR	hornerin	1q21.3	17114	20846	-	NP_001009931	NM_001009931	ENSP00000357791	candidate	0	0	3	Last Universal Common Ancestor	14	0	Development	-1	chr1	152185555	152195729	WGS	lymphoma
3320	HSP90AA1	heat shock protein 90kDa alpha (cytosolic), class A member 1	14q32.33	00777	5253	140571	NP_001017963;NP_005339	NM_001017963;NM_005348	ENSP00000335153;ENSP00000216281	known	1	0	6	Last Universal Common Ancestor	412	3	Cell response to stimuli,Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction	108	chr14	102548052	102605741	CGC	non-hodgkin lymphoma
3326	HSP90AB1	heat shock protein 90kDa alpha (cytosolic), class B member 1	6p12	06763	5258	140572	NP_031381	NM_007355	ENSP00000360709	known	1	0	9	Last Universal Common Ancestor	580	1	Cell response to stimuli,Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism	109	chr6	44216367	44221332	CGC	non-hodgkin lymphoma
3306	HSPA2	heat shock 70kDa protein 2	14q24.1	07174	5235	140560	NP_068814	NM_021979	ENSP00000247207	candidate	0	0	12	Last Universal Common Ancestor	8	2	Cell cycle,Cell response to stimuli,Development,Multicellular activities	85	chr14	65007568	65009484	WGS	prostate
3309	HSPA5	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	9q33.3	00682	5238	138120	NP_005338	NM_005347	ENSP00000324173	candidate	0	0	2	Last Universal Common Ancestor	234	3	-1	109	chr9	127998874	128003405	WGS	prostate
3354	HTR1E	5-hydroxytryptamine (serotonin) receptor 1E	6q14-q15	01635	5291	182132	NP_000856	NM_000865	ENSP00000307766	candidate	0	0	0	Metazoans	4	0	Multicellular activities,Signal transduction	16	chr6	87725053	87726147	WES	gastric
54768	HYDIN	HYDIN, axonemal central pair apparatus protein	16q22.2	11042	19368	610812	NP_001185472;NP_060028;NP_001185471;NP_116210	NM_001198543;NM_017558;NM_001198542;NM_032821	ENSP00000444970;ENSP00000437341;ENSP00000377197;ENSP00000314736	candidate	0	0	0	Eukaryotes	1	0	-1	0	chr16	70841486	71220798	WES,WGS	chronic lymphocytic leukemia,lung
7087	ICAM5	intercellular adhesion molecule 5, telencephalin	19p13.2	03509	5348	601852	NP_003250	NM_003259	ENSP00000221980	candidate	0	0	0	Eukaryotes	13	4	-1	32	chr19	10400720	10407289	WES	breast
22858	ICK	intestinal cell (MAK-like) kinase	6p12.1	09996	21219	612325	NP_055735;NP_057597	NM_014920;NM_016513	ENSP00000263043;ENSP00000349458	candidate	0	0	0	Last Universal Common Ancestor	11	4	Cellular metabolism,Cellular processes,Signal transduction	26	chr6	52869950	52906034	WGS	lung
3399	ID3	inhibitor of DNA binding 3, dominant negative helix-loop-helix protein	1p36.13-p36.12	02608	5362	600277	NP_002158	NM_002167	ENSP00000363689	candidate	0	0	0	Vertebrates	42	5	Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription	40	chr1	23885454	23885917	WES,WGS	lymphoma
3417	IDH1	isocitrate dehydrogenase 1 (NADP+), soluble	2q33.3	00984	5382	147700	NP_005887	NM_005896	ENSP00000260985	known	1	0	1	Last Universal Common Ancestor	12	2	Cellular metabolism	98	chr2	209101806	209116275	CGC,WES,WGS	glioblastoma,oligodendroglioma,prostate,acute myeloid leukemia
3418	IDH2	isocitrate dehydrogenase 2 (NADP+), mitochondrial	15q26.1	00973	5383	147650	NP_002159	NM_002168	-	known	1	0	0	Last Universal Common Ancestor	4	2	Cellular metabolism	96	chr15	90627501	90645622	CGC	glioblastoma
3437	IFIT3	interferon-induced protein with tetratricopeptide repeats 3	10q24	05228	5411	604650	NP_001026853;NP_001540	NM_001031683;NM_001549	ENSP00000360876;ENSP00000360883	candidate	0	0	0	Last Universal Common Ancestor	63	6	-1	54	chr10	91098416	91099882	WGS	glioblastoma,medulloblastoma
3482	IGF2R	insulin-like growth factor 2 receptor	6q26	00928	5467	147280	NP_000867	NM_000876	ENSP00000349437	candidate	0	0	0	Eukaryotes	31	8	Cellular processes,Signal transduction	89	chr6	160390279	160526113	WES	pancreas
3486	IGFBP3	insulin-like growth factor binding protein 3	7p13-p12	00899	5472	146732	NP_000589;NP_001013416	NM_000598;NM_001013398	ENSP00000275521	candidate	0	0	0	Vertebrates	36	5	Cell cycle,Cell motility and interactions,Cellular metabolism,Cellular processes,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction	95	chr7	45954422	45960739	WES	colorectal
3492	IGH@	immunoglobulin heavy locus	14q32.33	-	5477	-	-	-	-	known	1	0	-1	Vertebrates	0	0	-1	32	-	0	0	CGC	leukemia,lymphoma,myeloma,non-hodgkin lymphoma
50802	IGK@	immunoglobulin kappa locus	2p12	-	5715	-	-	-	-	known	1	0	-1	Vertebrates	18	0	-1	23	-	0	0	CGC	lymphoma,non-hodgkin lymphoma
3535	IGL@	immunoglobulin lambda locus	22q11.2	-	5853	-	-	-	-	known	1	0	-1	Eukaryotes	0	0	-1	90	-	0	0	CGC	lymphoma
285313	IGSF10	immunoglobulin superfamily, member 10	3q25.1	13732	26384	-	NP_001171616;NP_001171617;NP_849144	NM_001178145;NM_001178146;NM_178822	-	candidate	0	0	0	Eukaryotes	2	2	Cellular metabolism,Cellular processes,Development	-1	chr3	151154480	151176497	WES,WGS	pancreas,liver
283284	IGSF22	immunoglobulin superfamily, member 22	11p15.1	08229	26750	-	NP_775859	NM_173588	ENSP00000421191	candidate	0	0	0	Last Universal Common Ancestor	4	0	-1	-1	chr11	18726018	18745783	WES	colorectal
10320	IKZF1	IKAROS family zinc finger 1 (Ikaros)	7p13-p11.1	04318	13176	603023	NP_006051;NP_001207705;NP_001207704;NP_001207703;NP_001207698;NP_001207695;NP_001207702;NP_001207700;NP_001207699;NP_001207701;NP_001207697;NP_001207696;NP_001207694	NM_006060;NM_001220776;NM_001220775;NM_001220774;NM_001220769;NM_001220766;NM_001220773;NM_001220771;NM_001220770;NM_001220772;NM_001220768;NM_001220767;NM_001220765	ENSP00000342750;ENSP00000349928;ENSP00000342485;ENSP00000331614	known	1	1	0	Eukaryotes	7	1	Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription	78	chr7	50358658	50468322	CGC	leukemia,lymphoma
3586	IL10	interleukin 10	1q31-q32	00495	5962	124092	NP_000563	NM_000572	ENSP00000412237	candidate	0	0	0	Vertebrates	4	1	Cell cycle,Cell motility and interactions,Cell response to stimuli,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Immune system response,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	17	chr1	206941984	206945780	WGS	lymphoma
8809	IL18R1	interleukin 18 receptor 1	2q12	05138	5988	604494	NP_003846	NM_003855	ENSP00000233957	candidate	0	0	0	Eukaryotes	5	3	Immune system response,Signal transduction	7	chr2	102979121	103013343	WGS	prostate
3552	IL1A	interleukin 1, alpha	2q14	00988	5991	147760	NP_000566	NM_000575	-	candidate	0	0	0	Mammals	12	2	Cell cycle,Cell response to stimuli,Development,Immune system response,Regulation of intracellular processes and metabolism	53	chr2	113532647	113541347	HTMS	breast,lung,ovarian,pancreas,prostate
3553	IL1B	interleukin 1, beta	2q14	00985	5992	147720	NP_000567	NM_000576	ENSP00000263341	candidate	0	0	0	Vertebrates	16	1	Cell cycle,Cell motility and interactions,Cell response to stimuli,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Immune system response,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	67	chr2	113587941	113593806	HTMS,WES	breast,lung,ovarian,pancreas,prostate
9173	IL1RL1	interleukin 1 receptor-like 1	2q12	03123	5998	601203	NP_003847;NP_057316	NM_173459;NM_003856;NM_016232	ENSP00000386618;ENSP00000233954	candidate	0	0	0	Eukaryotes	26	1	Immune system response,Signal transduction	33	chr2	102954725	102968378	WGS	melanoma
3558	IL2	interleukin 2	4q26-q27	00979	6001	147680	NP_000577	NM_000586	-	known	1	0	0	Mammals	2	1	Cell cycle,Development,Immune system response,Regulation of intracellular processes and metabolism	10	chr4	123372910	123377595	CGC	lymphoma
53833	IL20RB	interleukin 20 receptor beta	3q22.3	14594	6004	605621	NP_653318	NM_144717	ENSP00000328133	candidate	0	0	0	Vertebrates	14	0	-1	-1	chr3	136676956	136729062	WGS	chronic lymphocytic leukemia
50615	IL21R	interleukin 21 receptor	16p11	05649	6006	605383	NP_068570;NP_851565;NP_851564	NM_021798;NM_181079;NM_181078	-	known	1	0	0	Vertebrates	5	5	Immune system response	12	chr16	27414492	27460601	CGC	non-hodgkin lymphoma
3561	IL2RG	interleukin 2 receptor, gamma	Xq13.1	02391	6010	308380	NP_000197	NM_000206	ENSP00000363318	candidate	0	0	0	Vertebrates	29	0	Signal transduction	80	chrX	70327589	70331389	WES	pancreas
3572	IL6ST	interleukin 6 signal transducer (gp130, oncostatin M receptor)	5q11.2	02824	6021	600694	NP_001177910;NP_002175;NP_786943	NM_001190981;NM_002184;NM_175767	ENSP00000370698;ENSP00000370687	known	1	0	0	Eukaryotes	43	4	Signal transduction	100	chr5	55236913	55272106	CGC	liver
3575	IL7R	interleukin 7 receptor	5p13	00893	6024	146661	NP_002176	NM_002185	ENSP00000306157	known	1	0	0	Vertebrates	1	1	DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	69	chr5	35857080	35876585	CGC	leukemia
92856	IMP4	IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast)	2q21.1	10002	30856	612981	NP_219484	NM_033416	ENSP00000386411	candidate	0	0	0	Last Universal Common Ancestor	34	1	DNA/RNA metabolism and transcription,Regulation of transcription	71	chr2	131100659	131104038	WES	glioblastoma
50939	IMPG2	interphotoreceptor matrix proteoglycan 2	3q12.2-q12.3	06135	18362	607056	NP_057331	NM_016247	-	candidate	0	0	0	Metazoans	0	0	-1	20	chr3	100947640	101039216	WGS	acute myeloid leukemia
3624	INHBA	inhibin, beta A	7p15-p13	00929	6066	147290	NP_002183	NM_002192	-	candidate	0	0	0	Metazoans	17	1	Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Immune system response,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	21	chr7	41729251	41739972	HTMS	lung
83729	INHBE	inhibin, beta E	12q13.3	11047	24029	612031	NP_113667	NM_031479	ENSP00000266646	candidate	0	0	0	Mammals	30	2	-1	11	chr12	57849320	57850628	WES	breast
3656	IRAK2	interleukin-1 receptor-associated kinase 2	3p25.3	04491	6113	603304	NP_001561	NM_001570	ENSP00000256458	candidate	0	0	0	Last Universal Common Ancestor	26	2	Cellular metabolism,Cellular processes,Immune system response,Signal transduction	-1	chr3	10206639	10283909	WGS	breast
51135	IRAK4	interleukin-1 receptor-associated kinase 4	12q12	06051	17967	606883	NP_001107654;NP_001138728;NP_057207;NP_001138730;NP_001138729	NM_001114182;NM_001145256;NM_016123;NM_001145258;NM_001145257	ENSP00000390327	candidate	0	0	0	Last Universal Common Ancestor	30	2	Cellular metabolism,Cellular processes,Signal transduction	40	chr12	44161915	44180363	HTMS	breast,lung,ovarian,pancreas,prostate
3660	IRF2	interferon regulatory factor 2	4q34.1-q35.1	00962	6117	147576	NP_002190	NM_002199	ENSP00000377218	candidate	0	0	0	Metazoans	13	1	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	66	chr4	185309915	185350218	WES	liver
3662	IRF4	interferon regulatory factor 4	6p25-p23	03543	6119	601900	NP_001182215;NP_002451	NM_001195286;NR_036585;NM_002460;NR_046000	ENSP00000370343	known	1	0	0	Metazoans	31	1	Cellular metabolism,DNA/RNA metabolism and transcription,Development,Immune system response,Regulation of intracellular processes and metabolism,Regulation of transcription	68	chr6	393153	407595	CGC,WES	myeloma,non-hodgkin lymphoma
3664	IRF6	interferon regulatory factor 6	1q32.3-q41	06227	6121	607199	NP_001193625;NP_006138	NM_001206696;NM_006147	ENSP00000355988	candidate	0	0	0	Metazoans	3	1	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	82	chr1	209961768	209974758	WES	head and neck squamous cell carcinoma
3394	IRF8	interferon regulatory factor 8	16q24.1	03336	5358	601565	NP_002154	NM_002163	ENSP00000268638	candidate	0	0	0	Vertebrates	30	0	Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription	86	chr16	85936622	85954885	WES	non-hodgkin lymphoma
3667	IRS1	insulin receptor substrate 1	2q36	00943	6125	147545	NP_005535	NM_005544	-	candidate	0	0	0	Metazoans	89	7	Cell response to stimuli,Regulation of intracellular processes and metabolism,Signal transduction	59	chr2	227659729	227663454	HTMS	sarcoma
8471	IRS4	insulin receptor substrate 4	Xq22.3	04620	6128	603510	NP_003595	NM_003604	ENSP00000361202	candidate	0	0	0	Metazoans	143	0	Signal transduction	41	chrX	107975804	107979574	WES	colorectal
79190	IRX6	iroquois homeobox 6	16q12.2	12091	14675	606196	NP_077311	NM_024335	-	candidate	0	0	0	Eukaryotes	0	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	-1	chr16	55359004	55363222	WES	glioblastoma
9798	IST1	increased sodium tolerance 1 homolog (yeast)	16q22.2	13784	28977	-	NP_055576	NM_014761	-	known	0	0	1	Eukaryotes	17	2	-1	101	chr16	71949544	71961699	CGC,Amplified	
83737	ITCH	itchy E3 ubiquitin protein ligase homolog (mouse)	20q11.22	-	13890	606409	NP_113671	NM_031483	ENSP00000363998	candidate	0	0	0	Eukaryotes	129	1	Cell cycle,Cell motility and interactions,Cellular metabolism,Cellular processes,Immune system response,Other,Regulation of intracellular processes and metabolism	66	chr20	32981618	33095596	HTMS	breast,lung,ovarian,pancreas,prostate
3682	ITGAE	integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)	17p13	05249	6147	604682	NP_002199	NM_002208	ENSP00000263087	candidate	0	0	0	Eukaryotes	5	0	Signal transduction	103	chr17	3618144	3680952	WES	colorectal
27231	ITGB1BP3	integrin beta 1 binding protein 3	19p13.3	16371	17871	608705	NP_733778	NM_014446;NM_170678	ENSP00000168977	candidate	0	0	0	Last Universal Common Ancestor	9	3	Cellular metabolism,DNA/RNA metabolism and transcription	43	chr19	3936574	3942268	WES	melanoma
3699	ITIH3	inter-alpha-trypsin inhibitor heavy chain 3	3p21.1	00891	6168	146650	NP_002208	NM_002217	ENSP00000415769	candidate	0	0	0	Last Universal Common Ancestor	2	0	Cellular metabolism	30	chr3	52828820	52842694	WGS	liver
3702	ITK	IL2-inducible T-cell kinase	5q31-q32	01746	6171	186973	NP_005537	NM_005546	ENSP00000398655	known	1	0	0	Last Universal Common Ancestor	37	0	Cell response to stimuli,Cellular metabolism,Cellular processes,Signal transduction	81	chr5	156607989	156679685	CGC,HTMS	lymphoma,breast,lung,ovarian,pancreas,prostate
55600	ITLN1	intelectin 1 (galactofuranose binding)	1q21.3	17165	18259	609873	NP_060095	NM_017625	ENSP00000323587	candidate	0	0	1	Metazoans	1	0	Cell response to stimuli,Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction	-1	chr1	160846457	160854667	WES	melanoma
3710	ITPR3	inositol 1,4,5-trisphosphate receptor, type 3	6p21	00926	6182	147267	NP_002215	NM_002224	ENSP00000363435	candidate	0	0	0	Eukaryotes	22	0	Cellular processes,Signal transduction	68	chr6	33589380	33663554	HTMS	breast,lung,ovarian,pancreas,prostate
3716	JAK1	Janus kinase 1	1p32.3-p31.3	00992	6190	147795	NP_002218	NM_002227	ENSP00000343204	known	1	0	0	Last Universal Common Ancestor	98	4	Cellular metabolism,Cellular processes,Signal transduction	107	chr1	65300248	65349161	CGC,WGS	leukemia,prostate
3717	JAK2	Janus kinase 2	9p24	00993	6192	147796	NP_004963	NM_004972	ENSP00000371067	known	1	0	0	Last Universal Common Ancestor	128	4	Cell cycle,Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction	29	chr9	5021988	5126788	CGC,WGS	leukemia,myeloma,breast,liver
3718	JAK3	Janus kinase 3	19p13.1	02547	6193	600173	NP_000206	NM_000215	ENSP00000391676	known	1	0	0	Last Universal Common Ancestor	47	1	Cellular metabolism,Cellular processes	66	chr19	17937555	17955226	CGC	leukemia
282973	JAKMIP3	Janus kinase and microtubule interacting protein 3	10q26.3	12574	23523	611198	NP_001098991	NM_001104947;NM_194303;NM_001105521	ENSP00000298622	candidate	0	0	0	Metazoans	22	1	-1	-1	chr10	133918313	133978239	WGS	glioblastoma
3720	JARID2	jumonji, AT rich interactive domain 2	6p24-p23	03355	6196	601594	NP_004964	NM_004973	ENSP00000341280	candidate	0	0	0	Eukaryotes	10	11	Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription	108	chr6	15246771	15520479	WGS	melanoma
221895	JAZF1	JAZF zinc finger 1	7p15.2-p15.1	09373	28917	606246	NP_778231	NM_175061	ENSP00000283928	known	1	0	0	Opisthokonts	2	2	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	-1	chr7	27872422	28220196	CGC	endometrium
51528	JKAMP	JNK1/MAPK8-associated membrane protein	14q23.1	12623	20184	611176	NP_001092095;NP_057559	NM_001098625;NM_016475	-	candidate	0	0	0	Metazoans	7	0	-1	-1	chr14	59953430	59970787	WES	breast
126306	JSRP1	junctional sarcoplasmic reticulum protein 1	19p13.3	08724	24963	608743	NP_653217	NM_144616	ENSP00000300961	candidate	0	0	0	Mammals	0	0	-1	-1	chr19	2252331	2255313	WGS	lymphoma
3725	JUN	jun proto-oncogene	1p32-p31	01302	6204	165160	NP_002219	NM_002228	ENSP00000360266	known	1	0	0	Opisthokonts	56	7	Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription	106	chr1	59247750	59248742	CGC,Amplified	sarcoma
8997	KALRN	kalirin, RhoGEF kinase	3q21.2	12169	4814	604605	NP_003938;NP_008995;NP_001019831	NM_003947;NM_007064;NM_001024660;NR_028136	ENSP00000353109;ENSP00000240874;ENSP00000291478	candidate	0	0	0	Eukaryotes	25	1	Cellular metabolism,Cellular processes,Development,Signal transduction	63	chr3	123813685	124438314	WES	colorectal
7994	KAT6A	K(lysine) acetyltransferase 6A	8p11	03244	13013	601408	NP_006757;NP_001092883;NP_001092882	NM_006766;NM_001099413;NM_001099412	ENSP00000380136;ENSP00000385888;ENSP00000265713	known	1	0	0	Eukaryotes	31	2	Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription	106	chr8	41789726	41906495	CGC	leukemia
23522	KAT6B	K(lysine) acetyltransferase 6B	10q22.2	07065	17582	605880	NP_036462	NM_012330	ENSP00000361796;ENSP00000361809;ENSP00000287239	known	1	0	0	Eukaryotes	1	3	Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	100	chr10	76602616	76790801	CGC	leukemia
23254	KAZN	kazrin, periplakin interacting protein	1p36.21	11122	29173	-	NP_056024;NP_001018001;NP_963922;NP_001017999;NP_001018000	NM_015209;NM_001018001;NM_201628;NM_001017999;NM_001018000	ENSP00000354727;ENSP00000383602;ENSP00000391728;ENSP00000365198	candidate	0	0	0	Metazoans	7	0	Development	74	chr1	14925494	15441128	WGS	liver
9920	KBTBD11	kelch repeat and BTB (POZ) domain containing 11	8p23.3	17195	29104	-	NP_055682	NM_014867	ENSP00000321544	candidate	0	0	0	Eukaryotes	1	3	-1	49	chr8	1949359	1951227	WES	pancreas
3742	KCNA6	potassium voltage-gated channel, shaker-related subfamily, member 6	12p13	08884	6225	176257	NP_002226	NM_002235	ENSP00000408321	candidate	0	0	1	Last Universal Common Ancestor	1	0	Cellular processes	44	chr12	4919208	4920794	WES	head and neck squamous cell carcinoma
7881	KCNAB1	potassium voltage-gated channel, shaker-related subfamily, beta member 1	3q26.1	03089	6228	601141	NP_751891;NP_751892;NP_003462	NM_172159;NM_172160;NM_003471	ENSP00000418956;ENSP00000305858;ENSP00000419952	candidate	0	0	0	Last Universal Common Ancestor	112	0	Cellular processes	59	chr3	155838401	156254533	WES	chronic lymphocytic leukemia
3747	KCNC2	potassium voltage-gated channel, Shaw-related subfamily, member 2	12q14.1	08883	6234	176256	NP_631875;NP_631874;NP_715624	NM_139137;NM_139136;NM_153748	ENSP00000340121;ENSP00000298972;ENSP00000449253;ENSP00000319877	candidate	0	0	0	Last Universal Common Ancestor	1	0	Cellular processes	3	chr12	75436888	75601763	WGS	lung,melanoma
93107	KCNG4	potassium voltage-gated channel, subfamily G, member 4	16q24.1	16253	19697	607603	NP_758857	NM_172347;NM_133490	-	candidate	0	0	0	Last Universal Common Ancestor	3	0	Cellular processes	-1	chr16	84255826	84271091	WGS	breast
3768	KCNJ12	potassium inwardly-rectifying channel, subfamily J, member 12	17p11.2	09083	6258	602323	NP_066292	NM_021012	ENSP00000463778	candidate	0	0	-1	Last Universal Common Ancestor	0	0	Cellular processes,Multicellular activities	16	-	0	0	WGS	lymphoma
3782	KCNN3	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3	1q21.3	04283	6292	602983	NP_001191016;NP_002240;NP_740752	NM_001204087;NM_002249;NM_170782	-	candidate	0	0	0	Eukaryotes	3	0	Cellular processes,Development,Multicellular activities	0	chr1	154680455	154842440	WGS	lung
3786	KCNQ3	potassium voltage-gated channel, KQT-like subfamily, member 3	8q24	09077	6297	602232	NP_001191753;NP_004510	NM_001204824;NM_004519	-	candidate	0	0	0	Last Universal Common Ancestor	7	0	Cellular processes,Multicellular activities	31	chr8	133141512	133492779	WGS	prostate
56479	KCNQ5	potassium voltage-gated channel, KQT-like subfamily, member 5	6q14	16241	6299	607357	NP_001153605;NP_001153604;NP_062816;NP_001153606;NP_001153602	NM_001160133;NM_001160132;NM_019842;NM_001160134;NM_001160130	ENSP00000345055;ENSP00000359425	candidate	0	0	0	Last Universal Common Ancestor	16	0	Cellular processes,Multicellular activities	-1	chr6	73331918	73905134	WES	colorectal
57582	KCNT1	potassium channel, subfamily T, member 1	9q34.3	-	18865	608167	NP_065873	NM_020822	ENSP00000360822	candidate	0	0	0	Last Universal Common Ancestor	0	0	Cellular processes	-1	chr9	138594105	138684004	WGS	prostate
386617	KCTD8	potassium channel tetramerisation domain containing 8	4p13	13771	22394	-	NP_938167	NM_198353	ENSP00000353129	candidate	0	0	0	Eukaryotes	1	0	Cellular processes	-1	chr4	44176810	44450540	WES	head and neck squamous cell carcinoma
84678	KDM2B	lysine (K)-specific demethylase 2B	12q24.31	12362	13610	609078	NP_001005366;NP_115979	NM_001005366;NM_032590	ENSP00000366269;ENSP00000366271	candidate	0	0	0	Eukaryotes	18	2	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	-1	chr12	121868094	122018816	WES	lymphoma
55818	KDM3A	lysine (K)-specific demethylase 3A	2p11.2	11054	20815	611512	NP_060903;NP_001140160	NM_018433;NM_001146688	ENSP00000386516;ENSP00000323659	candidate	0	0	0	Eukaryotes	11	0	Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	98	chr2	86669171	86719239	WGS	chronic lymphocytic leukemia
5927	KDM5A	lysine (K)-specific demethylase 5A	12p11	08915	9886	180202	NP_001036068	NM_005056;NM_001042603	ENSP00000382688	known	1	0	0	Eukaryotes	2	1	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	81	chr12	394625	498257	CGC	leukemia
10765	KDM5B	lysine (K)-specific demethylase 5B	1q32.1	09251	18039	605393	NP_006609	NM_006618	ENSP00000356234	candidate	0	0	0	Eukaryotes	2	2	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	96	chr1	202698167	202777433	WES	breast
8242	KDM5C	lysine (K)-specific demethylase 5C	Xp11.22-p11.21	02442	11114	314690	NP_004178;NP_001140174	NM_004187;NM_001146702	ENSP00000445176;ENSP00000364550	known	0	1	1	Eukaryotes	19	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	86	chrX	53222152	53254071	CGC,HTMS,WES	kidney
7403	KDM6A	lysine (K)-specific demethylase 6A	Xp11.2	02131	12637	300128	NP_066963	NM_021140	ENSP00000367203	known	0	1	1	Last Universal Common Ancestor	31	0	DNA/RNA metabolism and transcription	69	chrX	44732798	44969494	CGC,HTMS,WES,WGS	kidney,myeloma,oesophageal,medulloblastoma,prostate
3791	KDR	kinase insert domain receptor (a type III receptor tyrosine kinase)	4q11-q12	01867	6307	191306	NP_002244	NM_002253	ENSP00000263923	known	1	0	0	Last Universal Common Ancestor	64	3	Cellular metabolism,Cellular processes,Development,Signal transduction	49	chr4	55946111	55991460	CGC,HTMS	lung,sarcoma,breast,ovarian,pancreas,prostate
2531	KDSR	3-ketodihydrosphingosine reductase	18q21.3	00640	4021	136440	NP_002026	NM_002035	ENSP00000385083	known	1	0	0	Last Universal Common Ancestor	1	6	-1	89	chr18	60999018	61034351	CGC	non-hodgkin lymphoma
9817	KEAP1	kelch-like ECH-associated protein 1	19p13.2	12079	23177	606016	NP_036421;NP_987096	NM_012289;NM_203500	ENSP00000377245;ENSP00000171111	candidate	0	0	0	Last Universal Common Ancestor	90	4	Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription	47	chr19	10597331	10610709	HTMS,WES	breast,lung,ovarian,pancreas,prostate
202559	KHDRBS2	KH domain containing, RNA binding, signal transduction associated 2	6q11.1	13775	18114	610487	NP_689901	NM_152688	ENSP00000281156	candidate	0	0	0	Eukaryotes	57	2	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	24	chr6	62390871	62995853	WES,WGS	melanoma,liver
23351	KHNYN	KH and NYN domain containing	14q12	11076	20166	-	NP_056114	NM_015299	ENSP00000251343	candidate	0	0	0	Eukaryotes	6	2	-1	97	chr14	24899937	24906488	WGS	liver
8570	KHSRP	KH-type splicing regulatory protein	19p13.3	10350	6316	603445	NP_003676	NM_003685	ENSP00000381216	candidate	0	0	1	Eukaryotes	15	4	Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	103	chr19	6415149	6424712	WES	lung
23199	KIAA0182	KIAA0182	16q24.1	11066	28979	-	NP_001127945;NP_055430	NM_001134473;NM_014615	ENSP00000376934;ENSP00000253458	candidate	0	0	0	Metazoans	12	1	-1	101	chr16	85667519	85706142	WES	colorectal
23247	KIAA0556	KIAA0556	16p12.1	13806	29068	-	NP_056017	NM_015202	ENSP00000261588	candidate	0	0	0	Eukaryotes	1	0	-1	75	chr16	27585221	27789947	WES	colorectal
23277	KIAA0664	KIAA0664	17p13.3	10014	29094	-	NP_056044	NM_015229	ENSP00000388872	candidate	0	0	0	Last Universal Common Ancestor	331	4	Cellular metabolism,Regulation of transcription	97	chr17	2593891	2607844	WES	breast
23379	KIAA0947	KIAA0947	5p15.32	-	29154	-	NP_056140	NM_015325	ENSP00000296564	candidate	0	0	0	Metazoans	8	1	-1	89	chr5	5423029	5489440	WGS	prostate
23251	KIAA1024	KIAA1024	15q25.1	17206	29172	-	NP_056021	NM_015206	ENSP00000307461	candidate	0	0	0	Vertebrates	0	1	-1	8	chr15	79748490	79760723	WES	pancreas
57462	KIAA1161	KIAA1161	9p13.3	17208	19918	-	NP_065753	NM_020702	-	candidate	0	0	0	Last Universal Common Ancestor	1	1	-1	-1	chr9	34370800	34372941	WGS	glioblastoma
57535	KIAA1324	KIAA1324	1p13.3	13850	29618	611298	NP_065826	NM_020775	-	candidate	0	0	0	Eukaryotes	0	1	-1	66	chr1	109656806	109745631	WGS	chronic lymphocytic leukemia
57614	KIAA1468	KIAA1468	18q21.33	13866	29289	-	NP_065905	NM_020854	ENSP00000381198	candidate	0	0	0	Eukaryotes	1	0	-1	-1	chr18	59854739	59972764	WGS	breast
57670	KIAA1549	KIAA1549	7q34	-	22219	613344	NP_001158137;NP_065961	NM_001164665;NM_020910	ENSP00000406661	known	1	0	0	Metazoans	18	3	-1	25	chr7	138522654	138666015	CGC	pilocytic astrocytoma
85452	KIAA1751	KIAA1751	1p36.33	-	29368	-	NP_001073953	NM_001080484	ENSP00000270720	candidate	0	0	0	Metazoans	0	0	-1	57	chr1	1887020	1922395	WES,WGS	pancreas,glioblastoma
84451	KIAA1804	mixed lineage kinase 4	1q42	10087	-	-	NP_115811	NM_032435	ENSP00000355583	candidate	0	0	0	Last Universal Common Ancestor	10	6	Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction	-1	chr1	233463775	233518454	WES	colorectal (non-hypermutated),glioblastoma
340533	KIAA2022	KIAA2022	Xq13.3	15957	29433	300524	NP_001008537	NM_001008537	ENSP00000055682	candidate	0	0	0	Eukaryotes	2	0	-1	-1	chrX	73959243	73965485	WES	colorectal
9928	KIF14	kinesin family member 14	1q32.1	06605	19181	611279	NP_055690	NM_014875	ENSP00000356319	candidate	0	0	0	Eukaryotes	2	6	Cellular processes	40	chr1	200522519	200587851	WES	breast
547	KIF1A	kinesin family member 1A	2q37.3	03156	888	601255	NP_004312;NP_001230937	NM_004321;NM_001244008	ENSP00000438388;ENSP00000322791	candidate	0	0	0	Eukaryotes	1	0	Cellular processes	38	chr2	241656784	241737169	WGS	lung
23095	KIF1B	kinesin family member 1B	1p36.2	05818	16636	605995	NP_055889;NP_904325	NM_015074;NM_183416	ENSP00000366290;ENSP00000366297	candidate	0	0	0	Eukaryotes	21	10	Cellular processes,Multicellular activities	63	chr1	10292387	10436642	WES	lymphoma
10749	KIF1C	kinesin family member 1C	17p13.2	04342	6317	603060	NP_006603	NM_006612	ENSP00000320821	candidate	0	0	0	Eukaryotes	17	1	Cellular processes	15	chr17	4903542	4927443	WGS	breast
55605	KIF21A	kinesin family member 21A	12q12	10506	19349	608283	NP_001166936;NP_060111;NP_001166934;NP_001166935	NM_001173465;NM_017641;NM_001173463;NM_001173464	ENSP00000379029;ENSP00000354851	candidate	0	0	0	Last Universal Common Ancestor	5	1	Cellular processes	-1	chr12	39688229	39836772	WES,WGS	lung
55582	KIF27	kinesin family member 27	9q21.32	11179	18632	611253	NP_060046	NM_017576	ENSP00000297814	candidate	0	0	0	Eukaryotes	6	1	Cellular processes	-1	chr9	86451919	86530506	HTMS	breast,lung,ovarian,pancreas,prostate
3799	KIF5B	kinesin family member 5B	10p11.22	07214	6324	602809	NP_004512	NM_004521	ENSP00000307078	known	1	0	0	Eukaryotes	29	12	Cellular processes	109	chr10	32304460	32344901	CGC	lung
3811	KIR3DL1	killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 1	19q13.4	10034	6338	604946	XP_003403454;NP_037421	XM_003403406;NM_013289	ENSP00000375608	candidate	0	0	5	Mammals	3	1	-1	33	chr19	55236002	55341727	WGS	chronic lymphocytic leukemia
3815	KIT	v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog	4q11-q12	01287	6342	164920	NP_000213;NP_001087241	NM_000222;NM_001093772	ENSP00000288135	known	1	0	0	Last Universal Common Ancestor	73	5	Cell cycle,Cellular metabolism,Cellular processes,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction	71	chr4	55524182	55604720	CGC,HTMS,Amplified	gastric,leukemia,mastocytosis,melanoma,testis,sarcoma
28999	KLF15	Kruppel-like factor 15	3q21.3	07568	14536	606465	NP_054798	NM_014079	ENSP00000296233	candidate	0	0	0	Last Universal Common Ancestor	3	0	Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	54	chr3	126062573	126071765	WGS	lung
10365	KLF2	Kruppel-like factor 2 (lung)	19p13.11	03602	6347	602016	NP_057354	NM_016270	ENSP00000248071	candidate	0	0	0	Last Universal Common Ancestor	28	3	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	102	chr19	16435735	16437839	WES	lymphoma
1316	KLF6	Kruppel-like factor 6	10p15	03632	2235	602053	NP_001153596;NP_001153597;NP_001291	NM_001008490;NM_001160124;NR_027653;NM_001160125;NM_001300	ENSP00000445301;ENSP00000419923	known	0	1	0	Last Universal Common Ancestor	20	5	Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Immune system response,Regulation of intracellular processes and metabolism,Regulation of transcription	86	chr10	3821734	3827206	CGC	glioma,prostate
54758	KLHDC4	kelch domain containing 4	16q24.3	11180	25272	-	NP_060036;NP_001171783;NP_001171785	NM_017566;NM_001184854;NM_001184856	ENSP00000262530;ENSP00000325717;ENSP00000270583	candidate	0	0	0	Last Universal Common Ancestor	8	2	-1	77	chr16	87741960	87799496	WES	pancreas
56062	KLHL4	kelch-like 4 (Drosophila)	Xq21.3	02283	6355	300348	NP_061990;NP_476503	NM_019117;NM_057162	ENSP00000362211;ENSP00000362206	candidate	0	0	0	Eukaryotes	10	1	-1	37	chrX	86772897	86924391	WGS	breast
89857	KLHL6	kelch-like 6 (Drosophila)	3q27.3	10035	18653	614214	NP_569713	NM_130446	ENSP00000341342	candidate	0	0	0	Last Universal Common Ancestor	2	0	-1	-1	chr3	183209718	183273441	WES,WGS	lymphoma,non-hodgkin lymphoma,chronic lymphocytic leukemia
3817	KLK2	kallikrein-related peptidase 2	19q13.41	01006	6363	147960	NP_001243009;NP_005542;NP_001002231	NR_045762;NM_001256080;NM_005551;NM_001002232;NM_001002231;NR_045763	ENSP00000350748;ENSP00000313581	known	1	0	1	Last Universal Common Ancestor	15	0	Cellular metabolism	28	chr19	51376730	51381812	CGC	prostate
85442	KNDC1	kinase non-catalytic C-lobe domain (KIND) containing 1	10q26.3	13931	29374	-	NP_689856	NM_152643	ENSP00000304437	candidate	0	0	0	Eukaryotes	2	0	Signal transduction	-1	chr10	134973972	135038391	WGS	acute myeloid leukemia
3841	KPNA5	karyopherin alpha 5 (importin alpha 6)	6q22.1	05179	6398	604545	NP_002260	NM_002269	ENSP00000348704	candidate	0	0	2	Eukaryotes	13	4	Cellular processes	16	chr6	117010482	117053483	WES	breast
3845	KRAS	v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog	12p12.1	01817	6407	190070	NP_203524;NP_004976	NM_033360;NM_004985	ENSP00000308495	known	1	0	2	Last Universal Common Ancestor	40	14	Cell cycle,Cell response to stimuli,Cellular processes,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction	106	chr12	25368378	25398318	CGC,HTMS,WES,WGS,Amplified	colorectal,leukemia,lung,other,pancreas,thyroid,breast,ovarian,prostate,bladder,cholangiocarcinoma,colorectal (non-hypermutated),myelodysplasia,myeloma
83999	KREMEN1	kringle containing transmembrane protein 1	22q12.1	11182	17550	609898	NP_114434;NP_001034659	NM_032045;NM_001039570;NM_153379	ENSP00000383189;ENSP00000331242	candidate	0	0	0	Eukaryotes	2	1	Signal transduction	-1	chr22	29469119	29538088	HTMS	breast,lung,ovarian,pancreas,prostate
3881	KRT31	keratin 31	17q12-q21	03047	6448	601077	NP_002268	NM_002277	ENSP00000251645	candidate	0	0	4	Eukaryotes	33	0	Development	32	chr17	39550271	39553791	WGS	chronic lymphocytic leukemia
319101	KRT73	keratin 73	12q13.3	16304	28928	608247	NP_778238	NM_175068	ENSP00000307014	candidate	0	0	2	Eukaryotes	9	0	-1	-1	chr12	53001983	53012308	WES	colorectal
338785	KRT79	keratin 79	12q13.13	11183	28930	611160	NP_787028	NM_175834	ENSP00000328358	candidate	0	0	0	Eukaryotes	22	0	-1	-1	chr12	53215659	53228044	WES	acute myeloid leukemia
353332	KRTAP12-1	keratin associated protein 12-1	21q22.3	11197	20529	-	NP_859014	NM_181686	ENSP00000375475	candidate	0	0	3	Mammals	0	0	-1	-1	chr21	46101751	46102038	WES	melanoma
387264	KRTAP5-1	keratin associated protein 5-1	11p15.5	13948	23596	148022	NP_001005922	NM_001005922	ENSP00000371606	candidate	0	0	-1	-	30	0	-1	-1	-	0	0	WGS	lymphoma
439915	KRTAP5-5	keratin associated protein 5-5	11p15.5	-	23601	-	NP_001001480	NM_001001480	ENSP00000382584	candidate	0	0	7	-	1	0	-1	-1	chr11	1651071	1651781	WES,WGS	lymphoma
8844	KSR1	kinase suppressor of ras 1	17q11.1-q11.2	-	6465	601132	NP_055053	NM_014238	-	candidate	0	0	0	Last Universal Common Ancestor	18	0	Cellular metabolism,Cellular processes,Signal transduction	37	chr17	25904557	25944455	WGS	melanoma
3895	KTN1	kinectin 1 (kinesin receptor)	14q22.1	02661	6467	600381	NP_001072990;NP_004977;NP_001072989;NP_891556	NM_001079522;NM_004986;NM_001079521;NM_182926	ENSP00000378725;ENSP00000394992;ENSP00000391964	known	1	0	0	Eukaryotes	25	1	Cellular processes	107	chr14	56078767	56146402	CGC	thyroid
284217	LAMA1	laminin, alpha 1	18p11.3	01033	6481	150320	NP_005550	NM_005559	ENSP00000374309	candidate	0	0	0	Eukaryotes	24	3	Cell cycle,Cell motility and interactions,Development,Regulation of intracellular processes and metabolism	11	chr18	6942081	7117719	WES	breast,colorectal
3908	LAMA2	laminin, alpha 2	6q22-q23	01125	6482	156225	NP_000417;NP_001073291	NM_000426;NM_001079823	ENSP00000400365	candidate	0	0	0	Last Universal Common Ancestor	9	0	Cell motility and interactions,Development	76	chr6	129204391	129837489	WES	cholangiocarcinoma
3910	LAMA4	laminin, alpha 4	6q21	02532	6484	600133	NP_001098678;NP_002281;NP_001098677;NP_001098676;NP_001098679	NM_001105208;NM_002290;NM_001105207;NM_001105206;NM_001105209	ENSP00000230538;ENSP00000429488;ENSP00000398226;ENSP00000374114	candidate	0	0	0	Eukaryotes	34	3	Cell motility and interactions,Development	95	chr6	112430643	112575352	WES	bladder
3927	LASP1	LIM and SH3 protein 1	17q11-q21.3	04229	6513	602920	NP_006139	NM_006148	ENSP00000325240	known	1	0	0	Eukaryotes	22	7	Cellular processes	109	chr17	37026443	37075028	CGC	leukemia
3932	LCK	lymphocyte-specific protein tyrosine kinase	1p34.3	01080	6524	153390	NP_005347;NP_001036236	NM_005356;NM_001042771	ENSP00000328213;ENSP00000337825	known	1	0	0	Last Universal Common Ancestor	196	1	Cell cycle,Cell response to stimuli,Cellular metabolism,Cellular processes,Development,Immune system response,Regulation of intracellular processes and metabolism,Signal transduction	25	chr1	32739931	32751314	CGC	leukemia
392399	LCN9	lipocalin 9	9q34.3	13979	17442	612903	NP_001001676	NM_001001676	ENSP00000277526	candidate	0	0	0	Mammals	0	1	-1	-1	chr9	138555168	138557756	WES	colorectal
3936	LCP1	lymphocyte cytosolic protein 1 (L-plastin)	13q14.3	01082	6528	153430	NP_002289	NM_002298	ENSP00000315757	known	1	0	1	Eukaryotes	9	2	Cellular processes	70	chr13	46701729	46733797	CGC	non-hodgkin lymphoma
8861	LDB1	LIM domain binding 1	10q24-q25	09144	6532	603451	NP_001106878;NP_003884	NM_001113407;NM_003893	ENSP00000392466;ENSP00000354616	candidate	0	0	0	Eukaryotes	48	0	Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription	59	chr10	103867853	103871294	WES	medulloblastoma
388633	LDLRAD1	low density lipoprotein receptor class A domain containing 1	1p32.3	17372	32069	-	NP_001010978	NM_001010978	ENSP00000360411	candidate	0	0	0	Vertebrates	0	0	-1	-1	chr1	54474658	54483103	WES	melanoma
64175	LEPRE1	leucine proline-enriched proteoglycan (leprecan) 1	1p34.1	11227	19316	610339	NP_001139761;NP_001230175;NP_071751	NM_001146289;NM_001243246;NM_022356	ENSP00000380245;ENSP00000236040;ENSP00000296388	candidate	0	0	0	Eukaryotes	14	0	Cell cycle,Regulation of intracellular processes and metabolism	92	chr1	43212586	43232642	WGS	lung
55214	LEPREL1	leprecan-like 1	3q28	17270	19317	610341	NP_060662;NP_001127890	NM_018192;NM_001134418	ENSP00000408947;ENSP00000316881	candidate	0	0	0	Eukaryotes	0	0	-1	28	chr3	189675704	189838520	WGS	breast
3954	LETM1	leucine zipper-EF-hand containing transmembrane protein 1	4p16.3	05101	6556	604407	NP_036450	NM_012318	ENSP00000305653	candidate	0	0	2	Eukaryotes	10	4	Signal transduction	66	chr4	1816154	1850937	WGS	melanoma
59352	LGR6	leucine-rich repeat containing G protein-coupled receptor 6	1q32.1	05974	19719	606653	NP_067649;NP_001017403;NP_001017404	NM_021636;NM_001017403;NM_001017404	ENSP00000356247;ENSP00000387869;ENSP00000255432	candidate	0	0	0	Last Universal Common Ancestor	1	1	Signal transduction	-1	chr1	202163118	202288332	WES	colorectal
10186	LHFP	lipoma HMGIC fusion partner	13q12	09464	6586	606710	NP_005771	NM_005780	ENSP00000368908	known	1	0	0	Metazoans	2	2	-1	84	chr13	39918076	40175353	CGC	lipoma
3977	LIFR	leukemia inhibitory factor receptor alpha	5p13-p12	01048	6597	151443	NP_001121143;NP_002301	NM_001127671;NM_002310	ENSP00000263409	known	1	0	0	Eukaryotes	16	10	Cell cycle,Regulation of intracellular processes and metabolism,Signal transduction	29	chr5	38481700	38530749	CGC	salivary
10859	LILRB1	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1	19q13.4	07273	6605	604811	NP_001075107;NP_006660;NP_001075108;NP_001075106	NM_001081638;NM_006669;NM_001081639;NM_001081637	ENSP00000315997;ENSP00000379618;ENSP00000379623;ENSP00000379622	candidate	0	0	3	Vertebrates	79	0	Cell response to stimuli	24	chr19	55085542	55148326	WES	head and neck squamous cell carcinoma
84894	LINGO1	leucine rich repeat and Ig domain containing 1	15q24.3	14322	21205	609791	NP_116197	NM_032808	ENSP00000347451	candidate	0	0	0	Last Universal Common Ancestor	7	0	-1	-1	chr15	77906389	77908245	WGS	lung
9516	LITAF	lipopolysaccharide-induced TNF factor	16p13.13	10354	16841	603795	NP_001129945;NP_004853;NP_001129944	NM_001136473;NM_004862;NM_001136472;NR_024320	ENSP00000397958;ENSP00000340118	candidate	0	0	0	Eukaryotes	14	10	Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	107	chr16	11643496	11650586	WGS	liver
3996	LLGL1	lethal giant larvae homolog 1 (Drosophila)	17p11.2	02982	6628	600966	NP_004131	NM_004140	ENSP00000321537	candidate	0	0	0	Eukaryotes	25	4	Cellular processes,Development	38	chr17	18128997	18146132	WGS	chronic lymphocytic leukemia
4004	LMO1	LIM domain only 1 (rhombotin 1)	11p15	01738	6641	186921	NP_002306	NM_002315	ENSP00000404538;ENSP00000338207	known	1	0	1	Eukaryotes	0	0	-1	35	chr11	8246166	8252052	CGC	leukemia,neuroblastoma
4005	LMO2	LIM domain only 2 (rhombotin-like 1)	11p13	01586	6642	180385	NP_001135787;NP_001135788;NP_005565	NM_001142315;NM_001142316;NM_005574	ENSP00000379175;ENSP00000257818	known	1	0	0	Eukaryotes	22	1	-1	94	chr11	33880905	33891136	CGC	leukemia
4008	LMO7	LIM domain 7	13q22.2	05078	6646	604362	NP_056667;NP_005349	NM_015842;NM_005358;NM_015843	ENSP00000342112;ENSP00000433352	candidate	0	0	0	Eukaryotes	21	3	Cellular metabolism,Cellular processes	21	chr13	76378463	76432146	WES,WGS	colorectal,glioblastoma
4009	LMX1A	LIM homeobox transcription factor 1, alpha	1q24.1	02623	6653	600298	NP_001167540;NP_796372	NM_001174069;NM_001033507;NM_177399;NM_177398	ENSP00000294816;ENSP00000340226	candidate	0	0	0	Eukaryotes	6	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	-1	chr1	165173120	165324796	WES	glioblastoma
392232	LOC392232	transient receptor potential cation channel, subfamily A, member 1 pseudogene	8q13.3	-	-	-	-	NR_033867	-	candidate	0	0	-1	-	0	0	-1	-1	-	0	0	WES	melanoma
22859	LPHN1	latrophilin 1	19p13.2	14305	20973	-	NP_055736;NP_001008701	NM_014921;NM_001008701	-	candidate	0	0	0	Eukaryotes	12	4	Signal transduction	76	chr19	14261688	14294414	WES	pancreas
23266	LPHN2	latrophilin 2	1p31.1	06116	18582	607018	NP_036434	NM_012302	ENSP00000322270	candidate	0	0	0	Eukaryotes	2	4	Signal transduction	67	chr1	82302670	82456826	WES	chronic lymphocytic leukemia
23284	LPHN3	latrophilin 3	4q13.1	10055	20974	-	NP_056051	NM_015236	ENSP00000439831	candidate	0	0	0	Eukaryotes	17	0	Signal transduction	56	chr4	62363012	62936623	HTMS,WES	breast,lung,ovarian,pancreas,prostate,chronic lymphocytic leukemia
4026	LPP	LIM domain containing preferred translocation partner in lipoma	3q28	02828	6679	600700	NP_001161143;NP_001161144;NP_005569	NM_001167671;NM_001167672;NM_005578	ENSP00000438891;ENSP00000318089	known	1	0	0	Eukaryotes	19	3	-1	97	chr3	188123909	188592264	CGC	leukemia,lipoma
987	LRBA	LPS-responsive vesicle trafficking, beach and anchor containing	4q31.3	07344	1742	606453	NP_001186211;NP_006717	NM_001199282;NM_006726	ENSP00000421552;ENSP00000349629	candidate	0	0	0	Eukaryotes	6	0	-1	99	chr4	151186877	151935794	WES	breast
145581	LRFN5	leucine rich repeat and fibronectin type III domain containing 5	14q21.1	17445	20360	612811	NP_689660	NM_152447	ENSP00000298119	candidate	0	0	0	Eukaryotes	0	0	-1	-1	chr14	42355829	42368163	WES	head and neck squamous cell carcinoma,pancreas
121227	LRIG3	leucine-rich repeats and immunoglobulin-like domains 3	12q14.1	08317	30991	608870	NP_001129523;NP_700356	NM_001136051;NM_153377	ENSP00000368436;ENSP00000326759	known	1	0	0	Last Universal Common Ancestor	1	3	-1	-1	chr12	59266357	59314016	CGC	lung
53353	LRP1B	low density lipoprotein receptor-related protein 1B	2q21.2	16383	6693	608766	NP_061027	NM_018557	ENSP00000374135	candidate	0	0	0	Eukaryotes	19	2	Cellular processes	24	chr2	140990758	142888298	HTMS,WES	lung,chronic lymphocytic leukemia,gastric,kidney
4036	LRP2	low density lipoprotein receptor-related protein 2	2q24-q31	02509	6694	600073	NP_004516	NM_004525	ENSP00000263816	candidate	0	0	0	Eukaryotes	60	0	Cellular metabolism,Cellular processes,Development	34	chr2	169985176	170218909	WES	bladder,glioblastoma
4041	LRP5	low density lipoprotein receptor-related protein 5	11q13.4	04616	6697	603506	NP_002326	NM_002335	ENSP00000294304	candidate	0	0	0	Last Universal Common Ancestor	2	1	Cell cycle,Cell motility and interactions,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction	19	chr11	68115314	68216535	WGS	lymphoma
339291	LRRC30	leucine rich repeat containing 30	18p11.23	-	30219	-	NP_001099051	NM_001105581	ENSP00000372959	candidate	0	0	0	Last Universal Common Ancestor	0	0	-1	-1	chr18	7231137	7232039	WGS	liver
10489	LRRC41	leucine rich repeat containing 41	1p34.1	10102	16917	-	NP_006360	NM_006369	ENSP00000343298	candidate	0	0	0	Metazoans	8	1	-1	68	chr1	46744540	46768994	WGS	prostate
23639	LRRC6	leucine rich repeat containing 6	8q24.22	10286	16725	-	NP_036604	NM_012472	ENSP00000250173	candidate	0	0	0	Eukaryotes	32	0	-1	20	chr8	133584557	133673871	WGS	lymphoma
57554	LRRC7	leucine rich repeat containing 7	1p31.1	09930	18531	614453	NP_065845	NM_020794	ENSP00000035383	candidate	0	0	0	Last Universal Common Ancestor	12	0	-1	-1	chr1	70225888	70587567	WES	breast,glioblastoma
80131	LRRC8E	leucine rich repeat containing 8 family, member E	19p13.2	08670	26272	612891	NP_079337	NM_025061	ENSP00000306524	candidate	0	0	0	Last Universal Common Ancestor	15	1	-1	29	chr19	7960489	7965795	WGS	lung
9208	LRRFIP1	leucine rich repeat (in FLII) interacting protein 1	2q37.3	04460	6702	603256	NP_004726;NP_001131024;NP_001131022;NP_001131025;NP_001131023	NM_004735;NM_001137552;NM_001137550;NM_001137553;NM_001137551	ENSP00000289175;ENSP00000244815	candidate	0	0	1	Metazoans	10	5	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	109	chr2	238601099	238672780	WES,WGS	breast,melanoma
127255	LRRIQ3	leucine-rich repeats and IQ motif containing 3	1p31.1	14485	28318	-	NP_001099129	NM_001105659;NM_145258	ENSP00000346414	candidate	0	0	0	Eukaryotes	0	0	-1	-1	chr1	74492500	74649368	WES	lymphoma
79705	LRRK1	leucine-rich repeat kinase 1	15q26.3	14319	18608	610986	NP_078928	NM_024652	ENSP00000373600	candidate	0	0	0	Last Universal Common Ancestor	34	0	Cellular metabolism,Cellular processes,Signal transduction	24	chr15	101464838	101609050	WGS	melanoma
120892	LRRK2	leucine-rich repeat kinase 2	12q12	-	18618	609007	NP_940980	NM_198578	ENSP00000298910	candidate	0	0	0	Last Universal Common Ancestor	149	2	Cell cycle,Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction	-1	chr12	40618934	40761564	WES,WGS	kidney,lung
54674	LRRN3	leucine rich repeat neuronal 3	7q31.1	14321	17200	-	NP_001093128;NP_060804;NP_001093130	NM_001099658;NM_018334;NM_001099660	ENSP00000312001;ENSP00000397312;ENSP00000412417	candidate	0	0	0	Last Universal Common Ancestor	0	2	-1	78	chr7	110762829	110764952	WES	pancreas
347730	LRRTM1	leucine rich repeat transmembrane neuronal 1	2p12	14323	19408	610867	NP_849161	NM_178839	ENSP00000295057	candidate	0	0	0	Last Universal Common Ancestor	0	3	-1	-1	chr2	80529379	80530944	WES	head and neck squamous cell carcinoma
347731	LRRTM3	leucine rich repeat transmembrane neuronal 3	10q21.3	14324	19410	610869	NP_821079	NM_178011	-	candidate	0	0	0	Last Universal Common Ancestor	0	0	-1	-1	chr10	68686678	68857551	WGS	glioblastoma
80059	LRRTM4	leucine rich repeat transmembrane neuronal 4	2p12	11288	19411	610870	NP_079269;NP_001128217	NM_024993;NM_001134745	ENSP00000386236	candidate	0	0	0	Last Universal Common Ancestor	0	0	-1	22	chr2	77745444	77746991	WES	pancreas
27257	LSM1	LSM1 homolog, U6 small nuclear RNA associated (S. cerevisiae)	8p11.2	06281	20472	607281	NP_055277	NR_045493;NM_014462;NR_045492	ENSP00000310596	known	0	0	0	Eukaryotes	18	2	DNA/RNA metabolism and transcription,Regulation of transcription	79	chr8	38021191	38033838	CGC,Amplified	
4048	LTA4H	leukotriene A4 hydrolase	12q22	01056	6710	151570	NP_000886	NM_000895	ENSP00000228740;ENSP00000449958;ENSP00000395051	candidate	0	0	0	Last Universal Common Ancestor	16	4	Cellular metabolism,Immune system response	106	chr12	96394770	96429297	WGS	acute myeloid leukemia
4053	LTBP2	latent transforming growth factor beta binding protein 2	14q24	03650	6715	602091	NP_000419	NM_000428	ENSP00000261978	candidate	0	0	0	Eukaryotes	3	1	Cellular processes,Signal transduction	88	chr14	74967590	75078647	WGS	liver
4058	LTK	leukocyte receptor tyrosine kinase	15q15.1-q21.1	01052	6721	151520	NP_002335;NP_996844;NP_001129157	NM_002344;NM_206961;NM_001135685	ENSP00000392196;ENSP00000263800;ENSP00000347293	candidate	0	0	0	Last Universal Common Ancestor	11	1	Cellular metabolism,Cellular processes,Signal transduction	24	chr15	41796197	41805907	HTMS	lung,sarcoma
338645	LUZP2	leucine zipper protein 2	11p14.3	17348	23206	608178	NP_001009909;NP_001238937;NP_001238939	NM_001009909;NM_001252008;NM_001252010	ENSP00000432952	candidate	0	0	0	Vertebrates	2	0	-1	31	chr11	24518790	25100201	WES	chronic lymphocytic leukemia
129530	LYG1	lysozyme G-like 1	2q11.2	14043	27014	-	NP_777558	NM_174898	ENSP00000311320	candidate	0	0	0	Mammals	0	0	Cellular metabolism,Cellular processes	-1	chr2	99900859	99909110	WGS	lymphoma
4066	LYL1	lymphoblastic leukemia derived sequence 1	19p13.2	01046	6734	151440	NP_005574	NM_005583	ENSP00000264824	known	1	0	0	Vertebrates	9	1	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	28	chr19	13210136	13211985	CGC	leukemia
84328	LZIC	leucine zipper and CTNNBIP1 domain containing	1p36.22	14340	17497	610458	NP_115744	NM_032368	ENSP00000383695	candidate	0	0	0	Eukaryotes	3	3	-1	-1	chr1	9990460	9996677	WGS	glioblastoma
23499	MACF1	microtubule-actin crosslinking factor 1	1p32-p31	09750	13664	608271	NP_036222;NP_149033	NM_012090;NM_033044	ENSP00000439537	candidate	0	0	0	Eukaryotes	13	5	Cell cycle	108	chr1	39549891	39951463	WES	pancreas
8567	MADD	MAP-kinase activating death domain	11p11.2	04664	6766	603584	NP_569832;NP_001129415;NP_001129416;NP_569827;NP_003673;NP_569828;NP_569826;NP_569831;NP_569830;NP_569829	NM_130476;NM_001135943;NM_001135944;NM_130471;NM_003682;NM_130472;NM_130470;NM_130475;NM_130474;NM_130473	ENSP00000378753;ENSP00000310933;ENSP00000343902;ENSP00000384204;ENSP00000385585;ENSP00000304505;ENSP00000384435;ENSP00000378745;ENSP00000384287	candidate	0	0	0	Last Universal Common Ancestor	13	1	Cell cycle,Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction	95	chr11	47295466	47350698	WGS	melanoma
4094	MAF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)	16q22-q23	01518	6776	177075	NP_001026974;NP_005351	NM_001031804;NM_005360	ENSP00000377019;ENSP00000327048	known	1	0	0	Metazoans	21	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	82	chr16	79628360	79633799	CGC	myeloma
389692	MAFA	v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)	8q24.3	14346	23145	610303	NP_963883	NM_201589	ENSP00000328364	candidate	0	0	0	Metazoans	10	0	Cell response to stimuli,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	-1	chr8	144511518	144512576	WES	head and neck squamous cell carcinoma
9935	MAFB	v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)	20q11.2-q13.1	07129	6408	608968	NP_005452	NM_005461	ENSP00000362410	known	1	0	0	Metazoans	10	4	Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription	55	chr20	39316522	39317490	CGC	myeloma
4099	MAG	myelin associated glycoprotein	19q13.1	01160	6783	159460	NP_002352;NP_542167;NP_001186145	NM_002361;NM_080600;NM_001199216	ENSP00000440695;ENSP00000376048;ENSP00000355234	candidate	0	0	0	Last Universal Common Ancestor	1	0	-1	36	chr19	35786312	35804354	HTMS	breast,lung,ovarian,pancreas,prostate
4105	MAGEA6	melanoma antigen family A, 6	Xq28	02168	6804	300176	NP_787064;NP_005354	NM_175868;NM_005363	ENSP00000329199	candidate	0	0	6	Eukaryotes	38	2	-1	1	chrX	151869311	151870252	WES	pancreas
9947	MAGEC1	melanoma antigen family C, 1	Xq26	02201	6812	300223	NP_005453	NM_005462	ENSP00000285879	candidate	0	0	0	Eukaryotes	36	0	-1	32	chrX	140993194	140996616	WES	head and neck squamous cell carcinoma
51438	MAGEC2	melanoma antigen family C, 2	Xq27	06632	13574	300468	NP_057333;XP_003403911	NM_016249;XM_003403863	ENSP00000354660	candidate	0	0	1	Eukaryotes	7	0	-1	41	chrX	141290655	141291773	WES	head and neck squamous cell carcinoma
139081	MAGEC3	melanoma antigen family C, 3	Xq27.2	06629	23798	300469	NP_619647;NP_803251	NM_138702;NM_177456	ENSP00000298296;ENSP00000440444	candidate	0	0	0	Eukaryotes	0	1	-1	16	chrX	140926102	140985615	WES	lymphoma
9500	MAGED1	melanoma antigen family D, 1	Xp11.23	02202	6813	300224	NP_001005333;NP_008917;NP_001005332	NM_001005333;NM_006986;NM_001005332	ENSP00000364927;ENSP00000364847;ENSP00000325333	candidate	0	0	0	Eukaryotes	109	0	Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	105	chrX	51637401	51645023	WES,WGS	myeloma
57692	MAGEE1	melanoma antigen family E, 1	Xq13.3	06583	24934	300759	NP_065983	NM_020932	ENSP00000354912	candidate	0	0	0	Last Universal Common Ancestor	8	0	-1	-1	chrX	75648324	75651194	WES,WGS	breast,chronic lymphocytic leukemia
378938	MALAT1	metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)	11q13.1	-	29665	607924	-	NR_002819	-	known	1	0	-1	Primates	0	0	-1	-1	-	0	0	CGC	kidney
10892	MALT1	mucosa associated lymphoid tissue lymphoma translocation gene 1	18q21	06892	6819	604860	NP_776216;NP_006776	NM_173844;NM_006785	ENSP00000319279	known	1	0	0	Last Universal Common Ancestor	21	1	Cell cycle,Cell response to stimuli,Cellular metabolism,Cellular processes,Development,Immune system response,Regulation of intracellular processes and metabolism,Signal transduction	50	chr18	56338876	56415071	CGC	lymphoma
158056	MAMDC4	MAM domain containing 4	9q34.3	12434	24083	-	NP_996803	NM_206920	ENSP00000319388	candidate	0	0	0	Eukaryotes	0	0	Cellular processes	-1	chr9	139746869	139755052	WES	breast
84441	MAML2	mastermind-like 2 (Drosophila)	11q21	09608	16259	607537	NP_115803	NM_032427	ENSP00000412394	known	1	0	0	Metazoans	8	1	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	-1	chr11	95712115	96075059	CGC	salivary
4131	MAP1B	microtubule-associated protein 1B	5q13	01139	6836	157129	NP_005900	NM_032010;NM_005909	ENSP00000296755	candidate	0	0	0	Last Universal Common Ancestor	23	8	Cell cycle,Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism	94	chr5	71403359	71501063	WES	colorectal
4133	MAP2	microtubule-associated protein 2	2q34-q35	01140	6839	157130	NP_002365;NP_114035;NP_001034627;NP_114033	NM_002374;NM_031846;NM_031847;NM_001039538;NM_031845	ENSP00000353508;ENSP00000376032	candidate	0	0	0	Last Universal Common Ancestor	7	1	Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism	43	chr2	210517895	210595118	WES	colorectal
6416	MAP2K4	mitogen-activated protein kinase kinase 4	17p11.2	03213	6844	601335	NP_003001	NM_003010	ENSP00000262445	known	0	1	1	Last Universal Common Ancestor	47	2	Cellular metabolism,Cellular processes,Signal transduction	83	chr17	11924204	12044574	CGC,WES	breast,colorectal,pancreas
5609	MAP2K7	mitogen-activated protein kinase kinase 7	19p13.3-p13.2	-	6847	603014	NP_660186	NM_145185	ENSP00000381066	candidate	0	0	0	Last Universal Common Ancestor	10	0	Cellular metabolism,Cellular processes,Signal transduction	59	chr19	7968830	7977313	WES	colorectal
4214	MAP3K1	mitogen-activated protein kinase kinase kinase 1	5q11.2	-	6848	600982	NP_005912	NM_005921	ENSP00000382423	candidate	0	0	0	Last Universal Common Ancestor	166	2	Cellular metabolism,Cellular processes,Signal transduction	9	chr5	56111401	56189504	HTMS,WES	breast,lung,ovarian,pancreas,prostate
9175	MAP3K13	mitogen-activated protein kinase kinase kinase 13	3q27	05372	6852	604915	NP_001229246;NP_004712;NP_001229243	NM_001242317;NM_004721;NR_038322;NM_001242314	ENSP00000265026	candidate	0	0	0	Last Universal Common Ancestor	7	0	Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	6	chr3	185146370	185200241	WES	breast
4216	MAP3K4	mitogen-activated protein kinase kinase kinase 4	6q26	03886	6856	602425	NP_005913;NP_006715	NM_005922;NM_006724	ENSP00000375986;ENSP00000355886	candidate	0	0	0	Last Universal Common Ancestor	27	3	Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction	64	chr6	161412964	161536337	WES	endometrium
4217	MAP3K5	mitogen-activated protein kinase kinase kinase 5	6q22.33	03904	6857	602448	NP_005914	NM_005923	ENSP00000351908	known	0	0	0	Last Universal Common Ancestor	114	0	Cell cycle,Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction	95	chr6	136878899	137113295	CGC,Amplified	
1326	MAP3K8	mitogen-activated protein kinase kinase kinase 8	10p11.23	01863	6860	191195	NP_001231063;NP_005195	NM_001244134;NM_005204	ENSP00000364470;ENSP00000263056	candidate	0	0	0	Last Universal Common Ancestor	40	7	Cellular metabolism,Cellular processes	24	chr10	30727868	30749762	WGS	breast
9448	MAP4K4	mitogen-activated protein kinase kinase kinase kinase 4	2q11.2-q12	05235	6866	604666	NP_663720;NP_001229488;NP_663719;NP_001229489;NP_004825	NM_145687;NM_001242559;NM_145686;NM_001242560;NM_004834	-	candidate	0	0	0	Last Universal Common Ancestor	42	0	Cellular metabolism,Cellular processes,Signal transduction	84	chr2	102314543	102507708	WGS	prostate
9053	MAP7	microtubule-associated protein 7	6q23.3	04982	6869	604108	NP_001185537;NP_001185548;NP_001185540;NP_001185545;NP_001185547;NP_001185538;NP_003971;NP_001185543;NP_001185544;NP_001185546	NM_001198608;NM_001198619;NM_001198611;NM_001198616;NM_001198618;NM_001198609;NM_003980;NM_001198614;NM_001198615;NM_001198617	ENSP00000346581	candidate	0	0	0	Metazoans	11	7	Cellular processes,Development	68	chr6	136666995	136847102	WES	colorectal (hypermutated)
23542	MAPK8IP2	mitogen-activated protein kinase 8 interacting protein 2	22q13.33	09674	6883	607755	NP_057515;NP_036456	NM_139124;NM_016431;NM_012324	ENSP00000330572	candidate	0	0	0	Metazoans	59	0	Cell cycle,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction	65	chr22	51039248	51049204	WES	colorectal
23162	MAPK8IP3	mitogen-activated protein kinase 8 interacting protein 3	16p13.3	12014	6884	605431	NP_001035529;NP_055948	NM_001040439;NM_015133	ENSP00000250894	candidate	0	0	0	Metazoans	43	0	Cellular processes,Signal transduction	71	chr16	1756341	1818822	HTMS	breast,lung,ovarian,pancreas,prostate
23005	MAPKBP1	mitogen-activated protein kinase binding protein 1	15q15.1	17465	29536	-	NP_055809;NP_001122080	NM_014994;NM_001128608	ENSP00000393099;ENSP00000426154;ENSP00000397570	candidate	0	0	0	Last Universal Common Ancestor	4	0	-1	27	chr15	42067474	42117631	WES	breast
116511	MAS1L	MAS1 oncogene-like	6p21	06251	13961	607235	NP_443199	NM_052967	ENSP00000366331	candidate	0	0	0	Mammals	0	3	Signal transduction	-1	chr6	29454546	29455679	HTMS	breast,lung,ovarian,pancreas,prostate
10747	MASP2	mannan-binding lectin serine peptidase 2	1p36.3-p36.2	05484	6902	605102	NP_006601;NP_631947	NM_006610;NM_139208	ENSP00000383690;ENSP00000383691	candidate	0	0	0	Last Universal Common Ancestor	11	0	Cell response to stimuli,Cellular metabolism,Immune system response	80	chr1	11086945	11107178	WGS	prostate
4155	MBP	myelin basic protein	18q23	01158	6925	159430	NP_001020271;NP_001020261;NP_001020272;NP_002376;NP_001020263;NP_001020252	NM_001025100;NM_001025090;NM_001025101;NM_001025098;NM_001025094;NM_002385;NM_001025092;NM_001025081	ENSP00000372025;ENSP00000380964;ENSP00000380963;ENSP00000380958;ENSP00000348273	candidate	0	0	0	Last Universal Common Ancestor	8	0	Development,Multicellular activities,Regulation of intracellular processes and metabolism	94	chr18	74696731	74817217	WGS	chronic lymphocytic leukemia
4159	MC3R	melanocortin 3 receptor	20q13.2-q13.3	01115	6931	155540	NP_063941	NM_019888	ENSP00000243911	candidate	0	0	0	Metazoans	5	0	Signal transduction	42	chr20	54823900	54824868	HTMS	breast,lung,ovarian,pancreas,prostate
4162	MCAM	melanoma cell adhesion molecule	11q23.3	01120	6934	155735	NP_006491	NM_006500	ENSP00000264036	candidate	0	0	0	Eukaryotes	8	8	-1	100	chr11	119181059	119187811	WES	acute myeloid leukemia
90411	MCFD2	multiple coagulation factor deficiency 2	2p21	09693	18451	607788	NP_644808;NP_001164979;NP_001164978;NP_001164981;NP_001164982;NP_001164980;NP_001164977	NM_139279;NM_001171508;NM_001171507;NM_001171510;NM_001171511;NM_001171509;NM_001171506	ENSP00000386941;ENSP00000387202;ENSP00000394647;ENSP00000317271	candidate	0	0	0	Metazoans	9	2	Cellular metabolism,Cellular processes	90	chr2	47132605	47136310	WGS	chronic lymphocytic leukemia
2847	MCHR1	melanin-concentrating hormone receptor 1	22q13.2	11874	4479	601751	NP_005288	NM_005297	ENSP00000249016	candidate	0	0	0	Metazoans	0	0	Regulation of intracellular processes and metabolism,Signal transduction	36	chr22	41075450	41077929	WES	gastric
84539	MCHR2	melanin-concentrating hormone receptor 2	6q16	12088	20867	606111	NP_115892;NP_001035269	NM_032503;NM_001040179	ENSP00000281806;ENSP00000403490	candidate	0	0	0	Vertebrates	1	1	Signal transduction	-1	chr6	100368819	100404023	HTMS	breast,lung,ovarian,pancreas,prostate
8888	MCM3AP	minichromosome maintenance complex component 3 associated protein	21q22.3	04483	6946	603294	NP_003897	NM_003906	ENSP00000291688	candidate	0	0	0	Eukaryotes	35	0	Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription	86	chr21	47655185	47705200	WES	colorectal
79892	MCMBP	minichromosome maintenance complex binding protein	10q26.11	07624	25782	610909	NP_001243308;NP_001243307;NP_079110	NM_001256379;NM_001256378;NM_024834	ENSP00000353098	candidate	0	0	0	Eukaryotes	19	3	-1	62	chr10	121590989	121632096	WES	melanoma
161357	MDGA2	MAM domain containing glycosylphosphatidylinositol anchor 2	14q21.3	14352	19835	611128	NP_001106970;NP_878250	NM_001113498;NM_182830	ENSP00000382178;ENSP00000405456	candidate	0	0	0	Last Universal Common Ancestor	0	1	Cell cycle,Development	-1	chr14	47311137	48143999	WGS	chronic lymphocytic leukemia
4193	MDM2	Mdm2 p53 binding protein homolog (mouse)	12q14.3-q15	01272	6973	164785	NP_002383	NM_032739;NM_006882;NM_001145340;NM_006878;NM_001145337;NM_006880;NM_006881;NM_001145339;NM_006879;NM_002392;NM_001145336	ENSP00000417281	known	1	0	0	Eukaryotes	405	7	Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	27	chr12	69202986	69233626	CGC,WES,Amplified	colorectal,glioma,other,sarcoma,lung
4194	MDM4	Mdm4 p53 binding protein homolog (mouse)	1q32	04082	6974	602704	NP_001191100;NP_002384;NP_001191101	NM_001204171;NR_024171;NM_002393;NM_001204172	ENSP00000356150	known	1	0	0	Eukaryotes	75	7	Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	8	chr1	204494647	204518807	CGC,Amplified	bladder,glioblastoma,retinoblastoma
145553	MDP1	magnesium-dependent phosphatase 1	14q12	14695	28781	-	NP_612485;NP_001186751;NP_001186750	NM_138476;NM_001199822;NM_001199821	ENSP00000380045;ENSP00000288087	candidate	0	0	0	Last Universal Common Ancestor	2	0	-1	-1	chr14	24683233	24685004	WGS	glioblastoma
259283	MDS2	myelodysplastic syndrome 2 translocation associated	1p36	-	29633	607305	-	NR_027042	-	known	1	0	-1	Primates	0	0	-1	-1	-	0	0	CGC	myelodysplasia
2122	MECOM	MDS1 and EVI1 complex locus	3q26	01310	3498	165215	NP_005232;NP_001098548;NP_004982;NP_001157471;NP_001098547;NP_001192123;NP_001157472	NM_005241;NM_001105078;NM_004991;NM_001163999;NM_001105077;NM_001205194;NM_001164000	ENSP00000264674;ENSP00000419770;ENSP00000376493	known	1	0	0	Last Universal Common Ancestor	21	0	-1	41	chr3	168802700	169099322	CGC	leukemia,myelodysplasia
5469	MED1	mediator complex subunit 1	17q12	05055	9234	604311	NP_004765	NM_004774	-	candidate	0	0	0	Last Universal Common Ancestor	110	2	Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	69	chr17	37563731	37604158	WES	head and neck squamous cell carcinoma
9968	MED12	mediator complex subunit 12	Xq13	02176	11957	300188	NP_005111	NM_005120	ENSP00000363193	known	1	0	0	Eukaryotes	63	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	91	chrX	70338605	70362065	CGC,WES	uterus,prostate
116931	MED12L	mediator complex subunit 12-like	3q25.1	10278	16050	611318	NP_443728	NM_053002	ENSP00000417235	candidate	0	0	0	Eukaryotes	18	1	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	-1	chr3	150804714	151150589	WES	lymphoma
55588	MED29	mediator complex subunit 29	19q13.2	13748	23074	612914	NP_060062	NM_017592	ENSP00000314343	known	0	0	0	Metazoans	110	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	-1	chr19	39882000	39888336	CGC,Amplified	
100271849	MEF2B	myocyte enhancer factor 2B	19p13.11	-	6995	600661	NP_001139257	NM_001145785	ENSP00000402154	candidate	0	0	0	Eukaryotes	6	0	-1	-1	chr19	19256609	19261544	WES	lymphoma,non-hodgkin lymphoma
4208	MEF2C	myocyte enhancer factor 2C	5q14	02809	6996	600662	NP_002388;NP_001180276;NP_001124477;NP_001180279;NP_001180278;NP_001180277	NM_002397;NM_001193347;NM_001131005;NM_001193350;NM_001193349;NM_001193348	ENSP00000389610;ENSP00000340874;ENSP00000421925	candidate	0	0	0	Eukaryotes	44	3	Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription	83	chr5	88018424	88119605	WES	head and neck squamous cell carcinoma,lymphoma
150365	MEI1	meiosis inhibitor 1	22q13.2	-	28613	608797	NP_689726	NM_152513	ENSP00000384115	candidate	0	0	0	Metazoans	1	0	-1	-1	chr22	42095543	42195300	WGS	melanoma
4221	MEN1	multiple endocrine neoplasia I	11q13	00564	7010	613733	NP_570713;NP_570714;NP_570715;NP_000235;NP_570716;NP_570712;NP_570711	NM_130801;NM_130802;NM_130803;NM_000244;NM_130804;NM_130800;NM_130799	ENSP00000396940;ENSP00000308975;ENSP00000366538;ENSP00000377899;ENSP00000337088;ENSP00000377901	known	0	1	0	Eukaryotes	18	0	Cell cycle,Cell response to stimuli,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	102	chr11	64571809	64577581	CGC,WES	pancreas,thyroid
4224	MEP1A	meprin A, alpha (PABA peptide hydrolase)	6p12-p11	02666	7015	600388	NP_005579	NM_005588	ENSP00000230588	candidate	0	0	0	Eukaryotes	21	1	Cellular metabolism	4	chr6	46761136	46806870	WES	pancreas
56955	MEPE	matrix extracellular phosphoglycoprotein	4q21.1	06908	13361	605912	NP_001171624;NP_064588;NP_001171625;NP_001171626;NP_001171623	NM_001184695;NM_020203;NM_001184696;NM_001184697;NM_001184694	ENSP00000416984;ENSP00000443491;ENSP00000453994;ENSP00000354341	candidate	0	0	0	Mammals	9	4	Development	7	chr4	88755867	88767595	WGS	lung
4233	MET	met proto-oncogene (hepatocyte growth factor receptor)	7q31	01280	7029	164860	NP_000236;NP_001120972	NM_000245;NM_001127500	ENSP00000380860	known	1	0	0	Last Universal Common Ancestor	76	17	Cell cycle,Cell motility and interactions,Cellular metabolism,Cellular processes,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction	85	chr7	116339139	116436175	CGC,Amplified	head and neck squamous cell carcinoma,kidney
10988	METAP2	methionyl aminopeptidase 2	12q22	03522	16672	601870	NP_006829	NM_006838	ENSP00000325312	candidate	0	0	0	Last Universal Common Ancestor	0	8	Cellular metabolism,Cellular processes	81	chr12	95867956	95907677	WGS	prostate
64745	METTL17	methyltransferase like 17	14q11.2	13379	19280	-	NP_073571;NP_001025162	NM_022734;NM_001029991;NM_001029992	ENSP00000372445;ENSP00000343041	candidate	0	0	0	Last Universal Common Ancestor	11	0	-1	33	chr14	21458162	21465039	WGS	prostate
56339	METTL3	methyltransferase like 3	14q11.1	14389	17563	612472	NP_062826	NM_019852	ENSP00000298717	candidate	0	0	0	Last Universal Common Ancestor	3	0	Cellular metabolism,DNA/RNA metabolism and transcription	98	chr14	21966405	21979365	WES	gastric
256471	MFSD8	major facilitator superfamily domain containing 8	4q28.2	14557	28486	611124	NP_689991	NM_152778	ENSP00000296468	candidate	0	0	0	Eukaryotes	0	0	-1	-1	chr4	128841788	128886288	WGS	liver
23269	MGA	MAX gene associated	15q14	-	14010	-	NP_001157745;NP_001074010	NM_001164273;NM_001080541	ENSP00000442467;ENSP00000219905	candidate	0	0	0	Last Universal Common Ancestor	6	2	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	6	chr15	41961093	42059475	WGS	chronic lymphocytic leukemia
8972	MGAM	maltase-glucoamylase (alpha-glucosidase)	7q34	01104	7043	154360	NP_004659	NM_004668	ENSP00000447378	candidate	0	0	0	Last Universal Common Ancestor	14	0	Cellular metabolism	4	chr7	141705331	141805688	WGS	prostate
57553	MICAL3	microtubule associated monoxygenase, calponin and LIM domain containing 3	22q11.21	-	24694	608882	NP_001116203;NP_001129476;NP_056056	NM_001122731;NM_001136004;NM_015241	ENSP00000410315;ENSP00000414846;ENSP00000416015	candidate	0	0	0	Eukaryotes	2	0	-1	34	chr22	18273501	18389578	WGS	glioblastoma
166968	MIER3	mesoderm induction early response 1, family member 3	5q11.2	08199	26678	-	NP_689835	NM_152622	ENSP00000370611	candidate	0	0	0	Eukaryotes	1	9	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	-1	chr5	56218958	56242902	WES	colorectal (hypermutated)
4286	MITF	microphthalmia-associated transcription factor	3p14.2-p14.1	01138	7105	156845	NP_000239;NP_937802;NP_937821;NP_001171897;NP_006713;NP_001171896;NP_937801;NP_937820	NM_000248;NM_198159;NM_198178;NM_001184968;NM_006722;NM_001184967;NM_198158;NM_198177	ENSP00000377884;ENSP00000327867;ENSP00000295600	known	1	0	0	Opisthokonts	4	5	Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription	69	chr3	69788749	70014396	CGC,Amplified	melanoma
57591	MKL1	megakaryoblastic leukemia (translocation) 1	22q13	10445	14334	606078	NP_065882	NM_020831	ENSP00000347847	known	1	0	0	Opisthokonts	64	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	83	chr22	40807397	40831556	CGC	leukemia
7681	MKRN3	makorin ring finger protein 3	15q11-q13	04836	7114	603856	NP_005655	NM_005664	ENSP00000313881	candidate	0	0	0	Eukaryotes	49	0	-1	7	chr15	23810930	23812450	HTMS,WES	breast,lung,ovarian,pancreas,prostate,colorectal
4291	MLF1	myeloid leukemia factor 1	3q25.1	03239	7125	601402	NP_001182361;NP_001123628;NP_001182362;NP_071888;NP_001182363;NP_001123629	NM_001195432;NM_001130156;NM_001195433;NM_022443;NM_001195434;NM_001130157	ENSP00000352025;ENSP00000348157	known	1	0	0	Eukaryotes	11	0	Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development	62	chr3	158310221	158322988	CGC	leukemia
4292	MLH1	mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)	3p21.3	00390	7127	120436	NP_001161091;NP_001161089;NP_001161090;NP_000240	NM_001167619;NM_001167617;NM_001167618;NM_000249	ENSP00000231790;ENSP00000402564;ENSP00000398272;ENSP00000443665;ENSP00000416687;ENSP00000402667	known	0	1	0	Last Universal Common Ancestor	145	3	Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism	107	chr3	37035039	37092141	CGC	central nervous system,colorectal,endometrium,ovarian
4297	MLL	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)	11q23	01162	7132	159555	NP_001184033;NP_005924	NM_024891;NM_001197104;NM_005933	ENSP00000436786;ENSP00000374157	known	1	0	0	Last Universal Common Ancestor	99	5	Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription	93	chr11	118307228	118392884	CGC,WES,WGS	leukemia,bladder,medulloblastoma,prostate,liver
8085	MLL2	myeloid/lymphoid or mixed-lineage leukemia 2	12q13.12	03664	7133	602113	NP_003473	NM_003482	ENSP00000301067	known	0	1	0	Last Universal Common Ancestor	60	7	Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription	23	chr12	49415566	49449107	CGC,HTMS,WES,WGS	kidney,medulloblastoma,breast,head and neck squamous cell carcinoma,lung,lymphoma,non-hodgkin lymphoma,prostate
58508	MLL3	myeloid/lymphoid or mixed-lineage leukemia 3	7q36.1	06016	13726	606833	NP_733751	NM_021230;NM_170606	ENSP00000262189	known	0	1	0	Last Universal Common Ancestor	27	4	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	-1	chr7	151833920	152132871	CGC,WES,WGS	medulloblastoma,bladder,breast,cholangiocarcinoma,pancreas,prostate,liver
4298	MLLT1	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1	19p13.3	15933	7134	159556	NP_005925	NM_005934	-	known	1	0	0	Last Universal Common Ancestor	32	3	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	0	chr19	6213056	6270773	CGC	leukemia
8028	MLLT10	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10	10p12	03874	16063	602409	NP_001182557;NP_004632;NP_001182559;NP_001182556;NP_001182555	NM_001009569;NM_001195628;NM_004641;NM_001195630;NM_001195627;NM_001195626	ENSP00000307411;ENSP00000366304;ENSP00000366272	known	1	0	0	Eukaryotes	14	1	-1	88	chr10	21823574	22030909	CGC	leukemia
10962	MLLT11	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11	1q21	05251	16997	604684	NP_006809	NM_006818	-	known	1	0	0	Vertebrates	0	4	-1	91	chr1	151039701	151039970	CGC	leukemia
4300	MLLT3	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3	9p22	01163	7136	159558	NP_004520	NM_004529	-	known	1	0	0	Last Universal Common Ancestor	45	3	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	63	chr9	20346444	20620833	CGC	leukemia
4301	MLLT4	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4	6q27	01164	7137	159559	NP_001035089;NP_001193937	NM_001040000;NM_001207008;NM_001040001;NM_005936	ENSP00000375956;ENSP00000375960	known	1	0	0	Eukaryotes	73	4	Signal transduction	20	chr6	168227813	168370612	CGC	leukemia
4302	MLLT6	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6	17q21	08978	7138	600328	NP_005928	NM_005937	ENSP00000316426	known	1	0	0	Eukaryotes	14	5	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	-1	chr17	36861886	36881848	CGC,HTMS	leukemia,breast,lung,ovarian,pancreas,prostate
4320	MMP11	matrix metallopeptidase 11 (stromelysin 3)	22q11.2|22q11.23	01705	7157	185261	NP_005931	NM_005940	ENSP00000215743	candidate	0	0	0	Eukaryotes	2	1	Cellular metabolism	47	chr22	24115058	24125728	WGS	melanoma
4313	MMP2	matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)	16q13-q21	00386	7166	120360	NP_004521;NP_001121363	NM_004530;NM_001127891	ENSP00000219070	candidate	0	0	0	Eukaryotes	45	5	Cellular metabolism,Development	96	chr16	55513392	55539351	WES	colorectal
4330	MN1	meningioma (disrupted in balanced translocation) 1	22q11|22q12.1	08862	7180	156100	NP_002421	NM_002430	ENSP00000304956	known	1	0	0	Metazoans	1	4	Cell cycle,Regulation of intracellular processes and metabolism	66	chr22	28146906	28196531	CGC	leukemia,meningioma
4331	MNAT1	menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis)	14q23	04042	7181	602659	NP_002422;NP_001171434	NM_002431;NM_001177963	ENSP00000446437	candidate	0	0	0	Eukaryotes	84	1	Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	5	chr14	61201581	61435064	HTMS	breast,lung,ovarian,pancreas,prostate
3110	MNX1	motor neuron and pancreas homeobox 1	7q36	00874	4979	142994	NP_001158727;NP_005506	NM_001165255;NM_005515	ENSP00000438552;ENSP00000252971	known	1	0	0	Metazoans	0	2	Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription	17	chr7	156798217	156803044	CGC	leukemia
79817	MOB3B	MOB kinase activator 3B	9p21.2	14728	23825	-	NP_079037	NM_024761	ENSP00000262244	candidate	0	0	2	Eukaryotes	9	6	-1	54	chr9	27359032	27455548	WGS	glioblastoma
4337	MOCS1	molybdenum cofactor synthesis 1	6p21.3	04749	7190	603707	NP_001068566;NP_005934	NM_005942;NR_033233;NM_138928;NM_001075098;NM_005943	ENSP00000362284;ENSP00000362282	candidate	0	0	1	Last Universal Common Ancestor	1	0	Cellular metabolism	51	chr6	39876826	39902156	WGS	liver
27136	MORC1	MORC family CW-type zinc finger 1	3q13	04439	7198	603205	NP_055244	NM_014429	ENSP00000232603	candidate	0	0	0	Last Universal Common Ancestor	1	0	Development,Multicellular activities	1	chr3	108677815	108836906	WGS	breast
4342	MOS	v-mos Moloney murine sarcoma viral oncogene homolog	8q11	01816	7199	190060	NP_005363	NM_005372	ENSP00000310722	candidate	0	0	0	Last Universal Common Ancestor	6	0	Cellular metabolism,Cellular processes	58	chr8	57025504	57026541	HTMS	sarcoma
4352	MPL	myeloproliferative leukemia virus oncogene	1p34	01161	7217	159530	NP_005364	NM_005373	-	known	1	0	0	Vertebrates	11	0	Signal transduction	19	chr1	43803520	43818440	CGC	myeloma
744	MPPED2	metallophosphoesterase domain containing 2	11p13	02947	1180	600911	NP_001575;NP_001138871	NM_001584;NM_001145399	ENSP00000388258;ENSP00000350833	candidate	0	0	1	Last Universal Common Ancestor	1	1	Development	48	chr11	30433018	30601920	WGS	melanoma
4361	MRE11A	MRE11 meiotic recombination 11 homolog A (S. cerevisiae)	11q21	02889	7230	600814	NP_005581;NP_005582	NM_005590;NM_005591	-	candidate	0	0	1	Last Universal Common Ancestor	49	7	Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	14	chr11	94153294	94224130	WES	breast
29074	MRPL18	mitochondrial ribosomal protein L18	6q25.3	14744	14477	611831	NP_054880	NM_014161	ENSP00000356001	candidate	0	0	0	Eukaryotes	2	2	Cellular metabolism,Regulation of transcription	109	chr6	160211620	160219152	WGS	glioblastoma
4436	MSH2	mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)	2p21	00389	7325	609309	NP_000242	NM_000251	ENSP00000233146;ENSP00000442697	known	0	1	0	Last Universal Common Ancestor	19	8	Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism	45	chr2	47630331	47710085	CGC	colorectal,endometrium,ovarian
4437	MSH3	mutS homolog 3 (E. coli)	5q11-q12	02931	7326	600887	NP_002430	NM_002439	ENSP00000265081	candidate	0	0	0	Last Universal Common Ancestor	24	1	Cellular metabolism,DNA/RNA metabolism and transcription,Development,Immune system response	74	chr5	79950547	80171678	WES	colorectal (hypermutated)
2956	MSH6	mutS homolog 6 (E. coli)	2p16	07202	7329	600678	NP_000170	NM_000179	ENSP00000234420	known	0	1	0	Last Universal Common Ancestor	59	7	Cellular metabolism,DNA/RNA metabolism and transcription	76	chr2	48010373	48033996	CGC,WES	colorectal,colorectal (hypermutated)
124540	MSI2	musashi homolog 2 (Drosophila)	17q22	07438	18585	607897	NP_620412;NP_733839	NM_138962;NM_170721	ENSP00000313616	known	1	0	0	Last Universal Common Ancestor	7	1	-1	-1	chr17	55334104	55752487	CGC,HTMS	leukemia,breast,lung,ovarian,pancreas,prostate
4478	MSN	moesin	Xq11.1	02399	7373	309845	NP_002435	NM_002444	ENSP00000353408	known	1	0	2	Eukaryotes	63	2	Cell motility and interactions,Immune system response	106	chrX	64936680	64959752	CGC	lymphoma
4485	MST1	macrophage stimulating 1 (hepatocyte growth factor-like)	3p21	00798	7380	142408	NP_066278	NM_020998	ENSP00000414287	candidate	0	0	2	Last Universal Common Ancestor	6	1	Cellular metabolism,Multicellular activities	60	chr3	49721464	49726124	WGS	melanoma
4486	MST1R	macrophage stimulating 1 receptor (c-met-related tyrosine kinase)	3p21.3	02545	7381	600168	NP_002438;NP_001231866	NM_002447;NM_001244937	ENSP00000341325;ENSP00000296474	candidate	0	0	0	Last Universal Common Ancestor	32	0	Cell cycle,Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction	50	chr3	49924743	49941042	HTMS	sarcoma
9112	MTA1	metastasis associated 1	14q32.3	04633	7410	603526	NP_001190187;NP_004680	NM_001203258;NM_004689	ENSP00000333633	candidate	0	0	0	Metazoans	76	2	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	104	chr14	105905008	105936549	WGS	lung
9219	MTA2	metastasis associated 1 family, member 2	11q12-q13.1	07233	7411	603947	NP_004730	NM_004739	ENSP00000278823	candidate	0	0	0	Metazoans	76	5	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	10	chr11	62361350	62368162	WGS	lung
4515	MTCP1	mature T-cell proliferation 1	Xq28	02122	7423	300116	NP_001018025	NM_001018025;NM_014221	ENSP00000358488	known	1	0	0	Last Universal Common Ancestor	6	1	-1	21	chrX	154293768	154294285	CGC	leukemia
92140	MTDH	metadherin	8q22.1	17459	29608	610323	NP_848927	NM_178812	ENSP00000338235	known	0	0	0	Metazoans	15	8	-1	108	chr8	98656735	98736895	CGC,WGS,Amplified	liver
10903	MTMR11	myotubularin related protein 11	1q12-q21	16748	24307	-	NP_870988;NP_001139334	NM_181873;NM_006697;NM_001145862	ENSP00000391668;ENSP00000358136	candidate	0	0	0	Eukaryotes	1	0	-1	70	chr1	149901024	149908540	WGS	prostate
55613	MTMR8	myotubularin related protein 8	Xq11.2	06664	16825	-	NP_060147	NM_017677	ENSP00000363985	candidate	0	0	0	Eukaryotes	3	0	Cellular metabolism,Cellular processes	74	chrX	63488420	63579407	WES	lymphoma
23281	MTUS2	microtubule associated tumor suppressor candidate 2	13q12.3	11108	20595	-	NP_056048;NP_001028774	NM_015233;NM_001033602	-	candidate	0	0	0	Metazoans	35	4	-1	8	chr13	29598806	30077340	WES	breast,glioblastoma,pancreas
4582	MUC1	mucin 1, cell surface associated	1q21	01152	7508	158340	NP_002447;NP_001037857;NP_001018017;NP_001191216;NP_001191225;NP_001037858;NP_001191223;NP_001191220;NP_001191222;NP_001191224;NP_001191215;NP_001191226;NP_001191219;NP_001037855;NP_001191214;NP_001037856;NP_001191218;NP_001191217;NP_001018016;NP_001191221	NM_002456;NM_001018021;NM_001044392;NM_001018017;NM_001204287;NM_001204296;NM_182741;NM_001044393;NM_001204294;NM_001204291;NM_001204293;NM_001204295;NM_001204286;NM_001204297;NM_001204290;NM_001044390;NM_001204285;NM_001044391;NM_001204289;NM_001204288;NM_001018016;NM_001204292	ENSP00000357377;ENSP00000357380;ENSP00000343482;ENSP00000357378	known	1	0	0	Vertebrates	35	9	-1	91	chr1	155158614	155162634	CGC	non-hodgkin lymphoma
94025	MUC16	mucin 16, cell surface associated	19p13.2	-	15582	606154	NP_078966	NM_024690	ENSP00000381008	candidate	0	0	0	Last Universal Common Ancestor	3	0	-1	1	chr19	9056228	9091814	HTMS	breast,lung,ovarian,pancreas,prostate
140453	MUC17	mucin 17, cell surface associated	7q22.1	16335	16800	608424	NP_001035194	NM_001004430;NM_001040105	ENSP00000302716	candidate	0	0	0	Last Universal Common Ancestor	0	7	-1	-1	chr7	100663417	100699557	WGS	breast
4583	MUC2	mucin 2, oligomeric mucus/gel-forming	11p15.5	11828	7512	158370	NP_002448	NM_002457	ENSP00000415183	candidate	0	0	0	Last Universal Common Ancestor	7	0	Multicellular activities	28	chr11	1074902	1104260	WES	chronic lymphocytic leukemia
4585	MUC4	mucin 4, cell surface associated	3q29	11829	7514	158372	NP_612154;NP_004523;NP_060876	NM_138297;NM_138299;NM_138298;NM_004532;NM_018406	ENSP00000304207;ENSP00000417498;ENSP00000338109	candidate	0	0	0	Last Universal Common Ancestor	3	2	Cell motility and interactions	18	chr3	195474050	195518372	WGS	melanoma
727897	MUC5B	mucin 5B, oligomeric mucus/gel-forming	11p15.5	-	7516	600770	NP_002449	NM_002458	ENSP00000436812	candidate	0	0	0	Last Universal Common Ancestor	9	1	-1	3	chr11	1244354	1282835	WGS	liver
4595	MUTYH	mutY homolog (E. coli)	1p34.1	05380	7527	604933	NP_001041638;NP_001041636;NP_036354;NP_001041639;NP_001121897;NP_001041637	NM_001048173;NM_001048171;NM_012222;NM_001048174;NM_001128425;NM_001048172	ENSP00000361187;ENSP00000346354;ENSP00000347685;ENSP00000407590;ENSP00000408176;ENSP00000361170	known	0	1	0	Last Universal Common Ancestor	13	0	Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism	86	chr1	45794981	45800183	CGC	
4600	MX2	myxovirus (influenza virus) resistance 2 (mouse)	21q22.3	01001	7533	147890	NP_002454	NM_002463	ENSP00000333657	candidate	0	0	0	Last Universal Common Ancestor	1	1	Cell response to stimuli	99	chr21	42748834	42780157	WGS	lung
4602	MYB	v-myb myeloblastosis viral oncogene homolog (avian)	6q22-q23	01810	7545	189990	NP_001155129;NP_001155130;NP_001155132;NP_005366;NP_001155128;NP_001123644;NP_001155131;NP_001123645	NM_001161657;NM_001161658;NM_001161660;NM_005375;NM_001161656;NM_001130172;NM_001161659;NM_001130173	ENSP00000410825;ENSP00000339992;ENSP00000435938;ENSP00000356788	known	1	0	0	Eukaryotes	91	14	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	34	chr6	135507039	135539115	CGC	adenoid cystic carcinoma
4609	MYC	v-myc myelocytomatosis viral oncogene homolog (avian)	8q24.21	01818	7553	190080	NP_002458	NM_002467	ENSP00000367207	known	1	0	0	Eukaryotes	990	24	Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	61	chr8	128750491	128753201	CGC,WES,WGS,Amplified	leukemia,lymphoma,lung
23077	MYCBP2	MYC binding protein 2	13q22	10104	23386	610392	NP_055872	NM_015057	ENSP00000384288	candidate	0	0	0	Eukaryotes	29	1	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	87	chr13	77619516	77900910	WGS	breast
4610	MYCL1	v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian)	1p34.2	01279	7555	164850	NP_001028253;NP_001028254;NP_005367	NM_001033081;NM_001033082;NM_005376	ENSP00000380494;ENSP00000361902	known	1	0	1	Opisthokonts	2	1	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	84	chr1	40363047	40367560	CGC,WGS,Amplified	lung,liver
4613	MYCN	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)	2p24.3	01278	7559	164840	NP_005369	NM_005378	ENSP00000281043	known	1	0	0	Eukaryotes	23	12	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	11	chr2	16082187	16086216	CGC,Amplified	neuroblastoma
4615	MYD88	myeloid differentiation primary response gene (88)	3p22	03703	7562	602170	NP_001166037;NP_001166039;NP_001166038;NP_002459;NP_001166040	NM_001172566;NM_001172568;NM_001172567;NM_002468;NM_001172569	ENSP00000401399;ENSP00000379625	known	1	0	0	Metazoans	66	1	Cell cycle,Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Immune system response,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	109	chr3	38180153	38182774	CGC,WES,WGS	lymphoma,chronic lymphocytic leukemia,non-hodgkin lymphoma
4619	MYH1	myosin, heavy chain 1, skeletal muscle, adult	17p13.1	08872	7567	160730	NP_005954	NM_005963	ENSP00000226207	candidate	0	0	6	Last Universal Common Ancestor	11	1	Multicellular activities	14	chr17	10395736	10419959	WES	breast
4629	MYH11	myosin, heavy chain 11, smooth muscle	16p13.11	01174	7569	160745	NP_001035203;NP_074035;NP_001035202;NP_002465	NM_001040114;NM_022844;NM_001040113;NM_002474	ENSP00000407821;ENSP00000379616;ENSP00000300036;ENSP00000345136	known	1	0	2	Last Universal Common Ancestor	24	0	Cell cycle,Cell motility and interactions,Cellular processes,Development,Multicellular activities	52	chr16	15797851	15932109	CGC	leukemia
4620	MYH2	myosin, heavy chain 2, skeletal muscle, adult	17p13.1	01173	7572	160740	NP_001093582;NP_060004	NM_001100112;NM_017534	ENSP00000380367;ENSP00000245503	candidate	0	0	7	Last Universal Common Ancestor	14	1	Cellular processes,Multicellular activities	34	chr17	10424600	10451237	WES	pancreas
4622	MYH4	myosin, heavy chain 4, skeletal muscle	17p13.1	08873	7574	160742	NP_060003	NM_017533	ENSP00000255381	candidate	0	0	7	Last Universal Common Ancestor	3	1	Cellular processes,Multicellular activities	4	chr17	10346695	10370062	WES	pancreas
4624	MYH6	myosin, heavy chain 6, cardiac muscle, alpha	14q12	01171	7576	160710	NP_002462	NM_002471	ENSP00000386041	candidate	0	0	5	Last Universal Common Ancestor	2	0	Cellular processes,Development,Multicellular activities	6	chr14	23851637	23876432	WGS	glioblastoma
4626	MYH8	myosin, heavy chain 8, skeletal muscle, perinatal	17p13.1	11760	7578	160741	NP_002463	NM_002472	ENSP00000384330	candidate	0	0	7	Last Universal Common Ancestor	6	0	Multicellular activities	24	chr17	10293774	10323544	WGS	breast
4627	MYH9	myosin, heavy chain 9, non-muscle	22q13.1	01177	7579	160775	NP_002464	NM_002473	ENSP00000216181	known	1	0	2	Last Universal Common Ancestor	109	6	Cell motility and interactions,Cell response to stimuli,Cellular metabolism,Cellular processes,Development,Immune system response,Regulation of intracellular processes and metabolism,Signal transduction	104	chr22	36678717	36745281	CGC,WES	lymphoma,breast
340156	MYLK4	myosin light chain kinase family, member 4	6p25.2	17355	27972	-	NP_001012418	NM_001012418	ENSP00000274643	candidate	0	0	0	Last Universal Common Ancestor	2	0	Cellular metabolism,Cellular processes	-1	chr6	2671538	2749528	WES	breast
84700	MYO18B	myosin XVIIIB	22q12.1	09529	18150	607295	NP_115997	NM_032608	ENSP00000334563	candidate	0	0	0	Last Universal Common Ancestor	6	0	-1	-1	chr22	26157060	26423641	WES,WGS	breast,colorectal,prostate
80179	MYO19	myosin XIX	17q12	10107	26234	-	NP_001157207;NP_001028752;NP_079385	NM_001163735;NM_001033580;NM_025109;NM_001033579	ENSP00000409936;ENSP00000268852	candidate	0	0	0	Last Universal Common Ancestor	13	4	-1	51	chr17	34852098	34884042	WES	colorectal
4430	MYO1B	myosin IB	2q12-q34	08407	7596	606537	NP_001123630;NP_001155291;NP_036355	NM_001130158;NM_001161819;NM_012223	ENSP00000376132;ENSP00000306382;ENSP00000341903	candidate	0	0	0	Last Universal Common Ancestor	12	2	-1	93	chr2	192141622	192288683	WES	colorectal (hypermutated),glioblastoma
64005	MYO1G	myosin IG	7p13-p11.2	17622	13880	613445	NP_149043	NM_033054	ENSP00000258787	candidate	0	0	0	Last Universal Common Ancestor	7	0	-1	-1	chr7	45002341	45018560	WES	breast,lymphoma
53904	MYO3A	myosin IIIA	10p11.1	06008	7601	606808	NP_059129	NM_017433	ENSP00000265944	candidate	0	0	0	Last Universal Common Ancestor	2	0	Cell response to stimuli,Cellular metabolism,Cellular processes	5	chr10	26241040	26500889	WGS	prostate
4645	MYO5B	myosin VB	18q21	-	7603	606540	NP_001073936	NM_001080467	ENSP00000285039	candidate	0	0	0	Last Universal Common Ancestor	11	4	-1	-1	chr18	47352844	47581751	WGS	lymphoma
55930	MYO5C	myosin VC	15q21	11380	7604	610022	NP_061198	NM_018728	ENSP00000261839	candidate	0	0	0	Last Universal Common Ancestor	5	0	-1	98	chr15	52486102	52575092	WES	colorectal
4649	MYO9A	myosin IXA	15q22-q23	05341	7608	604875	NP_008832	NM_006901	ENSP00000398250	candidate	0	0	0	Last Universal Common Ancestor	6	6	Cell response to stimuli,Signal transduction	61	chr15	72118924	72338904	WGS	melanoma
9172	MYOM2	myomesin (M-protein) 2, 165kDa	8p23.3	04619	7614	603509	NP_003961	NM_003970	ENSP00000262113	candidate	0	0	0	Last Universal Common Ancestor	17	0	Multicellular activities	30	chr8	1998881	2092902	WES	lymphoma
127294	MYOM3	myomesin family, member 3	1p36.11	08200	26679	-	NP_689585	NM_152372	ENSP00000363557	candidate	0	0	0	Eukaryotes	2	0	-1	-1	chr1	24383857	24435126	WES	pancreas
4665	NAB2	NGFI-A binding protein 2 (EGR1 binding protein 2)	12q13.3	03854	7627	602381	NP_005958	NM_005967	ENSP00000300131	candidate	0	0	0	Metazoans	9	1	Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription	36	chr12	57483055	57488501	WGS	lymphoma
4666	NACA	nascent polypeptide-associated complex alpha subunit	12q23-q24.1	03137	7629	601234	NP_001106674;NP_001106672;NP_005585;NP_001106673	NM_001113203;NM_001113201;NM_005594;NR_045277;NM_001113202	ENSP00000448035	known	1	0	0	Last Universal Common Ancestor	32	2	Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of transcription	109	chr12	57106570	57118305	CGC	non-hodgkin lymphoma
259232	NALCN	sodium leak channel, non-selective	13q32.3	15647	19082	611549	NP_443099	NM_052867	ENSP00000251127	candidate	0	0	0	Eukaryotes	1	1	Cellular processes	-1	chr13	101707650	102051477	WES,WGS	pancreas,breast
55226	NAT10	N-acetyltransferase 10 (GCN5-related)	11p13	10964	29830	609221	NP_001137502;NP_078938	NM_001144030;NM_024662	ENSP00000433011;ENSP00000257829	candidate	0	0	0	Last Universal Common Ancestor	23	1	-1	106	chr11	34129773	34167736	WGS	prostate
10	NAT2	N-acetyltransferase 2 (arylamine N-acetyltransferase)	8p22	02000	7646	612182	NP_000006	NM_000015	ENSP00000286479	candidate	0	0	1	Last Universal Common Ancestor	2	0	-1	18	chr8	18257514	18258383	WGS	melanoma
89795	NAV3	neuron navigator 3	12q14.3	10114	15998	611629	NP_055718	NM_014903	ENSP00000381007	candidate	0	0	0	Eukaryotes	30	0	-1	32	chr12	78225242	78604294	WES	colorectal,head and neck squamous cell carcinoma,kidney
65065	NBEAL1	neurobeachin-like 1	2q33.2	14811	20681	609816	NP_001107604	NM_198945;NM_205543;NM_001114132;NM_001099273	ENSP00000399903	candidate	0	0	0	Last Universal Common Ancestor	1	0	-1	-1	chr2	203881108	204082074	WGS	prostate
4683	NBN	nibrin	8q21	04050	7652	602667	NP_002476	NM_001024688;NM_002485	ENSP00000265433	known	0	1	0	Opisthokonts	62	3	Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	101	chr8	90949253	90996789	CGC	
4685	NCAM2	neural cell adhesion molecule 2	21q21.1	03619	7657	602040	NP_004531	NM_004540	-	candidate	0	0	0	Eukaryotes	4	2	Cell motility and interactions	44	chr21	22370882	22910275	WES	lung
51517	NCKIPSD	NCK interacting protein with SH3 domain	3p21	09450	15486	606671	NP_057537;NP_909119	NM_016453;NM_184231	ENSP00000294129;ENSP00000389059	known	1	0	0	Opisthokonts	28	1	Cellular processes,Signal transduction	90	chr3	48711980	48723240	CGC	leukemia
8648	NCOA1	nuclear receptor coactivator 1	2p23	04070	7668	602691	NP_003734;NP_671766;NP_671756	NM_003743;NM_147233;NM_147223	ENSP00000320940;ENSP00000288599;ENSP00000379197	known	1	0	0	Eukaryotes	93	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	104	chr2	24881547	24991257	CGC	sarcoma
10499	NCOA2	nuclear receptor coactivator 2	8q13.3	09066	7669	601993	NP_006531	NM_006540	-	known	1	0	0	Eukaryotes	11	1	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	62	chr8	71033537	71128980	CGC	leukemia,sarcoma
8202	NCOA3	nuclear receptor coactivator 3	20q12	03570	7670	601937	NP_006525;NP_001167559;NP_858045;NP_001167558	NM_006534;NM_001174088;NM_181659;NM_001174087	ENSP00000361065;ENSP00000361073	known	0	0	0	Eukaryotes	116	12	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	100	chr20	46250992	46281816	CGC,Amplified	
8031	NCOA4	nuclear receptor coactivator 4	10q11.2	03584	7671	601984	NP_001138735;NP_001138733;NP_001138734;NP_001138732;NP_005428	NM_001145263;NM_001145261;NM_001145262;NM_001145260;NM_005437	ENSP00000395465;ENSP00000405146;ENSP00000390713;ENSP00000363200;ENSP00000344552	known	1	0	3	Metazoans	17	0	Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	109	chr10	51568357	51586672	CGC	thyroid
23054	NCOA6	nuclear receptor coactivator 6	20q11	05599	15936	605299	NP_001229468;NP_054790	NM_001242539;NM_014071	ENSP00000351894	candidate	0	0	0	Last Universal Common Ancestor	85	4	Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	106	chr20	33303129	33370158	WES	breast
9611	NCOR1	nuclear receptor corepressor 1	17p11.2	02911	7672	600849	NP_006302;NP_001177367;NP_001177369	NM_006311;NM_001190438;NM_001190440	ENSP00000379189;ENSP00000379192;ENSP00000268712	candidate	0	0	0	Last Universal Common Ancestor	174	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	104	chr17	15935613	16097883	WES,WGS	bladder,breast,prostate,lymphoma
10403	NDC80	NDC80 kinetochore complex component homolog (S. cerevisiae)	18p11.32	06277	16909	607272	NP_006092	NM_006101	ENSP00000261597	candidate	0	0	0	Eukaryotes	22	1	Cell cycle,Cellular processes,DNA/RNA metabolism and transcription,Signal transduction	7	chr18	2572985	2616570	WES	cholangiocarcinoma
10397	NDRG1	N-myc downstream regulated 1	8q24.3	05586	7679	605262	NP_006087;NP_001128714	NM_006096;NM_001135242	ENSP00000404854;ENSP00000437443;ENSP00000319977	known	1	0	0	Eukaryotes	59	2	Cell response to stimuli	107	chr8	134251124	134296554	CGC	prostate
4703	NEB	nebulin	2q22	01196	7720	161650	NP_004534;NP_001157980;NP_001157979	NM_004543;NM_001164508;NM_001164507	ENSP00000416578;ENSP00000380505;ENSP00000386259	candidate	0	0	0	Last Universal Common Ancestor	33	0	Cellular processes,Development,Regulation of intracellular processes and metabolism	34	chr2	152357902	152584420	WES	lymphoma
4744	NEFH	neurofilament, heavy polypeptide	22q12.2	01204	7737	162230	NP_066554	NM_021076	ENSP00000311997	candidate	0	0	0	Last Universal Common Ancestor	7	3	DNA/RNA metabolism and transcription,Development	45	chr22	29876252	29886689	WGS	prostate
4751	NEK2	NIMA (never in mitosis gene a)-related kinase 2	1q32.2-q41	04953	7745	604043	NP_001191112;NP_002488;NP_001191111	NM_001204183;NM_002497;NM_001204182	ENSP00000355965;ENSP00000355966	candidate	0	0	4	Last Universal Common Ancestor	38	2	Cell cycle,Cellular metabolism,Cellular processes	36	chr1	211836771	211848821	HTMS	breast,lung,ovarian,pancreas,prostate
284086	NEK8	NIMA (never in mitosis gene a)- related kinase 8	17q11.1	14822	13387	609799	NP_835464	NM_178170	-	candidate	0	0	0	Last Universal Common Ancestor	9	0	Cellular metabolism,Cellular processes	-1	chr17	27055832	27068588	WGS	liver
91754	NEK9	NIMA (never in mitosis gene a)- related kinase 9	14q24.3	11386	18591	609798	NP_149107	NM_033116	ENSP00000238616	candidate	0	0	0	Last Universal Common Ancestor	27	4	Cell cycle,Cellular metabolism,Cellular processes	92	chr14	75551270	75593624	WGS	lung
81831	NETO2	neuropilin (NRP) and tolloid (TLL)-like 2	16q11	09721	14644	607974	NP_060562;NP_001188406	NM_018092;NM_001201477	ENSP00000306726	candidate	0	0	1	Metazoans	1	6	-1	47	chr16	47117135	47165937	WES	head and neck squamous cell carcinoma
63973	NEUROG2	neurogenin 2	4q25	06976	13805	606624	NP_076924	NM_024019	ENSP00000317333	candidate	0	0	0	Metazoans	2	0	Cell cycle,Cell motility and interactions,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription	0	chr4	113435816	113436631	WES	melanoma
4763	NF1	neurofibromin 1	17q11.2	01203	7765	613113	NP_001035957;NP_000258;NP_001121619	NM_001042492;NM_000267;NM_001128147	ENSP00000348498;ENSP00000351015;ENSP00000412921	known	0	1	0	Eukaryotes	22	2	Cell cycle,Cell motility and interactions,Cell response to stimuli,Cellular processes,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction	86	chr17	29422328	29701170	CGC,HTMS,WES	glioma,neurofibroma,breast,glioblastoma,lung,ovarian,pancreas,prostate,sarcoma,bladder,colorectal
4771	NF2	neurofibromin 2 (merlin)	22q12.2	06980	7773	607379	NP_861546;NP_000259;NP_861969;NP_861967;NP_861971;NP_861968;NP_861970;NP_057502;NP_861966	NM_181825;NM_000268;NM_181831;NM_181829;NM_181833;NM_181830;NM_181832;NM_016418;NM_181827;NM_181834;NM_181835;NM_181826;NM_181828	ENSP00000344666;ENSP00000384797;ENSP00000354897;ENSP00000335652;ENSP00000409921	known	0	1	0	Eukaryotes	12	4	Cell cycle,Cell motility and interactions,Cell response to stimuli,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	56	chr22	29999988	30090788	CGC,HTMS	acoustic neuroma,kidney,meningioma
4780	NFE2L2	nuclear factor (erythroid-derived 2)-like 2	2q31	02732	7782	600492	NP_001138884;NP_001138885;NP_006155	NM_001145412;NM_001145413;NM_006164	ENSP00000380253;ENSP00000411575;ENSP00000380252	known	1	0	0	Eukaryotes	50	6	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	103	chr2	178095516	178129304	CGC,WES	head and neck squamous cell carcinoma,lung,liver,pancreas
9603	NFE2L3	nuclear factor (erythroid-derived 2)-like 3	7p15.2	09162	7783	604135	NP_004280	NM_004289	ENSP00000056233	candidate	0	0	2	Eukaryotes	4	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	63	chr7	26192119	26225400	WES	melanoma
4781	NFIB	nuclear factor I/B	9p24.1	09008	7785	600728	NP_001177666;NP_005587;NP_001177667	NM_001190737;NM_005596;NM_001190738	ENSP00000370321;ENSP00000370346	known	1	0	0	Metazoans	8	9	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	96	chr9	14112998	14307540	CGC	adenoid cystic carcinoma,lipoma
4791	NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)	10q24	01239	7795	164012	NP_001070961;NP_001070962;NP_002493	NM_001077493;NM_001077494;NM_002502	ENSP00000358983;ENSP00000189444	known	1	0	0	Last Universal Common Ancestor	102	2	Cell motility and interactions,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Immune system response,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	48	chr10	104156004	104162130	CGC	non-hodgkin lymphoma
4792	NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	14q13	01235	7797	164008	NP_065390	NM_020529	ENSP00000216797	candidate	0	0	0	Last Universal Common Ancestor	60	4	Cell cycle,Cell response to stimuli,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Signal transduction	109	chr14	35871222	35873850	WES	lymphoma
25791	NGEF	neuronal guanine nucleotide exchange factor	2q37	10442	7807	605991	NP_001107562;NP_062824	NM_001114090;NM_019850	ENSP00000362653;ENSP00000264051	candidate	0	0	0	Eukaryotes	11	0	Development,Signal transduction	-1	chr2	233744202	233839600	WES	glioblastoma
51199	NIN	ninein (GSK3B interacting protein)	14q22.1	09785	14906	608684	NP_891991;NP_065972;NP_057434;NP_891989	NM_182946;NM_020921;NM_016350;NM_182944;NM_182945	ENSP00000371474;ENSP00000245441;ENSP00000412391;ENSP00000371472	known	1	0	0	Metazoans	15	14	Cellular metabolism,Cellular processes,Signal transduction	14	chr14	51190184	51288774	CGC	myeloma
81614	NIPA2	non imprinted in Prader-Willi/Angelman syndrome 2	15q11.2	16290	17044	608146	NP_001171817;NP_001008860;NP_112184;NP_001008894;NP_001171818;NP_001008892	NM_001184888;NM_001008860;NM_030922;NM_001008894;NM_001184889;NM_001008892	ENSP00000381096;ENSP00000337618	candidate	0	0	1	Eukaryotes	1	0	-1	94	chr15	23006224	23021336	WES,WGS	prostate,chronic lymphocytic leukemia
7080	NKX2-1	NK2 homeobox 1	14q13	02798	11825	600635	NP_001073136;NP_003308	NM_001079668;NM_003317	ENSP00000346879;ENSP00000429607	known	1	0	0	Eukaryotes	21	2	Cell cycle,Cell motility and interactions,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription	22	chr14	36986486	36989334	CGC,WES,Amplified	lung
26257	NKX2-8	NK2 homeobox 8	14q13.3	04456	16364	603245	NP_055175	NM_014360	ENSP00000258829	known	0	0	0	Eukaryotes	0	0	Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription	4	chr14	37050110	37051594	CGC,Amplified	
22871	NLGN1	neuroligin 1	3q26.31	07195	14291	600568	NP_055747	NM_014932	ENSP00000354541	candidate	0	0	3	Last Universal Common Ancestor	6	0	Cell cycle,Cell motility and interactions,Cellular processes,Development,Multicellular activities,Signal transduction	36	chr3	173322389	173999090	WGS	lung
57486	NLN	neurolysin (metallopeptidase M3 family)	5q12.3	07495	16058	611530	NP_065777	NM_020726	ENSP00000370372	candidate	0	0	0	Last Universal Common Ancestor	5	0	Cellular metabolism	-1	chr5	65054386	65118740	WES	chronic lymphocytic leukemia
22861	NLRP1	NLR family, pyrin domain containing 1	17p13.2	07364	14374	606636	NP_127499;NP_001028225;NP_127497;NP_127500;NP_055737	NM_033006;NM_001033053;NM_033004;NM_033007;NM_014922	ENSP00000262467;ENSP00000324366	candidate	0	0	0	Eukaryotes	17	1	Cell cycle,Development,Regulation of intracellular processes and metabolism,Signal transduction	92	chr17	5418077	5487277	WES	liver
114548	NLRP3	NLR family, pyrin domain containing 3	1q44	05915	16400	606416	NP_899632;NP_004886;NP_001120933;NP_001073289;NP_001230062;NP_001120934	NM_183395;NM_004895;NM_001127461;NM_001079821;NM_001243133;NM_001127462	ENSP00000375704;ENSP00000355453;ENSP00000337383;ENSP00000294752	candidate	0	0	0	Last Universal Common Ancestor	7	1	Cell cycle,Cell response to stimuli,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Immune system response,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	8	chr1	247582097	247611803	HTMS	breast,lung,ovarian,pancreas,prostate
126205	NLRP8	NLR family, pyrin domain containing 8	19q13.43	14807	22940	609659	NP_789781	NM_176811	ENSP00000291971	candidate	0	0	0	Eukaryotes	0	0	-1	-1	chr19	56459269	56499276	WES	medulloblastoma
347736	NME9	NME gene family member 9	3q22.3	18250	21343	-	NP_835231	NM_178130	ENSP00000372667	candidate	0	0	0	Last Universal Common Ancestor	1	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism	-1	chr3	138022332	138038427	WGS	breast
10392	NOD1	nucleotide-binding oligomerization domain containing 1	7p15-p14	05815	16390	605980	NP_006083	NM_006092	ENSP00000222823	candidate	0	0	0	Eukaryotes	8	0	Cell cycle,Cell response to stimuli,Cellular metabolism,Immune system response,Regulation of intracellular processes and metabolism,Signal transduction	56	chr7	30465257	30496537	WGS	lymphoma
4841	NONO	non-POU domain containing, octamer-binding	Xq13.1	02098	7871	300084	NP_031389;NP_001138882;NP_001138881;NP_001138880	NM_007363;NM_001145410;NM_001145409;NM_001145408	ENSP00000362947;ENSP00000441364;ENSP00000276079	known	1	0	1	Vertebrates	126	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	109	chrX	70510488	70519923	CGC	kidney
4846	NOS3	nitric oxide synthase 3 (endothelial cell)	7q36	01224	7876	163729	NP_000594;NP_001153581;NP_001153582;NP_001153583	NM_000603;NM_001160109;NM_001160110;NM_001160111	ENSP00000297494;ENSP00000420551;ENSP00000420215	candidate	0	0	0	Last Universal Common Ancestor	64	2	Cell cycle,Cellular metabolism,Cellular processes,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction	16	chr7	150690892	150711254	WES	colorectal
4851	NOTCH1	notch 1	9q34.3	01827	7881	190198	NP_060087	NM_017617	ENSP00000277541	known	1	0	0	Last Universal Common Ancestor	78	13	Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	77	chr9	139390526	139440238	CGC,WES,WGS	leukemia,breast,chronic lymphocytic leukemia,head and neck squamous cell carcinoma,lung,lymphoma,oligodendroglioma
4853	NOTCH2	notch 2	1p13-p11	02606	7882	600275	NP_001186930;NP_077719	NM_001200001;NM_024408	ENSP00000256646	known	1	0	0	Last Universal Common Ancestor	30	12	Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	108	chr1	120457932	120612020	CGC	lymphoma
4857	NOVA1	neuro-oncological ventral antigen 1	14q	03693	7886	602157	NP_006482;NP_006480;NP_002506	NM_006491;NM_006489;NM_002515	ENSP00000438875;ENSP00000447391	candidate	0	0	0	Eukaryotes	5	2	DNA/RNA metabolism and transcription,Multicellular activities,Regulation of transcription	71	chr14	26917168	27066642	WGS	liver
50508	NOX3	NADPH oxidase 3	6q25.3	06165	7890	607105	NP_056533	NM_015718	ENSP00000159060	candidate	0	0	0	Last Universal Common Ancestor	0	1	Regulation of intracellular processes and metabolism	0	chr6	155717973	155776934	WGS	prostate
261734	NPHP4	nephronophthisis 4	1p36	06238	19104	607215	NP_055917	NM_015102	ENSP00000367398	candidate	0	0	0	Eukaryotes	6	0	Cell response to stimuli,Cellular processes,Multicellular activities,Signal transduction	58	chr1	5923328	6046349	WGS	glioblastoma,prostate
4869	NPM1	nucleophosmin (nucleolar phosphoprotein B23, numatrin)	5q35.1	01246	7910	164040	NP_954654;NP_001032827;NP_002511	NM_199185;NM_001037738;NM_002520	ENSP00000296930;ENSP00000341168	known	1	0	31	Metazoans	62	0	Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	109	chr5	93018546	93019423	CGC,WGS	leukemia,non-hodgkin lymphoma,acute myeloid leukemia
387129	NPSR1	neuropeptide S receptor 1	7p14.3	10547	23631	608595	NP_997056;NP_997055	NM_207173;NM_207172	ENSP00000353788;ENSP00000352839	candidate	0	0	0	Metazoans	0	0	Signal transduction	-1	chr7	34698025	34917793	WGS	melanoma
4887	NPY2R	neuropeptide Y receptor Y2	4q31	01216	7957	162642	NP_000901	NM_000910	ENSP00000332591	candidate	0	0	0	Metazoans	0	0	Signal transduction	59	chr4	156135092	156136234	HTMS	breast,lung,ovarian,pancreas,prostate
4889	NPY5R	neuropeptide Y receptor Y5	4q31-q32	03591	7958	602001	NP_006165	NM_006174	ENSP00000339377	candidate	0	0	0	Metazoans	5	0	Multicellular activities,Signal transduction	61	chr4	164271426	164272760	HTMS	breast,lung,ovarian,pancreas,prostate
8013	NR4A3	nuclear receptor subfamily 4, group A, member 3	9q22	02766	7982	600542	NP_775292;NP_775291;NP_008912	NM_173200;NM_173198;NM_173199;NM_006981	ENSP00000340301;ENSP00000333122	known	1	0	0	Metazoans	12	4	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	55	chr9	102590322	102626146	CGC	sarcoma
4893	NRAS	neuroblastoma RAS viral (v-ras) oncogene homolog	1p13.2	01273	7989	164790	NP_002515	NM_002524	ENSP00000358548	known	1	0	2	Last Universal Common Ancestor	38	9	Cell cycle,Cell response to stimuli,Cellular processes,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction	52	chr1	115251159	115258781	CGC,HTMS,WES,WGS	leukemia,melanoma,myeloma,thyroid,lung,colorectal (non-hypermutated),myelodysplasia,acute myeloid leukemia
9542	NRG2	neuregulin 2	5q23-q33	04821	7998	603818	NP_053586;NP_053585;NP_004874;NP_053584;NP_001171864	NM_013983;NM_013982;NM_013984;NM_004883;NM_013985;NM_013981;NM_001184935	ENSP00000444235	candidate	0	0	0	Eukaryotes	2	0	Signal transduction	24	chr5	139227505	139422654	WES	pancreas
10718	NRG3	neuregulin 3	10q22-q23	16115	7999	605533	NP_001010848;NP_001159445;NP_001159444	NM_001010848;NM_001165973;NM_001165972	ENSP00000361215	candidate	0	0	0	Metazoans	1	0	Cell cycle,Development,Regulation of intracellular processes and metabolism,Signal transduction	-1	chr10	83635097	84745358	HTMS	breast,lung,ovarian,pancreas,prostate
203447	NRK	Nik related kinase	Xq22.3	14841	25391	300791	NP_940867	NM_198465	ENSP00000434830	candidate	0	0	0	Last Universal Common Ancestor	1	1	Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	-1	chrX	105066839	105199589	WES,WGS	head and neck squamous cell carcinoma,breast
9379	NRXN2	neurexin 2	11q13	11859	8009	600566	NP_055895;NP_620060;NP_620063	NM_015080;NM_138732;NM_138734	ENSP00000265459;ENSP00000366782;ENSP00000301894	candidate	0	0	0	Metazoans	11	0	Cellular processes,Development,Multicellular activities,Signal transduction	38	chr11	64374671	64481171	WES	head and neck squamous cell carcinoma
9369	NRXN3	neurexin 3	14q31	08989	8010	600567	NP_620426;NP_001098720;NP_004787	NM_138970;NM_001105250;NM_004796	ENSP00000394426;ENSP00000281127	candidate	0	0	1	Metazoans	7	1	Cell cycle,Cell motility and interactions,Development	21	chr14	79117568	80328304	WES	head and neck squamous cell carcinoma
64324	NSD1	nuclear receptor binding SET domain protein 1	5q35	09455	14234	606681	NP_071900;NP_758859	NM_022455;NM_172349	ENSP00000395929;ENSP00000346111	known	1	0	0	Last Universal Common Ancestor	14	0	Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	46	chr5	176562105	176722457	CGC,WES	leukemia,head and neck squamous cell carcinoma
64943	NT5DC2	5'-nucleotidase domain containing 2	3p21.1	07770	25717	-	NP_001127703;NP_075059	NM_001134231;NM_022908	ENSP00000406933;ENSP00000302468	candidate	0	0	0	Eukaryotes	8	1	-1	52	chr3	52558489	52567753	WGS	lymphoma
22854	NTNG1	netrin G1	1p13.3	16389	23319	608818	NP_001106697;NP_001106699;NP_055732	NM_001113226;NM_001113228;NM_014917	ENSP00000359090;ENSP00000359088;ENSP00000359091	candidate	0	0	0	Metazoans	3	1	Cell cycle,Development	54	chr1	107691216	108023459	WES	colorectal
4914	NTRK1	neurotrophic tyrosine kinase, receptor, type 1	1q21-q22	01869	8031	191315	NP_001012331;NP_001007793;NP_002520	NM_001012331;NM_001007792;NM_002529	ENSP00000376120;ENSP00000357179;ENSP00000431418	known	1	0	0	Last Universal Common Ancestor	60	0	Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction	0	chr1	156830727	156851431	CGC,HTMS	thyroid,lung,sarcoma
4915	NTRK2	neurotrophic tyrosine kinase, receptor, type 2	9q22.1	02712	8032	600456	NP_001007098;NP_006171;NP_001018074;NP_001018076;NP_001018075	NM_001007097;NM_006180;NM_001018064;NM_001018066;NM_001018065	ENSP00000379221;ENSP00000365386;ENSP00000306167;ENSP00000365381;ENSP00000365387	candidate	0	0	0	Last Universal Common Ancestor	21	1	Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction	94	chr9	87285664	87636349	WGS	liver
4916	NTRK3	neurotrophic tyrosine kinase, receptor, type 3	15q25	01870	8033	191316	NP_001230030;NP_002521;NP_001007157;NP_001012338	NM_001243101;NM_002530;NM_001007156;NM_001012338	ENSP00000318328;ENSP00000354207;ENSP00000453959;ENSP00000347397	known	1	0	0	Last Universal Common Ancestor	4	18	Cellular metabolism,Cellular processes,Development,Signal transduction	97	chr15	88420169	88799384	CGC,HTMS	breast,sarcoma,lung
55190	NUDT11	nudix (nucleoside diphosphate linked moiety X)-type motif 11	Xp11.22	06667	18011	300528	NP_060629	NM_018159	ENSP00000365160	candidate	0	0	4	Eukaryotes	2	0	-1	32	chrX	51238805	51239296	WES	head and neck squamous cell carcinoma
256281	NUDT14	nudix (nucleoside diphosphate linked moiety X)-type motif 14	14q32.33	14847	20141	609219	NP_803877	NM_177533	ENSP00000376349	candidate	0	0	0	Last Universal Common Ancestor	6	0	-1	-1	chr14	105639361	105647546	WES	head and neck squamous cell carcinoma
4926	NUMA1	nuclear mitotic apparatus protein 1	11q13	01236	8059	164009	NP_006176	NM_006185	ENSP00000377298	known	1	0	0	Last Universal Common Ancestor	10	1	Cell cycle,Cellular processes	83	chr11	71714933	71746989	CGC,WGS	leukemia,lung
55746	NUP133	nucleoporin 133kDa	1q42.13	06354	18016	607613	NP_060700	NM_018230	ENSP00000261396	candidate	0	0	0	Eukaryotes	27	0	Cellular processes,DNA/RNA metabolism and transcription	88	chr1	229577654	229643996	WES	breast
23225	NUP210	nucleoporin 210kDa	3p25.1	06368	30052	607703	NP_079199	NM_024923	ENSP00000254508	candidate	0	0	0	Eukaryotes	18	3	Cellular processes,DNA/RNA metabolism and transcription	91	chr3	13359184	13461726	WES	colorectal
8021	NUP214	nucleoporin 214kDa	9q34.1	00258	8064	114350	NP_005076	NM_005085	ENSP00000352400	known	1	0	0	Last Universal Common Ancestor	54	1	Cellular processes,DNA/RNA metabolism and transcription	82	chr9	134001092	134106158	CGC,WES	leukemia,breast
4928	NUP98	nucleoporin 98kDa	11p15.5	03012	8068	601021	NP_005378;NP_624358;NP_624357;NP_057404	NM_005387;NM_139132;NM_139131;NM_016320	ENSP00000380202;ENSP00000316032;ENSP00000380199;ENSP00000347404	known	1	0	0	Last Universal Common Ancestor	12	2	Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription	74	chr11	3697392	3803347	CGC	leukemia
10482	NXF1	nuclear RNA export factor 1	11q12-q13	04035	8071	602647	NP_006353;NP_001074960	NM_006362;NM_001081491	ENSP00000453885;ENSP00000294172	candidate	0	0	0	Eukaryotes	126	0	Cellular processes,DNA/RNA metabolism and transcription	106	chr11	62560113	62571451	WES	chronic lymphocytic leukemia
11249	NXPH2	neurexophilin 2	2q22.1	11983	8076	604635	NP_009157	NM_007226	-	candidate	0	0	0	Vertebrates	4	2	Signal transduction	-1	chr2	139428495	139537811	WGS	melanoma
84033	OBSCN	obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF	1q42.13	10551	15719	608616	NP_443075;NP_001092093	NM_052843;NM_001098623	ENSP00000409493;ENSP00000455507;ENSP00000284548	candidate	0	0	0	Last Universal Common Ancestor	17	1	Cellular metabolism,Cellular processes,Signal transduction	2	chr1	228399485	228566493	WGS	melanoma
729330	OC90	otoconin 90	8q24.22	-	8100	601658	NP_001073868	NM_001080399	ENSP00000254627	candidate	0	0	0	Vertebrates	2	0	Cellular metabolism	-1	chr8	133036731	133067273	WGS	melanoma
8481	OFD1	oral-facial-digital syndrome 1	Xp22	02162	2567	300170	NP_003602	NM_003611	ENSP00000344314	candidate	0	0	1	Eukaryotes	9	1	-1	90	chrX	13753367	13787224	WES	lymphoma
4969	OGN	osteoglycin	9q22	03856	8126	602383	NP_148935;NP_054776	NM_024416;NM_033014;NM_014057	ENSP00000364711;ENSP00000262551	candidate	0	0	0	Eukaryotes	3	0	-1	15	chr9	95147905	95165689	WGS	prostate
10215	OLIG2	oligodendrocyte lineage transcription factor 2	21q22.11	07334	9398	606386	NP_005797	NM_005806	ENSP00000371794	known	1	0	0	Metazoans	5	2	Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription	50	chr21	34399171	34400139	CGC	leukemia
4958	OMD	osteomodulin	9q22.31	10128	8134	-	NP_005005	NM_005014	ENSP00000364700	known	1	0	0	Last Universal Common Ancestor	0	0	-1	41	chr9	95177437	95179840	CGC	bone cyst
282770	OR10AG1	olfactory receptor, family 10, subfamily AG, member 1	11q11	14885	19607	-	NP_001005491	NM_001005491	ENSP00000311477	candidate	0	0	0	Mammals	0	0	Cell response to stimuli,Signal transduction	-1	chr11	55735037	55735939	WES	melanoma
390265	OR10G7	olfactory receptor, family 10, subfamily G, member 7	11q24.2	14890	14842	-	NP_001004463	NM_001004463	ENSP00000329689	candidate	0	0	4	Mammals	0	0	Cell response to stimuli,Signal transduction	-1	chr11	123908776	123909708	WES	lung
219870	OR10G9	olfactory receptor, family 10, subfamily G, member 9	11q24.1	17666	15129	-	NP_001001953	NM_001001953	ENSP00000364164	candidate	0	0	3	Mammals	0	0	Cell response to stimuli,Signal transduction	-1	chr11	123893720	123894652	WES	melanoma
343406	OR10R2	olfactory receptor, family 10, subfamily R, member 2	1q23.1	17674	14820	-	NP_001004472	NM_001004472	ENSP00000357134	candidate	0	0	1	Mammals	0	0	Signal transduction	-1	chr1	158449668	158450672	WES	pancreas
391189	OR11L1	olfactory receptor, family 11, subfamily L, member 1	1q44	17677	14998	-	NP_001001959	NM_001001959	ENSP00000348033	candidate	0	0	0	Metazoans	0	0	Cell response to stimuli,Signal transduction	-1	chr1	248004233	248005198	WES	lung
26740	OR1J2	olfactory receptor, family 1, subfamily J, member 2	9q34.11	14917	8209	-	NP_473448	NM_054107	ENSP00000335575	candidate	0	0	2	Mammals	4	1	Cell response to stimuli,Signal transduction	-1	chr9	125273081	125274019	WGS	melanoma
138881	OR1L8	olfactory receptor, family 1, subfamily L, member 8	9q33.2	14923	15110	-	NP_001004454	NM_001004454	ENSP00000306607	candidate	0	0	4	Metazoans	0	0	Cell response to stimuli,Signal transduction	-1	chr9	125329830	125330756	WGS	chronic lymphocytic leukemia
125963	OR1M1	olfactory receptor, family 1, subfamily M, member 1	19p13.2	17689	8220	-	NP_001004456	NM_001004456	ENSP00000401966	candidate	0	0	0	Mammals	4	0	Cell response to stimuli,Signal transduction	-1	chr19	9203921	9204859	WES	melanoma
442361	OR2A2	olfactory receptor, family 2, subfamily A, member 2	7q35	14931	8230	-	NP_001005480	NM_001005480	ENSP00000386209	candidate	0	0	8	Mammals	0	0	Cell response to stimuli,Signal transduction	-1	chr7	143806676	143807629	WES	melanoma
402317	OR2A42	olfactory receptor, family 2, subfamily A, member 42	7q35	18486	31230	-	NP_001001802	NM_001001802	ENSP00000375334	candidate	0	0	10	Vertebrates	0	0	Cell response to stimuli,Cellular metabolism,Signal transduction	-1	chr7	144015218	144016147	WES	melanoma
284521	OR2L13	olfactory receptor, family 2, subfamily L, member 13	1q44	17702	19578	-	NP_787107	NM_175911	ENSP00000355434	candidate	0	0	6	Mammals	1	0	Cell response to stimuli,Signal transduction	-1	chr1	248262678	248263613	WES	glioblastoma
26245	OR2M4	olfactory receptor, family 2, subfamily M, member 4	1q44	14946	8270	-	NP_059974	NM_017504	ENSP00000306688	candidate	0	0	5	Eukaryotes	0	0	Cell response to stimuli,Signal transduction	-1	chr1	248402231	248403163	WES	chronic lymphocytic leukemia
127077	OR2T11	olfactory receptor, family 2, subfamily T, member 11	1q44	17705	19574	-	NP_001001964	NM_001001964	ENSP00000328934	candidate	0	0	5	Mammals	0	0	Cell response to stimuli,Signal transduction	-1	chr1	248789482	248790429	WGS	lung
391195	OR2T33	olfactory receptor, family 2, subfamily T, member 33	1q44	14953	31255	-	NP_001004695	NM_001004695	ENSP00000324687	candidate	0	0	3	Mammals	0	0	Cell response to stimuli,Signal transduction	-1	chr1	248436157	248437116	WGS	melanoma
127068	OR2T34	olfactory receptor, family 2, subfamily T, member 34	1q44	14954	31256	-	NP_001001821	NM_001001821	ENSP00000330904	candidate	0	0	4	Vertebrates	0	0	Cell response to stimuli,Signal transduction	-1	chr1	248737105	248738058	WGS	lymphoma
283092	OR4C13	olfactory receptor, family 4, subfamily C, member 13	11p11.12	17720	15169	-	NP_001001955	NM_001001955	ENSP00000452277	candidate	0	0	12	Mammals	0	0	Cell response to stimuli,Signal transduction	-1	chr11	49973975	49974901	WES	melanoma
81309	OR4C15	olfactory receptor, family 4, subfamily C, member 15	11q11	14963	15171	-	NP_001001920	NM_001001920	ENSP00000324958	candidate	0	0	0	Mammals	0	0	Cell response to stimuli,Signal transduction	-1	chr11	55321783	55322892	WES	gastric,head and neck squamous cell carcinoma
119749	OR4C46	olfactory receptor, family 4, subfamily C, member 46	11p11.12	14964	31271	614273	NP_001004703	NM_001004703	ENSP00000329056	candidate	0	0	12	Mammals	0	0	Cell response to stimuli,Signal transduction	-1	chr11	51515282	51516208	WES	gastric
219432	OR4C6	olfactory receptor, family 4, subfamily C, member 6	11q11	17724	14743	-	NP_001004704	NM_001004704	ENSP00000324769	candidate	0	0	9	Mammals	0	0	Cell response to stimuli,Signal transduction	-1	chr11	55432643	55433569	WES	melanoma
219986	OR4D11	olfactory receptor, family 4, subfamily D, member 11	11q12.1	17725	15174	-	NP_001004706	NM_001004706	ENSP00000320077	candidate	0	0	4	Mammals	0	0	Cell response to stimuli,Signal transduction	-1	chr11	59271049	59271981	WGS	melanoma
79544	OR4K1	olfactory receptor, family 4, subfamily K, member 1	14q11.2	14975	14726	-	NP_001004063	NM_001004063	ENSP00000285600	candidate	0	0	5	Mammals	0	0	Cell response to stimuli,Signal transduction	-1	chr14	20403826	20404758	WES	melanoma
122740	OR4K14	olfactory receptor, family 4, subfamily K, member 14	14q11.2	14977	15352	-	NP_001004712	NM_001004712	ENSP00000305011	candidate	0	0	0	Mammals	0	0	Cell response to stimuli,Signal transduction	-1	chr14	20482423	20483352	WES	melanoma
122742	OR4L1	olfactory receptor, family 4, subfamily L, member 1	14q11.2	14982	15356	-	NP_001004717	NM_001004717	ENSP00000319217	candidate	0	0	0	Mammals	0	0	Cell response to stimuli,Signal transduction	-1	chr14	20528204	20529139	WES	pancreas
390437	OR4N5	olfactory receptor, family 4, subfamily N, member 5	14q11.2	14985	15358	-	NP_001004724	NM_001004724	ENSP00000332110	candidate	0	0	5	Mammals	0	0	Cell response to stimuli,Signal transduction	-1	chr14	20611895	20612818	WGS	glioblastoma
441669	OR4Q3	olfactory receptor, family 4, subfamily Q, member 3	14q11.2	17732	15426	-	NP_751944	NM_172194	ENSP00000330049	candidate	0	0	1	Vertebrates	0	0	Cell response to stimuli,Signal transduction	-1	chr14	20215587	20216525	WGS	breast
219431	OR4S2	olfactory receptor, family 4, subfamily S, member 2	11q11	14988	15183	-	NP_001004059	NM_001004059	ENSP00000310337	candidate	0	0	1	Vertebrates	3	0	Cell response to stimuli,Signal transduction	-1	chr11	55418380	55419312	WGS	melanoma
143503	OR51E1	olfactory receptor, family 51, subfamily E, member 1	11p15.4	14996	15194	611267	NP_689643	NM_152430	ENSP00000380155	candidate	0	0	0	Vertebrates	0	0	Cell response to stimuli,Signal transduction	-1	chr11	4673757	4674710	WES	colorectal
390064	OR51I2	olfactory receptor, family 51, subfamily I, member 2	11p15.4	15000	15201	-	NP_001004754	NM_001004754	ENSP00000341987	candidate	0	0	1	Vertebrates	0	0	Cell response to stimuli,Signal transduction	-1	chr11	5474719	5475654	WES	melanoma
390054	OR52A5	olfactory receptor, family 52, subfamily A, member 5	11p15.4	15005	19580	-	NP_001005160	NM_001005160	ENSP00000303469	candidate	0	0	2	Metazoans	0	0	Cell response to stimuli,Signal transduction	-1	chr11	5152925	5153872	WGS	lung
390079	OR52E8	olfactory receptor, family 52, subfamily E, member 8	11p15.4	15013	15217	-	NP_001005168	NM_001005168	ENSP00000444054	candidate	0	0	6	Metazoans	0	0	Cell response to stimuli,Signal transduction	-1	chr11	5877982	5878932	WES	melanoma
219965	OR5B17	olfactory receptor, family 5, subfamily B, member 17	11q12.1	15036	15267	-	NP_001005489	NM_001005489	ENSP00000349945	candidate	0	0	5	Mammals	0	0	Cell response to stimuli,Signal transduction	-1	chr11	58125601	58126542	WES	lung
79310	OR5H2	olfactory receptor, family 5, subfamily H, member 2	3q12.1	15042	14752	-	NP_001005482	NM_001005482	ENSP00000347418	candidate	0	0	9	Mammals	0	0	Signal transduction	-1	chr3	98001732	98002673	WGS	melanoma
219437	OR5L1	olfactory receptor, family 5, subfamily L, member 1	11q11	15045	8350	-	NP_001004738	NM_001004738	ENSP00000335529	candidate	0	0	2	Metazoans	150	0	Cell response to stimuli,Signal transduction	-1	chr11	55578943	55579875	WES	melanoma,prostate
26338	OR5L2	olfactory receptor, family 5, subfamily L, member 2	11q11	15046	8351	-	NP_001004739	NM_001004739	ENSP00000367650	candidate	0	0	1	Metazoans	3	0	Cell response to stimuli,Signal transduction	-1	chr11	55594695	55595627	WES	head and neck squamous cell carcinoma
390166	OR5M5P	olfactory receptor, family 5, subfamily M, member 5 pseudogene	11q12.1	-	14810	-	-	-	-	candidate	0	0	-1	Mammals	0	0	-1	-1	-	0	0	WGS	lung
8590	OR6A2	olfactory receptor, family 6, subfamily A, member 2	11p15	09771	15301	608495	NP_003687	NM_003696	ENSP00000330384	candidate	0	0	0	Mammals	0	0	Cell response to stimuli,Signal transduction	38	chr11	6815959	6816939	WES	breast
391114	OR6K3	olfactory receptor, family 6, subfamily K, member 3	1q23.1	15064	15030	-	NP_001005327	NM_001005327	ENSP00000357127	candidate	0	0	2	Metazoans	0	0	Signal transduction	-1	chr1	158686961	158687905	WES	lymphoma
390151	OR8H2	olfactory receptor, family 8, subfamily H, member 2	11q12.1	15083	15308	-	NP_001005200	NM_001005200	ENSP00000323982	candidate	0	0	2	Vertebrates	0	0	Cell response to stimuli,Signal transduction	-1	chr11	55872519	55873454	WES	head and neck squamous cell carcinoma
390157	OR8K1	olfactory receptor, family 8, subfamily K, member 1	11q12.1	15086	14831	-	NP_001002907	NM_001002907	ENSP00000279783	candidate	0	0	3	Mammals	0	0	Cell response to stimuli,Signal transduction	-1	chr11	56113515	56114471	WES	head and neck squamous cell carcinoma
4998	ORC1	origin recognition complex, subunit 1	1p32	03544	8487	601902	NP_001177748;NP_004144;NP_001177747	NM_001190819;NM_004153;NM_001190818	ENSP00000360621;ENSP00000360623	candidate	0	0	0	Last Universal Common Ancestor	20	2	Cellular metabolism,DNA/RNA metabolism and transcription	14	chr1	52838856	52867895	WGS	prostate
9381	OTOF	otoferlin	2p23.1	04727	8515	603681	NP_004793;NP_919304;NP_919224;NP_919303	NM_004802;NM_194323;NM_194248;NM_194322	ENSP00000345137;ENSP00000272371;ENSP00000383906;ENSP00000344521	candidate	0	0	0	Eukaryotes	2	0	Cell response to stimuli,Cellular processes	0	chr2	26682896	26781439	WES	breast
283310	OTOGL	otogelin-like	12q21.31	08815	26901	-	NP_775862	NM_173591	ENSP00000400895	candidate	0	0	0	-	0	1	Cellular metabolism	-1	chr12	80603239	80771825	WES	chronic lymphocytic leukemia
133060	OTOP1	otopetrin 1	4p16.3	07421	19656	607806	NP_819056	NM_177998	ENSP00000296358	candidate	0	0	1	Vertebrates	0	0	Development	-1	chr4	4190533	4228591	WGS	liver
341350	OVCH1	ovochymase 1	12p11.22	07138	23080	-	NP_899234	NM_183378	ENSP00000326708	candidate	0	0	0	Last Universal Common Ancestor	1	0	Cellular metabolism	-1	chr12	29586684	29650619	WES	pancreas
5018	OXA1L	oxidase (cytochrome c) assembly 1-like	14q11.2	03043	8526	601066	NP_005006	NM_005015	ENSP00000285848	candidate	0	0	0	Last Universal Common Ancestor	18	3	Cellular metabolism,Cellular processes	97	chr14	23235731	23240764	WGS	glioblastoma
5027	P2RX7	purinergic receptor P2X, ligand-gated ion channel, 7	12q24	03977	8537	602566	NP_002553	NR_033952;NM_177427;NR_033951;NR_033953;NR_033949;NR_033950;NR_033955;NR_033948;NR_033956;NM_002562;NR_033954	-	candidate	0	0	0	Metazoans	10	2	Cell cycle,Cell response to stimuli,Cellular metabolism,Cellular processes,Development,Multicellular activities,Other,Regulation of intracellular processes and metabolism,Signal transduction	29	chr12	121570774	121622602	WES	colorectal
5031	P2RY6	pyrimidinergic receptor P2Y, G-protein coupled, 6	11q13.5	03906	8543	602451	NP_789767;NP_004145;NP_789768;NP_789766	NM_176797;NM_004154;NM_176798;NM_176796	ENSP00000377215;ENSP00000309771;ENSP00000377217;ENSP00000377216	candidate	0	0	0	Vertebrates	0	1	Cellular processes,Signal transduction	48	chr11	73007564	73008547	WES	acute myeloid leukemia
286530	P2RY8	purinergic receptor P2Y, G-protein coupled, 8	Xp22.33; Yp11.3	06671	15524	300525	NP_835230	NM_178129	ENSP00000370697	known	1	0	1	Vertebrates	1	0	Signal transduction	-1	chrX	1584375	1585451	CGC,HTMS,WES	leukemia,breast,lung,ovarian,pancreas,prostate,lymphoma
26986	PABPC1	poly(A) binding protein, cytoplasmic 1	8q22.2-q23	05247	8554	604679	NP_002559	NM_002568	ENSP00000313007	candidate	0	0	4	Last Universal Common Ancestor	155	3	DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	109	chr8	101716529	101733811	WES	lymphoma
5042	PABPC3	poly(A) binding protein, cytoplasmic 3	13q12-q13	05248	8556	604680	NP_112241	NM_030979	-	candidate	0	0	2	Last Universal Common Ancestor	8	0	DNA/RNA metabolism and transcription,Regulation of transcription	109	chr13	25670337	25672229	WGS	lymphoma
5049	PAFAH1B2	platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)	11q23	03940	8575	602508	NP_002563;NP_001171677;NP_001171676;NP_001171675	NM_002572;NM_001184748;NM_001184747;NM_001184746	ENSP00000434951;ENSP00000388742;ENSP00000435289	known	1	0	2	Last Universal Common Ancestor	31	3	Cellular metabolism,Development,Multicellular activities	43	chr11	117023164	117038412	CGC	lymphoma
5058	PAK1	p21 protein (Cdc42/Rac)-activated kinase 1	11q13-q14	03995	8590	602590	NP_002567;NP_001122092	NM_002576;NM_001128620	ENSP00000348696	known	0	0	0	Last Universal Common Ancestor	113	6	Cell cycle,Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction	10	chr11	77034347	77103565	CGC,Amplified	
5063	PAK3	p21 protein (Cdc42/Rac)-activated kinase 3	Xq23	02142	8592	300142	NP_001121639;NP_002569;NP_001121644;NP_001121640;NP_001121645;NP_001121638	NM_001128167;NM_002578;NM_001128172;NM_001128168;NM_001128173;NM_001128166	ENSP00000410853;ENSP00000401982;ENSP00000353864;ENSP00000389172;ENSP00000262836;ENSP00000361077	candidate	0	0	0	Last Universal Common Ancestor	19	1	Cellular metabolism,Cellular processes	60	chrX	110366332	110463672	HTMS	lung
79728	PALB2	partner and localizer of BRCA2	16p12.2	07966	26144	610355	NP_078951	NM_024675	ENSP00000261584	known	0	1	0	Metazoans	14	0	-1	7	chr16	23614783	23652478	CGC,WGS	breast
60676	PAPPA2	pappalysin 2	1q23-q25	10156	14615	-	NP_068755;NP_064714	NM_021936;NM_020318	ENSP00000356633	candidate	0	0	0	Last Universal Common Ancestor	11	0	Cell cycle,Cellular metabolism,Regulation of intracellular processes and metabolism	82	chr1	176525459	176811587	WGS	lung
164091	PAQR7	progestin and adipoQ receptor family member VII	1p36.11	09692	23146	607779	NP_848509	NM_178422	ENSP00000363414	candidate	0	0	0	Last Universal Common Ancestor	2	0	-1	-1	chr1	26189293	26190330	WGS	breast
83666	PARP9	poly (ADP-ribose) polymerase family, member 9	3q21	10686	24118	612065	NP_113646;NP_001139576;NP_001139575;NP_001139577;NP_001139574;NP_001139578	NM_031458;NM_001146104;NM_001146103;NM_001146105;NM_001146102;NM_001146106	ENSP00000419506;ENSP00000419001;ENSP00000418894;ENSP00000353512	candidate	0	0	0	Last Universal Common Ancestor	5	4	Cell motility and interactions	-1	chr3	122247214	122277323	HTMS	breast,lung,ovarian,pancreas,prostate
55742	PARVA	parvin, alpha	11p15.3	16283	14652	608120	NP_060692	NM_018222	-	candidate	0	0	0	Metazoans	15	2	-1	75	chr11	12399075	12549469	WGS	breast
139135	PASD1	PAS domain containing 1	Xq28	06613	20686	-	NP_775764	NM_173493	ENSP00000359382	candidate	0	0	0	Eukaryotes	0	0	Signal transduction	-1	chrX	150773117	150844612	WES	lymphoma
23598	PATZ1	POZ (BTB) and AT hook containing zinc finger 1	22q12.2	05522	13071	605165	NP_114441;NP_114439;NP_114440;NP_055138	NM_032052;NM_032050;NM_032051;NM_014323	ENSP00000266269;ENSP00000337520;ENSP00000215919;ENSP00000384173	known	1	0	0	Last Universal Common Ancestor	0	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	97	chr22	31722880	31741588	CGC,WGS	sarcoma,lung
5077	PAX3	paired box 3	2q35-q37|2q35	09421	8617	606597	NP_852125;NP_852123;NP_852124;NP_000429;NP_039230;NP_001120838;NP_852122;NP_852126	NM_181460;NM_181458;NM_181459;NM_000438;NM_013942;NM_001127366;NM_181457;NM_181461	ENSP00000386817;ENSP00000258387;ENSP00000386750;ENSP00000343052;ENSP00000375921;ENSP00000342092	known	1	0	0	Opisthokonts	27	5	Cell cycle,Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription	27	chr2	223065896	223163334	CGC	sarcoma
5079	PAX5	paired box 5	9p13	01334	8619	167414	NP_057953	NM_016734	-	known	1	0	0	Metazoans	16	0	Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription	11	chr9	36840560	37034028	CGC,HTMS	leukemia,non-hodgkin lymphoma,breast,lung,ovarian,pancreas,prostate
5081	PAX7	paired box 7	1p36.13	01331	8621	167410	NP_001128726;NP_002575;NP_039236	NM_001135254;NM_002584;NM_013945	ENSP00000403389;ENSP00000364524	known	1	0	0	Opisthokonts	11	1	Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription	8	chr1	18958098	19062530	CGC	sarcoma
7849	PAX8	paired box 8	2q13	01335	8622	167415	NP_039247;NP_039246;NP_003457;NP_054698	NM_013953;NM_013951;NM_013952;NM_003466;NM_013992	ENSP00000395498;ENSP00000314750;ENSP00000263335;ENSP00000380768	known	1	0	0	Metazoans	19	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	109	chr2	113976113	114004497	CGC	thyroid
5083	PAX9	paired box 9	14q13.3	01336	8623	167416	NP_006185	NM_006194	ENSP00000384817	known	0	0	0	Metazoans	11	0	Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription	42	chr14	37132101	37145654	CGC,Amplified	
55193	PBRM1	polybromo 1	3p21	-	30064	606083	NP_060635;NP_851385;NP_060783	NM_181041;NM_018165;NM_181042;NM_018313	ENSP00000349213	known	0	1	0	Eukaryotes	35	4	Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	98	chr3	52582082	52713727	CGC,WES,WGS	breast,kidney,pancreas,prostate
5087	PBX1	pre-B-cell leukemia homeobox 1	1q23	08889	8632	176310	NP_001191890;NP_002576;NP_001191892	NM_001204961;NM_002585;NM_001204963	ENSP00000405890	known	1	0	2	Eukaryotes	33	4	Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription	94	chr1	164529060	164815910	CGC	leukemia,myoepithelioma
27328	PCDH11X	protocadherin 11 X-linked	Xq21.3	02215	8656	300246	NP_055337;NP_116751;NP_001161834;NP_001161832;NP_116749;NP_116750;NP_001161833;NP_001161835	NM_014522;NM_032969;NM_001168362;NM_001168360;NM_032967;NM_032968;NM_001168361;NM_001168363	ENSP00000355040;ENSP00000378746;ENSP00000362186;ENSP00000362189	candidate	0	0	1	Eukaryotes	1	0	Cell motility and interactions	32	chrX	91090504	91873936	WES	chronic lymphocytic leukemia,colorectal
65217	PCDH15	protocadherin-related 15	10q21.1	05698	14674	605514	NP_001136244;NP_001136242;NP_001136235;NP_001136236;NP_149045;NP_001136243;NP_001136241;NP_001136245;NP_001136240;NP_001136238;NP_001136237;NP_001136239	NM_001142772;NM_001142770;NM_001142763;NM_001142764;NM_033056;NM_001142771;NM_001142769;NM_001142773;NM_001142768;NM_001142766;NM_001142765;NM_001142767	ENSP00000354950;ENSP00000412628;ENSP00000378818;ENSP00000378820;ENSP00000378832;ENSP00000378826;ENSP00000363076;ENSP00000378821;ENSP00000322604	candidate	0	0	0	Eukaryotes	0	0	Cell motility and interactions,Cell response to stimuli,Multicellular activities,Regulation of intracellular processes and metabolism	-1	chr10	55581621	56424022	WES,WGS	head and neck squamous cell carcinoma,pancreas,prostate
27253	PCDH17	protocadherin 17	13q21.1	-	14267	611760	NP_001035519	NM_014459;NM_001040429	ENSP00000367151	candidate	0	0	0	Eukaryotes	4	0	Cell motility and interactions	83	chr13	58206681	58299425	WES	pancreas
54510	PCDH18	protocadherin 18	4q31	12205	14268	608287	NP_061908	NM_019035	ENSP00000355082	candidate	0	0	0	Eukaryotes	2	0	Cell motility and interactions,Development	-1	chr4	138442186	138453242	WES,WGS	pancreas,lymphoma
64881	PCDH20	protocadherin 20	13q21	-	14257	614449	NP_073754	NM_022843	ENSP00000387250	candidate	0	0	0	Eukaryotes	1	0	Cell motility and interactions	-1	chr13	61985379	61989291	WGS	glioblastoma
5099	PCDH7	protocadherin 7	4p15	04288	8659	602988	NP_002580;NP_115832;NP_001166994;NP_115833	NM_002589;NM_032456;NM_001173523;NM_032457	ENSP00000355243	candidate	0	0	0	Eukaryotes	6	3	Cell motility and interactions	73	chr4	30723045	31144468	WGS	liver
56136	PCDHA13	protocadherin alpha 13	5q31	07554	8667	606319	NP_114071;NP_061727	NM_031865;NM_018904	ENSP00000289272	candidate	0	0	6	Eukaryotes	41	0	Cell motility and interactions	17	chr5	140261854	140389519	WES,WGS	cholangiocarcinoma,liver
56146	PCDHA2	protocadherin alpha 2	5q31	07320	8668	606308	NP_061728;NP_113683	NM_031496;NM_018905;NM_031495	ENSP00000431748;ENSP00000367372	candidate	0	0	-1	Eukaryotes	18	0	Cell motility and interactions,Development	27	-	0	0	WGS	lymphoma
56144	PCDHA4	protocadherin alpha 4	5q31	07322	8670	606310	NP_113688;NP_061730	NM_031500;NM_018907	ENSP00000435300;ENSP00000349344	candidate	0	0	-1	Eukaryotes	26	2	Cell motility and interactions,Development	17	-	0	0	WGS	lymphoma
56142	PCDHA6	protocadherin alpha 6	5q31	07324	8672	606312	NP_114037;NP_114036;NP_061732	NM_031849;NM_031848;NM_018909	ENSP00000433378	candidate	0	0	9	Eukaryotes	9	1	Cell motility and interactions,Development	25	chr5	140207677	140389519	WGS	acute myeloid leukemia
9752	PCDHA9	protocadherin alpha 9	5q31	07327	8675	606315	NP_054724;NP_114063	NM_014005;NM_031857	ENSP00000367362;ENSP00000436042	candidate	0	0	7	Eukaryotes	7	0	Cell motility and interactions	55	chr5	140228081	140389519	WES	colorectal
56121	PCDHB15	protocadherin beta 15	5q31	06959	8686	606341	NP_061758	NM_018935	ENSP00000231173	candidate	0	0	13	Eukaryotes	0	1	Cell motility and interactions,Development	-1	chr5	140625147	140627507	WES	breast
56130	PCDHB6	protocadherin beta 6	5q31	07561	8691	606332	NP_061762	NM_018939	ENSP00000231136	candidate	0	0	13	Eukaryotes	0	0	Cell motility and interactions,Development,Multicellular activities	27	chr5	140529839	140532220	WES	lymphoma
56128	PCDHB8	protocadherin beta 8	5q31	07563	8693	606334	NP_061993	NM_019120	ENSP00000239444	candidate	0	0	10	Eukaryotes	3	3	Cell motility and interactions	9	chr5	140557616	140560018	WES	melanoma
56097	PCDHGC5	protocadherin gamma subfamily C, 5	5q31	07318	8718	606306	NP_061752;NP_115783	NM_018929;NM_032407	ENSP00000252087	candidate	0	0	0	Eukaryotes	8	1	Cell motility and interactions	36	chr5	140868808	140890737	WES	chronic lymphocytic leukemia
27445	PCLO	piccolo (presynaptic cytomatrix protein)	7q11.23-q21.3	16078	13406	604918	NP_055325;NP_149015	NM_014510;NM_033026	ENSP00000388393	candidate	0	0	0	Last Universal Common Ancestor	4	0	Cellular processes,Multicellular activities,Signal transduction	72	chr7	82387894	82791908	WES	chronic lymphocytic leukemia,lymphoma
5108	PCM1	pericentriolar material 1	8p22-p21.3	02624	8727	600299	NP_006188	NM_006197	-	known	1	0	0	Eukaryotes	40	0	Cellular processes,Development	99	chr8	17793120	17883166	CGC	leukemia,myeloma,thyroid
115294	PCMTD1	protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1	8q11.23	08313	30483	-	NP_443169	NM_052937	ENSP00000353739	candidate	0	0	0	Last Universal Common Ancestor	4	1	Cellular metabolism,Cellular processes	-1	chr8	52732914	52773711	WGS	lymphoma
5046	PCSK6	proprotein convertase subtilisin/kexin type 6	15q26.3	01329	8569	167405	NP_612198;NP_612197;NP_612195;NP_612192;NP_002561;NP_612196;NP_612193;NP_612194	NM_138325;NM_138324;NM_138322;NM_138319;NM_002570;NM_138323;NM_138320;NM_138321	ENSP00000305056;ENSP00000351193;ENSP00000381243;ENSP00000344410	candidate	0	0	0	Last Universal Common Ancestor	7	0	Cell cycle,Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction	72	chr15	101853355	102029686	WES	pancreas
9159	PCSK7	proprotein convertase subtilisin/kexin type 7	11q23-q24	05339	8748	604872	NP_004707	NM_004716	-	known	1	0	0	Last Universal Common Ancestor	0	0	Cellular metabolism,Cellular processes	50	chr11	117076716	117100560	CGC	lymphoma
22984	PDCD11	programmed cell death 11	10q24.33	18752	13408	612333	NP_055791	NM_014976	ENSP00000358812	candidate	0	0	0	Last Universal Common Ancestor	5	2	DNA/RNA metabolism and transcription,Regulation of transcription	99	chr10	105158184	105205303	WES,WGS	breast,prostate
80380	PDCD1LG2	programmed cell death 1 ligand 2	9p24.2	16147	18731	605723	NP_079515	NM_025239	ENSP00000380855	known	1	0	0	Vertebrates	1	0	-1	2	chr9	5522547	5563211	CGC	lymphoma
10016	PDCD6	programmed cell death 6	5p15.33	03035	8765	601057	NP_037364	NM_013232	ENSP00000423815;ENSP00000264933	candidate	0	0	0	Vertebrates	47	0	Cell cycle,Cell response to stimuli,Development,Regulation of intracellular processes and metabolism	108	chr5	271836	314627	WES	pancreas
5153	PDE1B	phosphodiesterase 1B, calmodulin-dependent	12q13	01388	8775	171891	NP_001159447;NP_000915	NM_001165975;NM_000924	ENSP00000243052	candidate	0	0	0	Eukaryotes	2	0	Cell cycle,Signal transduction	7	chr12	54943657	54971109	WGS	lung
5142	PDE4B	phosphodiesterase 4B, cAMP-specific	1p31	02528	8781	600127	NP_001032416;NP_001032418;NP_002591;NP_001032417	NM_001037339;NM_001037341;NM_002600;NM_001037340	ENSP00000360084;ENSP00000392947;ENSP00000332116	candidate	0	0	0	Eukaryotes	7	0	Signal transduction	88	chr1	66378998	66838358	WGS	liver
9659	PDE4DIP	phosphodiesterase 4D interacting protein	1q12	10482	15580	608117	NP_001185763;NP_071754;NP_001185761;NP_055459;NP_001002810;NP_001182189;NP_001002811;NP_001182190;NP_001002812	NM_001198834;NM_022359;NM_001198832;NM_014644;NM_001002810;NM_001195260;NM_001002811;NM_001195261;NM_001002812	ENSP00000358353;ENSP00000316434;ENSP00000358355;ENSP00000327209;ENSP00000358363;ENSP00000358360;ENSP00000358354	known	1	0	0	Metazoans	42	0	Cellular processes	70	chr1	144852357	144994731	CGC,WGS	myeloma,chronic lymphocytic leukemia
5155	PDGFB	platelet-derived growth factor beta polypeptide	22q12.3-q13.1|22q13.1	01815	8800	190040	NP_002599;NP_148937	NM_002608;NM_033016	ENSP00000330382	known	1	0	0	Vertebrates	15	2	Cell cycle,Cell motility and interactions,Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Immune system response,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	76	chr22	39621731	39639968	CGC	sarcoma
56034	PDGFC	platelet derived growth factor C	4q32	10529	8801	608452	NP_057289	NM_016205;NR_036641	-	candidate	0	0	0	Eukaryotes	29	7	Development	90	chr4	157684245	157892055	WES,WGS	lymphoma,lung
5156	PDGFRA	platelet-derived growth factor receptor, alpha polypeptide	4q12	01429	8803	173490	NP_006197	NM_006206	ENSP00000257290	known	1	0	0	Last Universal Common Ancestor	36	2	Cell cycle,Cell motility and interactions,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	84	chr4	55124936	55161436	CGC,HTMS	gastric,glioblastoma,idiopathic hypereosinophilic syndrome,lung
5159	PDGFRB	platelet-derived growth factor receptor, beta polypeptide	5q33.1	01423	8804	173410	NP_002600	NM_002609	ENSP00000261799	known	1	0	0	Last Universal Common Ancestor	102	1	Cell cycle,Cell motility and interactions,Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction	68	chr5	149495329	149515445	CGC	leukemia,myeloma
9601	PDIA4	protein disulfide isomerase family A, member 4	7q35	06501	30167	-	NP_004902	NM_004911	ENSP00000286091	candidate	0	0	0	Last Universal Common Ancestor	25	1	Cellular processes,Regulation of intracellular processes and metabolism	106	chr7	148700889	148725500	HTMS	breast,lung,ovarian,pancreas,prostate
5173	PDYN	prodynorphin	20p13	08838	8820	131340	NP_077722;NP_001177829;NP_001177821;NP_001177827;NP_001177828	NM_024411;NM_001190900;NM_001190892;NM_001190898;NM_001190899	ENSP00000440185;ENSP00000442259;ENSP00000217305	candidate	0	0	0	Vertebrates	2	0	Multicellular activities,Signal transduction	20	chr20	1960972	1963730	WES	lung
23024	PDZRN3	PDZ domain containing ring finger 3	3p13	15115	17704	609729	NP_055824	NM_015009	ENSP00000263666	candidate	0	0	0	Metazoans	0	0	-1	47	chr3	73432519	73673976	WES	pancreas
375033	PEAR1	platelet endothelial aggregation receptor 1	1q23.1	-	33631	610278	NP_001073940	NM_207369;NM_001080471	ENSP00000292357	candidate	0	0	0	Eukaryotes	0	0	-1	-1	chr1	156873719	156884587	WES	pancreas
5178	PEG3	paternally expressed 3	19q13.4	03285	8826	601483	NP_001139659;NP_006201;NP_001139656;NP_001139658;NP_001139657	NM_001146187;NM_006210;NM_001146184;NM_001146186;NM_001146185	ENSP00000403051;ENSP00000326581	candidate	0	0	0	Last Universal Common Ancestor	12	1	Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	87	chr19	57325046	57336023	WES	cholangiocarcinoma
5187	PER1	period homolog 1 (Drosophila)	17p13.1	03774	8845	602260	NP_002607	NM_002616	ENSP00000314420	known	1	0	0	Eukaryotes	18	1	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	105	chr17	8044389	8054024	CGC	leukemia
5214	PFKP	phosphofructokinase, platelet	10p15.3-p15.2	01384	8878	171840	NP_001229268;NP_002618	NM_001242339;NM_002627	ENSP00000370465;ENSP00000370517	candidate	0	0	0	Last Universal Common Ancestor	35	4	Cellular metabolism	96	chr10	3109788	3178768	WGS	medulloblastoma
27315	PGAP2	post-GPI attachment to proteins 2	11p15.5	17016	17893	-	NP_001243168;NP_055304;NP_001138910;NP_001243164;NP_001243169;NP_001243167;NP_001243165;NP_001243166	NR_027016;NR_045925;NM_001256239;NM_014489;NM_001145438;NM_001256235;NM_001256240;NR_045927;NM_001256238;NR_045929;NM_001256236;NR_027014;NR_027017;NR_027018;NR_045926;NM_001256237;NR_027015;NR_045923	ENSP00000300730;ENSP00000431851;ENSP00000278243	candidate	0	0	0	Eukaryotes	0	0	Cellular metabolism,Cellular processes	74	chr11	3819074	3846685	WES	lymphoma
1912	PHC2	polyhomeotic homolog 2 (Drosophila)	1p34.3	10340	3183	602979	NP_004418;NP_932157	NM_004427;NM_198040	ENSP00000362517;ENSP00000257118	candidate	0	0	0	Eukaryotes	58	9	-1	107	chr1	33790469	33841140	WES	chronic lymphocytic leukemia
23469	PHF3	PHD finger protein 3	6q12	08477	8921	607789	NP_055968	NM_015153	ENSP00000377048	candidate	0	0	0	Eukaryotes	4	4	Cellular metabolism,DNA/RNA metabolism and transcription	92	chr6	64356457	64423601	WES	pancreas
84295	PHF6	PHD finger protein 6	Xq26.3	02330	18145	300414	NP_001015877;NP_115711;NP_115834	NM_001015877;NM_032335;NM_032458	ENSP00000359839;ENSP00000359836;ENSP00000329097	known	0	1	0	Eukaryotes	8	6	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	-1	chrX	133511648	133559357	CGC	leukemia
55023	PHIP	pleckstrin homology domain interacting protein	6q14	10152	15673	612870	NP_060404	NM_017934	-	candidate	0	0	0	Last Universal Common Ancestor	37	3	Signal transduction	67	chr6	79650413	79787785	WES	glioblastoma
8929	PHOX2B	paired-like homeobox 2b	4p12	09157	9143	603851	NP_003915	NM_003924	ENSP00000226382	known	0	1	0	Eukaryotes	1	0	Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription	39	chr4	41747827	41750627	CGC	neuroblastoma
5297	PI4KA	phosphatidylinositol 4-kinase, catalytic, alpha	22q11.21	08972	8983	600286	NP_002641;NP_477352	NM_002650;NM_058004	ENSP00000402981;ENSP00000255882	candidate	0	0	0	Eukaryotes	17	0	Cellular metabolism,Cellular processes,Multicellular activities,Signal transduction	102	chr22	21062338	21213013	HTMS	sarcoma
8301	PICALM	phosphatidylinositol binding clathrin assembly protein	11q14	04320	15514	603025	NP_009097;NP_001193875;NP_001008660;NP_001193876	NM_007166;NM_001206946;NM_001008660;NM_001206947	ENSP00000436958;ENSP00000433846	known	1	0	0	Eukaryotes	3	8	Cellular processes	105	chr11	85685751	85779822	CGC	leukemia
55022	PID1	phosphotyrosine interaction domain containing 1	2q36.3	07944	26084	612930	NP_060403;NP_001094288	NM_017933;NM_001100818	ENSP00000375908;ENSP00000375907	candidate	0	0	0	Metazoans	2	0	-1	85	chr2	229890351	230020680	WGS	breast
118788	PIK3AP1	phosphoinositide-3-kinase adaptor protein 1	10q24.1	06401	30034	607942	NP_689522	NM_152309	ENSP00000339826	candidate	0	0	0	Metazoans	8	0	-1	-1	chr10	98355337	98469741	WES	head and neck squamous cell carcinoma
5288	PIK3C2G	phosphoinositide-3-kinase, class 2, gamma polypeptide	12p12	16416	8973	609001	NP_004561	NM_004570	ENSP00000404845	candidate	0	0	0	Eukaryotes	1	0	Cellular metabolism,Cellular processes,Signal transduction	31	chr12	18435016	18800959	HTMS	breast,lung,ovarian,pancreas,prostate
5290	PIK3CA	phosphoinositide-3-kinase, catalytic, alpha polypeptide	3q26.3	01382	8975	171834	NP_006209	NM_006218	-	known	1	0	0	Eukaryotes	65	2	Cellular metabolism,Cellular processes,Signal transduction	36	chr3	178916614	178952149	CGC,HTMS,WES,WGS,Amplified	breast,colorectal,gastric,glioblastoma,lung,ovarian,pancreas,prostate,sarcoma,colorectal (non-hypermutated),endometrium,head and neck squamous cell carcinoma,oligodendroglioma,medulloblastoma
5294	PIK3CG	phosphoinositide-3-kinase, catalytic, gamma polypeptide	7q22.3	03135	8978	601232	NP_002640	NM_002649	ENSP00000352121	candidate	0	0	0	Eukaryotes	37	2	Cell cycle,Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction	2	chr7	106508007	106545829	HTMS	breast,lung,ovarian,pancreas,prostate
5295	PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	5q13.1	01381	8979	171833	NP_001229395;NP_852556;NP_852664;NP_852665	NM_001242466;NM_181504;NM_181523;NM_181524	ENSP00000428056	known	0	1	0	Metazoans	310	6	Cellular metabolism,Cellular processes,Signal transduction	99	chr5	67522504	67593426	CGC,HTMS,WES	colorectal,glioblastoma,ovarian,breast,lung,pancreas,prostate,oligodendroglioma
5296	PIK3R2	phosphoinositide-3-kinase, regulatory subunit 2 (beta)	19q13.2-q13.4	04404	8980	603157	NP_005018	NM_005027	ENSP00000222254	candidate	0	0	0	Metazoans	115	3	Cell cycle,Development,Regulation of intracellular processes and metabolism,Signal transduction	90	chr19	18266690	18280101	WGS	chronic lymphocytic leukemia
5292	PIM1	pim-1 oncogene	6p21.2	01292	8986	164960	NP_002639;NP_001230115	NM_002648;NM_001243186	ENSP00000362608	known	1	0	0	Last Universal Common Ancestor	36	9	Cell cycle,Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism	102	chr6	37138082	37141864	CGC,WES	non-hodgkin lymphoma,lymphoma
10343	PKDREJ	polycystic kidney disease (polycystin) and REJ homolog (sperm receptor for egg jelly homolog, sea urchin)	22q13.31	05239	9015	604670	NP_006062	NM_006071	ENSP00000253255	candidate	0	0	0	Eukaryotes	7	0	Cellular processes,Development,Signal transduction	2	chr22	46652461	46659219	WGS	breast
5314	PKHD1	polycystic kidney and hepatic disease 1 (autosomal recessive)	6p12.2	05987	9016	606702	NP_619639;NP_733842	NM_138694;NM_170724	ENSP00000360158;ENSP00000341097	candidate	0	0	0	Last Universal Common Ancestor	1	0	Cell motility and interactions,Regulation of intracellular processes and metabolism	-1	chr6	51483882	51949731	HTMS,WES	breast,lung,ovarian,pancreas,prostate,gastric,glioblastoma
93035	PKHD1L1	polycystic kidney and hepatic disease 1 (autosomal recessive)-like 1	8q23	09703	20313	607843	NP_803875	NM_177531	ENSP00000367655	candidate	0	0	0	Last Universal Common Ancestor	0	1	-1	-1	chr8	110374810	110539248	WES	head and neck squamous cell carcinoma
5585	PKN1	protein kinase N1	19p13.12	03019	9405	601032	NP_998725;NP_002732	NM_213560;NM_002741	ENSP00000242783;ENSP00000343325	candidate	0	0	0	Last Universal Common Ancestor	10	1	Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction	36	chr19	14551103	14582593	WGS	melanoma
5316	PKNOX1	PBX/knotted 1 homeobox 1	21q22.3	03653	9022	602100	NP_004562	NM_004571	ENSP00000291547	candidate	0	0	0	Eukaryotes	14	1	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	40	chr21	44424492	44450208	WES	colorectal
8502	PKP4	plakophilin 4	2q24.1	05043	9026	604276	NP_001005476;NP_003619	NM_001005476;NM_003628	ENSP00000374409	candidate	0	0	0	Eukaryotes	22	2	-1	86	chr2	159389697	159537186	WES	head and neck squamous cell carcinoma
8399	PLA2G10	phospholipase A2, group X	16p13.1-p12	04674	9029	603603	NP_003552	NM_003561	ENSP00000393847	known	0	0	0	Metazoans	3	1	Cellular metabolism	39	chr16	14766467	14784503	CGC,Amplified	
255189	PLA2G4F	phospholipase A2, group IVF	15q15.1	17326	27396	-	NP_998765	NM_213600;NR_033151	ENSP00000371833	candidate	0	0	0	Eukaryotes	1	0	Cellular metabolism	-1	chr15	42434185	42448747	WGS	lymphoma
5324	PLAG1	pleiomorphic adenoma gene 1	8q12	04321	9045	603026	NP_001108107;NP_001108106;NP_002646	NM_001114635;NM_001114634;NM_002655	ENSP00000325546	known	1	0	0	Last Universal Common Ancestor	2	23	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	19	chr8	57078805	57080828	CGC	salivary
151056	PLB1	phospholipase B1	2p23.2	15141	30041	610179	NP_001164056;NP_694566	NM_001170585;NM_153021	ENSP00000416440;ENSP00000330442	candidate	0	0	0	Eukaryotes	1	0	Cellular metabolism	-1	chr2	28718982	28865924	WES	colorectal
5332	PLCB4	phospholipase C, beta 4	20p12	02885	9059	600810	NP_001166117;NP_877949;NP_000924	NM_001172646;NM_182797;NM_000933	ENSP00000367762;ENSP00000367734;ENSP00000278655	candidate	0	0	0	Eukaryotes	2	4	Cellular metabolism,Signal transduction	45	chr20	9288462	9459653	WES,WGS	melanoma
5336	PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific)	16q24.1	02570	9066	600220	NP_002652	NM_002661	ENSP00000352336	candidate	0	0	0	Eukaryotes	8	1	Cellular metabolism,Signal transduction	99	chr16	81819595	81991600	WES	colorectal
9651	PLCH2	phospholipase C, eta 2	1p36.32	-	29037	612836	NP_055453	NM_014638	ENSP00000367747	candidate	0	0	0	Eukaryotes	1	1	Cellular metabolism,Signal transduction	25	chr1	2408028	2436649	WGS	melanoma
5338	PLD2	phospholipase D2	17p13.1	03857	9068	602384	NP_002654;NP_001230037	NM_002663;NM_001243108	ENSP00000459571;ENSP00000263088	candidate	0	0	0	Last Universal Common Ancestor	38	0	Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction	58	chr17	4711068	4726156	WES	breast
5339	PLEC	plectin	8q24	03180	9069	601282	NP_958782;NP_958786;NP_000436;NP_958784;NP_958785;NP_958780;NP_958783;NP_958781	NM_201380;NM_201384;NM_000445;NM_201382;NM_201383;NM_201378;NM_201381;NM_201379	ENSP00000388180;ENSP00000348702;ENSP00000347044;ENSP00000323856;ENSP00000381756;ENSP00000346602;ENSP00000350277;ENSP00000344848	candidate	0	0	0	Eukaryotes	53	8	-1	70	chr8	144990348	145024874	WGS	lymphoma
84725	PLEKHA8	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8	7p21-p11.2	10555	30037	608639	NP_116028;NP_001183955;NP_001183956	NM_032639;NM_001197026;NM_001197027	ENSP00000258679	candidate	0	0	1	Eukaryotes	4	2	Cellular processes	0	chr7	30068379	30118400	WES	breast
153478	PLEKHG4B	pleckstrin homology domain containing, family G (with RhoGef domain) member 4B	5p15.33	13900	29399	-	NP_443141	NM_052909	-	candidate	0	0	0	Metazoans	1	0	Signal transduction	-1	chr5	140423	182435	WGS	lymphoma
57449	PLEKHG5	pleckstrin homology domain containing, family G (with RhoGef domain) member 5	1p36.31	11104	29105	611101	NP_001036129;NP_001036128;NP_001036130;NP_941374;NP_065682	NM_001042664;NM_001042663;NM_001042665;NM_198681;NM_020631	ENSP00000344570;ENSP00000383704;ENSP00000366977	candidate	0	0	0	Metazoans	21	0	Regulation of intracellular processes and metabolism,Signal transduction	-1	chr1	6527878	6579571	WGS	liver
57088	PLSCR4	phospholipid scramblase 4	3q24	07401	16497	607612	NP_001121778;NP_065086;NP_001170775;NP_001121776;NP_001121777	NR_033438;NM_001128306;NR_033439;NM_020353;NM_001177304;NM_001128304;NM_001128305	ENSP00000372561;ENSP00000415605;ENSP00000347038	candidate	0	0	0	Eukaryotes	16	8	Cellular processes,Multicellular activities	87	chr3	145912201	145938713	WES	lung
5371	PML	promyelocytic leukemia	15q22	00023	9113	102578	NP_150250;NP_002666;NP_150253;NP_150252;NP_150243;NP_150247;NP_150249;NP_150242;NP_150241	NM_033247;NM_002675;NM_033250;NM_033249;NM_033240;NM_033244;NM_033246;NM_033239;NM_033238	ENSP00000378567;ENSP00000268058;ENSP00000268059;ENSP00000395576;ENSP00000394642;ENSP00000353004;ENSP00000378564;ENSP00000457023;ENSP00000315434	known	1	0	0	Eukaryotes	38	1	Cell cycle,Cell response to stimuli,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	91	chr15	74287154	74337346	CGC	leukemia
5378	PMS1	PMS1 postmeiotic segregation increased 1 (S. cerevisiae)	2q31-q33|2q31.1	02597	9121	600258	NP_001121615;NP_001121616;NP_000525	NM_001128143;NM_001128144;NM_000534	ENSP00000406490;ENSP00000387125;ENSP00000401064	known	0	1	0	Last Universal Common Ancestor	49	2	Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	94	chr2	190656536	190742159	CGC,WES	lymphoma
5395	PMS2	PMS2 postmeiotic segregation increased 2 (S. cerevisiae)	7p22.2	02598	9122	600259	NP_000526	NR_003085;NM_000535	ENSP00000265849	known	0	1	0	Last Universal Common Ancestor	45	0	Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism	8	chr7	6013033	6045667	CGC	
5387	PMS2P3	postmeiotic segregation increased 2 pseudogene 3	7q11.23	17866	9128	-	-	NM_005395;NM_001003686;NR_028059	-	candidate	0	0	-1	-	0	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	102	-	0	0	WES	gastric
5408	PNLIPRP2	pancreatic lipase-related protein 2	10q25.3	05110	9157	604423	NP_005387	NM_005396	ENSP00000424858	candidate	0	0	0	Primates	0	2	Cell response to stimuli,Cellular metabolism	25	chr10	118380818	118404605	WGS	glioblastoma
375775	PNPLA7	patatin-like phospholipase domain containing 7	9q34.3	12933	24768	612122	NP_001092007;NP_689499	NM_001098537;NM_152286	ENSP00000384610;ENSP00000277531	candidate	0	0	0	Last Universal Common Ancestor	0	0	-1	-1	chr9	140354848	140442114	WES	chronic lymphocytic leukemia
10957	PNRC1	proline-rich nuclear receptor coactivator 1	6q15	08412	17278	606714	NP_006804	NM_006813	ENSP00000336931	candidate	0	0	0	Metazoans	15	2	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	107	chr6	89790614	89793912	WES,WGS	myeloma
134359	POC5	POC5 centriolar protein homolog (Chlamydomonas)	5q13.3	08188	26658	-	NP_001092741;NP_689621	NM_001099271;NM_152408	ENSP00000410216;ENSP00000399481	candidate	0	0	0	Eukaryotes	1	0	-1	-1	chr5	74970263	75008762	WGS	lung
79983	POF1B	premature ovarian failure, 1B	Xq21.2	06679	13711	300603	NP_079197	NM_024921	ENSP00000262753	candidate	0	0	0	Vertebrates	5	0	-1	18	chrX	84537209	84634459	WES	chronic lymphocytic leukemia
51426	POLK	polymerase (DNA directed) kappa	5q13	09291	9183	605650	NP_057302	NM_016218	-	candidate	0	0	0	Last Universal Common Ancestor	21	2	Cellular metabolism,DNA/RNA metabolism and transcription	-1	chr5	74842848	74893840	WGS	chronic lymphocytic leukemia
11128	POLR3A	polymerase (RNA) III (DNA directed) polypeptide A, 155kDa	10q22-q23	17879	30074	614258	NP_008986	NM_007055	ENSP00000361446	candidate	0	0	0	Last Universal Common Ancestor	2	2	Cellular metabolism,DNA/RNA metabolism and transcription	-1	chr10	79737239	79789165	WGS	prostate
25913	POT1	protection of telomeres 1 homolog (S. pombe)	7q31.33	07572	17284	606478	NP_001036059;NP_056265	NR_003104;NM_001042594;NR_003103;NR_003102;NM_015450	ENSP00000377002;ENSP00000350249	candidate	0	0	0	Eukaryotes	25	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism	77	chr7	124464019	124532434	WES	chronic lymphocytic leukemia
388468	POTEC	POTE ankyrin domain family, member C	18p11.21	-	33894	-	NP_001131143	NM_001137671	-	candidate	0	0	10	Last Universal Common Ancestor	0	0	-1	-1	chr18	14511900	14543145	WES	melanoma
317754	POTED	POTE ankyrin domain family, member D	21q11.2	09612	23822	607549	NP_778146	NM_174981	ENSP00000299443	candidate	0	0	10	Last Universal Common Ancestor	0	0	-1	-1	chr21	14982550	15013884	WGS	melanoma
5450	POU2AF1	POU class 2 associating factor 1	11q23.1	03126	9211	601206	NP_006226	NM_006235	ENSP00000376786	known	1	0	0	Vertebrates	1	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	29	chr11	111224989	111229641	CGC	non-hodgkin lymphoma
5452	POU2F2	POU class 2 homeobox 2	19q13.2	01251	9213	164176	NP_001193955;NP_001234923;NP_001193954;NP_002689	NM_001207026;NM_001247994;NM_001207025;NM_002698	ENSP00000436988	candidate	0	0	0	Metazoans	1	1	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	52	chr19	42595707	42626732	WES	lymphoma
5460	POU5F1	POU class 5 homeobox 1	6p21.31	01252	9221	164177	NP_001167002;NP_976034;NP_002692	NM_001173531;NM_203289;NM_002701	ENSP00000425479;ENSP00000425083	known	1	0	3	Vertebrates	62	1	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	0	chr6	31132381	31138397	CGC	sarcoma
5468	PPARG	peroxisome proliferator-activated receptor gamma	3p25	03288	9236	601487	NP_005028;NP_619726;NP_619725;NP_056953	NM_005037;NM_138712;NM_138711;NM_015869	ENSP00000380210;ENSP00000287820;ENSP00000380207;ENSP00000312472	known	1	0	0	Metazoans	108	8	Cell cycle,Cell response to stimuli,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Immune system response,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	9	chr3	12393092	12475641	CGC	thyroid
8493	PPM1D	protein phosphatase, Mg2+/Mn2+ dependent, 1D	17q23.2	05482	9277	605100	NP_003611	NM_003620	-	known	0	0	0	Last Universal Common Ancestor	10	7	Cell cycle,Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism	65	chr17	58677776	58740910	CGC,Amplified	
22843	PPM1E	protein phosphatase, Mg2+/Mn2+ dependent, 1E	17q22	17888	19322	-	NP_055721	NM_014906	-	candidate	0	0	0	Last Universal Common Ancestor	5	1	Cellular metabolism,Cellular processes	14	chr17	56833359	57058389	WES	breast
151742	PPM1L	protein phosphatase, Mg2+/Mn2+ dependent, 1L	3q26.1	17889	16381	611931	NP_640338	NM_139245	-	candidate	0	0	0	Last Universal Common Ancestor	2	2	Cellular metabolism,Cellular processes	-1	chr3	160474097	160786942	HTMS	breast,lung,ovarian,pancreas,prostate
5506	PPP1R3A	protein phosphatase 1, regulatory subunit 3A	7q31.1	02950	9291	600917	NP_002702	NM_002711	ENSP00000284601	candidate	0	0	0	Last Universal Common Ancestor	1	1	Cellular metabolism	9	chr7	113517781	113559051	HTMS,WES	breast,lung,ovarian,pancreas,prostate
55607	PPP1R9A	protein phosphatase 1, regulatory subunit 9A	7q21.3	-	14946	602468	NP_060120;NP_001159632;NP_001159634;NP_001159633;NP_001159635	NM_017650;NM_001166160;NM_001166162;NM_001166161;NM_001166163	ENSP00000289495;ENSP00000402893;ENSP00000344524	candidate	0	0	0	Opisthokonts	12	3	Development	53	chr7	94539426	94919612	WES,WGS	head and neck squamous cell carcinoma,chronic lymphocytic leukemia
5518	PPP2R1A	protein phosphatase 2, regulatory subunit A, alpha	19q13.41	16184	9302	605983	NP_055040	NR_033500;NM_014225	-	known	1	0	1	Eukaryotes	100	2	Cell cycle,Cell motility and interactions,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	93	chr19	52693350	52729060	CGC,WES	ovarian,endometrium
5521	PPP2R2B	protein phosphatase 2, regulatory subunit B, beta	5q32	05059	9305	604325	NP_004567;NP_858060;NP_858062;NP_858061;NP_858063;NP_001120853;NP_858064	NM_004576;NM_181674;NM_181676;NM_181675;NM_181677;NM_001127381;NM_181678	ENSP00000349283;ENSP00000377933;ENSP00000336591;ENSP00000421396;ENSP00000377932	candidate	0	0	3	Eukaryotes	207	0	Signal transduction	77	chr5	145969513	146435306	WGS	prostate
5525	PPP2R5A	protein phosphatase 2, regulatory subunit B', alpha	1q32.2-q32.3	03384	9309	601643	NP_006234;NP_001186685	NM_006243;NM_001199756	ENSP00000261461	candidate	0	0	0	Eukaryotes	35	3	Signal transduction	80	chr1	212459453	212534109	WES	lymphoma
9701	PPP6R2	protein phosphatase 6, regulatory subunit 2	22q13.33	11102	19253	610877	NP_055493;NP_001229828;NP_001229829;NP_001229827	NM_014678;NM_001242899;NM_001242900;NM_001242898	ENSP00000379090;ENSP00000352051;ENSP00000379093	candidate	0	0	0	Eukaryotes	12	4	-1	69	chr22	50832338	50882673	WES	lymphoma
51029	PPPDE1	PPPDE peptidase domain containing 1	1q44	15153	24264	-	NP_057160	NM_016076	ENSP00000306528	candidate	0	0	0	Eukaryotes	1	0	-1	100	chr1	244816616	244869088	WGS	breast
5540	PPYR1	pancreatic polypeptide receptor 1	10q11.2	03476	9329	601790	NP_005963	NM_005972	ENSP00000363431	candidate	0	0	0	Metazoans	0	1	Multicellular activities,Signal transduction	11	chr10	47086784	47087908	WGS	glioblastoma
5545	PRB4	proline-rich protein BstNI subfamily 4	12p13.2	01624	9340	180990	NP_002714	NM_002723	ENSP00000412740;ENSP00000279575	candidate	0	0	7	-	1	0	-1	2	chr12	11461176	11463332	WES	head and neck squamous cell carcinoma
9055	PRC1	protein regulator of cytokinesis 1	15q26.1	17899	9341	603484	NP_003972;NP_955446;NP_955445	NM_003981;NM_199414;NM_199413	ENSP00000377793;ENSP00000354618	candidate	0	0	0	Eukaryotes	19	2	Cell cycle,Cellular processes	32	chr15	91510364	91528057	WGS	melanoma
5546	PRCC	papillary renal cell carcinoma (translocation-associated)	1q21.1	01562	9343	179755	NP_005964	NM_005973;NM_199416	ENSP00000271526	known	1	0	0	Eukaryotes	11	0	-1	50	chr1	156737564	156770249	CGC	kidney
639	PRDM1	PR domain containing 1, with ZNF domain	6q21	04572	9346	603423	NP_878911;NP_001189	NM_182907;NM_001198	ENSP00000358092;ENSP00000358085	known	0	1	0	Last Universal Common Ancestor	22	12	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	26	chr6	106534429	106555358	CGC,WES	lymphoma
63976	PRDM16	PR domain containing 16	1p36.23-p33	16122	14000	605557	NP_071397;NP_955533	NM_022114;NM_199454	ENSP00000270722;ENSP00000405253	known	1	0	0	Last Universal Common Ancestor	7	4	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	11	chr1	3102691	3350372	CGC	leukemia,myelodysplasia
7799	PRDM2	PR domain containing 2, with ZNF domain	1p36.21	03120	9347	601196	NP_001129082;NP_001007258;NP_036363;NP_056950	NM_001135610;NM_001007257;NM_012231;NM_015866	ENSP00000411103;ENSP00000365216;ENSP00000235372;ENSP00000312352	candidate	0	0	0	Eukaryotes	10	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	103	chr1	14057492	14143039	WGS	prostate
56979	PRDM9	PR domain containing 9	5p14	17905	13994	609760	NP_064612	NM_020227	ENSP00000296682	candidate	0	0	0	Last Universal Common Ancestor	0	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	1	chr5	23509579	23527879	WES	chronic lymphocytic leukemia,colorectal,head and neck squamous cell carcinoma,lung
80243	PREX2	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2	8q13.2	13135	22950	612139	NP_079146;NP_079446	NM_024870;NM_025170	-	candidate	0	0	0	Eukaryotes	5	1	Signal transduction	36	chr8	68864630	69143610	WES,WGS	pancreas,melanoma
5551	PRF1	perforin 1 (pore forming protein)	10q22	01362	9360	170280	NP_005032;NP_001076585	NM_005041;NM_001083116	ENSP00000398568;ENSP00000316746	known	0	1	0	Metazoans	5	0	Cell cycle,Cell response to stimuli,Cellular processes,Other	75	chr10	72357812	72360658	CGC	
23572	PRG4	p53-responsive gene 4	-	-	-	605160	-	-	-	candidate	0	0	-1	Last Universal Common Ancestor	0	3	-1	-1	-	0	0	WGS	melanoma
5565	PRKAB2	protein kinase, AMP-activated, beta 2 non-catalytic subunit	1q21.1	04117	9379	602741	NP_005390	NM_005399	ENSP00000254101	candidate	0	0	0	Eukaryotes	28	6	Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction	56	chr1	146631147	146643723	HTMS	breast,lung,ovarian,pancreas,prostate
5573	PRKAR1A	protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)	17q23-q24	01786	9388	188830	NP_002725;NP_997637;NP_997636	NM_002734;NM_212472;NM_212471	ENSP00000464977;ENSP00000351410;ENSP00000376475	known	1	1	2	Last Universal Common Ancestor	55	5	Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	108	chr17	66511541	66526587	CGC,HTMS	thyroid,breast,lung,ovarian,pancreas,prostate
5579	PRKCB	protein kinase C, beta	16p11.2	01499	9395	176970	NP_002729;NP_997700	NM_002738;NM_212535	ENSP00000305355;ENSP00000318315	candidate	0	0	1	Last Universal Common Ancestor	2	3	Cellular metabolism,Cellular processes,Signal transduction	100	chr16	23847497	24226134	HTMS	breast,lung,ovarian,pancreas,prostate
5582	PRKCG	protein kinase C, gamma	19q13.4	01502	9402	176980	NP_002730	NM_002739	ENSP00000263431	candidate	0	0	0	Last Universal Common Ancestor	6	1	Cell response to stimuli,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	3	chr19	54385749	54410146	WES	pancreas
5584	PRKCI	protein kinase C, iota	3q26.3	02105	9404	600539	NP_002731	NM_002740	ENSP00000295797	known	0	0	1	Last Universal Common Ancestor	35	1	Cell cycle,Cell motility and interactions,Cellular metabolism,Cellular processes,Development,Signal transduction	103	chr3	169940458	170020912	CGC,WGS,Amplified	prostate
5587	PRKD1	protein kinase D1	14q11	05668	9407	605435	NP_002733	NM_002742	ENSP00000333568	candidate	0	0	0	Last Universal Common Ancestor	7	1	Cellular metabolism,Cellular processes,Signal transduction	68	chr14	30046447	30396718	WES	colorectal
5593	PRKG2	protein kinase, cGMP-dependent, type II	4q13.1-q21.1	09034	9416	601591	NP_006250	NM_006259	ENSP00000264399	candidate	0	0	0	Last Universal Common Ancestor	1	3	Cellular metabolism,Cellular processes,Signal transduction	58	chr4	82010865	82126201	WGS	breast
5613	PRKX	protein kinase, X-linked	Xp22.3	02097	9441	300083	NP_005035	NM_005044	ENSP00000262848	candidate	0	0	2	Last Universal Common Ancestor	4	1	Cellular metabolism,Cellular processes	37	chrX	3530244	3631294	WES	melanoma
5618	PRLR	prolactin receptor	5p13.2	01457	9446	176761	NP_001191244;NP_001191247;NP_000940;NP_001191243;NP_001191245;NP_001191246	NM_001204315;NM_001204318;NM_000949;NM_001204314;NM_001204316;NR_037910;NM_001204317	ENSP00000371432;ENSP00000339213;ENSP00000309008;ENSP00000231423;ENSP00000424841;ENSP00000311613	candidate	0	0	0	Metazoans	5	2	Cell cycle,Cellular metabolism,Cellular processes,Development,Immune system response,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction	44	chr5	35065194	35089722	WES	chronic lymphocytic leukemia
60675	PROK2	prokineticin 2	3p13	08446	18455	607002	NP_068754;NP_001119600	NM_021935;NM_001126128	ENSP00000295618	candidate	0	0	0	Metazoans	0	1	Cell cycle,Cell motility and interactions,Cell response to stimuli,Cellular metabolism,Cellular processes,Development,Immune system response,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction	-1	chr3	71821878	71834203	WGS	melanoma
128674	PROKR2	prokineticin receptor 2	20p12.3	08453	15836	607123	NP_658986	NM_144773	ENSP00000217270	candidate	0	0	1	Metazoans	0	1	Signal transduction	-1	chr20	5282689	5295015	WES	head and neck squamous cell carcinoma
8842	PROM1	prominin 1	4p15.32	05079	9454	604365	NP_006008;NP_001139321;NP_001139320;NP_001139323;NP_001139319;NP_001139322;NP_001139324	NM_006017;NM_001145849;NM_001145848;NM_001145851;NM_001145847;NM_001145850;NM_001145852	ENSP00000427346;ENSP00000426090;ENSP00000438045;ENSP00000443620;ENSP00000415481	candidate	0	0	0	Metazoans	5	1	Cell response to stimuli	64	chr4	15981020	16077529	WES	chronic lymphocytic leukemia
80209	PROSER1	proline and serine rich 1	13q13.3	12616	20291	-	NP_733837;NP_079414	NM_170719;NM_025138	ENSP00000332034	candidate	0	0	0	Last Universal Common Ancestor	2	5	-1	64	chr13	39585505	39611379	WGS	chronic lymphocytic leukemia
8899	PRPF4B	PRP4 pre-mRNA processing factor 4 homolog B (yeast)	6p25.2	09087	17346	602338	NP_003904	NM_176800;NM_003913	ENSP00000433547	candidate	0	0	1	Last Universal Common Ancestor	27	1	Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of transcription	93	chr6	4031794	4060847	WES	breast
10594	PRPF8	PRP8 pre-mRNA processing factor 8 homolog (S. cerevisiae)	17p13.3	06295	17340	607300	NP_006436	NM_006445	ENSP00000304350	candidate	0	0	0	Eukaryotes	26	0	Cell response to stimuli,DNA/RNA metabolism and transcription,Regulation of transcription	109	chr17	1554099	1587865	WGS	lung
5631	PRPS1	phosphoribosyl pyrophosphate synthetase 1	Xq21.32-q24	02413	9462	311850	NP_001191331;NP_002755	NM_001204402;NM_002764	ENSP00000361512	candidate	0	0	3	Last Universal Common Ancestor	13	5	Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Development	107	chrX	106871859	106893259	WES	breast
7916	PRRC2A	proline-rich coiled-coil 2A	6p21.3	00807	13918	142580	NP_542417;NP_004629	NM_080686;NM_004638	ENSP00000365201;ENSP00000365175	candidate	0	0	0	Opisthokonts	55	1	-1	101	chr6	31590567	31605360	WES	breast
5396	PRRX1	paired related homeobox 1	1q24	01337	9142	167420	NP_008833;NP_073207	NM_006902;NM_022716	ENSP00000239461	known	1	0	0	Eukaryotes	5	3	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	88	chr1	170633360	170705324	CGC	leukemia
158471	PRUNE2	prune homolog 2 (Drosophila)	9q21.2	12970	25209	610691	NP_056040	NM_015225;NM_138818	ENSP00000365908	candidate	0	0	0	Eukaryotes	4	6	Cell cycle,Development,Regulation of intracellular processes and metabolism	91	chr9	79234258	79520879	WES	colorectal
11168	PSIP1	PC4 and SFRS1 interacting protein 1	9p22.3	04688	9527	603620	NP_150091;NP_066967;NP_001121689	NM_033222;NM_021144;NM_001128217	ENSP00000370114;ENSP00000380653;ENSP00000370109	known	1	0	0	Eukaryotes	23	5	Cellular metabolism,DNA/RNA metabolism and transcription,Multicellular activities,Other,Regulation of intracellular processes and metabolism,Regulation of transcription	96	chr9	15465521	15510186	CGC	leukemia
118672	PSTK	phosphoseryl-tRNA kinase	10q26.13	16586	28578	611310	NP_699167	NM_153336	ENSP00000357882	candidate	0	0	0	Last Universal Common Ancestor	1	0	Cellular metabolism,Regulation of intracellular processes and metabolism,Regulation of transcription	-1	chr10	124739996	124746480	WGS	liver
5727	PTCH1	patched 1	9q22.3	03200	9585	601309	NP_001077071;NP_001077073;NP_001077072;NP_000255;NP_001077074;NP_001077076;NP_001077075	NM_001083602;NM_001083604;NM_001083603;NM_000264;NM_001083605;NM_001083607;NM_001083606	ENSP00000332353;ENSP00000389744;ENSP00000399981;ENSP00000414823;ENSP00000396135	known	0	1	0	Eukaryotes	11	0	Cell cycle,Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction	78	chr9	98209197	98270643	CGC,WES,WGS	medulloblastoma,skin
8643	PTCH2	patched 2	1p34.1	04722	9586	603673	NP_003729;NP_001159764	NM_003738;NM_001166292	ENSP00000389703;ENSP00000361266	candidate	0	0	0	Eukaryotes	7	0	Development,Multicellular activities	22	chr1	45288090	45308604	WGS	breast
374308	PTCHD3	patched domain containing 3	10p12.1	-	24776	611791	NP_001030014	NM_001034842	ENSP00000417658	candidate	0	0	0	Eukaryotes	3	2	-1	-1	chr10	27687226	27703179	WGS	glioblastoma
5728	PTEN	phosphatase and tensin homolog	10q23.3	03431	9588	601728	NP_000305	NM_000314	-	known	0	1	1	Last Universal Common Ancestor	98	22	Cell cycle,Cell motility and interactions,Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	99	chr10	89624227	89725226	CGC,HTMS,WES,WGS	endometrium,glioma,prostate,breast,glioblastoma,lung,ovarian,pancreas,sarcoma,cholangiocarcinoma,colorectal,gastric,head and neck squamous cell carcinoma,medulloblastoma
5737	PTGFR	prostaglandin F receptor (FP)	1p31.1	08988	9600	600563	NP_000950;NP_001034674	NM_000959;NM_001039585	ENSP00000359793;ENSP00000359792	candidate	0	0	0	Metazoans	1	1	Signal transduction	4	chr1	78958429	79002369	HTMS	breast,lung,ovarian,pancreas,prostate
2185	PTK2B	PTK2B protein tyrosine kinase 2 beta	8p21.1	03131	9612	601212	NP_775268;NP_775267;NP_004094;NP_775266	NM_173176;NM_173175;NM_004103;NM_173174	ENSP00000380638;ENSP00000391995;ENSP00000332816	candidate	0	0	0	Last Universal Common Ancestor	97	2	Cell cycle,Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction	64	chr8	27255102	27316023	HTMS	sarcoma
5753	PTK6	PTK6 protein tyrosine kinase 6	20q13.3	03594	9617	602004	NP_001243287;NP_005966	NM_001256358;NM_005975	ENSP00000217185	known	0	0	0	Last Universal Common Ancestor	5	0	Cellular metabolism,Cellular processes	5	chr20	62160892	62168667	CGC,Amplified	
5763	PTMS	parathymosin	12p13	01344	9629	168440	NP_002815	NM_002824	ENSP00000310088	candidate	0	0	0	Vertebrates	21	4	Cellular metabolism,DNA/RNA metabolism and transcription	38	chr12	6875872	6879605	WGS	liver
5764	PTN	pleiotrophin	7q33	01199	9630	162095	NP_002816	NM_002825	ENSP00000341170	candidate	0	0	0	Metazoans	162	0	Cell cycle,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction	94	chr7	136935978	136939720	WES	gastric
5781	PTPN11	protein tyrosine phosphatase, non-receptor type 11	12q24	01470	9644	176876	NP_002825	NM_002834	ENSP00000340944;ENSP00000376376	known	1	0	5	Eukaryotes	46	7	Cell response to stimuli,Cellular metabolism,Cellular processes,Signal transduction	101	chr12	112884078	112942565	CGC	leukemia,myelodysplasia
5782	PTPN12	protein tyrosine phosphatase, non-receptor type 12	7q11.23	02513	9645	600079	NP_001124481;NP_002826;NP_001124480	NM_001131009;NM_002835;NM_001131008	ENSP00000397991;ENSP00000248594	candidate	0	0	0	Eukaryotes	46	7	Cellular metabolism,Cellular processes	82	chr7	77166864	77268594	WES	colorectal (hypermutated)
26191	PTPN22	protein tyrosine phosphatase, non-receptor type 22 (lymphoid)	1p13.2	06100	9652	600716	NP_001180360;NP_057051;NP_036543	NM_001193431;NM_015967;NM_012411	ENSP00000435176;ENSP00000352833	candidate	0	0	0	Eukaryotes	22	2	Cellular metabolism,Cellular processes,Signal transduction	19	chr1	114357530	114414245	WES	breast
5789	PTPRD	protein tyrosine phosphatase, receptor type, D	9p23-p24.3	03358	9668	601598	NP_569076;NP_569077;NP_001035802;NP_002830;NP_569075;NP_001164496	NM_130392;NM_130393;NM_001040712;NM_002839;NM_130391;NM_001171025	ENSP00000380735;ENSP00000380741;ENSP00000370593;ENSP00000347373	candidate	0	0	0	Eukaryotes	3	7	Cellular metabolism,Cellular processes,Signal transduction	68	chr9	8317877	8733843	HTMS,WES	lung,breast,colorectal,pancreas
5795	PTPRJ	protein tyrosine phosphatase, receptor type, J	11p11.2	02955	9673	600925	NP_002834;NP_001091973	NM_002843;NM_001098503	ENSP00000409733	candidate	0	0	0	Eukaryotes	37	8	Cellular metabolism,Cellular processes,Signal transduction	52	chr11	48002465	48188911	WGS	breast
5800	PTPRO	protein tyrosine phosphatase, receptor type, O	12p13.3-p13.2|12p13-p12	02784	9678	600579	NP_109593;NP_002839;NP_109594;NP_109596;NP_109592;NP_109595	NM_030668;NM_002848;NM_030669;NM_030671;NM_030667;NM_030670	ENSP00000343434;ENSP00000281171;ENSP00000439234;ENSP00000393449	candidate	0	0	0	Eukaryotes	25	2	Cellular metabolism,Cellular processes	109	chr12	15475661	15747972	WES	melanoma
5802	PTPRS	protein tyrosine phosphatase, receptor type, S	19p13.3	03344	9681	601576	NP_570925;NP_002841;NP_570923;NP_570924	NM_130855;NM_002850;NM_130853;NM_130854	ENSP00000349932;ENSP00000327313;ENSP00000269907	candidate	0	0	0	Eukaryotes	23	0	Cellular metabolism,Cellular processes	9	chr19	5206788	5286151	WES	colorectal
11122	PTPRT	protein tyrosine phosphatase, receptor type, T	20q12-q13	06690	9682	608712	NP_008981;NP_573400	NM_007050;NM_133170	ENSP00000362283;ENSP00000362294	candidate	0	0	0	Eukaryotes	19	1	Cellular metabolism,Cellular processes,Signal transduction	31	chr20	40709522	41818373	WGS	acute myeloid leukemia
10076	PTPRU	protein tyrosine phosphatase, receptor type, U	1p35.3	03908	9683	602454	NP_573439;NP_001181930;NP_573438;NP_005695	NM_133178;NM_001195001;NM_133177;NM_005704	ENSP00000392332;ENSP00000432906;ENSP00000362884	candidate	0	0	0	Eukaryotes	7	1	Cellular metabolism,Cellular processes,Signal transduction	52	chr1	29563157	29652170	WES	colorectal
284119	PTRF	polymerase I and transcript release factor	17q21.2	04433	9688	603198	NP_036364	NM_012232	ENSP00000349541	candidate	0	0	0	Vertebrates	47	3	Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	71	chr17	40556708	40575115	WGS	melanoma
79037	PVRIG	poliovirus receptor related immunoglobulin domain containing	7q22.1	-	32190	-	NP_076975	NM_024070	ENSP00000316675	candidate	0	0	1	Mammals	0	0	-1	46	chr7	99817534	99818871	WES	melanoma
7837	PXDN	peroxidasin homolog (Drosophila)	2p25	-	14966	605158	NP_036425	NM_012293	ENSP00000252804	candidate	0	0	0	Last Universal Common Ancestor	1	8	Cell response to stimuli,Cellular metabolism	90	chr2	1637979	1748227	WES	pancreas
137902	PXDNL	peroxidasin homolog (Drosophila)-like	8q11.22-q11.23	08693	26359	-	NP_653252	NM_144651	ENSP00000348645	candidate	0	0	0	Last Universal Common Ancestor	0	0	Cell response to stimuli,Cellular metabolism	-1	chr8	52232454	52721904	WGS	chronic lymphocytic leukemia
84074	QRICH2	glutamine rich 2	17q25.1	10891	25326	-	NP_115510	NM_032134	ENSP00000262765	candidate	0	0	0	Last Universal Common Ancestor	13	0	-1	-1	chr17	74271901	74301022	WGS	lymphoma
51715	RAB23	RAB23, member RAS oncogene family	6p11	05850	14263	606144	NP_057361;NP_899050	NM_016277;NM_183227	ENSP00000320413	known	0	0	0	Last Universal Common Ancestor	3	9	Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction	8	chr6	57055262	57075178	CGC,Amplified	
53917	RAB24	RAB24, member RAS oncogene family	5q35.3	06697	9765	612415	NP_570137;NP_001026847	NM_130781;NM_001031677	ENSP00000304376;ENSP00000377235	candidate	0	0	0	Last Universal Common Ancestor	23	0	Cellular processes,Signal transduction	-1	chr5	176728747	176730289	WGS	lymphoma
57111	RAB25	RAB25, member RAS oncogene family	1q22	06698	18238	612942	NP_065120	NM_020387	ENSP00000354376	known	0	0	0	Last Universal Common Ancestor	18	0	Cellular processes,Signal transduction	42	chr1	156035701	156040075	CGC,Amplified	
9135	RABEP1	rabaptin, RAB GTPase binding effector protein 1	17p13.2	04684	17677	603616	NP_001077054;NP_004694	NM_001083585;NM_004703	ENSP00000386150;ENSP00000262477	known	1	0	0	Metazoans	39	1	Cell cycle,Cellular processes	35	chr17	5211982	5286515	CGC	leukemia
5890	RAD51B	RAD51 homolog B (S. cerevisiae)	14q23-q24.2	04255	9822	602948	NP_002868;NP_598193;NP_598194	NM_002877;NM_133509;NM_133510	ENSP00000419471;ENSP00000418859	known	1	0	0	Last Universal Common Ancestor	5	0	Cell cycle,DNA/RNA metabolism and transcription	29	chr14	68290261	68934966	CGC	lipoma,uterus
23132	RAD54L2	RAD54-like 2 (S. cerevisiae)	3p21.2	10018	29123	-	NP_055921	NM_015106	ENSP00000386520	candidate	0	0	0	Last Universal Common Ancestor	36	1	-1	1	chr3	51624437	51697433	WGS	melanoma
55698	RADIL	Ras association and DIL domains	7p22.1	07663	22226	611491	NP_060529	NM_018059	ENSP00000382492	candidate	0	0	0	Eukaryotes	31	2	Signal transduction	-1	chr7	4839012	4917770	WES	cholangiocarcinoma
5894	RAF1	v-raf-1 murine leukemia viral oncogene homolog 1	3p25	01265	9829	164760	NP_002871	NM_002880	ENSP00000251849	known	1	0	0	Last Universal Common Ancestor	54	5	Cell cycle,Cellular metabolism,Cellular processes,Signal transduction	106	chr3	12626016	12660220	CGC,WGS	pilocytic astrocytoma,liver
5900	RALGDS	ral guanine nucleotide dissociation stimulator	9q34.3	03371	9842	601619	NP_006257;NP_001035827	NM_006266;NM_001042368	ENSP00000376867;ENSP00000361120	known	1	0	0	Metazoans	24	1	Signal transduction	100	chr9	135973977	135996541	CGC	lymphoma
64901	RANBP17	RAN binding protein 17	5q34	05847	14428	606141	NP_075048	NM_022897	ENSP00000427975	known	1	0	0	Eukaryotes	6	0	Cellular processes,DNA/RNA metabolism and transcription	25	chr5	170305101	170725859	CGC	leukemia
26953	RANBP6	RAN binding protein 6	9p24.1	17953	9851	-	NP_001230131;NP_001230132;NP_036548	NR_024094;NR_024095;NM_001243202;NM_001243203;NM_012416	ENSP00000259569	candidate	0	0	1	Eukaryotes	6	2	Cellular processes	61	chr9	6012293	6015607	WES	lymphoma
5910	RAP1GDS1	RAP1, GTP-GDP dissociation stimulator 1	4q23-q25	11763	9859	179502	NP_001093900;NP_001093896;NP_001093899;NP_001093898;NP_001093897;NP_066982	NM_001100430;NM_001100426;NM_001100429;NM_001100428;NM_001100427;NM_021159	ENSP00000386153	known	1	0	0	Eukaryotes	5	0	-1	72	chr4	99214555	99363265	CGC	leukemia
65059	RAPH1	Ras association (RalGDS/AF-6) and pleckstrin homology domains 1	2q33	12356	14436	609035	NP_976241;NP_998754	NM_025252;NM_203365;NM_213589	ENSP00000311293;ENSP00000316543	candidate	0	0	0	Eukaryotes	7	3	Signal transduction	-1	chr2	204304163	204360076	WES	breast
5914	RARA	retinoic acid receptor, alpha	17q21	06769	9864	180240	NP_001138773;NP_000955;NP_001019980;NP_001138774	NM_001033603;NM_001145301;NM_000964;NM_001024809;NM_001145302	-	known	1	0	1	Metazoans	63	3	Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	64	chr17	38487471	38512475	CGC	leukemia
5921	RASA1	RAS p21 protein activator (GTPase activating protein) 1	5q13.3	00745	9871	139150	NP_002881;NP_072179	NM_002890;NM_022650	ENSP00000411221	candidate	0	0	0	Eukaryotes	29	5	Cell cycle,Cell motility and interactions,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	104	chr5	86564269	86686697	WES	head and neck squamous cell carcinoma
9462	RASAL2	RAS protein activator like 2	1q24	05845	9874	606136	NP_004832;NP_733793	NM_004841;NM_170692	ENSP00000420558;ENSP00000407768	candidate	0	0	0	Eukaryotes	6	2	Signal transduction	18	chr1	178063628	178442371	WES	breast
158158	RASEF	RAS and EF-hand domain containing	9q21.32	08337	26464	611344	NP_689786	NM_152573	-	candidate	0	0	0	Last Universal Common Ancestor	1	1	Cellular processes,Signal transduction	-1	chr9	85597595	85677782	WGS	breast
221002	RASGEF1A	RasGEF domain family, member 1A	10q11.21	15211	24246	-	NP_660356	NM_145313	ENSP00000379155	candidate	0	0	0	Eukaryotes	1	1	Signal transduction	-1	chr10	43691923	43701564	WES	lymphoma
5924	RASGRF2	Ras protein-specific guanine nucleotide-releasing factor 2	5q13	07588	9876	606614	NP_008840	NM_006909	ENSP00000265080	candidate	0	0	0	Eukaryotes	2	0	Signal transduction	-1	chr5	80256558	80521586	WES	colorectal
166824	RASSF6	Ras association (RalGDS/AF-6) domain family member 6	4q13.3	15220	20796	612620	NP_803876;NP_958834	NM_177532;NM_201431	ENSP00000303877	candidate	0	0	0	Eukaryotes	6	6	Signal transduction	-1	chr4	74441955	74486217	WES,WGS	pancreas,chronic lymphocytic leukemia
11228	RASSF8	Ras association (RalGDS/AF-6) domain family (N-terminal) member 8	12p12.3	07084	13232	608231	NP_001158219;NP_001158220;NP_001158218;NP_009142	NM_001164747;NM_001164748;NM_001164746;NM_007211	ENSP00000443096;ENSP00000384491;ENSP00000370756	candidate	0	0	0	Opisthokonts	5	8	Signal transduction	10	chr12	26208277	26221748	WES	lung
5925	RB1	retinoblastoma 1	13q14.2	01574	9884	614041	NP_000312	NM_000321	ENSP00000267163	known	0	1	0	Eukaryotes	202	16	Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	65	chr13	48878049	49054204	CGC,HTMS,WES,WGS	breast,lung,retinoblastoma,sarcoma,glioblastoma,bladder,prostate
10741	RBBP9	retinoblastoma binding protein 9	20p11.2	04217	9892	602908	NP_006597	NM_006606;NM_153328	ENSP00000336866	candidate	0	0	0	Last Universal Common Ancestor	7	3	-1	18	chr20	18470411	18477811	WGS	chronic lymphocytic leukemia
54715	RBFOX1	RNA binding protein, fox-1 homolog (C. elegans) 1	16p13.3	16091	18222	605104	NP_001135806;NP_665898;NP_665900;NP_061193;NP_001135805;NP_665899	NM_001142334;NM_145891;NM_145893;NM_018723;NM_001142333;NM_145892	ENSP00000344196	candidate	0	0	0	Eukaryotes	45	2	Cellular processes,DNA/RNA metabolism and transcription,Regulation of transcription	48	chr16	7383003	7760744	WGS	lymphoma
64783	RBM15	RNA binding motif protein 15	1p13	05832	14959	606077	NP_001188474;NP_073605	NM_001201545;NM_022768	ENSP00000358799	known	1	0	1	Eukaryotes	18	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	36	chr1	110882028	110888228	CGC	leukemia
9904	RBM19	RNA binding motif protein 19	12q24.21	15225	29098	-	NP_001140171;NP_057280;NP_001140170	NM_001146699;NM_016196;NM_001146698	ENSP00000376344;ENSP00000442053;ENSP00000261741	candidate	0	0	0	Last Universal Common Ancestor	1	3	-1	49	chr12	114261032	114400219	WGS	liver
54439	RBM27	RNA binding motif protein 27	5q32	-	29243	-	NP_061862	NM_018989	ENSP00000265271	candidate	0	0	0	Eukaryotes	12	0	-1	-1	chr5	145583329	145665590	WES	glioblastoma
54502	RBM47	RNA binding motif protein 47	4p14	-	30358	-	NP_061900;NP_001092104	NM_019027;NM_001098634	ENSP00000371212;ENSP00000371214	candidate	0	0	0	Eukaryotes	3	6	-1	65	chr4	40427924	40440910	WGS	breast,lymphoma
51634	RBMX2	RNA binding motif protein, X-linked 2	Xq26.1	06470	24282	-	NP_057108	NM_016024	ENSP00000339090	candidate	0	0	3	Last Universal Common Ancestor	5	0	-1	70	chrX	129536230	129546819	WGS	breast
9985	REC8	REC8 homolog (yeast)	14q11.2-q12	09739	16879	608193	NP_001041670;NP_005123	NM_001048205;NM_005132	ENSP00000453242;ENSP00000308699	candidate	0	0	0	Last Universal Common Ancestor	4	0	Cell cycle,DNA/RNA metabolism and transcription,Development,Multicellular activities	86	chr14	24641762	24649298	WGS	glioblastoma
9401	RECQL4	RecQ protein-like 4	8q24.3	04805	9949	603780	NP_004251	NM_004260	-	known	0	1	0	Last Universal Common Ancestor	13	1	Cell cycle,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism	2	chr8	145736817	145743168	CGC	
5966	REL	v-rel reticuloendotheliosis viral oncogene homolog (avian)	2p13-p12	01286	9954	164910	NP_002899	NM_002908	ENSP00000295025	known	1	0	0	Metazoans	70	1	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	50	chr2	61118814	61149667	CGC,Amplified	lymphoma
79785	RERGL	RERG/RAS-like	12p12.3	08659	26213	-	NP_079006	NM_024730	ENSP00000229002	candidate	0	0	0	Last Universal Common Ancestor	0	1	Signal transduction	5	chr12	18234128	18242217	WGS	chronic lymphocytic leukemia
5978	REST	RE1-silencing transcription factor	4q12	08990	9966	600571	NP_005603;NP_001180437	NM_005612;NM_001193508	ENSP00000311816	candidate	0	0	0	Eukaryotes	31	5	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	28	chr4	57776805	57798315	WGS	melanoma
5979	RET	ret proto-oncogene	10q11.2	01266	9967	164761	NP_066124;NP_065681	NM_020975;NM_000323;NM_020629;NM_020630	ENSP00000344798;ENSP00000347942	known	1	0	0	Last Universal Common Ancestor	45	3	Cell motility and interactions,Cellular metabolism,Cellular processes,Development,Signal transduction	66	chr10	43595894	43623714	CGC,HTMS,WES	lung,pheochromocytoma,thyroid,breast,ovarian,pancreas,prostate,colorectal,lymphoma
5982	RFC2	replication factor C (activator 1) 2, 40kDa	7q11.23	02675	9970	600404	NP_002905;NP_852136	NM_002914;NM_181471	ENSP00000275627;ENSP00000055077	candidate	0	0	1	Last Universal Common Ancestor	12	2	Cellular metabolism,DNA/RNA metabolism and transcription	44	chr7	73646439	73668713	WGS	liver
23180	RFTN1	raftlin, lipid raft linker 1	3p24.3	17950	30278	-	NP_055965	NM_015150	ENSP00000334153	candidate	0	0	0	Metazoans	2	0	-1	98	chr3	16358338	16535376	WES	chronic lymphocytic leukemia
64326	RFWD2	ring finger and WD repeat domain 2	1q25.1-q25.2	07455	17440	608067	NP_071902;NP_001001740	NM_022457;NM_001001740	ENSP00000356641	candidate	0	0	1	Last Universal Common Ancestor	64	2	-1	-1	chr1	175916328	176176114	WGS	prostate
5990	RFX2	regulatory factor X, 2 (influences HLA class II expression)	19p13.3	00824	9983	142765	NP_000626;NP_602309	NM_000635;NM_134433	ENSP00000306335	candidate	0	0	0	Eukaryotes	2	4	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	12	chr19	5994849	6047507	WES	breast
57529	RGAG1	retrotransposon gag domain containing 1	Xq23	06600	29245	-	NP_065820	NM_020769	ENSP00000419786	candidate	0	0	0	Last Universal Common Ancestor	1	0	-1	-1	chrX	109693846	109698546	WES	lymphoma
23179	RGL1	ral guanine nucleotide dissociation stimulator-like 1	1q25.3	12032	30281	605667	NP_055964	NM_015149	ENSP00000303192	candidate	0	0	0	Metazoans	3	0	Signal transduction	92	chr1	183711293	183895423	WES	breast
6002	RGS12	regulator of G-protein signaling 12	4p16.3	03943	9994	602512	NP_937872;NP_937870;NP_002917	NM_198229;NM_198230;NM_198430;NM_198587;NM_198227;NM_198432;NM_002926	ENSP00000338509;ENSP00000342133;ENSP00000339381	candidate	0	0	0	Eukaryotes	9	0	Regulation of intracellular processes and metabolism,Signal transduction	64	chr4	3317898	3441408	WES	lymphoma
121268	RHEBL1	Ras homolog enriched in brain like 1	12q13.12	15245	21166	-	NP_653194	NM_144593	ENSP00000301068	candidate	0	0	0	Last Universal Common Ancestor	13	3	Signal transduction	-1	chr12	49458889	49463568	HTMS	breast,lung,ovarian,pancreas,prostate
387	RHOA	ras homolog gene family, member A	3p21.3	01323	667	165390	NP_001655	NM_001664	ENSP00000400175	candidate	0	0	3	Last Universal Common Ancestor	29	9	Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction	109	chr3	49397645	49413022	WES,WGS	lymphoma
388	RHOB	ras homolog gene family, member B	2p24	01321	668	165370	NP_004031	NM_004040	ENSP00000272233	candidate	0	0	2	Last Universal Common Ancestor	21	5	Cell cycle,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction	104	chr2	20647227	20647814	WGS	melanoma
399	RHOH	ras homolog gene family, member H	4p13	03616	686	602037	NP_004301	NM_004310	ENSP00000371219	known	1	0	0	Last Universal Common Ancestor	15	0	Cellular metabolism,DNA/RNA metabolism and transcription,Development,Immune system response,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	32	chr4	40245007	40245579	CGC	non-hodgkin lymphoma
23504	RIMBP2	RIMS binding protein 2	12q24.33	17183	30339	611602	NP_056162	NM_015347	ENSP00000261655	candidate	0	0	0	Eukaryotes	3	0	-1	34	chr12	130884224	130963558	WES	head and neck squamous cell carcinoma
9699	RIMS2	regulating synaptic membrane exocytosis 2	8q22.3	09436	17283	606630	NP_055492;NP_001093587	NM_014677;NM_001100117	-	candidate	0	0	0	Eukaryotes	18	2	Cellular processes	54	chr8	104513115	105264045	WES	breast,chronic lymphocytic leukemia,head and neck squamous cell carcinoma,lung
6014	RIT2	Ras-like without CAAX 2	18q12.3	15253	10017	609592	NP_002921	NM_002930	ENSP00000321805	candidate	0	0	0	Last Universal Common Ancestor	12	0	Multicellular activities,Signal transduction	29	chr18	40323461	40695484	WES	gastric
116028	RMI2	RMI2, RecQ mediated genome instability 2, homolog (S. cerevisiae)	16p13.13	14497	28349	612426	NP_689521	NM_152308	ENSP00000310356	known	1	0	0	Eukaryotes	6	0	-1	-1	chr16	11439329	11444644	CGC	lymphoma
10535	RNASEH2A	ribonuclease H2, subunit A	19p13.2	06914	18518	606034	NP_006388	NM_006397	ENSP00000221486	candidate	0	0	0	Last Universal Common Ancestor	0	0	Cellular metabolism,DNA/RNA metabolism and transcription	98	chr19	12917488	12924277	WGS	breast
7844	RNF103	ring finger protein 103	2p11.2	03939	12859	602507	NP_001185881;NP_005658;NP_001185880	NM_001198952;NM_005667;NM_001198951	ENSP00000237455	candidate	0	0	0	Eukaryotes	21	0	Development	92	chr2	86830969	86850009	WES	chronic lymphocytic leukemia
138065	RNF183	ring finger protein 183	9q32	10082	28721	-	NP_659488	NM_145051	ENSP00000417176	candidate	0	0	0	Eukaryotes	7	1	-1	-1	chr9	116059889	116060464	WGS	prostate
388591	RNF207	ring finger protein 207	1p36.31	13536	32947	-	NP_997279	NM_173795;NM_207396	ENSP00000367173	candidate	0	0	0	Eukaryotes	0	0	-1	-1	chr1	6266596	6279464	WES	pancreas
57674	RNF213	ring finger protein 213	17q25.3	10716	14539	613768	NP_001243000;NP_066005;NP_065965	NM_001256071;NM_020954;NM_020914	ENSP00000464087;ENSP00000324392	known	1	0	0	Eukaryotes	5	3	-1	-1	chr17	78237481	78367295	CGC	lymphoma
79596	RNF219	ring finger protein 219	13q31.1	12619	20308	-	NP_078822	NM_024546	ENSP00000282003	candidate	0	0	0	Metazoans	10	5	-1	65	chr13	79189718	79233255	WES	colorectal
55182	RNF220	ring finger protein 220	1p34.1	13336	25552	-	NP_060620	NM_018150	ENSP00000354872	candidate	0	0	0	Eukaryotes	10	0	-1	84	chr1	44877770	45116444	WGS	breast
54894	RNF43	ring finger protein 43	17q22	07896	18505	612482	NP_060233	NM_017763	ENSP00000462764	candidate	0	0	0	Eukaryotes	22	1	-1	40	chr17	56432307	56492938	WES	cholangiocarcinoma
6091	ROBO1	roundabout, axon guidance receptor, homolog 1 (Drosophila)	3p12	03890	10249	602430	NP_598334;NP_002932;NP_001139317	NM_133631;NM_002941;NM_001145845	ENSP00000420321;ENSP00000406043	candidate	0	0	0	Last Universal Common Ancestor	17	1	Cell cycle,Cell motility and interactions,Development,Regulation of intracellular processes and metabolism	58	chr3	78649263	79639061	WES,WGS	colorectal,chronic lymphocytic leukemia
6092	ROBO2	roundabout, axon guidance receptor, homolog 2 (Drosophila)	3p12.3	-	10250	602431	NP_001122401;NP_002933	NM_001128929;NM_002942	ENSP00000417335;ENSP00000417164	candidate	0	0	0	Last Universal Common Ancestor	30	1	Cell cycle,Cell motility and interactions,Development,Regulation of intracellular processes and metabolism	-1	chr3	77147164	77694054	WES	cholangiocarcinoma
6098	ROS1	c-ros oncogene 1 , receptor tyrosine kinase	6q22	01295	10261	165020	NP_002935	NM_002944	ENSP00000357494	known	1	0	0	Last Universal Common Ancestor	9	1	Cellular metabolism,Cellular processes,Signal transduction	49	chr6	117609658	117746819	CGC,HTMS,WES	glioblastoma,lung,breast,ovarian,pancreas,prostate,chronic lymphocytic leukemia
6101	RP1	retinitis pigmentosa 1 (autosomal dominant)	8q12.1	04896	10263	603937	NP_006260	NM_006269	ENSP00000220676	candidate	0	0	0	Last Universal Common Ancestor	1	1	Cell response to stimuli,Signal transduction	-1	chr8	55533527	55542910	WGS	breast,melanoma
94137	RP1L1	retinitis pigmentosa 1-like 1	8p23.1	10546	15946	608581	NP_849188	NM_178857	ENSP00000371923	candidate	0	0	0	Eukaryotes	4	1	Cell response to stimuli,Signal transduction	-1	chr8	10464408	10480711	WES	breast
6103	RPGR	retinitis pigmentosa GTPase regulator	Xp21.1	02425	10295	312610	NP_000319;NP_001030025	NM_000328;NM_001023582;NM_001034853	ENSP00000322219;ENSP00000367766	candidate	0	0	0	Last Universal Common Ancestor	15	1	Cell response to stimuli,Cellular processes	41	chrX	38144796	38182778	WES	breast
57096	RPGRIP1	retinitis pigmentosa GTPase regulator interacting protein 1	14q11	05673	13436	605446	NP_065099	NM_020366	ENSP00000382895	candidate	0	0	0	Eukaryotes	4	1	Cell response to stimuli	82	chr14	21756136	21819372	WES	breast
100287887	RPL13AP25	ribosomal protein L13a pseudogene 25	13q14.3	-	36981	-	-	-	-	candidate	0	0	-1	Last Universal Common Ancestor	0	0	Cellular metabolism,Regulation of transcription	-1	-	0	0	WES	pancreas
6146	RPL22	ribosomal protein L22	1p36.31	01602	10315	180474	NP_000974	NM_000983	ENSP00000346088	known	1	0	17	Eukaryotes	89	0	Cellular metabolism,Regulation of transcription	109	chr1	6246735	6257816	CGC,WES	leukemia,gastric
6184	RPN1	ribophorin I	3q21.3	01598	10381	180470	NP_002941	NM_002950	ENSP00000296255	known	1	0	0	Eukaryotes	22	2	Cellular metabolism,Cellular processes	104	chr3	128339257	128369643	CGC	leukemia
6196	RPS6KA2	ribosomal protein S6 kinase, 90kDa, polypeptide 2	6q27	03403	10431	601685	NP_066958;NP_001006933	NM_021135;NM_001006932	ENSP00000422435;ENSP00000265678	candidate	0	0	2	Last Universal Common Ancestor	22	1	Cellular metabolism,Cellular processes,Signal transduction	95	chr6	166826253	167275658	WGS	melanoma
6197	RPS6KA3	ribosomal protein S6 kinase, 90kDa, polypeptide 3	Xp22.2-p22.1	02092	10432	300075	NP_004577	NM_004586	ENSP00000368884	candidate	0	0	2	Last Universal Common Ancestor	45	3	Cellular metabolism,Cellular processes,Development,Signal transduction	72	chrX	20173519	20284750	WES	liver
6198	RPS6KB1	ribosomal protein S6 kinase, 70kDa, polypeptide 1	17q23.1	10202	10436	608938	NP_003152	NM_003161	ENSP00000225577	known	0	0	1	Last Universal Common Ancestor	78	7	Cellular metabolism,Cellular processes,Signal transduction	45	chr17	57970546	58024146	CGC,Amplified	
23378	RRP8	ribosomal RNA processing 8, methyltransferase, homolog (yeast)	11p15.4	13800	29030	-	NP_056139	NM_015324	-	candidate	0	0	0	Last Universal Common Ancestor	8	1	-1	44	chr11	6621379	6624732	WES	acute myeloid leukemia
25914	RTTN	rotatin	18q22.2	11525	18654	610436	NP_775901	NM_173630	ENSP00000255674	candidate	0	0	0	Eukaryotes	1	0	-1	-1	chr18	67671390	67872552	WES	chronic lymphocytic leukemia
80230	RUFY1	RUN and FYVE domain containing 1	5q35.3	15282	19760	610327	NP_001035541;NP_079434;NP_001035542	NM_001040451;NM_025158;NM_001040452	ENSP00000390025;ENSP00000377087;ENSP00000325594	candidate	0	0	0	Eukaryotes	16	0	Cellular processes	107	chr5	178977571	179036517	WES	head and neck squamous cell carcinoma
861	RUNX1	runt-related transcription factor 1	21q22.3	01043	10471	151385	NP_001001890;NP_001745;NP_001116079	NM_001001890;NM_001754;NM_001122607	ENSP00000340690;ENSP00000351123;ENSP00000409227	known	1	0	0	Metazoans	81	3	Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription	66	chr21	36164435	36421196	CGC,WES	leukemia,acute myeloid leukemia,breast,myelodysplasia
862	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)	8q22	00590	1535	133435	NP_783554;NP_001185559;NP_001185608;NP_001185561;NP_001185562;NP_001185560;NP_001185558;NP_001185563;NP_783552;NP_001185554;NP_001185555;NP_783553;NP_001185556;NP_001185557;NP_004340	NM_175636;NM_001198630;NM_001198679;NM_001198632;NM_001198633;NM_001198631;NM_001198629;NM_001198634;NM_175634;NM_001198625;NM_001198626;NM_175635;NM_001198627;NM_001198628;NM_004349	ENSP00000428543	known	1	0	0	Opisthokonts	60	5	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	87	chr8	92972473	93107695	CGC,HTMS,WES	leukemia,breast,lung,ovarian,pancreas,prostate,acute myeloid leukemia,colorectal
8607	RUVBL1	RuvB-like 1 (E. coli)	3q21	09143	10474	603449	NP_003698	NM_003707	ENSP00000318297	known	0	0	0	Last Universal Common Ancestor	185	1	Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription	29	chr3	127800096	127842567	CGC,Amplified	
51289	RXFP3	relaxin/insulin-like family peptide receptor 3	5p15.1-p14	17979	24883	609445	NP_057652	NM_016568	ENSP00000328708	candidate	0	0	0	Metazoans	2	2	Regulation of intracellular processes and metabolism,Signal transduction	1	chr5	33936846	33938252	WES	head and neck squamous cell carcinoma
6261	RYR1	ryanodine receptor 1 (skeletal)	19q13.1	01618	10483	180901	NP_001036188;NP_000531	NM_001042723;NM_000540	ENSP00000352608;ENSP00000347667	candidate	0	0	0	Last Universal Common Ancestor	22	0	Cellular processes,Multicellular activities,Regulation of intracellular processes and metabolism	41	chr19	38924470	39078057	WES	acute myeloid leukemia,kidney
6262	RYR2	ryanodine receptor 2 (cardiac)	1q43	01619	10484	180902	NP_001026	NM_001035	ENSP00000355533	candidate	0	0	0	Last Universal Common Ancestor	30	1	Cell cycle,Cellular processes,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction	25	chr1	237205822	237995944	WES	breast,chronic lymphocytic leukemia
6263	RYR3	ryanodine receptor 3	15q14-q15	01620	10485	180903	NP_001027;NP_001230925	NM_001036;NM_001243996	ENSP00000373884;ENSP00000399610	candidate	0	0	0	Last Universal Common Ancestor	7	4	Cellular processes,Regulation of intracellular processes and metabolism	66	chr15	33603247	34157424	WGS	lung
9294	S1PR2	sphingosine-1-phosphate receptor 2	19p13.2	05488	3169	605111	NP_004221	NM_004230	-	candidate	0	0	0	Vertebrates	12	0	Cell cycle,Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction	1	chr19	10334523	10335581	WES	lymphoma
55511	SAGE1	sarcoma antigen 1	Xq26	02290	30369	300359	NP_061136	NM_018666	ENSP00000445959	candidate	0	0	1	Eukaryotes	0	0	-1	4	chrX	134978402	134995053	WES	pancreas
27164	SALL3	sal-like 3 (Drosophila)	18q23	05467	10527	605079	NP_741996	NM_171999	-	candidate	0	0	0	Opisthokonts	21	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	-1	chr18	76740275	76757319	WES	lymphoma
219285	SAMD9L	sterile alpha motif domain containing 9-like	7q21.2	10798	1349	611170	NP_689916	NM_152703	ENSP00000326247	candidate	0	0	0	Last Universal Common Ancestor	2	1	-1	-1	chr7	92760533	92765284	WES	liver
1757	SARDH	sarcosine dehydrogenase	9q33-q34	06831	10536	604455	NP_009032;NP_001128179	NM_007101;NM_001134707	ENSP00000403084;ENSP00000360938	candidate	0	0	0	Last Universal Common Ancestor	2	0	Cellular metabolism	38	chr9	136529014	136599295	WES	acute myeloid leukemia
23314	SATB2	SATB homeobox 2	2q33	12178	21637	608148	NP_001165988;NP_056080;NP_001165980	NM_001172517;NM_015265;NM_001172509	ENSP00000401112;ENSP00000260926	candidate	0	0	0	Metazoans	6	2	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	26	chr2	200136937	200320760	WES	lung
60485	SAV1	salvador homolog 1 (Drosophila)	14q13-q23	06229	17795	607203	NP_068590	NM_021818	ENSP00000324729	candidate	0	0	0	Eukaryotes	14	4	Signal transduction	56	chr14	51101904	51134685	HTMS	breast,lung,ovarian,pancreas,prostate
51119	SBDS	Shwachman-Bodian-Diamond syndrome	7q11.21	07393	19440	607444	NP_057122	NM_016038	ENSP00000246868	known	0	1	1	Last Universal Common Ancestor	33	1	Cell cycle,Cell motility and interactions,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Immune system response,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription	-1	chr7	66453361	66460404	CGC	
58506	SCAF1	SR-related CTD-associated factor 1	19q13.3-q13.4	11604	30403	-	NP_067051	NM_021228	ENSP00000353769	candidate	0	0	0	Eukaryotes	6	3	DNA/RNA metabolism and transcription,Regulation of transcription	-1	chr19	50148284	50161653	WGS	melanoma
49855	SCAPER	S-phase cyclin A-associated protein in the ER	15q24	11704	13081	611611	NP_065894;NP_001139395	NM_020843;NM_001145923	ENSP00000442190;ENSP00000326924	candidate	0	0	0	Eukaryotes	7	0	-1	91	chr15	76640977	77154874	WGS	lung
8796	SCEL	sciellin	13q22	09161	10573	604112	NP_001154178;NP_003834;NP_659001	NM_001160706;NM_003843;NM_144777	ENSP00000437895;ENSP00000366454	candidate	0	0	0	Eukaryotes	5	0	Development	6	chr13	78130011	78216948	WGS	breast
132320	SCLT1	sodium channel and clathrin linker 1	4q28.2	08700	26406	611399	NP_653244	NM_144643	ENSP00000281142	candidate	0	0	0	Eukaryotes	2	0	-1	-1	chr4	129805635	130003526	WGS	chronic lymphocytic leukemia
11280	SCN11A	sodium channel, voltage-gated, type XI, alpha subunit	3p22.2	05090	10583	604385	NP_054858	NM_014139	ENSP00000307599	candidate	0	0	0	Last Universal Common Ancestor	0	0	Cellular processes	58	chr3	38888188	38991853	WES,WGS	prostate,chronic lymphocytic leukemia
6328	SCN3A	sodium channel, voltage-gated, type III, alpha subunit	2q24	01671	10590	182391	NP_001075146;NP_001075145;NP_008853	NM_001081677;NM_001081676;NM_006922	ENSP00000353206;ENSP00000283254	candidate	0	0	4	Last Universal Common Ancestor	3	6	Cellular processes	25	chr2	165946663	166032904	WGS	melanoma
55800	SCN3B	sodium channel, voltage-gated, type III, beta	11q23.3	10497	20665	608214	NP_060870;NP_001035241	NM_018400;NM_001040151	ENSP00000299333;ENSP00000376523	candidate	0	0	0	Vertebrates	16	1	Cellular processes	49	chr11	123504854	123524509	WES	colorectal
6331	SCN5A	sodium channel, voltage-gated, type V, alpha subunit	3p21	02543	10593	600163	NP_932173;NP_001092874;NP_001153632;NP_001092875;NP_001153633;NP_000326	NM_198056;NM_001099404;NM_001160160;NM_001099405;NM_001160161;NM_000335	ENSP00000397915;ENSP00000410257;ENSP00000416634;ENSP00000399524;ENSP00000388797;ENSP00000328968	candidate	0	0	0	Last Universal Common Ancestor	22	0	Cellular processes,Multicellular activities	18	chr3	38591815	38674798	WES	pancreas
6335	SCN9A	sodium channel, voltage-gated, type IX, alpha subunit	2q24	04565	10597	603415	NP_002968	NM_002977	ENSP00000386306	candidate	0	0	3	Last Universal Common Ancestor	0	1	Cellular processes	2	chr2	167055185	167168266	WES	glioblastoma
85508	SCRT2	scratch homolog 2, zinc finger protein (Drosophila)	20p13	15305	15952	-	NP_149120	NM_033129	ENSP00000246104	candidate	0	0	0	Last Universal Common Ancestor	0	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	-1	chr20	644318	656245	WGS	liver
6385	SDC4	syndecan 4	20q12	08366	10661	600017	NP_002990	NM_002999	ENSP00000361818	known	1	0	0	Vertebrates	19	5	-1	94	chr20	43955907	43977024	CGC	lung
51150	SDF4	stromal cell derived factor 4	1p36.33	13113	24188	614282	NP_057631;NP_057260	NM_016547;NM_016176	ENSP00000353094;ENSP00000263741	candidate	0	0	0	Eukaryotes	21	0	-1	109	chr1	1152895	1164173	WGS	glioblastoma
54949	SDHAF2	succinate dehydrogenase complex assembly factor 2	11q12.2	07915	26034	613019	NP_060311	NM_017841	-	known	0	1	0	Last Universal Common Ancestor	27	2	-1	-1	chr11	61205097	61213540	CGC	
6390	SDHB	succinate dehydrogenase complex, subunit B, iron sulfur (Ip)	1p36.1-p35	01707	10681	185470	NP_002991	NM_003000	ENSP00000364649	known	0	1	0	Last Universal Common Ancestor	54	1	Cellular metabolism	98	chr1	17345379	17380514	CGC	
6391	SDHC	succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa	1q23.3	03878	10682	602413	NP_001030589;NP_001030588;NP_001030590;NP_002992	NM_001035512;NM_001035511;NM_001035513;NM_003001	-	known	0	1	8	Last Universal Common Ancestor	8	3	Cellular metabolism	109	chr1	161293402	161332220	CGC	
6392	SDHD	succinate dehydrogenase complex, subunit D, integral membrane protein	11q23	04069	10683	602690	NP_002993	NM_003002	ENSP00000364699	known	0	1	7	Eukaryotes	1	0	Cellular metabolism	102	chr11	111957632	111965691	CGC	
266629	SEC14L3	SEC14-like 3 (S. cerevisiae)	22q12.2	15311	18655	612824	NP_777635	NM_174975	ENSP00000385004;ENSP00000383896;ENSP00000444691;ENSP00000215812	candidate	0	0	0	Eukaryotes	0	4	-1	1	chr22	30856011	30867945	WGS	glioblastoma
223117	SEMA3D	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D	7q21.11	15321	10726	609907	NP_689967	NM_152754	ENSP00000284136	candidate	0	0	0	Eukaryotes	19	0	Development	6	chr7	84628759	84751207	WES	colorectal
9723	SEMA3E	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E	7q21.11	11545	10727	608166	NP_001171600;NP_036563	NM_001178129;NM_012431	ENSP00000303212	candidate	0	0	0	Eukaryotes	1	0	Development	4	chr7	82996905	83277858	WES	gastric
54437	SEMA5B	sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B	3q21.1	15322	10737	609298	NP_001243276;NP_001026872;NP_001243277;NP_001243275	NR_046079;NM_001256347;NM_001031702;NM_018987;NM_001256348;NM_001256346	ENSP00000350215;ENSP00000389588	candidate	0	0	0	Eukaryotes	12	0	Development	-1	chr3	122628993	122680110	WES	breast,pancreas
22929	SEPHS1	selenophosphate synthetase 1	10p14	02944	19685	600902	NP_036379;NP_001182531;NP_001182533	NM_012247;NM_001195602;NM_001195604	ENSP00000367887;ENSP00000367893	candidate	0	0	4	Last Universal Common Ancestor	36	1	Cellular metabolism,Cellular processes	98	chr10	13361145	13386950	WGS	chronic lymphocytic leukemia
22928	SEPHS2	selenophosphate synthetase 2	16p11.2	12096	19686	606218	NP_036380	NM_012248	ENSP00000418669	candidate	0	0	1	Last Universal Common Ancestor	1	0	Cellular metabolism	102	chr16	30455705	30457048	WES	breast
5413	SEPT5	septin 5	22q11.21	04100	9164	602724	NP_002679;NP_001009939	NM_002688;NM_001009939	ENSP00000394541;ENSP00000391311	known	1	0	0	Eukaryotes	10	0	Cellular processes,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction	11	chr22	19702112	19710004	CGC	leukemia
23157	SEPT6	septin 6	Xq24	06716	15848	300683	NP_665799;NP_665798;NP_055944;NP_665801	NM_145800;NM_145799;NM_015129;NM_145802	ENSP00000378108;ENSP00000353278	known	1	0	2	Eukaryotes	16	2	-1	96	chrX	118763283	118809631	CGC	leukemia
641977	SEPT7P2	septin 7 pseudogene 2	7p12.3	-	32339	611563	-	NR_024271	-	candidate	0	0	-1	Eukaryotes	0	0	-1	-1	-	0	0	WES	breast
10801	SEPT9	septin 9	17q25	10360	7323	604061	NP_001106964;NP_001106967;NP_001106965;NP_001106968;NP_001106966;NP_001106963;NP_006631	NM_001113492;NM_001113495;NM_001113493;NM_001113496;NM_001113494;NM_001113491;NM_006640	ENSP00000391249;ENSP00000400181;ENSP00000405877;ENSP00000403194;ENSP00000415624;ENSP00000438089;ENSP00000329161	known	1	0	0	Eukaryotes	187	3	Cell cycle,Cellular metabolism,Regulation of intracellular processes and metabolism	105	chr17	75303222	75494737	CGC,HTMS	leukemia,breast,lung,ovarian,pancreas,prostate
5265	SERPINA1	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1	14q32.1	02463	8941	107400	NP_001121179;NP_001121172;NP_001121176;NP_001121177;NP_001002235;NP_000286;NP_001121174;NP_001002236;NP_001121178;NP_001121173;NP_001121175	NM_001127707;NM_001127700;NM_001127704;NM_001127705;NM_001002235;NM_000295;NM_001127702;NM_001002236;NM_001127706;NM_001127701;NM_001127703	ENSP00000390299;ENSP00000348068;ENSP00000416066;ENSP00000408474	candidate	0	0	0	Last Universal Common Ancestor	37	1	Cell response to stimuli,Immune system response,Multicellular activities	75	chr14	94844789	94849574	WES	lymphoma
145264	SERPINA12	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12	14q32.13	18038	18359	-	NP_776249	NM_173850	ENSP00000342109	candidate	0	0	0	Last Universal Common Ancestor	1	0	-1	-1	chr14	94953643	94964734	WES	glioblastoma
866	SERPINA6	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6	14q32.1	00419	1540	122500	NP_001747	NM_001756	ENSP00000342850	candidate	0	0	0	Last Universal Common Ancestor	0	0	-1	31	chr14	94770758	94780985	WGS	melanoma
6418	SET	SET nuclear oncogene	9q34	09023	10760	600960	NP_003002;NP_001234929;NP_001116293;NP_001234930	NM_003011;NM_001248000;NM_001122821;NM_001248001	ENSP00000361777;ENSP00000318012	known	1	0	11	Eukaryotes	117	3	Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism	109	chr3	155705093	155705962	CGC	leukemia
26040	SETBP1	SET binding protein 1	18q21.1	10224	15573	611060	NP_001123582;NP_056374	NM_001130110;NM_015559	ENSP00000390687;ENSP00000282030	candidate	0	0	0	Eukaryotes	0	0	-1	60	chr18	42281312	42643660	WES	leukemia
29072	SETD2	SET domain containing 2	3p21.31	11043	18420	612778	NP_054878	NM_012271;NM_014159	ENSP00000386759	known	0	1	0	Last Universal Common Ancestor	16	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	99	chr3	47058586	47205414	CGC,HTMS,WES	kidney,breast
55209	SETD5	SET domain containing 5	3p25.3	-	25566	-	NP_001073986	NM_018187;NM_001080517	ENSP00000385852	candidate	0	0	0	Eukaryotes	6	1	-1	93	chr3	9470623	9517772	WGS	chronic lymphocytic leukemia
23451	SF3B1	splicing factor 3b, subunit 1, 155kDa	2q33.1	09281	10768	605590	NP_001005526;NP_036565	NM_001005526;NM_012433	ENSP00000402997;ENSP00000335321	known	1	0	0	Eukaryotes	214	0	DNA/RNA metabolism and transcription,Development,Regulation of transcription	109	chr2	198257030	198288699	CGC,WES,WGS	myelodysplastic syndrome,breast,chronic lymphocytic leukemia,pancreas,medulloblastoma
6421	SFPQ	splicing factor proline/glutamine-rich	1p34.3	07284	10774	605199	NP_005057	NM_005066	ENSP00000349748	known	1	0	0	Metazoans	146	3	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	107	chr1	35650060	35658650	CGC	kidney
119559	SFXN4	sideroflexin 4	10q26.11	18046	16088	-	NP_998814	NM_178867;NM_213649	ENSP00000347924	candidate	0	0	0	Eukaryotes	5	0	Cellular processes	-1	chr10	120900757	120925159	WES	pancreas
6446	SGK1	serum/glucocorticoid regulated kinase 1	6q23	04264	10810	602958	NP_005618;NP_001137150;NP_001137148;NP_001137149	NM_005627;NM_001143678;NM_001143676;NM_001143677	ENSP00000356832;ENSP00000396242;ENSP00000237305	candidate	0	0	0	Last Universal Common Ancestor	97	3	Cell cycle,Cellular metabolism,Cellular processes	95	chr6	134491409	134638598	WES	lymphoma,non-hodgkin lymphoma
6455	SH3GL1	SH3-domain GRB2-like 1	19p13.3	03462	10830	601768	NP_001186872;NP_001186873;NP_003016	NM_001199943;NM_001199944;NM_003025	ENSP00000470792;ENSP00000269886	known	1	0	3	Eukaryotes	18	1	Cellular processes,Development,Signal transduction	30	chr19	4361600	4400365	CGC	leukemia
54436	SH3TC1	SH3 domain and tetratricopeptide repeats 1	4p16.1	11556	26009	-	NP_061859	NM_018986	ENSP00000245105	candidate	0	0	0	Metazoans	17	0	-1	72	chr4	8206922	8242679	WES	colorectal
50944	SHANK1	SH3 and multiple ankyrin repeat domains 1	19q13.3	05413	15474	604999	NP_057232	NM_016148	ENSP00000293441	candidate	0	0	0	Last Universal Common Ancestor	20	1	Cellular processes	13	chr19	51165225	51220176	WES	colorectal,kidney
6464	SHC1	SHC (Src homology 2 domain containing) transforming protein 1	1q21	02780	10840	600560	NP_001123513;NP_001123512;NP_003020;NP_892113;NP_001189788	NM_001130041;NM_001130040;NM_003029;NM_183001;NM_001202859	ENSP00000401303;ENSP00000357435;ENSP00000357438;ENSP00000357430	known	0	0	1	Eukaryotes	295	8	Cell cycle,Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction	109	chr1	154936282	154943002	CGC,Amplified	
53358	SHC3	SHC (Src homology 2 domain containing) transforming protein 3	9q22.1	12005	18181	605263	NP_058544	NM_016848	-	candidate	0	0	0	Eukaryotes	18	4	Development,Signal transduction	14	chr9	91628365	91793375	WGS	lung
126669	SHE	Src homology 2 domain containing E	1q21.3	17293	27004	610482	NP_001010846	NM_001010846	ENSP00000307369	candidate	0	0	0	Eukaryotes	2	5	-1	-1	chr1	154456628	154474502	WGS	breast
6469	SHH	sonic hedgehog	7q36	02838	10848	600725	NP_000184	NM_000193	-	known	0	0	0	Eukaryotes	0	1	Cell cycle,Cell motility and interactions,Cell response to stimuli,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Immune system response,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	7	chr7	155595597	155604816	CGC,Amplified	
92799	SHKBP1	SH3KBP1 binding protein 1	19q13.2	15338	19214	-	NP_612401	NM_138392	ENSP00000291842	candidate	0	0	0	Eukaryotes	15	0	Cellular processes	-1	chr19	41082806	41097110	WES	acute myeloid leukemia
57619	SHROOM3	shroom family member 3	4q21.1	07053	30422	604570	NP_065910	NM_020859	ENSP00000296043	candidate	0	0	0	Metazoans	5	1	Cellular processes,Development,Regulation of intracellular processes and metabolism	-1	chr4	77357206	77700327	WES	gastric
6476	SI	sucrase-isomaltase (alpha-glucosidase)	3q25.2-q26.2	01962	10856	609845	NP_001032	NM_001041	ENSP00000264382	candidate	0	0	0	Last Universal Common Ancestor	1	1	-1	5	chr3	164697153	164793800	WES	chronic lymphocytic leukemia,head and neck squamous cell carcinoma
6614	SIGLEC1	sialic acid binding Ig-like lectin 1, sialoadhesin	20p13	02854	11127	600751	NP_075556	NM_023068	ENSP00000341141	candidate	0	0	0	Eukaryotes	3	0	Cell motility and interactions,Immune system response	89	chr20	3669210	3687775	WES	pancreas
89790	SIGLEC10	sialic acid binding Ig-like lectin 10	19q13.3	07307	15620	606091	NP_001164628;NP_001164631;NP_001164632;NP_001164627;NP_001164629;NP_149121;NP_001164630	NM_001171157;NM_001171160;NM_001171161;NM_001171156;NM_001171158;NM_033130;NM_001171159	ENSP00000342389;ENSP00000408387;ENSP00000396742;ENSP00000395475;ENSP00000348646	candidate	0	0	1	Eukaryotes	3	1	-1	-1	chr19	51914356	51920835	WGS	lymphoma
23387	SIK3	SIK family kinase 3	11q23.3	11121	29165	-	NP_079440	NM_025164	ENSP00000292055	candidate	0	0	0	Last Universal Common Ancestor	4	0	Cellular metabolism,Cellular processes	104	chr11	116717115	116968957	WES	breast
80143	SIKE1	suppressor of IKBKE 1	1p13.2	07958	26119	611656	NP_001095866;NP_079349	NM_001102396;NM_025073	ENSP00000358541	candidate	0	0	0	Eukaryotes	40	0	-1	80	chr1	115316895	115323228	WGS	chronic lymphocytic leukemia
51804	SIX4	SIX homeobox 4	14q23	06960	10890	606342	NP_059116	NM_017420	ENSP00000216513	candidate	0	0	0	Metazoans	24	8	Cell cycle,Cell motility and interactions,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription	-1	chr14	61180128	61190792	WES	breast
6502	SKP2	S-phase kinase-associated protein 2 (p45)	5p13	03256	10901	601436	NP_001230049;NP_116026;NP_005974	NM_001243120;NM_032637;NM_005983	ENSP00000274255;ENSP00000274254	known	0	0	0	Eukaryotes	117	2	Cell cycle	53	chr5	36152871	36182130	CGC,WES,Amplified	glioblastoma
6503	SLA	Src-like-adaptor	8q22.3-qter|8q24	03060	10902	601099	NP_006739;NP_001039021;NP_001039022	NM_006748;NM_001045556;NM_001045557	ENSP00000337548	candidate	0	0	0	Last Universal Common Ancestor	6	0	-1	95	chr8	134050772	134072525	WGS	liver
56996	SLC12A9	solute carrier family 12 (potassium/chloride transporters), member 9	7q22	11564	17435	-	NP_064631	NM_020246	ENSP00000443702;ENSP00000413796;ENSP00000275730	candidate	0	0	0	Last Universal Common Ancestor	2	0	-1	97	chr7	100451820	100464224	WGS	melanoma
6564	SLC15A1	solute carrier family 15 (oligopeptide transporter), member 1	13q33-q34	02768	10920	600544	NP_005064	NM_005073	-	candidate	0	0	0	Last Universal Common Ancestor	1	1	Cellular processes	37	chr13	99336981	99378703	WGS	acute myeloid leukemia
9122	SLC16A4	solute carrier family 16, member 4 (monocarboxylic acid transporter 5)	1p13.3	04855	10925	603878	NP_001188478;NP_001188477;NP_004687;NP_001188475;NP_001188476	NM_001201549;NM_001201548;NM_004696;NM_001201546;NM_001201547	ENSP00000432495;ENSP00000358796;ENSP00000358794	candidate	0	0	0	Eukaryotes	2	2	Cellular processes	7	chr1	110906391	110931945	WES	pancreas
26503	SLC17A5	solute carrier family 17 (anion/sugar transporter), member 5	6q14-q15	05058	10933	604322	NP_036566	NM_012434	ENSP00000348019	candidate	0	0	0	Last Universal Common Ancestor	2	7	Cellular processes	73	chr6	74304803	74363609	WES	melanoma
6511	SLC1A6	solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6	19p13.12	09005	10944	600637	NP_005062	NM_005071	ENSP00000221742	candidate	0	0	0	Last Universal Common Ancestor	1	1	Cellular processes,Multicellular activities	15	chr19	15061010	15083722	WES	pancreas
55356	SLC22A15	solute carrier family 22, member 15	1p13.1	-	20301	608275	NP_060890	NM_018420	ENSP00000358515	candidate	0	0	0	Last Universal Common Ancestor	0	1	Cellular processes	-1	chr1	116519249	116609726	WES	colorectal
57419	SLC24A3	solute carrier family 24 (sodium/potassium/calcium exchanger), member 3	20p13	15352	10977	609839	NP_065740	NM_020689	ENSP00000333519	candidate	0	0	0	Last Universal Common Ancestor	0	0	Cellular processes	52	chr20	19193487	19701781	WGS	melanoma
123041	SLC24A4	solute carrier family 24 (sodium/potassium/calcium exchanger), member 4	14q32.12	15353	10978	609840	NP_705933;NP_705932;NP_705934	NM_153647;NM_153646;NM_153648	-	candidate	0	0	0	Last Universal Common Ancestor	14	0	Cellular processes	-1	chr14	92790175	92959969	WGS	breast
55972	SLC25A40	solute carrier family 25, member 40	7q21.12	14372	29680	610821	NP_061331	NM_018843	-	candidate	0	0	0	Eukaryotes	0	3	-1	65	chr7	87465567	87488042	WGS	chronic lymphocytic leukemia
153328	SLC25A48	solute carrier family 25, member 48	5q31.1	14098	30451	-	NP_660325	NM_145282	ENSP00000413049	candidate	0	0	0	Eukaryotes	0	0	-1	-1	chr5	135170537	135223770	WES	lymphoma
2030	SLC29A1	solute carrier family 29 (nucleoside transporters), member 1	6p21.1	03724	11003	602193	NP_004946;NP_001071645;NP_001071643;NP_001071642;NP_001071644	NM_004955;NM_001078177;NM_001078175;NM_001078174;NM_001078176	ENSP00000377427;ENSP00000360805;ENSP00000360820;ENSP00000377424;ENSP00000392668	candidate	0	0	0	Eukaryotes	4	7	DNA/RNA metabolism and transcription	83	chr6	44197125	44201262	WES	colorectal
3177	SLC29A2	solute carrier family 29 (nucleoside transporters), member 2	11q13	03662	11004	602110	NP_001523	NM_001532	ENSP00000350024	candidate	0	0	0	Eukaryotes	2	0	DNA/RNA metabolism and transcription	22	chr11	66130910	66138798	WES	lymphoma
222962	SLC29A4	solute carrier family 29 (nucleoside transporters), member 4	7p22.1	15362	23097	609149	NP_694979;NP_001035751	NM_153247;NM_001040661	ENSP00000297195;ENSP00000380081	candidate	0	0	0	Eukaryotes	2	2	-1	-1	chr7	5327448	5342567	WGS	liver
114134	SLC2A13	solute carrier family 2 (facilitated glucose transporter), member 13	12q12	15363	15956	611036	NP_443117	NM_052885	ENSP00000280871	candidate	0	0	0	Last Universal Common Ancestor	0	1	Cellular processes	-1	chr12	40153831	40499610	WES	head and neck squamous cell carcinoma
29988	SLC2A8	solute carrier family 2 (facilitated glucose transporter), member 8	9q33.3	05580	13812	605245	NP_055395	NM_014580	ENSP00000362469	candidate	0	0	0	Last Universal Common Ancestor	1	0	Cellular processes	10	chr9	130159510	130169525	WGS	chronic lymphocytic leukemia
10568	SLC34A2	solute carrier family 34 (sodium phosphate), member 2	4p15.2	07251	11020	604217	NP_001171469;NP_001171470;NP_006415	NM_001177998;NM_001177999;NM_006424	ENSP00000371483	known	1	0	0	Last Universal Common Ancestor	0	2	Cellular metabolism,Cellular processes	42	chr4	25664123	25678368	CGC	lung
10991	SLC38A3	solute carrier family 38, member 3	3p21.3	11980	18044	604437	NP_006832	NM_006841	-	candidate	0	0	0	-	5	0	Cellular processes	37	chr3	50251633	50257606	HTMS	lung
146167	SLC38A8	solute carrier family 38, member 8	16q23.3	-	32434	-	NP_001073911	NM_001080442	ENSP00000299709	candidate	0	0	0	Last Universal Common Ancestor	0	0	Cellular processes	-1	chr16	84043392	84075762	WES	lymphoma
57181	SLC39A10	solute carrier family 39 (zinc transporter), member 10	2q32.3	10572	20861	608733	NP_001120729;NP_065075	NM_001127257;NM_020342	ENSP00000386766;ENSP00000352655	candidate	0	0	0	Last Universal Common Ancestor	2	7	Cellular processes	-1	chr2	196544767	196599762	WGS	melanoma
23446	SLC44A1	solute carrier family 44, member 1	9q31.2	16197	18798	606105	NP_536856	NM_080546;NM_022109	-	candidate	0	0	0	Eukaryotes	7	9	Cellular processes	18	chr9	108061501	108147783	WGS	breast
51151	SLC45A2	solute carrier family 45, member 2	5p13.2	05865	16472	606202	NP_057264;NP_001012527	NM_016180;NM_001012509	ENSP00000371534;ENSP00000296589	candidate	0	0	0	Last Universal Common Ancestor	0	0	Cell response to stimuli,Cellular metabolism	43	chr5	33944756	33984688	WGS	chronic lymphocytic leukemia
85414	SLC45A3	solute carrier family 45, member 3	1q32.1	16312	8642	605097	NP_149093	NM_033102	ENSP00000356113	known	1	0	0	Eukaryotes	2	2	-1	-1	chr1	205628365	205633784	CGC	prostate
57282	SLC4A10	solute carrier family 4, sodium bicarbonate transporter, member 10	2q23-q24	-	13811	605556	NP_001171486;NP_001171487;NP_071341	NM_001178015;NM_001178016;NM_022058	ENSP00000393066;ENSP00000364664;ENSP00000395797	candidate	0	0	0	Eukaryotes	3	1	Cellular processes	18	chr2	162481029	162833384	WES	chronic lymphocytic leukemia
6538	SLC6A11	solute carrier family 6 (neurotransmitter transporter, GABA), member 11	3p25.3	06406	11044	607952	NP_055044	NM_014229	-	candidate	0	0	0	Last Universal Common Ancestor	0	0	Cellular processes	1	chr3	10857951	10980085	WES	melanoma
55117	SLC6A15	solute carrier family 6 (neutral amino acid transporter), member 15	12q21.3	12141	13621	607971	NP_877499;NP_060527;NP_001139807	NM_182767;NM_018057;NM_001146335	ENSP00000390706;ENSP00000266682	candidate	0	0	0	Last Universal Common Ancestor	2	0	Cellular processes	9	chr12	85255414	85285899	WES	pancreas
388662	SLC6A17	solute carrier family 6, member 17	1p13.3	18061	31399	610299	NP_001010898	NM_001010898	ENSP00000405461	candidate	0	0	0	Last Universal Common Ancestor	1	0	Cellular processes	-1	chr1	110709552	110741063	WGS	prostate
6530	SLC6A2	solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2	16q12.2	01232	11048	163970	NP_001165975;NP_001165972;NP_001034;NP_001165973	NM_001172504;NM_001172501;NM_001043;NM_001172502	ENSP00000369237;ENSP00000394956;ENSP00000457375;ENSP00000219833	candidate	0	0	0	Last Universal Common Ancestor	5	0	Cell response to stimuli,Cellular processes,Multicellular activities	41	chr16	55690607	55739181	HTMS	breast,lung,ovarian,pancreas,prostate
6531	SLC6A3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3	5p15.3	00543	11049	126455	NP_001035	NM_001044	ENSP00000270349	candidate	0	0	0	Last Universal Common Ancestor	16	0	Cell cycle,Cell response to stimuli,Cellular metabolism,Cellular processes,Development,Immune system response,Multicellular activities,Regulation of intracellular processes and metabolism	32	chr5	1401024	1443312	WES	breast
57709	SLC7A14	solute carrier family 7 (orphan transporter), member 14	3q26.2	17222	29326	-	NP_066000	NM_020949;NM_175917	-	candidate	0	0	0	Last Universal Common Ancestor	1	0	Cellular processes	-1	chr3	170184846	170244725	WGS	liver
6543	SLC8A2	solute carrier family 8 (sodium/calcium exchanger), member 2	19q13.3	15990	11069	601901	NP_055878	NM_015063	ENSP00000236877	candidate	0	0	2	Eukaryotes	5	0	Cellular processes	34	chr19	47933349	47969660	WES	melanoma
6547	SLC8A3	solute carrier family 8 (sodium/calcium exchanger), member 3	14q24.1	09723	11070	607991	NP_489479;NP_891981;NP_892114;NP_150287;NP_001123889;NP_891977	NM_058240;NM_182936;NM_183002;NM_033262;NM_001130417;NM_182933;NM_182932	ENSP00000216568;ENSP00000350560;ENSP00000349392;ENSP00000377863;ENSP00000370669	candidate	0	0	2	Eukaryotes	4	0	Cellular processes	-1	chr14	70512667	70635139	WES	breast
285335	SLC9A10	solute carrier family 9, member 10	3q13.2	11257	31401	612738	NP_898884	NM_183061	ENSP00000306627	candidate	0	0	0	Eukaryotes	2	0	Cellular processes,Development,Multicellular activities	-1	chr3	111870703	112005638	WES	breast
10599	SLCO1B1	solute carrier organic anion transporter family, member 1B1	12p	09214	10959	604843	NP_006437	NM_006446	ENSP00000256958	candidate	0	0	2	Metazoans	0	2	Cellular processes	2	chr12	21294509	21392120	WES	chronic lymphocytic leukemia,melanoma
28234	SLCO1B3	solute carrier organic anion transporter family, member 1B3	12p12	12021	10961	605495	NP_062818	NM_019844	ENSP00000370956	candidate	0	0	2	Metazoans	0	0	Cellular processes	2	chr12	20968673	21069178	WGS	lymphoma
9353	SLIT2	slit homolog 2 (Drosophila)	4p15.2	04776	11086	603746	NP_004778	NM_004787	ENSP00000427548	candidate	0	0	0	Last Universal Common Ancestor	8	0	Cell cycle,Cell motility and interactions,Cell response to stimuli,Development,Immune system response,Multicellular activities,Regulation of intracellular processes and metabolism,Signal transduction	74	chr4	20255439	20620629	WES	lung
22865	SLITRK3	SLIT and NTRK-like family, member 3	3q26.1	18064	23501	609679	NP_055741	NM_014926	ENSP00000241274	candidate	0	0	0	Eukaryotes	2	0	Cell cycle,Development	35	chr3	164905688	164908618	WES	head and neck squamous cell carcinoma
26050	SLITRK5	SLIT and NTRK-like family, member 5	13q31.2	18065	20295	609680	NP_056382	NM_015567	ENSP00000366283	candidate	0	0	0	Eukaryotes	0	0	-1	18	chr13	88327644	88330517	WES	pancreas
84189	SLITRK6	SLIT and NTRK-like family, member 6	13q31.1	15403	23503	609681	NP_115605	NM_032229	ENSP00000383143	candidate	0	0	0	Eukaryotes	3	0	-1	-1	chr13	86368121	86370643	WES	lymphoma
57152	SLURP1	secreted LY6/PLAUR domain containing 1	8q24.3	05836	18746	606119	NP_065160	NM_020427	ENSP00000246515	candidate	0	0	0	Mammals	0	0	-1	11	chr8	143822564	143823803	WES	lung
4087	SMAD2	SMAD family member 2	18q21.1	03221	6768	601366	NP_001129409;NP_005892;NP_001003652	NM_001135937;NM_005901;NM_001003652	ENSP00000384449;ENSP00000349282;ENSP00000262160	candidate	0	0	1	Metazoans	418	3	Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	106	chr18	45368201	45423127	WES	colorectal,colorectal (non-hypermutated)
4088	SMAD3	SMAD family member 3	15q22.33	08533	6769	603109	NP_001138576;NP_005893;NP_001138574;NP_001138575	NM_001145104;NM_005902;NM_001145102;NM_001145103	ENSP00000332973	candidate	0	0	1	Metazoans	417	3	Cell cycle,Cell motility and interactions,Cell response to stimuli,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Other,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	100	chr15	67358493	67482871	WES	colorectal
4089	SMAD4	SMAD family member 4	18q21.1	02995	6770	600993	NP_005350	NM_005359	ENSP00000341551	known	0	1	0	Metazoans	241	19	Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	73	chr18	48573417	48604834	CGC,WES	colorectal,pancreas,small intestine ,breast,cholangiocarcinoma,colorectal (non-hypermutated),lung
6594	SMARCA1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1	Xq25	02055	11097	300012	NP_003060;NP_620604	NM_003069;NM_139035	ENSP00000360163;ENSP00000360162	candidate	0	0	1	Last Universal Common Ancestor	19	8	Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription	90	chrX	128582289	128657347	WES	lymphoma
6597	SMARCA4	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4	19p13.2	04459	11100	603254	NP_001122321;NP_001122316;NP_001122318;NP_001122317;NP_001122319;NP_001122320;NP_003063	NM_001128849;NM_001128844;NM_001128846;NM_001128845;NM_001128847;NM_001128848;NM_003072	ENSP00000395654;ENSP00000414727;ENSP00000397783;ENSP00000466963;ENSP00000392837;ENSP00000350720;ENSP00000343896	known	0	1	0	Last Universal Common Ancestor	210	4	Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription	105	chr19	11094828	11170875	CGC,WES,WGS	lung,lymphoma,medulloblastoma,pancreas
56916	SMARCAD1	SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1	4q22-q23	11586	18398	612761	NP_001241878;NP_064544;NP_001121902;NP_001121901	NM_001254949;NR_045644;NM_020159;NM_001128430;NM_001128429	ENSP00000415576;ENSP00000351947;ENSP00000346217	candidate	0	0	0	Last Universal Common Ancestor	118	3	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	-1	chr4	95129546	95210682	WGS	melanoma
6598	SMARCB1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1	22q11.23|22q11	03364	11103	601607	NP_003064;NP_001007469	NM_003073;NM_001007468	ENSP00000383984;ENSP00000263121	known	0	1	0	Eukaryotes	120	4	Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Other,Regulation of intracellular processes and metabolism,Regulation of transcription	104	chr22	24129357	24176364	CGC,WES	malignant rhabdoid ,melanoma
6602	SMARCD1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1	12q13-q14	03438	11106	601735	NP_003067;NP_620710	NM_003076;NM_139071	ENSP00000378414;ENSP00000370924	candidate	0	0	0	Last Universal Common Ancestor	37	6	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	82	chr12	50479153	50492780	WES	breast
10592	SMC2	structural maintenance of chromosomes 2	9q31.1	09277	14011	605576	NP_001036015;NP_006435;NP_001036016	NM_001042550;NM_006444;NM_001042551	ENSP00000286398;ENSP00000363925	candidate	0	0	0	Last Universal Common Ancestor	44	2	Cell cycle,DNA/RNA metabolism and transcription	47	chr9	106857666	106901593	WGS	chronic lymphocytic leukemia
9126	SMC3	structural maintenance of chromosomes 3	10q25	05829	2468	606062	NP_005436	NM_005445	ENSP00000354720	candidate	0	0	0	Last Universal Common Ancestor	24	3	Cell cycle,Cellular processes,DNA/RNA metabolism and transcription,Signal transduction	81	chr10	112328696	112364057	WGS	glioblastoma
23381	SMG5	smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans)	1q21.2	16869	24644	610962	NP_056142	NM_015327	ENSP00000355261	candidate	0	0	0	Eukaryotes	6	0	Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	44	chr1	156220381	156252471	WGS	melanoma
6608	SMO	smoothened, frizzled family receptor	7q32.3	03294	11119	601500	NP_005622	NM_005631	ENSP00000249373	known	1	0	0	Metazoans	1	5	Cell cycle,Cell motility and interactions,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Signal transduction	48	chr7	128828993	128852289	CGC	skin
6525	SMTN	smoothelin	22q12.2	03675	11126	602127	NP_599032;NP_001193947;NP_008863;NP_599031;NP_001193946	NM_134270;NM_001207018;NM_006932;NM_134269;NM_001207017	ENSP00000328635;ENSP00000329532;ENSP00000351593	candidate	0	0	0	Metazoans	9	0	Development,Multicellular activities	65	chr22	31479164	31500449	WES	colorectal
57154	SMURF1	SMAD specific E3 ubiquitin protein ligase 1	7q22.1	06902	16807	605568	NP_065162;NP_001186776;NP_851994	NM_020429;NM_001199847;NM_181349	ENSP00000354621;ENSP00000355326	known	0	0	1	Eukaryotes	126	0	Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction	89	chr7	98628210	98741403	CGC,Amplified	
64750	SMURF2	SMAD specific E3 ubiquitin protein ligase 2	17q22-q23	06901	16809	605532	NP_073576	NM_022739	-	candidate	0	0	1	Eukaryotes	140	3	Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	77	chr17	62541969	62657998	WES	melanoma
25992	SNED1	sushi, nidogen and EGF-like domains 1	2q37.3	-	24696	-	NP_001073906	NM_001080437	ENSP00000308893	candidate	0	0	0	Last Universal Common Ancestor	2	1	Cell motility and interactions	65	chr2	241938255	242026891	WGS	breast
6626	SNRPA	small nuclear ribonucleoprotein polypeptide A	19q13.1	01658	11151	182285	NP_004587	NM_004596	ENSP00000243563	candidate	0	0	0	Eukaryotes	66	0	DNA/RNA metabolism and transcription,Regulation of transcription	90	chr19	41257314	41271069	WES	melanoma
92017	SNX29	sorting nexin 29	16p13.13-p13.12	17437	30542	-	NP_115543;NP_001073999	NM_032167;NM_001009607;NM_001080530	ENSP00000456480	known	1	0	0	Eukaryotes	1	1	-1	4	chr16	12093153	12662483	CGC	lymphoma
8723	SNX4	sorting nexin 4	3q21.2	09334	11175	605931	NP_003785	NM_003794	ENSP00000251775	candidate	0	0	0	Eukaryotes	20	2	Cellular processes	96	chr3	125166626	125239016	WGS	breast
51375	SNX7	sorting nexin 7	1p21.3	15416	14971	-	NP_689424;NP_057060	NM_152238;NR_033716;NM_015976	ENSP00000304429;ENSP00000434731	candidate	0	0	1	Eukaryotes	13	7	Cellular processes	70	chr1	99127288	99225684	WES,WGS	chronic lymphocytic leukemia
8651	SOCS1	suppressor of cytokine signaling 1	16p13.13	04669	19383	603597	NP_003736	NM_003745	ENSP00000329418	known	0	1	0	Vertebrates	7	7	Cell cycle,Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction	43	chr16	11348703	11349335	CGC,WES	lymphoma
6651	SON	SON DNA binding protein	21q22.1-q22.2|21q22.11	01678	11183	182465	NP_620305;NP_115571	NM_003103;NM_138925;NM_138926;NM_138927;NM_032195;NM_058183	ENSP00000300278;ENSP00000348984	candidate	0	0	0	Last Universal Common Ancestor	55	10	Cell cycle,Development,Regulation of intracellular processes and metabolism	109	chr21	34915399	34948727	WES	pancreas
114815	SORCS1	sortilin-related VPS10 domain containing receptor 1	10q23-q25	12098	16697	606283	NP_001193499;NP_443150;NP_001013049;NP_001193500;NP_001193498;NP_001193501	NM_001206570;NM_052918;NM_001013031;NM_001206571;NM_001206569;NM_001206572	ENSP00000345964	candidate	0	0	0	Eukaryotes	2	0	Signal transduction	-1	chr10	108336982	108924284	WES	pancreas
6653	SORL1	sortilin-related receptor, L(DLR class) A repeats containing	11q23.2-q24.2	03595	11185	602005	NP_003096	NM_003105	ENSP00000260197	candidate	0	0	0	Eukaryotes	14	0	Cellular metabolism,Cellular processes	106	chr11	121323041	121500269	WES	breast,colorectal
6654	SOS1	son of sevenless homolog 1 (Drosophila)	2p21	01681	11187	182530	NP_005624	NM_005633	ENSP00000384675	candidate	0	0	0	Eukaryotes	86	0	Signal transduction	85	chr2	39212968	39347563	HTMS	breast,lung,ovarian,pancreas,prostate
6665	SOX15	SRY (sex determining region Y)-box 15	17p12.3	03191	11196	601297	NP_008873	NM_006942	ENSP00000355354	candidate	0	0	0	Eukaryotes	1	0	Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription	65	chr17	7491699	7492994	WGS	lymphoma
6657	SOX2	SRY (sex determining region Y)-box 2	3q26.3-q27	08921	11195	184429	NP_003097	NM_003106	ENSP00000323588	known	1	0	0	Eukaryotes	0	6	Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription	61	chr3	181430149	181431099	CGC	lung,oesophageal
6660	SOX5	SRY (sex determining region Y)-box 5	12p12.1	18086	11201	604975	NP_821078;NP_694534;NP_008871	NM_178010;NM_152989;NM_006940	ENSP00000370788;ENSP00000398273;ENSP00000308927	candidate	0	0	0	Eukaryotes	11	5	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	31	chr12	23687156	24102535	WES	pancreas
30812	SOX8	SRY (sex determining region Y)-box 8	16p13.3	16175	11203	605923	NP_055402	NM_014587	ENSP00000293894	candidate	0	0	0	Eukaryotes	4	0	Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription	-1	chr16	1031923	1035383	WGS	lymphoma
6662	SOX9	SRY (sex determining region Y)-box 9	17q23	06427	11204	608160	NP_000337	NM_000346	ENSP00000245479	candidate	0	0	0	Eukaryotes	1	6	Cell cycle,Cell motility and interactions,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription	79	chr17	70117533	70120525	WES	colorectal (non-hypermutated)
6667	SP1	Sp1 transcription factor	12q13.1	01796	11205	189906	NP_612482;NP_003100;NP_001238754	NM_138473;NM_003109;NM_001251825	ENSP00000404263	candidate	0	0	0	Last Universal Common Ancestor	282	17	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	10	chr12	53775442	53805021	WGS	breast
3431	SP110	SP110 nuclear body protein	2q37.1	06832	5401	604457	NP_001171944;NP_004500;NP_536349;NP_004501	NM_001185015;NM_004509;NM_080424;NM_004510	ENSP00000439558;ENSP00000351488;ENSP00000258382;ENSP00000258381	candidate	0	0	0	Eukaryotes	18	1	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	106	chr2	231033843	231081642	WES	breast
6674	SPAG1	sperm associated antigen 1	8q22.2	04548	11212	603395	NP_757367;NP_003105	NM_172218;NM_003114	ENSP00000373450;ENSP00000251809	candidate	0	0	0	Last Universal Common Ancestor	5	4	Development	38	chr8	101174509	101253247	WGS	melanoma
200162	SPAG17	sperm associated antigen 17	1p12	10146	26620	-	NP_996879	NM_206996	ENSP00000337804	candidate	0	0	0	Eukaryotes	56	0	-1	-1	chr1	118506425	118727780	WES,WGS	liver,prostate
494119	SPANXN2	SPANX family, member N2	Xq27.3	18091	33175	300665	NP_001009615	NM_001009615	ENSP00000359529	candidate	0	0	3	Opisthokonts	0	0	-1	-1	chrX	142795138	142803762	WES	gastric
221178	SPATA13	spermatogenesis associated 13	13q12.12	15427	23222	613324	NP_694568;NP_001159743	NM_153023;NM_001166271	ENSP00000371542;ENSP00000371527	candidate	0	0	0	Eukaryotes	1	2	Signal transduction	-1	chr13	24797068	24876908	WGS	melanoma
132671	SPATA18	spermatogenesis associated 18	4q12	14050	29579	612814	NP_660306	NM_145263	ENSP00000295213	candidate	0	0	0	Metazoans	0	1	Development,Multicellular activities	-1	chr4	52917871	52960737	WGS	chronic lymphocytic leukemia
55812	SPATA7	spermatogenesis associated 7	14q31.3	15431	20423	609868	NP_001035518;NP_060888	NM_001040428;NM_018418	ENSP00000348991;ENSP00000377176	candidate	0	0	0	Metazoans	1	0	-1	22	chr14	88857724	88904763	WGS	glioblastoma
25803	SPDEF	SAM pointed domain containing ets transcription factor	6p21.3	12176	17257	608144	NP_036523;NP_001239223	NM_012391;NM_001252294	ENSP00000442715;ENSP00000363149	candidate	0	0	0	Metazoans	4	3	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	64	chr6	34506054	34512232	WGS	melanoma
92521	SPECC1	sperm antigen with calponin homology and coiled-coil domains 1	17p11.2	12301	30615	608793	NP_001230368;NP_001028725;NP_001028727;NP_690868;NP_001230367;NP_001028726	NM_001243439;NM_001033553;NM_001033555;NM_152904;NM_001243438;NM_001033554	ENSP00000261503;ENSP00000378898;ENSP00000378900	known	1	0	0	Metazoans	5	1	-1	-1	chr17	19999965	20217375	CGC,WES	leukemia,lymphoma
80309	SPHKAP	SPHK1 interactor, AKAP domain containing	2q36	18052	30619	611646	NP_001136116;NP_085126	NM_001142644;NM_030623	ENSP00000375909;ENSP00000339886	candidate	0	0	0	Vertebrates	1	0	-1	-1	chr2	228846436	228996803	WES	lung
391253	SPINT4	serine peptidase inhibitor, Kunitz type 4	20q13.12	-	16130	-	NP_848550	NM_178455	-	candidate	0	0	0	Eukaryotes	0	1	-1	-1	chr20	44351007	44352697	WGS	lung
23626	SPO11	SPO11 meiotic protein covalently bound to DSB homolog (S. cerevisiae)	20q13.31	09236	11250	605114	NP_937998;NP_036576	NM_198265;NM_012444	ENSP00000360310;ENSP00000316034	candidate	0	0	0	Last Universal Common Ancestor	0	1	Cell cycle,DNA/RNA metabolism and transcription,Development,Multicellular activities	16	chr20	55904924	55918513	WGS	melanoma
8405	SPOP	speckle-type POZ protein	17q21.33	16004	11254	602650	NP_001007227;NP_001007228;NP_003554;NP_001007229;NP_001007230;NP_001007231	NM_001007226;NM_001007227;NM_003563;NM_001007228;NM_001007229;NM_001007230	ENSP00000377004;ENSP00000240327;ENSP00000377001	candidate	0	0	1	Eukaryotes	38	0	DNA/RNA metabolism and transcription,Regulation of transcription	106	chr17	47677743	47700172	HTMS,WES,WGS	breast,lung,ovarian,pancreas,prostate,endometrium
6701	SPRR2B	small proline-rich protein 2B	1q21-q22	-	11262	182268	NP_001017418	NM_001017418	ENSP00000340703	candidate	0	0	6	Primates	0	0	Development	19	chr1	153043100	153043315	WES	gastric
10251	SPRY3	sprouty homolog 3 (Drosophila)	Xq28 and Yq12	03917	11271	300531	NP_005831	NM_005840	ENSP00000302978	candidate	0	0	1	Eukaryotes	1	0	Signal transduction	-1	chrX	155003534	155004397	WES	chronic lymphocytic leukemia
6708	SPTA1	spectrin, alpha, erythrocytic 1 (elliptocytosis 2)	1q21	01685	11272	182860	NP_003117	NM_003126	ENSP00000357130	candidate	0	0	0	Eukaryotes	30	3	Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism	54	chr1	158581057	158655137	WES,WGS	gastric,melanoma,prostate
6709	SPTAN1	spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)	9q34.11	01684	11273	182810	NP_003118;NP_001182461;NP_001123910	NM_003127;NM_001195532;NM_001130438	ENSP00000361824;ENSP00000361816	candidate	0	0	0	Last Universal Common Ancestor	131	1	Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism	99	chr9	131329020	131395610	WES	breast
6710	SPTB	spectrin, beta, erythrocytic	14q23-q24.2	01686	11274	182870	NP_001020029;NP_000338	NM_001024858;NM_000347	ENSP00000374371;ENSP00000374372	candidate	0	0	0	Eukaryotes	20	1	Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism	45	chr14	65216027	65289812	WGS	lung
57731	SPTBN4	spectrin, beta, non-erythrocytic 4	19q13.13	09372	14896	606214	NP_079489;NP_066022	NM_025213;NM_020971	ENSP00000469242;ENSP00000375877	candidate	0	0	0	Eukaryotes	20	0	Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism	31	chr19	40978529	41081472	WES	kidney
9901	SRGAP3	SLIT-ROBO Rho GTPase activating protein 3	3p25.3	12108	19744	606525	NP_055665;NP_001028289	NM_014850;NM_001033117;NM_001033116	ENSP00000353587;ENSP00000373347	known	1	0	0	Eukaryotes	9	0	Signal transduction	54	chr3	9027206	9290635	CGC,WGS	pilocytic astrocytoma,prostate
8406	SRPX	sushi-repeat containing protein, X-linked	Xp21.1	02175	11309	300187	NP_001164221;NP_001164222;NP_006298;NP_001164223	NM_001170750;NM_001170751;NM_006307;NM_001170752	ENSP00000440758;ENSP00000411165;ENSP00000445034;ENSP00000367794	candidate	0	0	0	Eukaryotes	4	1	-1	94	chrX	38008967	38037598	WES	lymphoma
10250	SRRM1	serine/arginine repetitive matrix 1	1p36.11	10441	16638	605975	NP_005830	NM_005839	ENSP00000326261	candidate	0	0	1	Eukaryotes	123	2	DNA/RNA metabolism and transcription,Regulation of transcription	109	chr1	24972475	24998774	WGS	acute myeloid leukemia
6426	SRSF1	serine/arginine-rich splicing factor 1	17q22	02887	10780	600812	NP_001071634;NP_008855	NR_034041;NM_001078166;NM_006924	-	candidate	0	0	0	Last Universal Common Ancestor	145	10	DNA/RNA metabolism and transcription,Regulation of transcription	109	chr17	56082770	56084498	WES	chronic lymphocytic leukemia
9295	SRSF11	serine/arginine-rich splicing factor 11	1p31	03599	10782	602010	NP_001177916;NP_004759	NM_001190987;NM_004768	ENSP00000359989	candidate	0	0	0	Eukaryotes	60	3	DNA/RNA metabolism and transcription,Regulation of transcription	106	chr1	70687320	70716485	WGS	prostate
6427	SRSF2	serine/arginine-rich splicing factor 2	17q25.1	02888	10783	600813	NP_001182356;NP_003007	NM_001195427;NR_036608;NM_003016	ENSP00000353089;ENSP00000376276	known	1	0	1	Eukaryotes	92	6	DNA/RNA metabolism and transcription,Regulation of transcription	109	chr17	74732246	74733242	CGC,WES	leukemia,myelodysplasia
6428	SRSF3	serine/arginine-rich splicing factor 3	6p21	04530	10785	603364	NP_003008	NM_003017;NR_036610	-	known	1	0	4	Eukaryotes	113	2	DNA/RNA metabolism and transcription,Regulation of transcription	109	chr11	18686597	18687095	CGC	lymphoma
6431	SRSF6	serine/arginine-rich splicing factor 6	20q12-q13.1	09054	10788	601944	NP_006266	NM_006275;NR_034009	ENSP00000244020	candidate	0	0	1	Last Universal Common Ancestor	35	4	DNA/RNA metabolism and transcription,Regulation of transcription	108	chr20	42086674	42089700	WES	colorectal
6760	SS18	synovial sarcoma translocation, chromosome 18	18q11.2	02559	11340	600192	NP_005628;NP_001007560	NM_005637;NM_001007559	ENSP00000414516	known	1	0	0	Eukaryotes	21	3	-1	78	chr18	23612363	23670533	CGC	sarcoma
26039	SS18L1	synovial sarcoma translocation gene on chromosome 18-like 1	20q13.3	09398	15592	606472	NP_945173	NM_015558;NM_198935	ENSP00000333012	known	1	0	0	Eukaryotes	28	0	-1	65	chr20	60718877	60749700	CGC,WGS	sarcoma,lymphoma
6741	SSB	Sjogren syndrome antigen B (autoantigen La)	2q31.1	00168	11316	109090	NP_003133	NM_003142	ENSP00000260956	candidate	0	0	4	Eukaryotes	26	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of transcription	86	chr2	170657471	170668263	WES	melanoma
54961	SSH3	slingshot homolog 3 (Drosophila)	11q13.2	09488	30581	606780	NP_060327	NM_018276;NM_017857	ENSP00000312081	candidate	0	0	0	Last Universal Common Ancestor	5	1	Cellular metabolism,Cellular processes	80	chr11	67071097	67079355	WGS	melanoma
6756	SSX1	synovial sarcoma, X breakpoint 1	Xp11.23	02428	11335	312820	NP_005626	NM_005635	ENSP00000366118	known	1	0	2	Eukaryotes	2	3	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	34	chrX	48116677	48125819	CGC	sarcoma
6757	SSX2	synovial sarcoma, X breakpoint 2	Xp11.22	02180	11336	300192	NP_003138;NP_783629	NM_003147;NM_175698	ENSP00000338796;ENSP00000338561	known	1	0	2	Eukaryotes	4	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	6	chrX	52727082	52734799	CGC	sarcoma
6759	SSX4	synovial sarcoma, X breakpoint 4	Xp11.23	02266	11338	300326	NP_005627;NP_783856	NM_005636;NM_175729	ENSP00000366083	known	1	0	3	Eukaryotes	4	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	1	chrX	48262901	48270814	CGC	sarcoma
84620	ST6GAL2	ST6 beta-galactosamide alpha-2,6-sialyltranferase 2	2q11.2-q12.1	12237	10861	608472	NP_001135823;NP_115917;NP_001135824	NM_001142351;NM_032528;NM_001142352	ENSP00000386942;ENSP00000387332;ENSP00000355273	candidate	0	0	0	Eukaryotes	1	0	Cellular metabolism,Cellular processes	-1	chr2	107423137	107460433	WES	pancreas
256435	ST6GALNAC3	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3	1p31.1	15341	19343	610133	NP_001153483;NP_694541	NM_001160011;NM_152996	-	candidate	0	0	0	Eukaryotes	0	0	Cellular metabolism,Cellular processes	-1	chr1	76779484	77094488	WES	melanoma
23166	STAB1	stabilin 1	3p21.1	09778	18628	608560	NP_055951	NM_015136	ENSP00000312946	candidate	0	0	0	Last Universal Common Ancestor	2	0	Cell response to stimuli,Cellular processes,Development,Immune system response	90	chr3	52529430	52558369	WES	colorectal
10948	STARD3	StAR-related lipid transfer (START) domain containing 3	17q11-q12	06132	17579	607048	NP_001159410;NP_001159409;NP_006795	NM_001165938;NM_001165937;NM_006804	-	known	0	0	0	Eukaryotes	0	0	Cellular metabolism,Cellular processes	48	chr17	37809785	37819158	CGC,Amplified	
9754	STARD8	StAR-related lipid transfer (START) domain containing 8	Xq13.1	06730	19161	300689	NP_055540;NP_001135975;NP_001135976	NM_014725;NM_001142503;NM_001142504	ENSP00000363727;ENSP00000363725;ENSP00000252336	candidate	0	0	0	Eukaryotes	0	0	Signal transduction	60	chrX	67867725	67944261	WES	breast
6774	STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)	17q21.31	00026	11364	102582	NP_644805;NP_003141;NP_998827	NM_139276;NM_003150;NM_213662	ENSP00000264657	candidate	0	0	0	Eukaryotes	206	7	Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	108	chr17	40467766	40500534	WES	lymphoma
6775	STAT4	signal transducer and activator of transcription 4	2q32.2-q32.3	02779	11365	600558	NP_001230764;NP_003142	NM_001243835;NM_003151	ENSP00000351255;ENSP00000376134	candidate	0	0	0	Eukaryotes	2	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	69	chr2	191895683	192012929	WES	melanoma
6778	STAT6	signal transducer and activator of transcription 6, interleukin-4 induced	12q13	03302	11368	601512	NP_001171552;NP_001171550;NP_003144;NP_001171551;NP_001171549	NM_001178081;NM_001178079;NM_003153;NM_001178080;NR_033659;NM_001178078	ENSP00000300134	candidate	0	0	0	Eukaryotes	59	2	Cell cycle,Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Immune system response,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	102	chr12	57490358	57502061	WES	lymphoma
6781	STC1	stanniocalcin 1	8p21-p11.2	03115	11373	601185	NP_003146	NM_003155	ENSP00000290271	candidate	0	0	0	Metazoans	0	0	Cell response to stimuli,Regulation of intracellular processes and metabolism,Signal transduction	66	chr8	23702286	23712036	WES	melanoma
6491	STIL	SCL/TAL1 interrupting locus	1q32|1p32	01627	10879	181590	NP_003026;NP_001041631	NM_003035;NM_001048166	ENSP00000360944;ENSP00000337367	known	1	0	0	Eukaryotes	1	3	-1	44	chr1	47716811	47775991	CGC	leukemia
10963	STIP1	stress-induced-phosphoprotein 1	11q13	05454	11387	605063	NP_006810	NM_006819	ENSP00000305958	candidate	0	0	1	Last Universal Common Ancestor	21	2	-1	58	chr11	63960547	63971595	WGS	liver
6794	STK11	serine/threonine kinase 11	19p13.3	03740	11389	602216	NP_000446	NM_000455	ENSP00000324856	known	0	1	0	Last Universal Common Ancestor	59	2	Cell cycle,Cellular metabolism,Cellular processes	73	chr19	1206913	1226643	CGC,HTMS,WES	lung,pancreas,breast,ovarian,prostate
8859	STK19	serine/threonine kinase 19	6p21.3	07281	11398	604977	NP_115830;NP_004188	NM_032454;NR_026717;NM_004197	ENSP00000364480;ENSP00000364482	candidate	0	0	0	Eukaryotes	13	0	Cellular metabolism,Cellular processes	107	chr6	31939774	31981561	WGS	melanoma
7955	STL	six-twelve leukemia	6q22.33	-	-	602532	-	NR_026876	-	known	1	0	-1	-	0	0	-1	-1	-	0	0	CGC	leukemia
64220	STRA6	stimulated by retinoic acid gene 6 homolog (mouse)	15q24.1	18122	30650	610745	NP_071764;NP_001136091;NP_001185969;NP_001136089;NP_001185970;NP_001136092;NP_001185971;NP_001136090	NM_022369;NM_001142619;NM_001199040;NM_001142617;NM_001199041;NM_001142620;NM_001199042;NM_001142618	ENSP00000326085;ENSP00000413012;ENSP00000407176;ENSP00000440238;ENSP00000458827;ENSP00000456609;ENSP00000378537	candidate	0	0	0	Eukaryotes	0	0	-1	61	chr15	74472424	74494860	WGS	melanoma
55359	STYK1	serine/threonine/tyrosine kinase 1	12p13.2	15447	18889	611433	NP_060893	NM_018423	ENSP00000075503	candidate	0	0	0	Last Universal Common Ancestor	2	0	Cellular metabolism,Cellular processes	63	chr12	10772746	10787217	WES	head and neck squamous cell carcinoma
51684	SUFU	suppressor of fused homolog (Drosophila)	10q24.32	06124	16466	607035	NP_057253;NP_001171604	NM_016169;NM_001178133	ENSP00000358915;ENSP00000358918	known	0	1	0	Last Universal Common Ancestor	38	1	Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	-1	chr10	104263910	104389909	CGC	medulloblastoma
55959	SULF2	sulfatase 2	20q12-q13.2	18130	20392	610013	NP_061325;NP_940998;NP_001155313	NM_018837;NM_198596;NM_001161841	ENSP00000418290;ENSP00000418442	candidate	0	0	0	Last Universal Common Ancestor	1	1	Cellular metabolism	-1	chr20	46288142	46386107	WES	breast
56241	SUSD2	sushi domain containing 2	22q11-q12	18132	30667	-	NP_062547	NM_019601	ENSP00000351075	candidate	0	0	0	Eukaryotes	3	0	-1	-1	chr22	24577488	24584296	WGS	lymphoma
203328	SUSD3	sushi domain containing 3	9q22.31	15453	28391	-	NP_659443	NM_145006	ENSP00000364621	candidate	0	0	0	Vertebrates	1	1	-1	-1	chr9	95821025	95847026	WGS	lung
23512	SUZ12	suppressor of zeste 12 homolog (Drosophila)	17q11.2	06949	17101	606245	NP_056170	NM_015355	ENSP00000316578	known	1	0	0	Eukaryotes	13	7	Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	100	chr17	30264266	30326019	CGC	endometrium
6850	SYK	spleen tyrosine kinase	9q22	02514	11491	600085	NP_001128524;NP_001167639;NP_001167638;NP_003168	NM_001135052;NM_001174168;NM_001174167;NM_003177	ENSP00000364904;ENSP00000364898;ENSP00000364899;ENSP00000364907	known	1	0	0	Last Universal Common Ancestor	135	0	Cell cycle,Cell motility and interactions,Cell response to stimuli,Cellular metabolism,Cellular processes,Development,Immune system response,Regulation of intracellular processes and metabolism,Signal transduction	16	chr9	93606181	93657879	CGC,HTMS,WES	lymphoma,myelodysplasia,sarcoma
6854	SYN2	synapsin II	3p25	02857	11495	600755	NP_598328;NP_003169	NM_133625;NM_003178	-	candidate	0	0	0	Eukaryotes	1	0	Cellular processes,Multicellular activities,Signal transduction	83	chr3	12046026	12232122	WES	lymphoma
23345	SYNE1	spectrin repeat containing, nuclear envelope 1	6q25	09762	17089	608441	NP_892006;NP_149062	NM_133650;NM_182961;NM_015293;NM_001134379;NM_001099267;NM_033071	ENSP00000396024;ENSP00000356224	candidate	0	0	0	Eukaryotes	26	11	Cellular processes,Development	47	chr6	152477044	152949466	WES,WGS	head and neck squamous cell carcinoma,chronic lymphocytic leukemia
23224	SYNE2	spectrin repeat containing, nuclear envelope 2	14q23.2	09763	17084	608442	NP_878914;NP_878918;NP_055995;NP_878917	NM_182910;NM_182914;NM_182912;NM_015180;NM_182913	ENSP00000341781;ENSP00000396794;ENSP00000391937;ENSP00000350719	candidate	0	0	0	Eukaryotes	7	11	-1	89	chr14	64375867	64692241	WES,WGS	kidney,glioblastoma
9145	SYNGR1	synaptogyrin 1	22q13.1	06800	11498	603925	NP_663791;NP_663783;NP_004702	NM_145738;NM_145731;NM_004711	ENSP00000332287;ENSP00000318845;ENSP00000370946	candidate	0	0	0	Eukaryotes	2	2	-1	77	chr22	39746016	39777916	WGS	glioblastoma
8867	SYNJ1	synaptojanin 1	21q22.2	09182	11503	604297	NP_001153774;NP_982271;NP_003886;NP_001153778	NM_001160302;NM_203446;NM_003895;NM_001160306	ENSP00000349903;ENSP00000371931;ENSP00000371939	candidate	0	0	0	Eukaryotes	35	5	Cellular metabolism,Cellular processes	70	chr21	34003308	34100351	WGS	lymphoma
171024	SYNPO2	synaptopodin 2	4q26	15456	17732	-	NP_597734;NP_001122406;NP_001122405	NM_133477;NM_001128934;NM_001128933	ENSP00000306015	candidate	0	0	0	Eukaryotes	8	1	-1	-1	chr4	119810192	119979086	WGS	chronic lymphocytic leukemia
401135	SYT14L	synaptotagmin XIV-like	4q13.2	18501	33429	610892	-	NR_027094;NM_001014372	-	candidate	0	0	-1	Eukaryotes	0	0	-1	-1	-	0	0	WES	colorectal
6860	SYT4	synaptotagmin IV	18q12.3	02519	11512	600103	NP_065834	NM_020783	ENSP00000255224	candidate	0	0	0	Eukaryotes	10	2	Cellular processes,Multicellular activities,Signal transduction	-1	chr18	40850309	40854360	WES,WGS	melanoma,chronic lymphocytic leukemia
23334	SZT2	seizure threshold 2 homolog (mouse)	1p34.2	11085	29040	-	NP_056099	NM_001012960;NM_182518;NM_015284;NM_001012961	ENSP00000457168	candidate	0	0	0	-	2	0	-1	88	chr1	43868848	43916148	WES,WGS	breast
134860	TAAR9	trace amine associated receptor 9 (gene/pseudogene)	6q23.2	16308	20977	608282	NP_778227	NM_175057	ENSP00000424607	candidate	0	0	2	-	0	0	Signal transduction	-1	chr6	132859429	132860472	WGS	glioblastoma
10579	TACC2	transforming, acidic coiled-coil containing protein 2	10q26	05600	11523	605302	NP_996744;NP_996742;NP_996743;NP_008928	NM_206862;NM_206860;NM_206861;NM_006997	ENSP00000260733;ENSP00000353763;ENSP00000425062;ENSP00000358001	candidate	0	0	0	Last Universal Common Ancestor	14	1	-1	78	chr10	123809950	124013568	WES	breast
6871	TADA2A	transcriptional adaptor 2A	17q12-q21	03784	11531	602276	NP_001479;NP_597683;NP_001159577	NM_001488;NM_133439;NM_001166105	ENSP00000225396;ENSP00000406699	candidate	0	0	0	Eukaryotes	117	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	35	chr17	35783611	35837084	WGS	breast
6872	TAF1	TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa	Xq13.1	02436	11535	313650	NP_620278;NP_004597	NM_138923;NM_004606	ENSP00000406549;ENSP00000362895	candidate	0	0	1	Eukaryotes	80	5	Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	61	chrX	70586165	70683893	WES	breast
8148	TAF15	TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa	17q11.1-q11.2	09031	11547	601574	NP_003478;NP_631961	NM_003487;NM_139215	ENSP00000309558;ENSP00000466950	known	1	0	0	Eukaryotes	53	7	-1	83	chr17	34144719	34172043	CGC	leukemia,sarcoma
6873	TAF2	TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa	8q24.12	07060	11536	604912	NP_003175	NM_003184	ENSP00000367406	candidate	0	0	0	Last Universal Common Ancestor	23	2	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	69	chr8	120744167	120844804	WES	colorectal
6875	TAF4B	TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa	18q11.2	-	11538	601689	NP_005631;XP_003403744	NM_005640;XM_003403696	ENSP00000269142	candidate	0	0	0	Last Universal Common Ancestor	3	2	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	54	chr18	23806898	23969973	WGS	lung
6886	TAL1	T-cell acute lymphocytic leukemia 1	1p32	01753	11556	187040	NP_003180	NM_003189	ENSP00000294339	known	1	0	0	Metazoans	70	0	Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription	83	chr1	47685395	47691560	CGC	leukemia
6887	TAL2	T-cell acute lymphocytic leukemia 2	9q32	01735	11557	186855	NP_005412	NM_005421	ENSP00000334547	known	1	0	0	Vertebrates	0	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	-1	chr9	108424778	108425101	CGC	leukemia
338398	TAS2R60	taste receptor, type 2, member 60	7q35	18159	20639	613968	NP_803186	NM_177437	ENSP00000327724	candidate	0	0	0	Mammals	0	0	Cell response to stimuli,Signal transduction	-1	chr7	143140546	143141499	WES	melanoma
55773	TBC1D23	TBC1 domain family, member 23	3q12.2	07727	25622	-	NP_001186127;NP_060779	NM_001199198;NM_018309	ENSP00000377700;ENSP00000340693	candidate	0	0	0	Eukaryotes	4	0	Regulation of intracellular processes and metabolism,Signal transduction	-1	chr3	99979863	100042509	WGS	liver
23329	TBC1D30	TBC1 domain family, member 30	12q14.3	-	29164	-	NP_056094	NM_015279	ENSP00000440640	candidate	0	0	0	Eukaryotes	0	1	Regulation of intracellular processes and metabolism,Signal transduction	32	chr12	65218660	65269565	WGS	melanoma
79718	TBL1XR1	transducin (beta)-like 1 X-linked receptor 1	3q26.32	15476	29529	608628	NP_078941	NM_024665	-	candidate	0	0	2	Last Universal Common Ancestor	32	3	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	69	chr3	176744158	176782765	WES	breast,lymphoma
9096	TBX18	T-box 18	6q14-q15	-	11595	604613	NP_001073977	NM_001080508	ENSP00000358677	candidate	0	0	0	Metazoans	0	0	Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Other,Regulation of intracellular processes and metabolism,Regulation of transcription	-1	chr6	85446406	85473899	WES,WGS	pancreas,lung
50945	TBX22	T-box 22	Xq21.1	02253	11600	300307	NP_001103349;NP_058650;NP_001103348	NM_001109879;NM_016954;NM_001109878	ENSP00000362393;ENSP00000396394;ENSP00000362390	candidate	0	0	0	Metazoans	2	4	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	-1	chrX	79277769	79286607	HTMS,WES	breast,lung,ovarian,pancreas,prostate,colorectal
6926	TBX3	T-box 3	12q24.1	03373	11602	601621	NP_005987;NP_057653	NM_005996;NM_016569	ENSP00000257567;ENSP00000257566	candidate	0	0	0	Eukaryotes	7	3	Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Multicellular activities,Other,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	23	chr12	115109649	115121005	WES	breast
6917	TCEA1	transcription elongation factor A (SII), 1	8q11.2	03252	11612	601425	NP_006747;NP_958845	NM_006756;NM_201437	ENSP00000428426;ENSP00000395483	known	1	0	2	Last Universal Common Ancestor	9	1	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	106	chr8	54882952	54934685	CGC	salivary
10915	TCERG1	transcription elongation regulator 1	5q31	10393	15630	605409	NP_006697;NP_001035095	NM_006706;NM_001040006	ENSP00000377943;ENSP00000296702	candidate	0	0	0	Eukaryotes	34	1	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	87	chr5	145826913	145890202	WES	colorectal (hypermutated)
256536	TCERG1L	transcription elongation regulator 1-like	10q26.3	18170	23533	-	NP_777597	NM_174937	ENSP00000357631	candidate	0	0	0	Eukaryotes	5	0	-1	-1	chr10	132891428	133109898	WES	colorectal
6938	TCF12	transcription factor 12	15q21	02725	11623	600480	NP_003196;NP_996921;NP_996919;NP_996923;NP_996920	NM_003205;NM_207038;NM_207036;NM_207040;NM_207037	ENSP00000388940;ENSP00000331057;ENSP00000453737;ENSP00000342459	known	1	0	0	Metazoans	37	3	Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription	100	chr15	57212112	57574782	CGC	sarcoma
6929	TCF3	transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)	19p13.3	00918	11633	147141	NP_003191;NP_001129611	NM_003200;NM_001136139	ENSP00000344375;ENSP00000262965	known	1	0	1	Eukaryotes	154	4	Cellular metabolism,DNA/RNA metabolism and transcription,Development,Immune system response,Regulation of intracellular processes and metabolism,Regulation of transcription	86	chr19	1611709	1650247	CGC	leukemia
6934	TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)	10q25.3	03751	11641	602228	NP_001185456;NP_001139756;NP_001185459;NP_001185454;NP_110383;NP_001185455;NP_001139755;NP_001185460;NP_001185457;NP_001139746;NP_001139757;NP_001139758;NP_001185458	NM_001198527;NM_001146284;NM_001198530;NM_001198525;NM_030756;NM_001198526;NM_001146283;NM_001198531;NM_001198528;NM_001146274;NM_001146285;NM_001146286;NM_001198529	ENSP00000444972;ENSP00000347949;ENSP00000446238;ENSP00000446172;ENSP00000358404	known	1	0	0	Opisthokonts	31	0	Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	100	chr10	114710516	114925728	CGC,WES	colorectal,colorectal (hypermutated),colorectal (non-hypermutated)
8115	TCL1A	T-cell leukemia/lymphoma 1A	14q32.1	01744	11648	186960	NP_068801;NP_001092195	NM_021966;NM_001098725	ENSP00000451506;ENSP00000385036	known	1	0	0	Mammals	7	4	-1	65	chr14	96178095	96180403	CGC	leukemia
27004	TCL6	T-cell leukemia/lymphoma 6 (non-protein coding)	14q32.1	05104	13463	604412	-	NM_012468;NM_020554;NM_020552;NM_020550;NM_014418;NM_020553;NR_028288	-	known	1	0	-1	Primates	0	0	-1	24	-	0	0	CGC	leukemia
343521	TCTEX1D4	Tctex1 domain containing 4	1p34.1	15762	32315	611713	NP_001013654	NM_001013632	ENSP00000361274	candidate	0	0	0	Eukaryotes	5	0	-1	-1	chr1	45271678	45272340	WGS	lymphoma
6996	TDG	thymine-DNA glycosylase	12q24.1	03251	11700	601423	NP_003202	NM_001008411;NM_003211	ENSP00000376611	candidate	0	0	1	Last Universal Common Ancestor	39	3	Cellular metabolism,DNA/RNA metabolism and transcription	71	chr12	104370694	104380865	HTMS	breast,lung,ovarian,pancreas,prostate
221400	TDRD6	tudor domain containing 6	6p12.3	18172	21339	611200	NP_001010870;NP_001161831	NM_001010870;NM_001168359	ENSP00000443299	candidate	0	0	0	Eukaryotes	2	0	-1	-1	chr6	46655866	46665824	WES	breast
7007	TECTA	tectorin alpha	11q22-q24	03985	11720	602574	NP_005413	NM_005422	ENSP00000264037	candidate	0	0	0	Eukaryotes	0	0	Cell motility and interactions,Cell response to stimuli	16	chr11	120973375	121061512	WES	breast
7015	TERT	telomerase reverse transcriptase	5p15.33	01754	11730	187270	NP_937983;NP_001180305	NM_198254;NM_198255;NM_198253;NM_001193376	ENSP00000334346;ENSP00000309572	candidate	0	0	0	Eukaryotes	41	5	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism	14	chr5	1253846	1295104	WES	lung
80312	TET1	tet methylcytosine dioxygenase 1	10q21	09694	29484	607790	NP_085128	NM_030625	ENSP00000362748	known	1	0	0	Metazoans	1	4	-1	-1	chr10	70332096	70451568	CGC	leukemia
54790	TET2	tet methylcytosine dioxygenase 2	4q24	07876	25941	612839	NP_001120680;NP_060098	NM_001127208;NM_017628	ENSP00000369351;ENSP00000306705	known	0	1	0	Metazoans	4	1	-1	-1	chr4	106155100	106197673	CGC,WES	myelodysplasia
56159	TEX11	testis expressed 11	Xq13.1	02256	11733	300311	NP_001003811;NP_112566	NM_001003811;NM_031276	ENSP00000379226;ENSP00000363453	candidate	0	0	0	Eukaryotes	44	0	-1	5	chrX	69748948	70099960	WGS	prostate
83741	TFAP2D	transcription factor AP-2 delta (activating enhancer binding protein 2 delta)	6p12.1	11627	15581	610161	NP_758438	NM_172238	ENSP00000008391	candidate	0	0	0	Metazoans	0	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	-1	chr6	50682829	50740574	WES	lung
339488	TFAP2E	transcription factor AP-2 epsilon (activating enhancer binding protein 2 epsilon)	1p34.3	18174	30774	614428	NP_848643	NM_178548	ENSP00000362332	candidate	0	0	0	Metazoans	0	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	-1	chr1	36039528	36060274	WGS	lymphoma
7030	TFE3	transcription factor binding to IGHM enhancer 3	Xp11.22	02439	11752	314310	NP_006512	NM_006521	ENSP00000314129	known	1	0	0	Opisthokonts	56	1	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	80	chrX	48887672	48900752	CGC	kidney,sarcoma
7942	TFEB	transcription factor EB	6p21	02847	11753	600744	NP_001161299;NP_009093	NM_001167827;NM_007162	ENSP00000384203;ENSP00000230323	known	1	0	0	Opisthokonts	3	4	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	52	chr6	41652340	41658951	CGC	kidney
10342	TFG	TRK-fused gene	3q12.2	03932	11758	602498	NP_006061;NP_001007566;NP_001182408;NP_001182407	NM_006070;NM_001007565;NM_001195479;NM_001195478	ENSP00000419960;ENSP00000417952;ENSP00000240851	known	1	0	1	Eukaryotes	21	1	Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction	104	chr3	100432530	100467372	CGC	lung,lymphoma,thyroid
29844	TFPT	TCF3 (E2A) fusion partner (in childhood Leukemia)	19q13	10266	13630	609519	NP_037474	NM_013342	ENSP00000375639	known	1	0	0	Metazoans	35	1	-1	44	chr19	54610360	54618079	CGC	leukemia
7037	TFRC	transferrin receptor (p90, CD71)	3q29	01812	11763	190010	NP_003225;NP_001121620	NM_003234;NM_001128148	ENSP00000353224;ENSP00000376197	known	1	0	0	Last Universal Common Ancestor	43	4	Cellular processes,Regulation of intracellular processes and metabolism	105	chr3	195778816	195802231	CGC	non-hodgkin lymphoma
7038	TG	thyroglobulin	8q24	01782	11764	188450	NP_003226	NM_003235	ENSP00000220616	candidate	0	0	0	Last Universal Common Ancestor	9	2	Cellular metabolism,Signal transduction	57	chr8	133879246	134147035	WES	breast
7045	TGFBI	transforming growth factor, beta-induced, 68kDa	5q31	03409	11771	601692	NP_000349	NM_000358	ENSP00000416330	candidate	0	0	0	Last Universal Common Ancestor	9	8	Cell motility and interactions,Cell response to stimuli,Regulation of intracellular processes and metabolism	87	chr5	135364745	135397268	WGS	breast
7048	TGFBR2	transforming growth factor, beta receptor II (70/80kDa)	3p22	01823	11773	190182	NP_003233;NP_001020018	NM_003242;NM_001024847	ENSP00000351905;ENSP00000295754	candidate	0	0	0	Last Universal Common Ancestor	13	15	Cell cycle,Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction	106	chr3	30648376	30733088	WES	colorectal,colorectal (hypermutated),pancreas
7053	TGM3	transglutaminase 3 (E polypeptide, protein-glutamine-gamma-glutamyltransferase)	20q11.2	02584	11779	600238	NP_003236	NM_003245	ENSP00000370867	candidate	0	0	0	Metazoans	14	0	Cellular metabolism,Cellular processes,Development,Multicellular activities	46	chr20	2290302	2321224	WES	colorectal
7059	THBS3	thrombospondin 3	1q21	01767	11787	188062	NP_001239536;NP_001239537;NP_009043	NR_045553;NM_001252607;NM_001252608;NM_007112	ENSP00000392207;ENSP00000357362	candidate	0	0	0	Last Universal Common Ancestor	1	1	Cell motility and interactions	47	chr1	155165635	155177667	WES	breast
8563	THOC5	THO complex 5	22q12.2	16650	19074	612733	NP_001002878;NP_001002879;NP_003669;NP_001002877	NM_001002878;NM_001002879;NM_003678;NM_001002877	ENSP00000380971;ENSP00000380970;ENSP00000380969	candidate	0	0	0	Eukaryotes	7	1	-1	60	chr22	29904449	29945136	WES	breast
9967	THRAP3	thyroid hormone receptor associated protein 3	1p34.3	07543	22964	603809	NP_005110	NM_005119	ENSP00000346634	known	1	0	1	Eukaryotes	63	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	5	chr1	36748165	36769615	CGC	bone cyst
7069	THRSP	thyroid hormone responsive	11q14.1	03566	11800	601926	NP_003242	NM_003251	ENSP00000281030	candidate	0	0	0	Vertebrates	0	0	-1	-1	chr11	77774928	77775365	WGS	breast
221981	THSD7A	thrombospondin, type I, domain containing 7A	7p21.3	-	22207	612249	NP_056019	NM_015204	-	candidate	0	0	0	Last Universal Common Ancestor	4	0	-1	52	chr7	11415424	11871572	WES	head and neck squamous cell carcinoma
80731	THSD7B	thrombospondin, type I, domain containing 7B	2q22.1	-	29348	-	NP_001073896	NM_001080427	ENSP00000413841	candidate	0	0	0	Last Universal Common Ancestor	1	0	-1	-1	chr2	137748462	138434172	WES	prostate
7074	TIAM1	T-cell lymphoma invasion and metastasis 1	21q22.1|21q22.11	02820	11805	600687	NP_003244	NM_003253	ENSP00000286827	candidate	0	0	0	Eukaryotes	33	3	Signal transduction	89	chr21	32492689	32639288	WES	colorectal
8914	TIMELESS	timeless homolog (Drosophila)	12q12-q13	04864	11813	603887	NP_003911	NM_003920	ENSP00000450607	candidate	0	0	0	Eukaryotes	20	0	Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription	77	chr12	56811503	56827954	WES	breast
84076	TKTL2	transketolase-like 2	4q32.2	13159	25313	-	NP_115512	NM_032136	ENSP00000280605	candidate	0	0	0	Last Universal Common Ancestor	2	1	-1	-1	chr4	164393009	164394886	WES	lung
7091	TLE4	transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)	9q21.31	-	11840	605132	NP_008936	NM_007005	ENSP00000365703	candidate	0	0	1	Last Universal Common Ancestor	11	10	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	84	chr9	82187706	82340056	WES	acute myeloid leukemia
7093	TLL2	tolloid-like 2	10q23-q24	05993	11844	606743	NP_036597	NM_012465	ENSP00000350630	candidate	0	0	1	Last Universal Common Ancestor	0	0	Cellular metabolism	20	chr10	98127848	98273442	WES	lymphoma
7094	TLN1	talin 1	9p13	01726	11845	186745	NP_006280	NM_006289	ENSP00000316029	candidate	0	0	1	Eukaryotes	44	3	Cell motility and interactions,Cellular processes	71	chr9	35697791	35725691	WES	breast
7097	TLR2	toll-like receptor 2	4q32	04323	11848	603028	NP_003255	NM_003264	-	candidate	0	0	0	Eukaryotes	25	5	Cell cycle,Cell response to stimuli,Cellular processes,Development,Immune system response,Regulation of intracellular processes and metabolism,Signal transduction	19	chr4	154624060	154626411	WES	chronic lymphocytic leukemia
7099	TLR4	toll-like receptor 4	9q33.1	04325	11850	603030	NP_612564;NP_003257;NP_612567	NM_138554;NM_003266;NM_138557;NR_024168;NR_024169;NM_138556	ENSP00000363089	candidate	0	0	0	Eukaryotes	48	5	Cell response to stimuli,Cellular metabolism,Development,Immune system response,Regulation of intracellular processes and metabolism,Signal transduction	67	chr9	120466751	120476923	HTMS	breast,lung,ovarian,pancreas,prostate
51311	TLR8	toll-like receptor 8	Xp22	02296	15632	300366	NP_619542	NM_016610;NM_138636	ENSP00000218032	candidate	0	0	0	Last Universal Common Ancestor	4	0	Cell response to stimuli,Cellular metabolism,Immune system response,Regulation of intracellular processes and metabolism,Signal transduction	4	chrX	12937163	12940282	WGS	melanoma
54106	TLR9	toll-like receptor 9	3p21.3	05685	15633	605474	NP_059138	NM_138688;NM_017442	ENSP00000353874	candidate	0	0	0	Last Universal Common Ancestor	27	0	Cell response to stimuli,Cellular metabolism,Immune system response,Regulation of intracellular processes and metabolism,Signal transduction	-1	chr3	52255236	52258328	WES	colorectal
3195	TLX1	T-cell leukemia homeobox 1	10q24	01728	5056	186770	NP_001182446;NP_005512	NM_001195517;NM_005521	ENSP00000434914	known	1	0	0	Eukaryotes	4	2	Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription	1	chr10	102891299	102896667	CGC	leukemia
30012	TLX3	T-cell leukemia homeobox 3	5q35.1	06868	13532	604640	NP_066305	NM_021025	ENSP00000296921	known	1	0	0	Eukaryotes	2	2	Cell cycle,Cell motility and interactions,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription	9	chr5	170736370	170738600	CGC,WGS	leukemia,lymphoma
53346	TM6SF1	transmembrane 6 superfamily member 1	15q24-q26	08411	11860	606562	NP_075379;NP_001138375	NM_023003;NM_001144903	ENSP00000317000	candidate	0	0	0	Eukaryotes	0	1	-1	65	chr15	83776433	83805421	WGS	lymphoma,prostate
81501	TM7SF4	transmembrane 7 superfamily member 4	8q23	07295	18549	605933	NP_110415	NM_030788	ENSP00000297581	candidate	0	0	0	Vertebrates	0	2	Development	40	chr8	105360781	105368423	WES	pancreas
114908	TMEM123	transmembrane protein 123	11q22.1	-	30138	606356	NP_443164	NM_052932	ENSP00000381204	candidate	0	0	0	Vertebrates	4	1	-1	106	chr11	102272272	102323354	WES	breast
114795	TMEM132B	transmembrane protein 132B	12q24.31	17230	29397	-	NP_443139	NM_052907	-	candidate	0	0	0	Eukaryotes	0	3	-1	-1	chr12	125811170	126139253	WES	melanoma
121256	TMEM132D	transmembrane protein 132D	12q24.33	13906	29411	611257	NP_597705	NM_133448	ENSP00000408581	candidate	0	0	0	Eukaryotes	2	0	-1	-1	chr12	129558423	130387884	WES	lung
55754	TMEM30A	transmembrane protein 30A	6q14.1	15535	16667	611028	NP_001137430;NP_060717	NM_001143958;NM_018247	ENSP00000230461	candidate	0	0	0	Eukaryotes	3	6	-1	97	chr6	75965821	75994354	WES	lymphoma,non-hodgkin lymphoma
7113	TMPRSS2	transmembrane protease, serine 2	21q22.3	03637	11876	602060	NP_001128571;NP_005647	NM_001135099;NM_005656	ENSP00000381588;ENSP00000330330	known	1	0	0	Last Universal Common Ancestor	0	0	Cellular metabolism	35	chr21	42839661	42879931	CGC	prostate
164656	TMPRSS6	transmembrane protease, serine 6	22q12.3	10270	16517	609862	NP_705837	NM_153609	ENSP00000334962	candidate	0	0	0	Last Universal Common Ancestor	21	1	Cell motility and interactions,Cellular metabolism,Development,Multicellular activities,Signal transduction	63	chr22	37462123	37499460	WES	breast
7117	TMSL3	thymosin-like 3	4q22.1	10273	11885	-	-	NM_183049	-	candidate	0	0	-1	Metazoans	0	0	Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism	36	-	0	0	WES	lymphoma
160335	TMTC2	transmembrane and tetratricopeptide repeat containing 2	12q21.31	13230	25440	-	NP_689801	NM_152588	ENSP00000322300	candidate	0	0	0	Last Universal Common Ancestor	1	6	-1	-1	chr12	83081366	83526165	WES	chronic lymphocytic leukemia
160418	TMTC3	transmembrane and tetratricopeptide repeat containing 3	12q21.32	10243	26899	-	NP_861448	NM_181783	ENSP00000266712	candidate	0	0	0	Last Universal Common Ancestor	14	13	-1	-1	chr12	88542093	88589423	WES	pancreas
79089	TMUB2	transmembrane and ubiquitin-like domain containing 2	17q21.31	14542	28459	-	NP_803190;NP_001070142;NP_077012	NM_177441;NM_001076674;NM_024107	ENSP00000444565;ENSP00000350672;ENSP00000313214	candidate	0	0	0	Metazoans	1	4	Cellular metabolism,Cellular processes	69	chr17	42266388	42268229	WGS	lung
7124	TNF	tumor necrosis factor	6p21.3	01855	11892	191160	NP_000585	NM_000594	ENSP00000398698	candidate	0	0	0	Vertebrates	68	1	Cell cycle,Cell motility and interactions,Cell response to stimuli,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Immune system response,Multicellular activities,Other,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	39	chr6	31543519	31545311	WES	lymphoma
7128	TNFAIP3	tumor necrosis factor, alpha-induced protein 3	6q23	01857	11896	191163	NP_006281	NM_006290	ENSP00000237289	known	0	1	0	Metazoans	64	3	Cell cycle,Development,Regulation of intracellular processes and metabolism,Signal transduction	104	chr6	138192365	138202453	CGC,WES	lymphoma
8764	TNFRSF14	tumor necrosis factor receptor superfamily, member 14	1p36.32	04122	11912	602746	NP_003811	NM_003820	ENSP00000347948	known	0	1	0	Metazoans	84	0	Cell cycle,Signal transduction	48	chr1	2488104	2494709	CGC,WES	lymphoma,non-hodgkin lymphoma
608	TNFRSF17	tumor necrosis factor receptor superfamily, member 17	16p13.1	00144	11913	109545	NP_001183	NM_001192	ENSP00000053243	known	1	0	0	Mammals	9	1	Signal transduction	3	chr16	12059182	12061701	CGC	lymphoma
943	TNFRSF8	tumor necrosis factor receptor superfamily, member 8	1p36	01074	11923	153243	NP_694421;NP_001234	NM_152942;NM_001243	ENSP00000263932;ENSP00000398337	candidate	0	0	0	Vertebrates	12	0	Cell cycle,Cellular metabolism,Development,Regulation of intracellular processes and metabolism,Signal transduction	65	chr1	12123656	12202585	WGS	melanoma
8743	TNFSF10	tumor necrosis factor (ligand) superfamily, member 10	3q26	04670	11925	603598	NP_001177871;NP_003801;NP_001177872	NM_001190942;NR_033994;NM_003810;NM_001190943	ENSP00000389931;ENSP00000241261	candidate	0	0	0	Metazoans	23	3	Cell cycle,Development,Regulation of intracellular processes and metabolism,Signal transduction	79	chr3	172224285	172241174	WES	melanoma
944	TNFSF8	tumor necrosis factor (ligand) superfamily, member 8	9q33	04852	11938	603875	NP_001239219;NP_001235	NM_001252290;NM_001244	-	candidate	0	0	0	Vertebrates	2	0	Cell cycle,Development,Regulation of intracellular processes and metabolism,Signal transduction	49	chr9	117666214	117692583	WES	melanoma
63923	TNN	tenascin N	1q23-q24	-	22942	-	NP_071376	NM_022093	ENSP00000239462	candidate	0	0	0	Last Universal Common Ancestor	3	0	Cell cycle,Cell motility and interactions,Development,Signal transduction	38	chr1	175046555	175116204	WES	colorectal,lung
3842	TNPO1	transportin 1	5q13.2	04210	6401	602901	NP_694858;NP_002261	NM_153188;NM_002270	ENSP00000398524	candidate	0	0	3	Eukaryotes	41	9	Cellular processes	109	chr5	72144212	72201234	WGS	melanoma
7143	TNR	tenascin R (restrictin, janusin)	1q24	03589	11953	601995	NP_003276	NM_003285	ENSP00000356646	candidate	0	0	0	Eukaryotes	9	0	Cell cycle,Cell motility and interactions,Development,Signal transduction	44	chr1	175292496	175375850	WES,WGS	pancreas,prostate
7150	TOP1	topoisomerase (DNA) I	20q12-q13.1	00535	11986	126420	NP_003277	NM_003286	ENSP00000354522	known	1	0	0	Last Universal Common Ancestor	158	5	Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription	104	chr20	39690033	39751934	CGC	leukemia
7157	TP53	tumor protein p53	17p13.1	01859	11998	191170	NP_001119587;NP_001119586;NP_001119584;NP_001119589;NP_001119588;NP_000537;NP_001119585;NP_001119590	NM_001126115;NM_001126114;NM_001126112;NM_001126117;NM_001126116;NM_000546;NM_001126113;NM_001126118	ENSP00000269305;ENSP00000391478;ENSP00000398846;ENSP00000391127	known	0	1	0	Eukaryotes	741	16	Cell cycle,Cell response to stimuli,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	70	chr17	7572930	7579912	CGC,HTMS,WES,WGS	adrenocortical,breast,colorectal,glioma,lung,other,sarcoma,glioblastoma,ovarian,pancreas,prostate,bladder,cholangiocarcinoma,chronic lymphocytic leukemia,colorectal (non-hypermutated),endometrium,gastric,head and neck squamous cell carcinoma,kidney,liver,lymphoma,medulloblastoma,myelodysplasia,myeloma,non-hodgkin lymphoma
94241	TP53INP1	tumor protein p53 inducible nuclear protein 1	8q22	09367	18022	606185	NP_150601;NP_001129205	NM_033285;NM_001135733	ENSP00000390063;ENSP00000344215	candidate	0	0	0	Metazoans	3	9	Cell cycle	-1	chr8	95942710	95953169	WES	acute myeloid leukemia
8626	TP63	tumor protein p63	3q28	04469	15979	603273	NP_003713;NP_001108451;NP_001108454;NP_001108453;NP_001108450;NP_001108452	NM_003722;NM_001114979;NM_001114982;NM_001114981;NM_001114978;NM_001114980	ENSP00000407144;ENSP00000346614;ENSP00000392488;ENSP00000264731	candidate	0	0	0	Eukaryotes	77	8	Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	90	chr3	189349305	189612288	WES,WGS	head and neck squamous cell carcinoma,melanoma
7170	TPM3	tropomyosin 3	1q21.2	01840	12012	191030	NP_705935;NP_689476;NP_001036816;NP_001036817;NP_001036818	NM_153649;NM_152263;NM_001043351;NM_001043352;NM_001043353	ENSP00000357521	known	1	0	2	Metazoans	47	6	Multicellular activities	42	chr1	154141783	154164494	CGC	lung,lymphoma,thyroid
7171	TPM4	tropomyosin 4	19p13.1	11734	12013	600317	NP_003281;NP_001138632	NM_003290;NM_001145160	ENSP00000300933	known	1	0	5	Metazoans	4	4	-1	87	chr19	16178435	16212153	CGC	lymphoma
7173	TPO	thyroid peroxidase	2p25	06000	12015	606765	NP_783653;NP_783652;NP_001193674;NP_001193673;NP_000538;NP_783650	NM_175720;NM_175722;NM_175721;NM_001206745;NM_001206744;NM_000547;NM_175719	ENSP00000318820;ENSP00000329869;ENSP00000371636;ENSP00000263886;ENSP00000371633	candidate	0	0	0	Last Universal Common Ancestor	2	2	Cell response to stimuli,Cellular metabolism	9	chr2	1418181	1546243	WES	pancreas
7175	TPR	translocated promoter region (to activated MET oncogene)	1q25	08927	12017	189940	NP_003283	NM_003292	-	known	1	0	0	Last Universal Common Ancestor	66	1	Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of transcription	107	chr1	186283106	186344160	CGC	thyroid
284355	TPRX1	tetra-peptide repeat homeobox 1	19q13.33	13447	32174	611166	NP_940881	NM_198479	ENSP00000323455	candidate	0	0	0	Primates	0	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	-1	chr19	48305035	48306240	WGS	lymphoma
6955	TRA@	T cell receptor alpha locus	14q11.2	-	12027	186880	-	-	-	known	1	0	-1	Vertebrates	30	0	Cell response to stimuli	97	-	0	0	CGC,WGS	leukemia,glioblastoma
80305	TRABD	TraB domain containing	22q13.33	11450	28805	-	NP_079480	NM_025204	ENSP00000305664	candidate	0	0	0	Last Universal Common Ancestor	3	1	-1	1	chr22	50632005	50636945	WGS	lymphoma
7187	TRAF3	TNF receptor-associated factor 3	14q32.32	03539	12033	601896	NP_001186356;NP_663777;NP_663778;NP_003291	NM_001199427;NM_145725;NM_145726;NM_003300	ENSP00000454207	candidate	0	0	0	Eukaryotes	102	1	Cell cycle,Development,Regulation of intracellular processes and metabolism,Signal transduction	69	chr14	103336539	103372118	WES	lymphoma
7188	TRAF5	TNF receptor-associated factor 5	1q32	03834	12035	602356	NP_001029082;NP_004610;NP_665702	NM_001033910;NM_004619;NM_145759	ENSP00000261464;ENSP00000336825	candidate	0	0	0	Eukaryotes	63	0	Cell cycle,Regulation of intracellular processes and metabolism,Signal transduction	52	chr1	211526582	211546041	HTMS	breast,lung,ovarian,pancreas,prostate
7109	TRAPPC10	trafficking protein particle complex 10	21q22.3	03656	11868	602103	NP_003265	NM_001001723;NM_003274	ENSP00000291574	candidate	0	0	0	Eukaryotes	14	1	Cellular processes	69	chr21	45432375	45523409	WGS	melanoma
6957	TRB@	T cell receptor beta locus	7q34	-	12155	186930	-	-	-	known	1	0	-1	-	0	0	-1	-1	-	0	0	CGC,WGS	leukemia,melanoma
6964	TRD@	T cell receptor delta locus	14q11.2	-	12252	186810	-	-	-	known	1	0	-1	-	4	0	-1	20	-	0	0	CGC	leukemia
10221	TRIB1	tribbles homolog 1 (Drosophila)	8q24.13	09863	16891	609461	NP_079471	NM_025195	ENSP00000312150	known	0	0	0	Last Universal Common Ancestor	23	5	Cell cycle,Cell motility and interactions,Cell response to stimuli,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	90	chr8	126443145	126448710	CGC,Amplified	
81559	TRIM11	tripartite motif containing 11	1q42.13	07429	16281	607868	NP_660215	NM_145214	ENSP00000284551	candidate	0	0	0	Eukaryotes	18	0	-1	-1	chr1	228582409	228594262	HTMS	breast,lung,ovarian,pancreas,prostate
8805	TRIM24	tripartite motif containing 24	7q32-q34	04556	11812	603406	NP_003843;NP_056989	NM_003852;NM_015905	ENSP00000390829	known	1	0	0	Eukaryotes	75	4	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	83	chr7	138145294	138269693	CGC	leukemia
5987	TRIM27	tripartite motif containing 27	6p22	15996	9975	602165	NP_006501	NM_030950;NM_006510	ENSP00000366404	known	1	0	0	Eukaryotes	116	0	Cellular metabolism,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription	106	chr6	28871850	28891409	CGC	thyroid
51592	TRIM33	tripartite motif containing 33	1p13.1	10423	16290	605769	NP_148980;NP_056990	NM_033020;NM_015906	ENSP00000351250	known	1	0	0	Eukaryotes	65	3	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	82	chr1	114940273	115053697	CGC	thyroid
4591	TRIM37	tripartite motif containing 37	17q23.2	05463	7523	605073	NP_001005207;NP_056109	NM_001005207;NM_015294	ENSP00000376785;ENSP00000262294	candidate	0	0	0	Eukaryotes	60	3	-1	75	chr17	57076741	57181755	HTMS	breast,lung,ovarian,pancreas,prostate
84675	TRIM55	tripartite motif containing 55	8q13.1	05927	14215	606469	NP_149047;NP_908975;NP_908973;NP_908974	NM_033058;NM_184087;NM_184085;NM_184086	ENSP00000323913;ENSP00000297348	candidate	0	0	0	Eukaryotes	70	0	Signal transduction	-1	chr8	67039504	67086825	WGS	prostate
11078	TRIOBP	TRIO and F-actin binding protein	22q13.1	11028	17009	609761	NP_619538;NP_008963;NP_001034230	NM_138632;NM_007032;NM_001039141	ENSP00000384312;ENSP00000383913	candidate	0	0	0	Last Universal Common Ancestor	9	1	Cell response to stimuli,Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism	106	chr22	38097373	38168766	WES	breast
9321	TRIP11	thyroid hormone receptor interactor 11	14q31-q32	05143	12305	604505	NP_004230	NM_004239	ENSP00000267622	known	1	0	0	Last Universal Common Ancestor	15	3	Cellular metabolism,DNA/RNA metabolism and transcription	61	chr14	92436020	92506029	CGC	leukemia
7216	TRO	trophinin	Xp11.22-p11.21	02134	12326	300132	NP_001034794;NP_808224;NP_057241	NM_001039705;NM_177556;NM_177555;NM_016157;NM_177558;NM_177557	ENSP00000173898;ENSP00000405126;ENSP00000364181;ENSP00000318278;ENSP00000364162;ENSP00000382641	candidate	0	0	0	Last Universal Common Ancestor	14	0	Cell motility and interactions,Development	51	chrX	54948680	54957450	WES	chronic lymphocytic leukemia
4308	TRPM1	transient receptor potential cation channel, subfamily M, member 1	15q13.3	04656	7146	603576	NP_002411;NP_001238959;NP_001238953;NP_001238949	NM_002420;NM_001252030;NM_001252024;NM_001252020	ENSP00000437849;ENSP00000256552;ENSP00000453851;ENSP00000380897	candidate	0	0	0	Eukaryotes	1	1	Cellular processes	19	chr15	31294028	31453162	WGS	glioblastoma
140803	TRPM6	transient receptor potential cation channel, subfamily M, member 6	9q21.13	06112	17995	607009	NP_001170781;NP_060132;NP_001170782	NM_001177310;NM_017662;NM_001177311	ENSP00000396672;ENSP00000354962;ENSP00000354006	candidate	0	0	0	Eukaryotes	4	2	Cellular metabolism,Cellular processes	16	chr9	77339532	77473664	WGS	chronic lymphocytic leukemia
59341	TRPV4	transient receptor potential cation channel, subfamily V, member 4	12q24.1	05667	18083	605427	NP_671737;NP_001170899;NP_001170904;NP_067638;NP_001170902	NM_147204;NM_001177428;NM_001177433;NM_021625;NM_001177431	ENSP00000442167;ENSP00000444336;ENSP00000443611;ENSP00000261740;ENSP00000442738	candidate	0	0	0	Eukaryotes	21	1	Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction	29	chr12	110221429	110252601	WGS	chronic lymphocytic leukemia
56302	TRPV5	transient receptor potential cation channel, subfamily V, member 5	7q35	05981	3145	606679	NP_062815	NM_019841	ENSP00000265310	candidate	0	0	1	Eukaryotes	10	0	Cellular metabolism,Cellular processes	33	chr7	142605683	142630556	WES	glioblastoma
8295	TRRAP	transformation/transcription domain-associated protein	7q21.2-q22.1	04310	12347	603015	NP_003487;NP_001231509	NM_003496;NM_001244580	ENSP00000352925;ENSP00000347733	candidate	0	0	0	Eukaryotes	77	5	Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	90	chr7	98478774	98609975	WGS	liver
7248	TSC1	tuberous sclerosis 1	9q34	05594	12362	605284	NP_001155898;NP_000359;NP_001155899	NM_001162426;NM_000368;NM_001008567;NM_001162427	ENSP00000298552;ENSP00000444017	known	0	1	0	Opisthokonts	57	2	Cell cycle,Cell motility and interactions,Cell response to stimuli,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	98	chr9	135771625	135804259	CGC,WES,WGS	kidney,liver
7249	TSC2	tuberous sclerosis 2	16p13.3	01850	12363	191092	NP_001070651;NP_001107854;NP_000539	NM_001077183;NM_001114382;NM_021055;NM_021056;NM_000548	ENSP00000219476;ENSP00000384468;ENSP00000344383	known	0	1	0	Eukaryotes	62	0	Cell cycle,Cell motility and interactions,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction	67	chr16	2098617	2138608	CGC,WES	pancreas
8848	TSC22D1	TSC22 domain family, member 1	13q14	07414	16826	607715	NP_006013;NP_001230726;NP_904358;NP_001230727;NP_001230728	NM_006022;NM_001243797;NM_183422;NM_001243798;NM_001243799	-	candidate	0	0	0	Metazoans	190	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	101	chr13	45008765	45150210	WES	lymphoma
7253	TSHR	thyroid stimulating hormone receptor	14q31	04537	12373	603372	NP_001018046;NP_000360;NP_001136098	NM_001018036;NM_000369;NM_001142626	ENSP00000298171;ENSP00000340113;ENSP00000450549	known	1	0	0	Metazoans	24	5	Cell cycle,Regulation of intracellular processes and metabolism,Signal transduction	10	chr14	81422025	81610694	CGC	thyroid
128553	TSHZ2	teashirt zinc finger homeobox 2	20q13.2	10730	13010	614118	NP_775756;NP_001180350	NM_173485;NM_001193421	-	candidate	0	0	0	Eukaryotes	3	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	46	chr20	51589833	51873099	WGS	chronic lymphocytic leukemia
54084	TSPEAR	thrombospondin-type laminin G domain and EAR repeats	21q22.3	09845	1268	612920	NP_659428	NM_144991	ENSP00000321987	candidate	0	0	0	Eukaryotes	6	0	-1	-1	chr21	45919669	46131429	WES	glioblastoma
84630	TTBK1	tau tubulin kinase 1	6p21.1	11653	19140	-	NP_115927	NM_032538	ENSP00000259750	candidate	0	0	0	Last Universal Common Ancestor	8	0	Cellular metabolism,Cellular processes	-1	chr6	43214399	43253111	WGS	melanoma
146057	TTBK2	tau tubulin kinase 2	15q15.2	10288	19141	611695	NP_775771	NM_173500	-	candidate	0	0	0	Last Universal Common Ancestor	17	0	Cellular metabolism,Cellular processes	45	chr15	43037996	43170815	WGS	lung
118491	TTC18	tetratricopeptide repeat domain 18	10q22.2	15583	30726	-	NP_660153	NM_145170	ENSP00000310829	candidate	0	0	0	Eukaryotes	0	1	-1	-1	chr10	75013736	75114554	WES	lymphoma
54777	TTC40	tetratricopeptide repeat domain 40	10q26.3	12596	25247	-	NP_001186978;XP_003119525;NP_775843;XP_003118674	NM_001200049;XM_003119477;NM_017609;NM_173572;XM_003118626	ENSP00000357575	candidate	0	0	0	-	0	0	-1	29	chr10	134621928	134755988	WGS	glioblastoma
7272	TTK	TTK protein kinase	6q13-q21	04973	12401	604092	NP_001160163;NP_003309	NM_001166691;NM_003318	ENSP00000230510;ENSP00000358813	candidate	0	0	0	Last Universal Common Ancestor	23	4	Cell cycle,Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism	24	chr6	80715561	80751916	WES	gastric
150465	TTL	tubulin tyrosine ligase	2q13	12206	21586	608291	NP_714923	NM_153712	ENSP00000233336	known	1	0	0	Eukaryotes	1	0	Cell cycle,Cellular metabolism,Cellular processes,Development,Regulation of intracellular processes and metabolism	-1	chr2	113239922	113286369	CGC	leukemia
284076	TTLL6	tubulin tyrosine ligase-like family, member 6	17q21.32	08763	26664	610849	NP_775894;NP_001124390	NM_173623;NM_001130918	ENSP00000377043;ENSP00000399211	candidate	0	0	0	Eukaryotes	1	0	Cellular metabolism,Cellular processes	-1	chr17	46846354	46894434	WGS	melanoma
7273	TTN	titin	2q31	01787	12403	188840	NP_597681;NP_596870;NP_596869;NP_597676;NP_003310	NM_133437;NM_133379;NM_133378;NM_133432;NM_003319	ENSP00000465570;ENSP00000467141;ENSP00000434586;ENSP00000343764;ENSP00000354117;ENSP00000352154;ENSP00000340554	candidate	0	0	0	Last Universal Common Ancestor	118	0	Cell cycle,Cellular metabolism,Cellular processes,Development,Multicellular activities,Signal transduction	62	chr2	179576672	179669369	WES,WGS	colorectal (non-hypermutated),gastric,lung
7278	TUBA3C	tubulin, alpha 3c	13q11	03958	12408	602528	NP_005992	NM_006001;NM_079836	-	candidate	0	0	16	Eukaryotes	22	0	Cellular metabolism,Cellular processes	34	chr13	19748006	19753703	WES	lung
51807	TUBA8	tubulin, alpha 8	22q11.1	05763	12410	605742	NP_001180343;NP_061816	NM_001193414;NM_018943	ENSP00000333326	candidate	0	0	14	Eukaryotes	11	2	Cellular metabolism,Cellular processes	16	chr22	18604246	18613900	WGS	lymphoma
79861	TUBAL3	tubulin, alpha-like 3	10p15.1	08640	23534	-	NP_001165335;NP_079079	NM_001171864;NM_024803	ENSP00000418799;ENSP00000369784	candidate	0	0	9	Eukaryotes	16	2	Cellular metabolism,Cellular processes	25	chr10	5435483	5443050	WGS	prostate
203068	TUBB	tubulin, beta class I	6p21.33	-	20778	191130	NP_821133	NM_178014	ENSP00000339001	candidate	0	0	23	Eukaryotes	188	2	Cell cycle,Cellular metabolism,Cellular processes,Development,Immune system response,Regulation of intracellular processes and metabolism	109	chr6	30688284	30692171	WGS	lymphoma
219743	TYSND1	trypsin domain containing 1	10q22.1	15593	28531	611017	NP_001035363;NP_775826	NM_001040273;NM_173555	ENSP00000335673;ENSP00000287078	candidate	0	0	0	Eukaryotes	2	1	Cellular metabolism	-1	chr10	71899683	71906342	WES	pancreas
7307	U2AF1	U2 small nuclear RNA auxiliary factor 1	21q22.3	01871	12453	191317	NP_001020374;NP_001020375;NP_006749	NM_001025203;NM_001025204;NM_006758	ENSP00000369629;ENSP00000381205;ENSP00000291552	known	1	0	2	Eukaryotes	30	0	DNA/RNA metabolism and transcription,Regulation of transcription	88	chr21	44513215	44527604	CGC,WES	leukemia,myelodysplasia
11338	U2AF2	U2 small nuclear RNA auxiliary factor 2	19q13.42	01872	23156	191318	NP_001012496;NP_009210	NM_001012478;NM_007279	ENSP00000388475	candidate	0	0	0	Eukaryotes	48	0	DNA/RNA metabolism and transcription,Regulation of transcription	105	chr19	56166471	56185431	WES	chronic lymphocytic leukemia
7314	UBB	ubiquitin B	17p12-p11.2	06771	12463	191339	NP_061828	NM_018955	-	candidate	0	0	17	Last Universal Common Ancestor	160	1	Cell cycle,Cell motility and interactions,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Multicellular activities,Regulation of intracellular processes and metabolism,Regulation of transcription	36	chr17	16285222	16285908	WES	melanoma
7319	UBE2A	ubiquitin-conjugating enzyme E2A	Xq24	02422	12472	312180	NP_861442;NP_003327;NP_861427	NM_181777;NM_003336;NM_181762	ENSP00000360613;ENSP00000360624	candidate	0	0	1	Eukaryotes	64	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism	107	chrX	118708675	118717215	WES	lymphoma
7321	UBE2D1	ubiquitin-conjugating enzyme E2D 1	10q21.1	04267	12474	602961	NP_003329;NP_001191809	NM_003338;NM_001204880	-	candidate	0	0	4	Eukaryotes	99	4	Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction	64	chr10	60121098	60128522	WES	melanoma
7327	UBE2G2	ubiquitin-conjugating enzyme E2G 2	21q22.3	04387	12483	603124	NP_872630;NP_001189418;NP_003334	NM_182688;NM_001202489;NM_003343	ENSP00000338348	candidate	0	0	0	Eukaryotes	52	0	Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism	76	chr21	46191295	46207881	WGS	breast
63893	UBE2O	ubiquitin-conjugating enzyme E2O	17q25.1	10928	29554	-	NP_071349	NM_022066	ENSP00000323687	candidate	0	0	0	Eukaryotes	58	1	Regulation of intracellular processes and metabolism	20	chr17	74387027	74449223	WGS	prostate
143630	UBQLNL	ubiquilin-like	11p15.4	14472	28294	-	NP_659490	NM_145053	ENSP00000369531	candidate	0	0	0	Eukaryotes	0	0	Cellular metabolism,Cellular processes	-1	chr11	5536247	5537671	WES	colorectal
197131	UBR1	ubiquitin protein ligase E3 component n-recognin 1	15q13	09342	16808	605981	NP_777576	NM_174916	ENSP00000290650	candidate	0	0	0	Eukaryotes	67	1	Cellular metabolism	-1	chr15	43237530	43398220	WGS	lung
130507	UBR3	ubiquitin protein ligase E3 component n-recognin 3 (putative)	2q31.1	15887	30467	613831	NP_742067	NM_172070	ENSP00000396068	candidate	0	0	0	Eukaryotes	4	2	Cell response to stimuli,Cellular metabolism,Multicellular activities	-1	chr2	170684018	170938350	WGS	liver
51366	UBR5	ubiquitin protein ligase E3 component n-recognin 5	8q22	06436	16806	608413	NP_056986	NM_015902	ENSP00000429084	candidate	0	0	0	Metazoans	76	5	Cellular metabolism,Cellular processes,Signal transduction	106	chr8	103266533	103424462	HTMS,WES	breast,lung,ovarian,pancreas,prostate,colorectal
56886	UGGT1	UDP-glucose glycoprotein glucosyltransferase 1	2q14.3	12064	15663	605897	NP_064505	NM_020120;NM_001025777;NR_027671	ENSP00000259253	candidate	0	0	0	Eukaryotes	29	4	Cellular metabolism,Cellular processes	38	chr2	128848932	128945190	WGS	lymphoma
7365	UGT2B10	UDP glucuronosyltransferase 2 family, polypeptide B10	4q13.2	07193	12544	600070	NP_001138239;NP_001066	NM_001144767;NM_001075	-	candidate	0	0	9	Last Universal Common Ancestor	1	0	-1	-1	chr4	69681738	69696594	WES	melanoma
10720	UGT2B11	UDP glucuronosyltransferase 2 family, polypeptide B11	4q13.2	04345	12545	603064	NP_001064	NM_001073	ENSP00000387683	candidate	0	0	10	Last Universal Common Ancestor	0	0	Cellular metabolism	-1	chr4	70066161	70080440	WGS	chronic lymphocytic leukemia
115426	UHRF2	ubiquitin-like with PHD and ring finger domains 2	9p24.1	18257	12557	-	NP_690856	NM_152896	ENSP00000276893	candidate	0	0	1	Last Universal Common Ancestor	62	5	Cell cycle,Cellular metabolism,Cellular processes	-1	chr9	6413491	6506176	WES	colorectal
84747	UNC119B	unc-119 homolog B (C. elegans)	12q24.31	-	16488	-	NP_001074002	NM_032661;NM_001080533	ENSP00000344942	candidate	0	0	0	Eukaryotes	3	2	-1	91	chr12	121148278	121157832	WGS	chronic lymphocytic leukemia
440279	UNC13C	unc-13 homolog C (C. elegans)	15q21.3	-	23149	-	NP_001074003	NM_001080534	ENSP00000260323	candidate	0	0	0	Eukaryotes	5	2	Cellular processes,Signal transduction	-1	chr15	54305101	54919308	WES	chronic lymphocytic leukemia,pancreas
8633	UNC5C	unc-5 homolog C (C. elegans)	4q21-q23	04678	12569	603610	NP_003719	NM_003728	ENSP00000406022	candidate	0	0	0	Metazoans	2	1	Cell cycle,Cell motility and interactions,Development,Signal transduction	15	chr4	96090388	96470008	WES	lymphoma
137970	UNC5D	unc-5 homolog D (C. elegans)	8p12	11661	18634	-	NP_543148	NM_080872	ENSP00000394303	candidate	0	0	0	Metazoans	0	3	Cell cycle,Signal transduction	-1	chr8	35093303	35648078	WES	chronic lymphocytic leukemia,lymphoma
57578	UNC79	unc-79 homolog (C. elegans)	14q32.12	11143	19966	-	NP_065869	NM_020818	ENSP00000256339	candidate	0	0	0	Metazoans	62	3	-1	-1	chr14	93943987	94173247	WES	colorectal
285175	UNC80	unc-80 homolog (C. elegans)	2q35	12809	26582	612636	NP_115893;NP_872393	NM_032504;NM_182587	ENSP00000391088	candidate	0	0	0	Opisthokonts	6	0	-1	-1	chr2	210636797	210860316	WES	chronic lymphocytic leukemia
7385	UQCRC2	ubiquinol-cytochrome c reductase core protein II	16p12	01876	12586	191329	NP_003357	NM_003366	ENSP00000456232	candidate	0	0	0	Last Universal Common Ancestor	30	2	Cellular metabolism	109	chr16	21968556	21994489	WES	colorectal
7386	UQCRFS1	ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1	19q12	01874	12587	191327	NP_005994	NM_006003	-	candidate	0	0	1	Last Universal Common Ancestor	36	0	-1	109	chr19	29698458	29704025	WGS	melanoma
9816	URB2	URB2 ribosome biogenesis 2 homolog (S. cerevisiae)	1q42.13	17178	28967	-	NP_055592	NM_014777	ENSP00000258243	candidate	0	0	0	Eukaryotes	2	2	-1	19	chr1	229763381	229795041	WES	glioblastoma
7399	USH2A	Usher syndrome 2A (autosomal recessive, mild)	1q41	09759	12601	608400	NP_996816;NP_009054	NM_206933;NM_007123	ENSP00000355909;ENSP00000305941	candidate	0	0	0	Last Universal Common Ancestor	2	4	Cell response to stimuli,Development,Regulation of intracellular processes and metabolism	13	chr1	215799126	216595678	WES	breast,head and neck squamous cell carcinoma,pancreas
10600	USP16	ubiquitin specific peptidase 16	21q22.11	06881	12614	604735	NP_006438;NP_001027582;NP_001001992	NM_006447;NM_001032410;NM_001001992	ENSP00000382857;ENSP00000334808;ENSP00000382858	candidate	0	0	0	Eukaryotes	15	0	Cellular metabolism	100	chr21	30400235	30426505	HTMS	breast,lung,ovarian,pancreas,prostate
11274	USP18	ubiquitin specific peptidase 18	22q11.21	06136	12616	607057	NP_059110	NM_017414	ENSP00000215794	candidate	0	0	1	Eukaryotes	7	3	Cellular metabolism	10	chr22	18640431	18659581	HTMS	breast,lung,ovarian,pancreas,prostate
27005	USP21	ubiquitin specific peptidase 21	1q22	05291	12620	604729	NP_036607;NP_001014443	NM_012475;NM_001014443	ENSP00000356981;ENSP00000289865	candidate	0	0	0	Eukaryotes	56	2	Cellular metabolism,Cellular processes	94	chr1	161130431	161135234	HTMS	breast,lung,ovarian,pancreas,prostate
29761	USP25	ubiquitin specific peptidase 25	21q11.2	05296	12624	604736	NP_037528	NM_013396	ENSP00000285681	candidate	0	0	0	Eukaryotes	44	5	Cellular metabolism,Cellular processes	103	chr21	17102713	17250791	WGS	liver
83844	USP26	ubiquitin specific peptidase 26	Xq26.2	02255	13485	300309	NP_114113	NM_031907	-	candidate	0	0	0	Eukaryotes	4	0	Cellular metabolism	-1	chrX	132159510	132162248	WGS	liver
57646	USP28	ubiquitin specific peptidase 28	11q23	15632	12625	610748	NP_065937	NM_020886	ENSP00000003302	candidate	0	0	0	Eukaryotes	47	3	Cellular metabolism	-1	chr11	113669965	113746223	WGS	breast
57663	USP29	ubiquitin specific peptidase 29	19q13.43	07163	18563	609546	NP_065954	NM_020903	ENSP00000254181	candidate	0	0	0	Eukaryotes	3	1	Cellular metabolism,Cellular processes	29	chr19	57640044	57642809	HTMS	breast,lung,ovarian,pancreas,prostate
55230	USP40	ubiquitin specific peptidase 40	2q37.1	07166	20069	610570	NP_060688	NM_018218	ENSP00000415434	candidate	0	0	0	Eukaryotes	3	0	Cellular metabolism	-1	chr2	234386041	234474236	WGS	prostate
9098	USP6	ubiquitin specific peptidase 6 (Tre-2 oncogene)	17p13	06827	12629	604334	NP_004496	NM_004505;NM_005152	ENSP00000250066	known	1	0	0	Eukaryotes	14	1	Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism,Signal transduction	77	chr17	5033663	5076270	CGC	bone cyst
27340	UTP20	UTP20, small subunit (SSU) processome component, homolog (yeast)	12q23	09928	17897	612822	NP_055318	NM_014503	ENSP00000261637	candidate	0	0	0	Eukaryotes	13	3	Cell cycle,Regulation of intracellular processes and metabolism	55	chr12	101674061	101779898	WES	pancreas
7404	UTY	ubiquitously transcribed tetratricopeptide repeat gene, Y-linked	Yq11	02451	12638	400009	NP_872600;NP_009056;NP_872601	NM_182659;NM_007125;NM_182660	ENSP00000328939;ENSP00000355420;ENSP00000330446	candidate	0	0	1	Last Universal Common Ancestor	5	0	DNA/RNA metabolism and transcription	47	chrY	15362897	15591545	WES	bladder
7405	UVRAG	UV radiation resistance associated gene	11q13.5	03929	12640	602493	NP_003360	NM_003369	-	candidate	0	0	0	Eukaryotes	52	3	DNA/RNA metabolism and transcription	81	chr11	75526453	75852454	WGS	lung
81839	VANGL1	vang-like 1 (van gogh, Drosophila)	1p13.1	18279	15512	610132	NP_001165882;NP_001165883;NP_620409	NM_001172411;NM_001172412;NM_138959	ENSP00000347672	candidate	0	0	0	Metazoans	11	7	-1	51	chr1	116194035	116233997	WES	neuroblastoma
1462	VCAN	versican	5q14.3	00340	2464	118661	NP_001157570;NP_004376;NP_001157569;NP_001119808	NM_001164098;NM_004385;NM_001164097;NM_001126336	ENSP00000340062;ENSP00000342768;ENSP00000265077	candidate	0	0	0	Last Universal Common Ancestor	27	0	-1	100	chr5	82779338	82876250	WGS	melanoma
425054	VCX3B	variable charge, X-linked 3B	Xp22.31	15646	31838	-	NP_001001888	NM_001001888	ENSP00000370420	candidate	0	0	2	Primates	0	0	Development,Multicellular activities	-1	chrX	8433492	8434421	WGS	melanoma
79674	VEPH1	ventricular zone expressed PH domain homolog 1 (zebrafish)	3q24-q25	07782	25735	609594	NP_001161388;NP_001161387;NP_078897;NP_001161389;NP_001161383;NP_001161384	NM_001167916;NM_001167915;NM_024621;NM_001167917;NM_001167911;NM_001167912	ENSP00000376578;ENSP00000354919;ENSP00000419193;ENSP00000417268;ENSP00000443868	candidate	0	0	0	Metazoans	7	0	-1	-1	chr3	156978926	157213138	WES	breast
7428	VHL	von Hippel-Lindau tumor suppressor	3p25.3	01905	12687	608537	NP_000542;NP_937799	NM_000551;NM_198156	-	known	0	1	1	Metazoans	433	4	Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription	11	chr3	10183532	10191646	CGC,WES	hemangioma,kidney,pheochromocytoma
50853	VILL	villin-like	3p21.3	18283	30906	-	NP_056957	NM_015873	ENSP00000373266	candidate	0	0	0	Eukaryotes	0	1	Cellular metabolism,Cellular processes,Regulation of intracellular processes and metabolism	23	chr3	38035164	38048543	WES	chronic lymphocytic leukemia
7434	VIPR2	vasoactive intestinal peptide receptor 2	7q36.3	03576	12695	601970	NP_003373	NM_003382	ENSP00000262178	candidate	0	0	0	Vertebrates	1	0	Signal transduction	20	chr7	158823310	158937463	WGS	lung
317703	VN1R4	vomeronasal 1 receptor 4	19q13.42	18287	19871	-	NP_776256	NM_173857	ENSP00000310856	candidate	0	0	1	Vertebrates	0	0	Signal transduction	-1	chr19	53770016	53770918	WES	head and neck squamous cell carcinoma
9730	VPRBP	Vpr (HIV-1) binding protein	3p21.2	11674	30911	-	NP_055518;NP_001165375	NM_014703;NM_001171904	-	candidate	0	0	0	Eukaryotes	46	0	-1	38	chr3	51436203	51517844	WES	chronic lymphocytic leukemia
55237	VRTN	vertebrae development homolog (pig)	14q24.3	16593	20223	-	NP_060698	NM_018228	ENSP00000256362	candidate	0	0	0	Vertebrates	0	0	DNA/RNA metabolism and transcription	23	chr14	74823487	74825592	WES	colorectal
128434	VSTM2L	V-set and transmembrane domain containing 2 like	20q11.23	12735	16096	-	NP_542174	NM_080607	ENSP00000362560	candidate	0	0	0	Vertebrates	4	1	-1	-1	chr20	36531753	36572652	WGS	lymphoma
143187	VTI1A	vesicle transport through interaction with t-SNAREs homolog 1A (yeast)	10q25.2	18290	17792	614316	NP_660207	NM_145206	ENSP00000376792	known	1	0	0	Eukaryotes	11	0	Cellular processes	-1	chr10	114207132	114575139	CGC	colorectal
127731	VWA5B1	von Willebrand factor A domain containing 5B1	1p36.12	08732	26538	-	NP_001034589	NM_144623;NM_001039500	ENSP00000364230	candidate	0	0	0	Last Universal Common Ancestor	0	0	-1	-1	chr1	20637095	20680753	WGS	melanoma
80737	VWA7	von Willebrand factor A domain containing 7	6p21.33	12880	13939	609693	NP_079534	NM_025258	ENSP00000364840	candidate	0	0	0	Eukaryotes	1	1	Cell response to stimuli	8	chr6	31733374	31744556	WES	lymphoma
7450	VWF	von Willebrand factor	12p13.3	01906	12726	613160	NP_000543	NM_000552	ENSP00000261405	candidate	0	0	0	Last Universal Common Ancestor	11	0	Cellular metabolism,Multicellular activities	76	chr12	6058184	6232362	WES,WGS	pancreas,chronic lymphocytic leukemia
7454	WAS	Wiskott-Aldrich syndrome (eczema-thrombocytopenia)	Xp11.4-p11.21	02314	12731	300392	NP_000368	NM_000377	ENSP00000365891	known	0	1	0	Eukaryotes	35	0	Cellular metabolism,Cellular processes,Development,Immune system response,Multicellular activities	102	chrX	48542243	48549550	CGC	
51729	WBP11	WW domain binding protein 11	12p12.3	18293	16461	-	NP_057396	NM_016312	ENSP00000261167	candidate	0	0	3	Eukaryotes	49	4	DNA/RNA metabolism and transcription,Regulation of transcription	98	chr12	14940002	14954317	WGS	lung
84219	WDR24	WD repeat domain 24	16p13.3	15665	20852	-	NP_115635	NM_032259	ENSP00000293883	candidate	0	0	0	Last Universal Common Ancestor	4	0	-1	-1	chr16	734737	739640	WES	chronic lymphocytic leukemia
22884	WDR37	WD repeat domain 37	10p15.3	15668	31406	-	NP_054742	NM_014023	ENSP00000263150	candidate	0	0	0	Last Universal Common Ancestor	5	5	-1	99	chr10	1118096	1175281	WGS	glioblastoma
151790	WDR49	WD repeat domain 49	3q26.1	08160	26587	-	NP_849146	NM_178824	ENSP00000311343	candidate	0	0	0	Last Universal Common Ancestor	0	0	-1	-1	chr3	167196669	167322191	WGS	melanoma
79726	WDR59	WD repeat domain 59	16q23.1	13351	25706	-	NP_085058	NM_030581	ENSP00000262144	candidate	0	0	0	Last Universal Common Ancestor	5	1	-1	69	chr16	74908110	75018915	WGS	breast
256764	WDR72	WD repeat domain 72	15q21.3	10987	26790	613214	NP_877435	NM_182758	ENSP00000379619	candidate	0	0	0	Eukaryotes	755	0	-1	-1	chr15	53809899	54025346	WGS	lung
84128	WDR75	WD repeat domain 75	2q32.2	07775	25725	-	NP_115544	NM_032168	ENSP00000314193	candidate	0	0	0	Last Universal Common Ancestor	4	4	-1	-1	chr2	190306219	190340140	WES	pancreas
29062	WDR91	WD repeat domain 91	7q33	11035	24997	-	NP_054868	NM_014149	ENSP00000346466	candidate	0	0	0	Eukaryotes	4	1	-1	32	chr7	134870906	134896254	WES	breast
7468	WHSC1	Wolf-Hirschhorn syndrome candidate 1	4p16.3	04259	12766	602952	NP_579878;NP_579877;NP_579889;NP_579890;NP_001035889;NP_015627	NM_133331;NM_133330;NM_133336;NM_133334;NM_014919;NM_133333;NM_133335;NM_133332;NM_001042424;NM_007331	ENSP00000399251;ENSP00000372351;ENSP00000372348;ENSP00000381311;ENSP00000372347	known	1	0	0	Last Universal Common Ancestor	17	4	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	95	chr4	1902382	1980633	CGC	myeloma
54904	WHSC1L1	Wolf-Hirschhorn syndrome candidate 1-like 1	8p11.2	06155	12767	607083	NP_075447;NP_060248	NM_023034;NM_017778	ENSP00000313410;ENSP00000313983	known	1	0	0	Last Universal Common Ancestor	17	4	Cell cycle,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	64	chr8	38133162	38205689	CGC,Amplified	leukemia
11197	WIF1	WNT inhibitory factor 1	12q14.3	05541	18081	605186	NP_009122	NM_007191	ENSP00000286574	known	1	0	0	Eukaryotes	5	1	Signal transduction	37	chr12	65445132	65514971	CGC	salivary
147179	WIPF2	WAS/WASL interacting protein family, member 2	17q21.2	18304	30923	609692	NP_573571	NM_133264	-	candidate	0	0	0	Eukaryotes	23	0	-1	104	chr17	38416784	38433435	WES	head and neck squamous cell carcinoma
7471	WNT1	wingless-type MMTV integration site family, member 1	12q13	01276	12774	164820	NP_005421	NM_005430	-	candidate	0	0	0	Metazoans	12	3	Cell motility and interactions,Development,Signal transduction	14	chr12	49372434	49375420	WGS	melanoma
55135	WRAP53	WD repeat containing, antisense to TP53	17p13.1	07670	25522	612661	NP_060551;NP_001137462;NP_001137463;NP_001137464	NM_018081;NM_001143990;NM_001143991;NM_001143992	ENSP00000397219;ENSP00000411061;ENSP00000379727;ENSP00000434999	candidate	0	0	0	Last Universal Common Ancestor	8	3	-1	105	chr17	7591967	7606801	WGS	prostate
7486	WRN	Werner syndrome, RecQ helicase-like	8p12	05212	12791	604611	NP_000544	NM_000553	ENSP00000298139	known	0	1	0	Last Universal Common Ancestor	46	0	Cell cycle,Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism	24	chr8	30915964	31030615	CGC	
7490	WT1	Wilms tumor 1	11p13	06163	12796	607102	NP_000369;NP_077744;NP_001185480;NP_077742;NP_001185481	NM_000378;NM_024426;NM_001198551;NM_024424;NM_024425;NM_001198552	ENSP00000415516;ENSP00000368370;ENSP00000435307;ENSP00000331327	known	0	1	0	Last Universal Common Ancestor	29	3	Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	16	chr11	32410607	32456888	CGC	desmoplastic small round cell tumor,Wilms
11059	WWP1	WW domain containing E3 ubiquitin protein ligase 1	8q21	03811	17004	602307	NP_008944	NM_007013	ENSP00000427793	candidate	0	0	1	Eukaryotes	18	0	Cell motility and interactions,Cellular metabolism,Cellular processes,DNA/RNA metabolism and transcription,Development,Other,Regulation of intracellular processes and metabolism,Regulation of transcription,Signal transduction	94	chr8	87386280	87479119	WGS	liver
25937	WWTR1	WW domain containing transcription regulator 1	3q23-q24	09580	24042	607392	NP_001161752;NP_056287;NP_001161750	NM_001168280;NM_015472;NM_001168278	ENSP00000419465	known	1	0	0	Eukaryotes	20	2	Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription	75	chr3	149238595	149375093	CGC,WGS	epitheliod hemangioendothelioma,breast
7498	XDH	xanthine dehydrogenase	2p23.1	06363	12805	607633	NP_000370	NM_000379	ENSP00000368727	candidate	0	0	0	Last Universal Common Ancestor	4	1	Development,Multicellular activities	75	chr2	31558827	31637532	WES	breast
165904	XIRP1	xin actin-binding repeat containing 1	3p22.2	16727	14301	609777	NP_919269;NP_001185550	NM_194293;NM_001198621	ENSP00000379550;ENSP00000343140	candidate	0	0	0	Vertebrates	1	1	Cellular processes	-1	chr3	39225408	39230936	WES	breast
129446	XIRP2	xin actin-binding repeat containing 2	2q24.3	10267	14303	609778	NP_689594;NP_001186074;NP_001186073;NP_001186072;NP_001073278	NM_152381;NM_001199145;NM_001199144;NM_001199143;NM_001079810	ENSP00000386454;ENSP00000386619;ENSP00000387255;ENSP00000386981;ENSP00000386840	candidate	0	0	0	Vertebrates	8	1	Cellular processes	-1	chr2	167759993	168110633	WES,WGS	cholangiocarcinoma,melanoma
7507	XPA	xeroderma pigmentosum, complementation group A	9q22.3	02045	12814	611153	NP_000371	NR_027302;NM_000380	ENSP00000364270	known	0	1	0	Eukaryotes	31	3	Cellular metabolism,DNA/RNA metabolism and transcription	26	chr9	100437724	100459574	CGC	
7508	XPC	xeroderma pigmentosum, complementation group C	3p25	02046	12816	613208	NP_001139241;NP_004619	NR_027299;NM_001145769;NM_004628	ENSP00000285021	known	0	1	0	Eukaryotes	41	1	Cell cycle,Cell response to stimuli,Cellular metabolism,DNA/RNA metabolism and transcription,Signal transduction	96	chr3	14187444	14220068	CGC	
7512	XPNPEP2	X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound	Xq25	02144	12823	300145	NP_003390	NM_003399	ENSP00000360147	candidate	0	0	0	Last Universal Common Ancestor	0	0	Cellular metabolism	49	chrX	128873190	128902458	WES	lung
7514	XPO1	exportin 1 (CRM1 homolog, yeast)	2p15	03975	12825	602559	NP_003391	NM_003400	ENSP00000384863	known	1	0	0	Eukaryotes	150	6	Cell response to stimuli,Cellular processes,DNA/RNA metabolism and transcription	107	chr2	61705958	61761032	CGC,WES,WGS	leukemia,chronic lymphocytic leukemia
23039	XPO7	exportin 7	8p21	05846	14108	606140	NP_055839	NM_015024;NM_001100162;NM_001100161	ENSP00000252512	candidate	0	0	0	Eukaryotes	14	7	Cellular processes,DNA/RNA metabolism and transcription	83	chr8	21824365	21862596	WES	acute myeloid leukemia
7516	XRCC2	X-ray repair complementing defective repair in Chinese hamster cells 2	7q36.1	02656	12829	600375	NP_005422	NM_005431	ENSP00000352271	candidate	0	0	0	Eukaryotes	3	4	Cell cycle,DNA/RNA metabolism and transcription	74	chr7	152345730	152357867	WGS	liver
54464	XRN1	5'-3' exoribonuclease 1	3q23	10470	30654	607994	NP_061874;NP_001036069	NM_019001;NM_001042604	ENSP00000264951	candidate	0	0	0	Eukaryotes	45	4	Cell cycle,Regulation of intracellular processes and metabolism	-1	chr3	142030356	142166786	WGS	lymphoma
10413	YAP1	Yes-associated protein 1	11q13	09424	16262	606608	NP_001181973;NP_006097;NP_001181974;NP_001123617	NM_001195044;NM_006106;NM_001195045;NM_001130145	ENSP00000282441;ENSP00000445635;ENSP00000331023	known	0	0	1	Eukaryotes	20	5	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	26	chr11	101981580	102100668	CGC,Amplified	
8089	YEATS4	YEATS domain containing 4	12q13-q15	03666	24859	602116	NP_006521	NM_006530	ENSP00000247843	known	0	0	0	Last Universal Common Ancestor	32	0	Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	33	chr12	69753753	69784093	CGC,Amplified	
7529	YWHAB	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide	20q13.1	03184	12849	601289	NP_647539;NP_003395	NM_139323;NM_003404	ENSP00000361930;ENSP00000300161	known	0	0	13	Eukaryotes	321	0	Cell cycle,Cellular processes,Development,Regulation of intracellular processes and metabolism,Signal transduction	109	chr20	43530175	43535076	CGC,Amplified	
7531	YWHAE	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	17p13.3	05457	12851	605066	NP_006752	NM_006761;NR_024058	ENSP00000264335	known	1	0	5	Eukaryotes	120	1	Signal transduction	105	chr17	1248744	1303404	CGC	sarcoma
10971	YWHAQ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide	2p25.1	00886	12854	609009	NP_006817	NM_006826	ENSP00000238081	known	0	0	10	Eukaryotes	104	3	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	109	chr2	9725418	9770581	CGC,Amplified	
7534	YWHAZ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide	8q23.1	03183	12855	601288	NP_003397;NP_001129173;NP_001129171;NP_001129174;NP_663723;NP_001129172	NM_003406;NM_001135701;NM_001135699;NM_001135702;NM_145690;NM_001135700	ENSP00000398599;ENSP00000379286;ENSP00000309503;ENSP00000379288	known	0	0	15	Eukaryotes	707	5	Cell cycle,Development,Regulation of intracellular processes and metabolism,Signal transduction	109	chr8	101932924	101961117	CGC,Amplified	
7455	ZAN	zonadhesin	7q22	03846	12857	602372	NP_775082;NP_003377	NM_173059;NM_173057;NM_173058;NM_173056;NM_003386;NM_173055	ENSP00000422387;ENSP00000423579	candidate	0	0	0	Last Universal Common Ancestor	0	0	Cell motility and interactions,Development	-1	chr7	100331792	100395244	WES	pancreas
7704	ZBTB16	zinc finger and BTB domain containing 16	11q23.1	11762	12930	176797	NP_001018011;NP_005997	NM_001018011;NM_006006	ENSP00000376721;ENSP00000338157	known	1	0	0	Last Universal Common Ancestor	163	0	Cell cycle,Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription	86	chr11	113934023	114121274	CGC	leukemia
360023	ZBTB41	zinc finger and BTB domain containing 41	1q31.3	17017	24819	-	NP_919290	NM_194314	-	candidate	0	0	0	Last Universal Common Ancestor	2	2	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	-1	chr1	197128492	197169603	WGS	melanoma
9877	ZC3H11A	zinc finger CCCH-type containing 11A	1q32.1	11100	29093	613513	NP_055642	NM_014827	ENSP00000333253	candidate	0	0	2	Eukaryotes	26	6	-1	109	chr1	203786199	203821524	WGS	lung
57683	ZDBF2	zinc finger, DBF-type containing 2	2q33.3	-	29313	-	NP_065974	NM_020923	ENSP00000363545	candidate	0	0	0	Vertebrates	1	0	-1	-1	chr2	207146574	207176314	WES	lung
463	ZFHX3	zinc finger homeobox 3	16q22.3	00075	777	104155	NP_001158238;NP_008816	NM_001164766;NM_006885	ENSP00000438926;ENSP00000268489	candidate	0	0	0	Eukaryotes	10	6	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	9	chr16	72821066	72994044	WES	bladder,prostate
79776	ZFHX4	zinc finger homeobox 4	8q21.11	09503	30939	606940	NP_078997	NM_024721	ENSP00000430497	candidate	0	0	0	Eukaryotes	1	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	58	chr8	77616324	77776798	WES	head and neck squamous cell carcinoma
677	ZFP36L1	zinc finger protein 36, C3H type-like 1	14q22-q24	03041	1107	601064	NP_004917;NP_001231627;NP_001231630	NM_004926;NM_001244698;NM_001244701	ENSP00000388402	candidate	0	0	0	Eukaryotes	3	4	Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription	106	chr14	69256253	69262866	WES	breast
55734	ZFP64	zinc finger protein 64 homolog (mouse)	20q13.2	15728	15940	-	NP_060667;NP_955459;NP_955458;NP_071371	NM_018197;NM_199427;NM_199426;NM_022088	ENSP00000216923;ENSP00000344615;ENSP00000360570;ENSP00000355179	candidate	0	0	0	Last Universal Common Ancestor	18	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	78	chr20	50768688	50808175	WES	breast
23503	ZFYVE26	zinc finger, FYVE domain containing 26	14q24.1	15734	20761	612012	NP_056161	NM_015346	ENSP00000251119	candidate	0	0	0	Eukaryotes	0	4	-1	61	chr14	68215156	68282680	WES,WGS	breast,glioblastoma
22882	ZHX2	zinc fingers and homeoboxes 2	8q24.13	16458	18513	609185	NP_055758	NM_014943	ENSP00000314709	candidate	0	0	0	Metazoans	16	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	63	chr8	123963751	123966261	WES	neuroblastoma
7547	ZIC3	Zic family member 3	Xq26.2	02225	12874	300265	NP_003404	NM_003413	ENSP00000287538	candidate	0	0	0	Last Universal Common Ancestor	1	1	Cellular metabolism,DNA/RNA metabolism and transcription,Development,Regulation of intracellular processes and metabolism,Regulation of transcription	17	chrX	136648851	136652226	WGS	liver
23619	ZIM2	zinc finger, imprinted 2	19q13.4	10321	12875	-	NP_001139799;NP_001139798;NP_056178	NM_001146327;NM_001146326;NM_015363	ENSP00000470326;ENSP00000375589;ENSP00000221722	candidate	0	0	-1	Last Universal Common Ancestor	0	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	18	-	0	0	WES	pancreas
7750	ZMYM2	zinc finger, MYM-type 2	13q11-q12	03745	12989	602221	NP_003444;NP_001177894;NP_932072;NP_001177893	NM_003453;NM_001190965;NM_197968;NM_001190964	ENSP00000413744;ENSP00000372322	known	1	0	0	Metazoans	39	3	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	89	chr13	20567213	20660151	CGC,HTMS	myeloma,non-hodgkin lymphoma,breast,lung,ovarian,pancreas,prostate
9203	ZMYM3	zinc finger, MYM-type 3	Xq13.1	02088	13054	300061	NP_963893;NP_001164633;NP_005087;NP_001164634	NM_201599;NM_001171162;NM_005096;NM_001171163	ENSP00000363110;ENSP00000363093;ENSP00000343909;ENSP00000322845	candidate	0	0	0	Metazoans	4	0	-1	94	chrX	70460769	70473105	WGS	medulloblastoma
9202	ZMYM4	zinc finger, MYM-type 4	1p32-p34	10326	13055	613568	NP_005086	NM_005095	ENSP00000322915	candidate	0	0	0	Metazoans	8	0	-1	89	chr1	35790961	35885275	WES	colorectal
51364	ZMYND10	zinc finger, MYND-type containing 10	3p21.3	06145	19412	607070	NP_056980	NM_015896	ENSP00000353289	candidate	0	0	0	Eukaryotes	5	0	-1	54	chr3	50378844	50383010	HTMS	lung
7764	ZNF217	zinc finger protein 217	20q13.2	04272	13009	602967	NP_006517	NM_006526	ENSP00000304308	known	0	0	0	Eukaryotes	10	9	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	47	chr20	52188286	52199365	CGC,WGS,Amplified	melanoma
7769	ZNF226	zinc finger protein 226	19q13.2	15751	13019	-	NP_057003;NP_001027544;NP_001139692;NP_001027545;NP_001027546	NM_015919;NM_016444;NM_001032372;NM_001146220;NM_001032375;NM_001032373;NM_001032374	ENSP00000393265;ENSP00000336719;ENSP00000300823	candidate	0	0	0	Last Universal Common Ancestor	4	3	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	49	chr19	44676241	44679183	WGS	liver
55609	ZNF280C	zinc finger protein 280C	Xq26.1	06526	25955	-	NP_060136	NM_017666	ENSP00000360017	candidate	0	0	0	Eukaryotes	2	2	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	-1	chrX	129339272	129380977	WGS	melanoma
57567	ZNF319	zinc finger protein 319	16q21	18326	13644	-	NP_065858	NM_020807	ENSP00000299237	candidate	0	0	0	Last Universal Common Ancestor	1	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	-1	chr16	58030424	58032169	WGS	lymphoma
55422	ZNF331	zinc finger protein 331	19q13.42	05827	15489	606043	NP_001240729;NP_001240730;NP_001240727;NP_001073376;NP_001240728;NP_061025;NP_001073375	NM_001253800;NM_001253801;NM_001253798;NM_001079907;NM_001253799;NM_018555;NM_001079906	ENSP00000253144	known	1	0	0	Last Universal Common Ancestor	14	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	98	chr19	54079950	54081203	CGC	thyroid
7587	ZNF37A	zinc finger protein 37A	10p11.2	18508	13102	-	NP_001171572;NP_001007095;NP_003412	NM_001178101;NM_001007094;NM_003421	ENSP00000329141;ENSP00000354377	candidate	0	0	0	Last Universal Common Ancestor	0	1	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	9	chr10	38403680	38407762	WGS	chronic lymphocytic leukemia
171017	ZNF384	zinc finger protein 384	12p12	18332	11955	609951	NP_001129206;NP_597733;NP_001035009	NM_001135734;NM_001039918;NM_133476;NM_001039917;NM_001039920;NM_001039919;NM_001039916	ENSP00000348018;ENSP00000380019;ENSP00000380013	known	1	0	0	Last Universal Common Ancestor	8	5	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	80	chr12	6776883	6788686	CGC	leukemia
346157	ZNF391	zinc finger protein 391	6p22.1	18461	18779	-	NP_001070249	NM_001076781;NM_001013719	-	candidate	0	0	0	Last Universal Common Ancestor	0	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	31	chr6	27368150	27369223	WES	pancreas
55628	ZNF407	zinc finger protein 407	18q23	11713	19904	-	NP_001139662;NP_001139661;NP_060227	NM_001146190;NM_001146189;NM_017757	ENSP00000463270;ENSP00000310359;ENSP00000299687	candidate	0	0	0	Last Universal Common Ancestor	7	3	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	10	chr18	72342976	72776421	WGS	prostate
79973	ZNF442	zinc finger protein 442	19p13.2	15795	20877	-	NP_110451	NM_030824	ENSP00000242804	candidate	0	0	4	Last Universal Common Ancestor	1	1	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	9	chr19	12460518	12463928	WES	colorectal
162968	ZNF497	zinc finger protein 497	19q13.43	15806	23714	-	NP_001193938;NP_940860	NM_001207009;NM_198458	ENSP00000311183	candidate	0	0	0	Last Universal Common Ancestor	0	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	-1	chr19	58867508	58869001	WES	glioblastoma
9849	ZNF518A	zinc finger protein 518A	10q24.1	18349	29009	-	NP_055618	NM_014803	-	candidate	0	0	0	Eukaryotes	2	1	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	61	chr10	97916080	97920527	WGS	chronic lymphocytic leukemia,glioblastoma
25925	ZNF521	zinc finger protein 521	18q11.2	18350	24605	610974	NP_056276	NM_015461	ENSP00000354794	known	1	0	0	Last Universal Common Ancestor	0	2	-1	-1	chr18	22669429	22930910	CGC,WES	leukemia,colorectal,lung,lymphoma
9745	ZNF536	zinc finger protein 536	19q12	15825	29025	-	NP_055532	NM_014717	ENSP00000347730	candidate	0	0	0	Eukaryotes	1	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	63	chr19	30934470	31040426	WES	lung
84527	ZNF559	zinc finger protein 559	19p13.2	18352	28197	-	NP_001189340;NP_001189336;NP_115886;NP_001189335;NP_001189337;NP_001189339;NP_001189338;NP_001189341	NM_001202411;NM_001202407;NM_032497;NM_001202406;NM_001202408;NM_001202410;NM_001202409;NM_001202412	ENSP00000325393;ENSP00000468153	candidate	0	0	0	Last Universal Common Ancestor	4	2	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	-1	chr19	9449869	9453741	WGS	lung
147741	ZNF560	zinc finger protein 560	19p13.2	15842	26484	-	NP_689689	NM_152476	ENSP00000301480	candidate	0	0	0	Last Universal Common Ancestor	1	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	-1	chr19	9577253	9585001	WGS	liver
148266	ZNF569	zinc finger protein 569	19q13.12	15849	24737	613904	NP_689697	NM_152484	ENSP00000325018	candidate	0	0	0	Last Universal Common Ancestor	2	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	-1	chr19	37903502	37905322	WES	breast
137209	ZNF572	zinc finger protein 572	8q24.13	15851	26758	-	NP_689625	NM_152412	ENSP00000319305	candidate	0	0	0	Last Universal Common Ancestor	0	1	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	-1	chr8	125988589	125990097	WES	head and neck squamous cell carcinoma
152687	ZNF595	zinc finger protein 595	4p16.3	15868	27196	-	NP_872330	NM_182524	-	candidate	0	0	2	Eukaryotes	2	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	-1	chr4	85621	87314	WES	prostate
27332	ZNF638	zinc finger protein 638	2p13.1	11736	17894	614349	NP_001014972;NP_001239541;NP_001239542;NP_055312	NM_001014972;NM_001252612;NM_001252613;NM_014497	ENSP00000386433;ENSP00000264447	candidate	0	0	0	Metazoans	38	3	DNA/RNA metabolism and transcription,Regulation of transcription	103	chr2	71576085	71661934	WES	pancreas
51193	ZNF639	zinc finger protein 639	3q26.33	15882	30950	-	NP_057415	NM_016331	ENSP00000325634	known	0	0	0	Eukaryotes	6	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	14	chr3	179046082	179052207	CGC,Amplified	
9726	ZNF646	zinc finger protein 646	16p11.2	15886	29004	-	NP_055514	NM_014699	ENSP00000300850	candidate	0	0	0	Eukaryotes	9	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	36	chr16	31087646	31094410	WES,WGS	breast,prostate
79759	ZNF668	zinc finger protein 668	16p11.2	07828	25821	-	NP_001166139;NP_001166140;NP_078982;NP_001166141	NM_001172668;NM_001172669;NM_024706;NM_001172670	ENSP00000440149;ENSP00000442573;ENSP00000441349;ENSP00000300849	candidate	0	0	0	Last Universal Common Ancestor	4	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	0	chr16	31072392	31075939	WES	breast
57592	ZNF687	zinc finger protein 687	1q21.3	13859	29277	610568	NP_065883	NM_020832	ENSP00000336620	candidate	0	0	0	Eukaryotes	11	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	-1	chr1	151258768	151263682	WES	glioblastoma
7620	ZNF69	zinc finger protein 69	19p13.2	11836	13138	194543	NP_068734	NM_021915	ENSP00000345333	candidate	0	0	3	Last Universal Common Ancestor	0	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	-1	chr19	11998739	12015701	WGS	lung
374928	ZNF773	zinc finger protein 773	19q13.43	14655	30487	-	NP_940944	NM_198542	ENSP00000282292	candidate	0	0	1	Last Universal Common Ancestor	3	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	-1	chr19	58016025	58018789	WGS	lung
136051	ZNF786	zinc finger protein 786	7q36.1	13232	21806	-	NP_689624	NM_152411	ENSP00000417470	candidate	0	0	0	Last Universal Common Ancestor	0	0	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	-1	chr7	148767518	148777809	WGS	breast
90576	ZNF799	zinc finger protein 799	19p13.2	-	28071	-	NP_001074290	NM_203381;NM_001080821	ENSP00000411084	candidate	0	0	3	Last Universal Common Ancestor	1	2	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	-1	chr19	12501283	12504237	WGS	breast
91752	ZNF804A	zinc finger protein 804A	2q32.1	12804	21711	612282	NP_919226	NM_194250	ENSP00000303252	candidate	0	0	0	Vertebrates	3	1	-1	25	chr2	185463687	185803750	WES	kidney
219578	ZNF804B	zinc finger protein 804B	7q21.13	08721	21958	-	NP_857597	NM_181646	ENSP00000329638	candidate	0	0	0	Eukaryotes	0	1	-1	-1	chr7	88389291	88966343	WES	head and neck squamous cell carcinoma
55552	ZNF823	zinc finger protein 823	19p13.2	-	30936	-	NP_001073962	NM_001080493	ENSP00000340683	candidate	0	0	6	Last Universal Common Ancestor	4	2	Cellular metabolism,DNA/RNA metabolism and transcription,Regulation of intracellular processes and metabolism,Regulation of transcription	-1	chr19	11832519	11836142	WES	head and neck squamous cell carcinoma
91603	ZNF830	zinc finger protein 830	17q12	14469	28291	-	NP_443089	NM_052857	ENSP00000354518	candidate	0	0	0	Eukaryotes	14	0	Cell cycle,Development	-1	chr17	33288586	33289701	WES	lymphoma
128611	ZNF831	zinc finger protein 831	20q13.32	-	16167	-	NP_848552	NM_178457	ENSP00000360069	candidate	0	0	0	Eukaryotes	0	0	-1	-1	chr20	57766075	57829795	WES	melanoma
8233	ZRSR2	zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2	Xp22.1	02068	23019	300028	NP_005080	NM_005089	ENSP00000303015	known	0	1	2	Eukaryotes	5	0	DNA/RNA metabolism and transcription,Regulation of transcription	97	chrX	15808619	15841362	CGC,WES,WGS	leukemia,myelodysplasia,breast
140831	ZSWIM3	zinc finger, SWIM-type containing 3	20q13.12	15903	16157	-	NP_542790	NR_037628;NM_080752	ENSP00000255152	candidate	0	0	0	Eukaryotes	1	2	-1	-1	chr20	44486465	44507285	WES	gastric
55055	ZWILCH	Zwilch, kinetochore associated, homolog (Drosophila)	15q22.31	07640	25468	609984	NP_060445	NM_017975;NR_003105	ENSP00000311429	candidate	0	0	0	Eukaryotes	6	0	Cell cycle	7	chr15	66797677	66839014	WES	lymphoma
23140	ZZEF1	zinc finger, ZZ-type with EF-hand domain 1	17p13.2	15906	29027	-	NP_055928	NM_015113	ENSP00000371051	candidate	0	0	0	Eukaryotes	7	0	Cell cycle	86	chr17	3910187	4046189	WES	gastric
